CFAP184 — 96 ClinVar variants
All ClinVar germline CFAP184 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 93 flagged for review →
3 Likely benign · 93 Uncertain significance
Full CFAP184 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 93
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 41
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CFAP184 p.Ala142Val Uncertain significance Single submitter
- CFAP184 p.Ala160Thr Uncertain significance Single submitter
- CFAP184 p.Ala533Thr Uncertain significance Single submitter
- CFAP184 p.Arg139Gly Uncertain significance Single submitter
- CFAP184 p.Arg164Leu Uncertain significance Single submitter
- CFAP184 p.Arg185Lys Uncertain significance Single submitter
- CFAP184 p.Arg24Gln Uncertain significance Single submitter
- CFAP184 p.Arg329His Uncertain significance Single submitter
- CFAP184 p.Arg356Gln Uncertain significance Single submitter
- CFAP184 p.Arg376Leu Uncertain significance Single submitter
- CFAP184 p.Asn496Ser Uncertain significance Single submitter
- CFAP184 p.Asp407Gly Uncertain significance Single submitter
- CFAP184 p.Cys459Arg Uncertain significance Single submitter
- CFAP184 p.Glu159Gly Uncertain significance Single submitter
- CFAP184 p.Glu214Asp Uncertain significance Single submitter
- CFAP184 p.Glu267Asp Uncertain significance Single submitter
- CFAP184 p.Gly198Arg Uncertain significance Single submitter
- CFAP184 p.Gly343Ser Uncertain significance Single submitter
- CFAP184 p.Gly60Ser Uncertain significance Single submitter
- CFAP184 p.Gly80Ala Uncertain significance Single submitter
- CFAP184 p.Gly83Glu Uncertain significance Single submitter
- CFAP184 p.His7Arg Uncertain significance Single submitter
- CFAP184 p.Ile253Leu Uncertain significance Single submitter
- CFAP184 p.Ile28Thr Uncertain significance Single submitter
- CFAP184 p.Ile477Asn Uncertain significance Single submitter
- CFAP184 p.Leu478Arg Uncertain significance Single submitter
- CFAP184 p.Leu507Phe Uncertain significance Single submitter
- CFAP184 p.Lys218Glu Uncertain significance Single submitter
- CFAP184 p.Pro117Thr Uncertain significance Single submitter
- CFAP184 p.Pro25Ser Uncertain significance Single submitter
- CFAP184 p.Pro38Arg Uncertain significance Single submitter
- CFAP184 p.Pro70Arg Uncertain significance Single submitter
- CFAP184 p.Ser182Asn Uncertain significance Single submitter
- CFAP184 p.Thr175Arg Uncertain significance Single submitter
- CFAP184 p.Thr490Met Uncertain significance Single submitter
- CFAP184 p.Tyr202His Uncertain significance Single submitter
- CFAP184 p.Val268Leu Uncertain significance Single submitter
- CFAP184 p.Val323Met Uncertain significance Single submitter
- CFAP184 p.Val375Leu Uncertain significance Single submitter
- CFAP184 p.Val375Met Uncertain significance Single submitter
- CFAP184 p.Val542Met Uncertain significance Single submitter
Predictors split 52
The independent predictors disagree with each other — read with care.
