CDC26 — 11 ClinVar variants
All ClinVar germline CDC26 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 11 flagged for review →
11 Uncertain significance
Full CDC26 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 11
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 6
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CDC26 p.Glu27Gly Uncertain significance Single submitter
- CDC26 p.Ile48Val Uncertain significance Single submitter
- CDC26 p.Leu50Phe Uncertain significance Single submitter
- CDC26 p.Ser52Asn Uncertain significance Single submitter
- CDC26 p.Thr28Ala Uncertain significance Single submitter
- CDC26 p.Thr7Arg Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All CDC26 variants
Uncertain significance 11
- p.Arg29His Single submitter ⚠
- p.Arg29Ser Single submitter ⚠
- p.Glu27Gly Single submitter ⚠
- p.Ile16Thr Single submitter ⚠
- p.Ile48Val Single submitter ⚠
- p.Ile61Val Single submitter ⚠
- p.Leu50Phe Single submitter ⚠
- p.Ser52Asn Single submitter ⚠
- p.Ser78Cys Single submitter ⚠
- p.Thr28Ala Single submitter ⚠
- p.Thr7Arg Single submitter ⚠