CEACAM20 — 78 ClinVar variants
All ClinVar germline CEACAM20 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 76 flagged for review →
4 Likely benign · 74 Uncertain significance
Full CEACAM20 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 76
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 41
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CEACAM20 p.Ala143Thr Uncertain significance Single submitter
- CEACAM20 p.Ala4Thr Uncertain significance Single submitter
- CEACAM20 p.Arg353Lys Uncertain significance Single submitter
- CEACAM20 p.Arg427His Uncertain significance Single submitter
- CEACAM20 p.Arg63Lys Uncertain significance Single submitter
- CEACAM20 p.Asn473Lys Uncertain significance Single submitter
- CEACAM20 p.Asn473Ser Uncertain significance Single submitter
- CEACAM20 p.Asp132Gly Uncertain significance Single submitter
- CEACAM20 p.Gln281His Uncertain significance Single submitter
- CEACAM20 p.Gln286Arg Uncertain significance Single submitter
- CEACAM20 p.Glu354Gln Uncertain significance Single submitter
- CEACAM20 p.Gly13Ala Uncertain significance Single submitter
- CEACAM20 p.Gly182Val Uncertain significance Single submitter
- CEACAM20 p.Gly320Arg Uncertain significance Single submitter
- CEACAM20 p.Gly412Arg Uncertain significance Single submitter
- CEACAM20 p.Gly450Asp Uncertain significance Single submitter
- CEACAM20 p.His9Gln Uncertain significance Single submitter
- CEACAM20 p.Ile217Asn Uncertain significance Single submitter
- CEACAM20 p.Ile471Leu Uncertain significance Single submitter
- CEACAM20 p.Ile80Val Uncertain significance Single submitter
- CEACAM20 p.Ile99Asn Uncertain significance Single submitter
- CEACAM20 p.Leu338Pro Uncertain significance Single submitter
- CEACAM20 p.Leu371Arg Uncertain significance Single submitter
- CEACAM20 p.Lys118Glu Uncertain significance Single submitter
- CEACAM20 p.Lys434Thr Uncertain significance Single submitter
- CEACAM20 p.Met255Val Uncertain significance Single submitter
- CEACAM20 p.Met85Lys Uncertain significance Single submitter
- CEACAM20 p.Pro38Ala Uncertain significance Single submitter
- CEACAM20 p.Pro3Ser Uncertain significance Single submitter
- CEACAM20 p.Pro509Leu Uncertain significance Single submitter
- CEACAM20 p.Pro529Leu Uncertain significance Single submitter
- CEACAM20 p.Pro55Leu Uncertain significance Single submitter
- CEACAM20 p.Pro563Arg Uncertain significance Single submitter
- CEACAM20 p.Ser149Arg Uncertain significance Single submitter
- CEACAM20 p.Ser19Leu Uncertain significance Single submitter
- CEACAM20 p.Ser44Asn Uncertain significance Single submitter
- CEACAM20 p.Thr22Ile Uncertain significance Single submitter
- CEACAM20 p.Thr33Asn Uncertain significance Single submitter
- CEACAM20 p.Val177Ala Uncertain significance Single submitter
- CEACAM20 p.Val23Ile Uncertain significance Single submitter
- CEACAM20 p.Val433Gly Uncertain significance Single submitter
Predictors split 35
The independent predictors disagree with each other — read with care.
- CEACAM20 p.Ala189Val Likely benign Single submitter
- CEACAM20 p.Ala426Val Uncertain significance Single submitter
- CEACAM20 p.Arg113Cys Uncertain significance Single submitter
- CEACAM20 p.Arg148Lys Uncertain significance Single submitter
- CEACAM20 p.Arg316Gln Uncertain significance Single submitter
- CEACAM20 p.Arg332Gln Likely benign Single submitter
- CEACAM20 p.Arg334Trp Uncertain significance Single submitter
- CEACAM20 p.Asn513Thr Uncertain significance Single submitter
- CEACAM20 p.Asn573Ile Uncertain significance Single submitter
- CEACAM20 p.Asp119Asn Uncertain significance Single submitter
- CEACAM20 p.Asp150Asn Uncertain significance Single submitter
- CEACAM20 p.Glu181Gly Uncertain significance Single submitter
- CEACAM20 p.Glu378Lys Uncertain significance Single submitter
- CEACAM20 p.Gly291Cys Uncertain significance Single submitter