- CFAP184 p.Ala105Thr Uncertain significance Single submitter
- CFAP184 p.Ala109Asp Uncertain significance Single submitter
- CFAP184 p.Ala126Thr Uncertain significance Single submitter
- CFAP184 p.Ala126Val Uncertain significance Single submitter
- CFAP184 p.Ala275Ser Uncertain significance Single submitter
- CFAP184 p.Ala374Pro Uncertain significance Single submitter
- CFAP184 p.Ala469Val Uncertain significance Single submitter
- CFAP184 p.Ala62Thr Uncertain significance Single submitter
- CFAP184 p.Ala78Ser Uncertain significance Single submitter
- CFAP184 p.Arg271Trp Uncertain significance Single submitter
- CFAP184 p.Arg433His Uncertain significance Single submitter
- CFAP184 p.Arg509Gly Uncertain significance Single submitter
- CFAP184 p.Arg509Pro Uncertain significance Single submitter
- CFAP184 p.Arg509Trp Uncertain significance Single submitter
- CFAP184 p.Arg543Thr Uncertain significance Single submitter
- CFAP184 p.Asp186Asn Uncertain significance Single submitter
- CFAP184 p.Asp205His Uncertain significance Single submitter
- CFAP184 p.Asp301Tyr Uncertain significance Single submitter
- CFAP184 p.Asp366Asn Uncertain significance Single submitter
- CFAP184 p.Asp491Ala Uncertain significance Single submitter
- CFAP184 p.Asp510Glu Uncertain significance Single submitter
- CFAP184 p.Cys499Tyr Uncertain significance Single submitter
- CFAP184 p.Gln58His Uncertain significance Single submitter
- CFAP184 p.Gln66His Uncertain significance Single submitter
- CFAP184 p.Glu102Asp Uncertain significance Single submitter
- CFAP184 p.Glu107Asp Uncertain significance Single submitter
- CFAP184 p.Glu121Gln Uncertain significance Single submitter
- CFAP184 p.Glu168Lys Uncertain significance Single submitter
- CFAP184 p.Glu169Asp Uncertain significance Single submitter
- CFAP184 p.Glu173Lys Uncertain significance Single submitter
- CFAP184 p.Glu279Gln Uncertain significance Single submitter
- CFAP184 p.Glu369Asp Uncertain significance Single submitter
- CFAP184 p.Glu371Val Uncertain significance Single submitter
- CFAP184 p.Glu420Asp Uncertain significance Single submitter
- CFAP184 p.Glu44Lys Uncertain significance Single submitter
- CFAP184 p.Glu48Gln Uncertain significance Single submitter
- CFAP184 p.Gly262Ser Uncertain significance Single submitter
- CFAP184 p.Gly349Ala Uncertain significance Single submitter
- CFAP184 p.Gly350Trp Uncertain significance Single submitter
- CFAP184 p.Gly503Ser Uncertain significance Single submitter
- CFAP184 p.His251Pro Uncertain significance Single submitter
- CFAP184 p.Ile406Thr Uncertain significance Single submitter
- CFAP184 p.Leu228Phe Uncertain significance Single submitter
- CFAP184 p.Lys183Asn Uncertain significance Single submitter
- CFAP184 p.Lys383Asn Uncertain significance Single submitter
- CFAP184 p.Lys482Gln Uncertain significance Single submitter
- CFAP184 p.Met342Ile Uncertain significance Single submitter
- CFAP184 p.Phe389Leu Uncertain significance Single submitter
- CFAP184 p.Pro90Gln Uncertain significance Single submitter
- CFAP184 p.Ser5Phe Uncertain significance Single submitter
- CFAP184 p.Thr481Met Uncertain significance Single submitter
- CFAP184 p.Val446Gly Uncertain significance Single submitter
