CCL19 — 12 ClinVar variants
All ClinVar germline CCL19 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 12 flagged for review →
12 Uncertain significance
Full CCL19 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 12
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 5
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 7
The independent predictors disagree with each other — read with care.
- CCL19 p.Arg81Cys Uncertain significance Single submitter
- CCL19 p.Arg95His Uncertain significance Single submitter
- CCL19 p.Asp53His Uncertain significance Single submitter
- CCL19 p.Gln76Arg Uncertain significance Single submitter
- CCL19 p.Ile38Val Uncertain significance Single submitter
- CCL19 p.Leu5Val Uncertain significance Single submitter
- CCL19 p.Thr63Ile Uncertain significance Single submitter
All CCL19 variants
Uncertain significance 12
- p.Arg81Cys Single submitter ⚠
- p.Arg95His Single submitter ⚠
- p.Asn45Lys Single submitter ⚠
- p.Asp53His Single submitter ⚠
- p.Gln76Arg Single submitter ⚠
- p.Ile38Val Single submitter ⚠
- p.Leu5Val Single submitter ⚠
- p.Lys52Glu Single submitter ⚠
- p.Pro16Ala Single submitter ⚠
- p.Ser98Asn Single submitter ⚠
- p.Thr63Ile Single submitter ⚠
- p.Tyr41Ser Single submitter ⚠