- CEACAM20 p.His100Pro Uncertain significance Single submitter
- CEACAM20 p.Ile451Val Uncertain significance Single submitter
- CEACAM20 p.Leu188Phe Uncertain significance Single submitter
- CEACAM20 p.Leu20Ile Uncertain significance Single submitter
- CEACAM20 p.Leu465Met Uncertain significance Single submitter
- CEACAM20 p.Lys69Gln Uncertain significance Single submitter
- CEACAM20 p.Pro196Ser Uncertain significance Single submitter
- CEACAM20 p.Pro556Leu Uncertain significance Single submitter
- CEACAM20 p.Ser209Phe Uncertain significance Single submitter
- CEACAM20 p.Ser335Gly Uncertain significance Single submitter
- CEACAM20 p.Thr186Asn Uncertain significance Single submitter
- CEACAM20 p.Thr191Ile Uncertain significance Single submitter
- CEACAM20 p.Thr216Ile Uncertain significance Single submitter
- CEACAM20 p.Thr275Asn Uncertain significance Single submitter
- CEACAM20 p.Thr308Ser Uncertain significance Single submitter
- CEACAM20 p.Thr319Ile Uncertain significance Single submitter
- CEACAM20 p.Tyr467Phe Uncertain significance Single submitter
- CEACAM20 p.Val232Leu Uncertain significance Single submitter
- CEACAM20 p.Val247Phe Uncertain significance Single submitter
- CEACAM20 p.Val259Met Uncertain significance Single submitter
- CEACAM20 p.Val285Ala Uncertain significance Single submitter
All CEACAM20 variants
Likely benign 4
- p.Ala189Val Single submitter ⚠
- p.Arg332Gln Single submitter ⚠
- p.Arg386His Single submitter
- p.Ile60Thr Single submitter
Uncertain significance 74
- p.Ala143Thr Single submitter ⚠
- p.Ala426Val Single submitter ⚠
- p.Ala4Thr Single submitter ⚠
- p.Arg113Cys Single submitter ⚠
- p.Arg148Lys Single submitter ⚠
- p.Arg316Gln Single submitter ⚠
- p.Arg334Trp Single submitter ⚠
- p.Arg353Lys Single submitter ⚠
- p.Arg427His Single submitter ⚠
- p.Arg63Lys Single submitter ⚠
- p.Asn473Lys Single submitter ⚠
- p.Asn473Ser Single submitter ⚠
- p.Asn513Thr Single submitter ⚠
- p.Asn573Ile Single submitter ⚠
- p.Asp119Asn Single submitter ⚠
- p.Asp132Gly Single submitter ⚠
- p.Asp150Asn Single submitter ⚠
- p.Gln281His Single submitter ⚠
- p.Gln286Arg Single submitter ⚠
- p.Glu181Gly Single submitter ⚠
- p.Glu354Gln Single submitter ⚠
- p.Glu378Lys Single submitter ⚠
- p.Gly13Ala Single submitter ⚠
- p.Gly182Val Single submitter ⚠
- p.Gly291Cys Single submitter ⚠
- p.Gly320Arg Single submitter ⚠
- p.Gly412Arg Single submitter ⚠
- p.Gly450Asp Single submitter ⚠
- p.His100Pro Single submitter ⚠
- p.His9Gln Single submitter ⚠
- p.Ile217Asn Single submitter ⚠
- p.Ile451Val Single submitter ⚠
- p.Ile471Leu Single submitter ⚠
- p.Ile80Val Single submitter ⚠
- p.Ile99Asn Single submitter ⚠
- p.Leu188Phe Single submitter ⚠
- p.Leu20Ile Single submitter ⚠
- p.Leu338Pro Single submitter ⚠
- p.Leu371Arg Single submitter ⚠
- p.Leu465Met Single submitter ⚠
- p.Lys118Glu Single submitter ⚠
- p.Lys434Thr Single submitter ⚠
- p.Lys69Gln Single submitter ⚠
- p.Met255Val Single submitter ⚠
- p.Met85Lys Single submitter ⚠
- p.Pro196Ser Single submitter ⚠
- p.Pro38Ala Single submitter ⚠
- p.Pro3Ser Single submitter ⚠
- p.Pro509Leu Single submitter ⚠
- p.Pro529Leu Single submitter ⚠
- p.Pro556Leu Single submitter ⚠
- p.Pro55Leu Single submitter ⚠
- p.Pro563Arg Single submitter ⚠
- p.Ser149Arg Single submitter ⚠
- p.Ser19Leu Single submitter ⚠
- p.Ser209Phe Single submitter ⚠
- p.Ser335Gly Single submitter ⚠
- p.Ser44Asn Single submitter ⚠
- p.Thr186Asn Single submitter ⚠
- p.Thr191Ile Single submitter ⚠
- p.Thr216Ile Single submitter ⚠
- p.Thr22Ile Single submitter ⚠
- p.Thr275Asn Single submitter ⚠
- p.Thr308Ser Single submitter ⚠
- p.Thr319Ile Single submitter ⚠
- p.Thr33Asn Single submitter ⚠
- p.Tyr467Phe Single submitter ⚠
- p.Val177Ala Single submitter ⚠
- p.Val232Leu Single submitter ⚠
- p.Val23Ile Single submitter ⚠
- p.Val247Phe Single submitter ⚠
- p.Val259Met Single submitter ⚠
- p.Val285Ala Single submitter ⚠
- p.Val433Gly Single submitter ⚠