CHLSN — 3 ClinVar variants
All ClinVar germline CHLSN variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 2 flagged for review →
1 Likely benign · 2 Uncertain significance
Full CHLSN gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 2
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 2
The independent predictors disagree with each other — read with care.
All CHLSN variants
Likely benign 1
- c.405+3G>A Single submitter
Uncertain significance 2
- p.Leu70Val Single submitter ⚠
- p.Thr121Met Single submitter ⚠