CCL7 — 11 ClinVar variants
All ClinVar germline CCL7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 11 flagged for review →
11 Uncertain significance
Full CCL7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 11
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 4
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 7
The independent predictors disagree with each other — read with care.
- CCL7 p.Ala63Thr Uncertain significance Single submitter
- CCL7 p.Ala76Thr Uncertain significance Single submitter
- CCL7 p.Asp85His Uncertain significance Single submitter
- CCL7 p.Phe38Leu Uncertain significance Single submitter
- CCL7 p.Pro44Arg Uncertain significance Single submitter
- CCL7 p.Thr94Ile Uncertain significance Single submitter
- CCL7 p.Tyr36Cys Uncertain significance Single submitter
All CCL7 variants
Uncertain significance 11
- p.Ala63Thr Single submitter ⚠
- p.Ala76Asp Single submitter ⚠
- p.Ala76Thr Single submitter ⚠
- p.Asp71Glu Single submitter ⚠
- p.Asp85His Single submitter ⚠
- p.Phe38Leu Single submitter ⚠
- p.Pro44Arg Single submitter ⚠
- p.Thr94Ile Single submitter ⚠
- p.Thr96Ile Single submitter ⚠
- p.Trp82Gly Single submitter ⚠
- p.Tyr36Cys Single submitter ⚠