CCL24 — 15 ClinVar variants
All ClinVar germline CCL24 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 13 flagged for review →
2 Likely benign · 13 Uncertain significance
Full CCL24 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 13
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 9
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CCL24 p.Ala104Ser Uncertain significance Single submitter
- CCL24 p.Ala96Thr Uncertain significance Single submitter
- CCL24 p.Arg46Leu Uncertain significance Single submitter
- CCL24 p.Cys74Tyr Uncertain significance Single submitter
- CCL24 p.Gly3Ala Uncertain significance Single submitter
- CCL24 p.Lys78Arg Uncertain significance Single submitter
- CCL24 p.Lys95Glu Uncertain significance Single submitter
- CCL24 p.Met86Val Uncertain significance Single submitter
- CCL24 p.Pro98Ala Uncertain significance Single submitter
Predictors split 4
The independent predictors disagree with each other — read with care.
All CCL24 variants
Likely benign 2
- p.Arg99Gly Single submitter
- p.Gly107Val Single submitter
Uncertain significance 13
- p.Ala104Ser Single submitter ⚠
- p.Ala96Thr Single submitter ⚠
- p.Arg46Leu Single submitter ⚠
- p.Asp76Asn Single submitter ⚠
- p.Cys74Tyr Single submitter ⚠
- p.Gly3Ala Single submitter ⚠
- p.Leu11Phe Single submitter ⚠
- p.Lys78Arg Single submitter ⚠
- p.Lys95Glu Single submitter ⚠
- p.Met86Val Single submitter ⚠
- p.Pro77His Single submitter ⚠
- p.Pro98Ala Single submitter ⚠
- p.Trp81Gly Single submitter ⚠