CCNJ — 40 ClinVar variants
All ClinVar germline CCNJ variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 37 flagged for review →
3 Likely benign · 37 Uncertain significance
Full CCNJ gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 37
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 21
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CCNJ p.Arg218His Uncertain significance Single submitter
- CCNJ p.Arg229Cys Uncertain significance Single submitter
- CCNJ p.Arg281Gln Uncertain significance Single submitter
- CCNJ p.Arg53His Uncertain significance Single submitter
- CCNJ p.Asn52Ser Uncertain significance Single submitter
- CCNJ p.Gln269Pro Uncertain significance Single submitter
- CCNJ p.Gln308Pro Uncertain significance Single submitter
- CCNJ p.Gly10Glu Uncertain significance Single submitter
- CCNJ p.Gly113Ser Uncertain significance Single submitter
- CCNJ p.Gly5Val Uncertain significance Single submitter
- CCNJ p.His129Arg Uncertain significance Single submitter
- CCNJ p.Leu339Pro Uncertain significance Single submitter
- CCNJ p.Met170Val Uncertain significance Single submitter
- CCNJ p.Phe332Leu Uncertain significance Single submitter
- CCNJ p.Ser306Leu Uncertain significance Single submitter
- CCNJ p.Thr222Ala Uncertain significance Single submitter
- CCNJ p.Thr222Met Uncertain significance Single submitter
- CCNJ p.Thr231Ser Uncertain significance Single submitter
- CCNJ p.Thr294Ala Uncertain significance Single submitter
- CCNJ p.Thr344Ala Uncertain significance Single submitter
- CCNJ p.Val336Ile Uncertain significance Single submitter
Predictors split 16
The independent predictors disagree with each other — read with care.
- CCNJ p.Ala158Gly Uncertain significance Single submitter
- CCNJ p.Ala232Val Uncertain significance Single submitter
- CCNJ p.Ala60Thr Uncertain significance Single submitter
- CCNJ p.Arg218Pro Uncertain significance Single submitter
- CCNJ p.Arg281Trp Uncertain significance Single submitter
- CCNJ p.Asn251Ile Uncertain significance Single submitter
- CCNJ p.Asp236Asn Uncertain significance Single submitter
- CCNJ p.Gly32Ser Uncertain significance Single submitter
- CCNJ p.His249Arg Uncertain significance Single submitter
- CCNJ p.His284Asp Uncertain significance Single submitter
- CCNJ p.Ile16Val Uncertain significance Single submitter
- CCNJ p.Leu230Val Uncertain significance Single submitter
- CCNJ p.Ser335Asn Uncertain significance Single submitter
- CCNJ p.Thr305Met Uncertain significance Single submitter
- CCNJ p.Thr334Ile Uncertain significance Single submitter
- CCNJ p.Val210Leu Uncertain significance Single submitter
All CCNJ variants
Likely benign 3
Uncertain significance 37
- p.Ala158Gly Single submitter ⚠
- p.Ala232Val Single submitter ⚠
- p.Ala60Thr Single submitter ⚠
- p.Arg218His Single submitter ⚠
- p.Arg218Pro Single submitter ⚠
- p.Arg229Cys Single submitter ⚠
- p.Arg281Gln Single submitter ⚠
- p.Arg281Trp Single submitter ⚠
- p.Arg53His Single submitter ⚠
- p.Asn251Ile Single submitter ⚠
- p.Asn52Ser Single submitter ⚠
- p.Asp236Asn Single submitter ⚠
- p.Gln269Pro Single submitter ⚠
- p.Gln308Pro Single submitter ⚠
- p.Gly10Glu Single submitter ⚠
- p.Gly113Ser Single submitter ⚠
- p.Gly32Ser Single submitter ⚠
- p.Gly5Val Single submitter ⚠
- p.His129Arg Single submitter ⚠
- p.His249Arg Single submitter ⚠
- p.His284Asp Single submitter ⚠
- p.Ile16Val Single submitter ⚠
- p.Leu230Val Single submitter ⚠
- p.Leu339Pro Single submitter ⚠
- p.Met170Val Single submitter ⚠
- p.Phe332Leu Single submitter ⚠
- p.Ser306Leu Single submitter ⚠
- p.Ser335Asn Single submitter ⚠
- p.Thr222Ala Single submitter ⚠
- p.Thr222Met Single submitter ⚠
- p.Thr231Ser Single submitter ⚠
- p.Thr294Ala Single submitter ⚠
- p.Thr305Met Single submitter ⚠
- p.Thr334Ile Single submitter ⚠
- p.Thr344Ala Single submitter ⚠
- p.Val210Leu Single submitter ⚠
- p.Val336Ile Single submitter ⚠