CD160 — 18 ClinVar variants
All ClinVar germline CD160 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 16 flagged for review →
1 Benign · 1 Likely benign · 16 Uncertain significance
Full CD160 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 16
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 12
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CD160 p.Gln101His Uncertain significance Single submitter
- CD160 p.Gln117Arg Uncertain significance Single submitter
- CD160 p.Gln164Pro Uncertain significance Single submitter
- CD160 p.Glu54Asp Uncertain significance Single submitter
- CD160 p.Glu90Lys Uncertain significance Single submitter
- CD160 p.His106Arg Uncertain significance Single submitter
- CD160 p.His126Arg Uncertain significance Single submitter
- CD160 p.Ile14Val Uncertain significance Single submitter
- CD160 p.Leu178Phe Uncertain significance Single submitter
- CD160 p.Phe151Tyr Uncertain significance Single submitter
- CD160 p.Thr72Asn Uncertain significance Single submitter
- CD160 p.Val19Met Uncertain significance Single submitter
Predictors split 4
The independent predictors disagree with each other — read with care.
All CD160 variants
Benign 1
- p.Gly84Arg Multiple submitters
Likely benign 1
- p.Arg39Gln Single submitter
Uncertain significance 16
- p.Arg122Cys Single submitter ⚠
- p.Gln101His Single submitter ⚠
- p.Gln117Arg Single submitter ⚠
- p.Gln164Pro Single submitter ⚠
- p.Glu54Asp Single submitter ⚠
- p.Glu71Gln Single submitter ⚠
- p.Glu90Lys Single submitter ⚠
- p.His106Arg Single submitter ⚠
- p.His126Arg Single submitter ⚠
- p.Ile14Val Single submitter ⚠
- p.Leu178Phe Single submitter ⚠
- p.Phe151Tyr Single submitter ⚠
- p.Thr141Met Single submitter ⚠
- p.Thr45Ile Single submitter ⚠
- p.Thr72Asn Single submitter ⚠
- p.Val19Met Single submitter ⚠