CEBPB — 50 ClinVar variants
All ClinVar germline CEBPB variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 47 flagged for review →
3 Likely benign · 47 Uncertain significance
Full CEBPB gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 47
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 21
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CEBPB p.Ala147Pro Uncertain significance Single submitter
- CEBPB p.Ala241Val Uncertain significance Single submitter
- CEBPB p.Ala39Pro Uncertain significance Single submitter
- CEBPB p.Arg322Leu Uncertain significance Single submitter
- CEBPB p.Arg53Ser Uncertain significance Single submitter
- CEBPB p.Asn130Ser Uncertain significance Single submitter
- CEBPB p.Asp124Glu Uncertain significance Single submitter
- CEBPB p.Asp125Asn Uncertain significance Single submitter
- CEBPB p.Asp95Ala Uncertain significance Single submitter
- CEBPB p.Gln86His Uncertain significance Single submitter
- CEBPB p.Glu180Gln Uncertain significance Single submitter
- CEBPB p.Glu273Ala Uncertain significance Single submitter
- CEBPB p.Glu298Gly Uncertain significance Single submitter
- CEBPB p.Glu336Asp Uncertain significance Single submitter
- CEBPB p.Ile276Leu Uncertain significance Single submitter
- CEBPB p.Pro193Ala Uncertain significance Single submitter
- CEBPB p.Pro193Arg Uncertain significance Single submitter
- CEBPB p.Pro254Arg Uncertain significance Single submitter
- CEBPB p.Pro59Ala Uncertain significance Single submitter
- CEBPB p.Thr92Arg Uncertain significance Single submitter
- CEBPB p.Tyr30Phe Uncertain significance Single submitter
Predictors split 26
The independent predictors disagree with each other — read with care.
- CEBPB p.Ala103Thr Uncertain significance Single submitter
- CEBPB p.Ala103Val Uncertain significance Single submitter
- CEBPB p.Ala247Val Uncertain significance Single submitter
- CEBPB p.Ala250Val Uncertain significance Single submitter
- CEBPB p.Ala253Thr Uncertain significance Single submitter
- CEBPB p.Ala39Thr Uncertain significance Single submitter
- CEBPB p.Asp125Gly Uncertain significance Single submitter
- CEBPB p.Asp272Asn Uncertain significance Single submitter
- CEBPB p.Gly143Trp Uncertain significance Single submitter
- CEBPB p.Gly251Glu Uncertain significance Single submitter
- CEBPB p.Leu224Arg Uncertain significance Single submitter
- CEBPB p.Leu297Val Uncertain significance Single submitter
- CEBPB p.Pro106His Uncertain significance Single submitter
- CEBPB p.Pro15Ser Uncertain significance Single submitter
- CEBPB p.Pro165Ala Uncertain significance Single submitter
- CEBPB p.Pro169Leu Uncertain significance Single submitter
- CEBPB p.Pro169Ser Uncertain significance Single submitter
- CEBPB p.Pro238Ser Uncertain significance Single submitter
- CEBPB p.Pro337Arg Uncertain significance Single submitter
- CEBPB p.Pro49Leu Uncertain significance Single submitter
- CEBPB p.Pro54Arg Uncertain significance Single submitter
- CEBPB p.Pro54Leu Uncertain significance Single submitter
- CEBPB p.Pro59Thr Uncertain significance Single submitter
- CEBPB p.Ser325Asn Uncertain significance Single submitter
- CEBPB p.Val140Met Uncertain significance Single submitter
- CEBPB p.Val267Ala Uncertain significance Single submitter
All CEBPB variants
Likely benign 3
- p.Ala255Pro Single submitter
- p.Pro15= Single submitter
- p.Asn282del No assertion criteria EBV-positive nodal T- and NK-cell lymphoma
Uncertain significance 47
- p.Ala103Thr Single submitter ⚠
- p.Ala103Val Single submitter ⚠
- p.Ala147Pro Single submitter ⚠
- p.Ala241Val Single submitter ⚠
- p.Ala247Val Single submitter ⚠
- p.Ala250Val Single submitter ⚠
- p.Ala253Thr Single submitter ⚠
- p.Ala39Pro Single submitter ⚠
- p.Ala39Thr Single submitter ⚠
- p.Arg322Leu Single submitter ⚠
- p.Arg53Ser Single submitter ⚠
- p.Asn130Ser Single submitter ⚠
- p.Asp124Glu Single submitter ⚠
- p.Asp125Asn Single submitter ⚠
- p.Asp125Gly Single submitter ⚠
- p.Asp272Asn Single submitter ⚠
- p.Asp95Ala Single submitter ⚠
- p.Gln86His Single submitter ⚠
- p.Glu180Gln Single submitter ⚠
- p.Glu273Ala Single submitter ⚠
- p.Glu298Gly Single submitter ⚠
- p.Glu336Asp Single submitter ⚠
- p.Gly143Trp Single submitter ⚠
- p.Gly251Glu Single submitter ⚠
- p.Ile276Leu Single submitter ⚠
- p.Leu224Arg Single submitter ⚠
- p.Leu297Val Single submitter ⚠
- p.Pro106His Single submitter ⚠
- p.Pro15Ser Single submitter ⚠
- p.Pro165Ala Single submitter ⚠
- p.Pro169Leu Single submitter ⚠
- p.Pro169Ser Single submitter ⚠
- p.Pro193Ala Single submitter ⚠
- p.Pro193Arg Single submitter ⚠
- p.Pro238Ser Single submitter ⚠
- p.Pro254Arg Single submitter ⚠
- p.Pro337Arg Single submitter ⚠
- p.Pro49Leu Single submitter ⚠
- p.Pro54Arg Single submitter ⚠
- p.Pro54Leu Single submitter ⚠
- p.Pro59Ala Single submitter ⚠
- p.Pro59Thr Single submitter ⚠
- p.Ser325Asn Single submitter ⚠
- p.Thr92Arg Single submitter ⚠
- p.Tyr30Phe Single submitter ⚠
- p.Val140Met Single submitter ⚠
- p.Val267Ala Single submitter ⚠