CFAP107 — 3 ClinVar variants
All ClinVar germline CFAP107 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 3 flagged for review →
3 Uncertain significance
Full CFAP107 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 3
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 2
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All CFAP107 variants
Uncertain significance 3
- p.Ala180Val Single submitter ⚠
- p.Arg115Cys Single submitter ⚠
- p.Asn139Ser Single submitter ⚠