All CFAP184 variants
Likely benign 3
- p.Arg494Lys Single submitter
- p.Gln303Glu Single submitter
- p.Gly179Ser Single submitter
Uncertain significance 93
- p.Ala105Thr Single submitter ⚠
- p.Ala109Asp Single submitter ⚠
- p.Ala126Thr Single submitter ⚠
- p.Ala126Val Single submitter ⚠
- p.Ala142Val Single submitter ⚠
- p.Ala160Thr Single submitter ⚠
- p.Ala275Ser Single submitter ⚠
- p.Ala374Pro Single submitter ⚠
- p.Ala469Val Single submitter ⚠
- p.Ala533Thr Single submitter ⚠
- p.Ala62Thr Single submitter ⚠
- p.Ala78Ser Single submitter ⚠
- p.Arg139Gly Single submitter ⚠
- p.Arg164Leu Single submitter ⚠
- p.Arg185Lys Single submitter ⚠
- p.Arg24Gln Single submitter ⚠
- p.Arg271Trp Single submitter ⚠
- p.Arg329His Single submitter ⚠
- p.Arg356Gln Single submitter ⚠
- p.Arg376Leu Single submitter ⚠
- p.Arg433His Single submitter ⚠
- p.Arg509Gly Single submitter ⚠
- p.Arg509Pro Single submitter ⚠
- p.Arg509Trp Single submitter ⚠
- p.Arg543Thr Single submitter ⚠
- p.Asn496Ser Single submitter ⚠
- p.Asp186Asn Single submitter ⚠
- p.Asp205His Single submitter ⚠
- p.Asp301Tyr Single submitter ⚠
- p.Asp366Asn Single submitter ⚠
- p.Asp407Gly Single submitter ⚠
- p.Asp491Ala Single submitter ⚠
- p.Asp510Glu Single submitter ⚠
- p.Cys459Arg Single submitter ⚠
- p.Cys499Tyr Single submitter ⚠
- p.Gln58His Single submitter ⚠
- p.Gln66His Single submitter ⚠
- p.Glu102Asp Single submitter ⚠
- p.Glu107Asp Single submitter ⚠
- p.Glu121Gln Single submitter ⚠
- p.Glu159Gly Single submitter ⚠
- p.Glu168Lys Single submitter ⚠
- p.Glu169Asp Single submitter ⚠
- p.Glu173Lys Single submitter ⚠
- p.Glu214Asp Single submitter ⚠
- p.Glu267Asp Single submitter ⚠
- p.Glu279Gln Single submitter ⚠
- p.Glu369Asp Single submitter ⚠
- p.Glu371Val Single submitter ⚠
- p.Glu420Asp Single submitter ⚠
- p.Glu44Lys Single submitter ⚠
- p.Glu48Gln Single submitter ⚠
- p.Gly198Arg Single submitter ⚠
- p.Gly262Ser Single submitter ⚠
- p.Gly343Ser Single submitter ⚠
- p.Gly349Ala Single submitter ⚠
- p.Gly350Trp Single submitter ⚠
- p.Gly503Ser Single submitter ⚠
- p.Gly60Ser Single submitter ⚠
- p.Gly80Ala Single submitter ⚠
- p.Gly83Glu Single submitter ⚠
- p.His251Pro Single submitter ⚠
- p.His7Arg Single submitter ⚠
- p.Ile253Leu Single submitter ⚠
- p.Ile28Thr Single submitter ⚠
- p.Ile406Thr Single submitter ⚠
- p.Ile477Asn Single submitter ⚠
- p.Leu228Phe Single submitter ⚠
- p.Leu478Arg Single submitter ⚠
- p.Leu507Phe Single submitter ⚠
- p.Lys183Asn Single submitter ⚠
- p.Lys218Glu Single submitter ⚠
- p.Lys383Asn Single submitter ⚠
- p.Lys482Gln Single submitter ⚠
- p.Met342Ile Single submitter ⚠
- p.Phe389Leu Single submitter ⚠
- p.Pro117Thr Single submitter ⚠
- p.Pro25Ser Single submitter ⚠
- p.Pro38Arg Single submitter ⚠
- p.Pro70Arg Single submitter ⚠
- p.Pro90Gln Single submitter ⚠
- p.Ser182Asn Single submitter ⚠
- p.Ser5Phe Single submitter ⚠
- p.Thr175Arg Single submitter ⚠
- p.Thr481Met Single submitter ⚠
- p.Thr490Met Single submitter ⚠
- p.Tyr202His Single submitter ⚠
- p.Val268Leu Single submitter ⚠
- p.Val323Met Single submitter ⚠
- p.Val375Leu Single submitter ⚠
- p.Val375Met Single submitter ⚠
- p.Val446Gly Single submitter ⚠
- p.Val542Met Single submitter ⚠