COL15A1 — 287 ClinVar variants
All ClinVar germline COL15A1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 237 flagged for review →
34 Benign · 38 Likely benign · 215 Uncertain significance
Full COL15A1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 237
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 115
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- COL15A1 p.Ala1006Ser Uncertain significance Single submitter
- COL15A1 p.Ala1193Val Uncertain significance Single submitter
- COL15A1 p.Ala1244Ser Uncertain significance Single submitter
- COL15A1 p.Ala1348Gly Uncertain significance Single submitter
- COL15A1 p.Ala1386Thr Uncertain significance Single submitter
- COL15A1 p.Ala345Ser Uncertain significance Single submitter
- COL15A1 p.Ala345Thr Uncertain significance Single submitter
- COL15A1 p.Ala420Thr Uncertain significance Single submitter
- COL15A1 p.Ala498Thr Uncertain significance Single submitter
- COL15A1 p.Ala761Val Uncertain significance Single submitter
- COL15A1 p.Ala79Ser Uncertain significance Single submitter
- COL15A1 p.Ala948Gly Uncertain significance Single submitter
- COL15A1 p.Arg1168Cys Uncertain significance Single submitter
- COL15A1 p.Arg1333Cys Uncertain significance Single submitter
- COL15A1 p.Arg1333Pro Uncertain significance Single submitter
- COL15A1 p.Arg1372Gln Uncertain significance Single submitter
- COL15A1 p.Arg876Met Uncertain significance Single submitter
- COL15A1 p.Arg913Cys Uncertain significance Single submitter
- COL15A1 p.Arg962Gln Uncertain significance Single submitter
- COL15A1 p.Asn1030Lys Uncertain significance Single submitter
- COL15A1 p.Asn393Tyr Uncertain significance Single submitter
- COL15A1 p.Asp112Gly Uncertain significance Single submitter
- COL15A1 p.Asp1142Gly Uncertain significance Single submitter
- COL15A1 p.Asp1187Asn Uncertain significance Single submitter
- COL15A1 p.Cys179Tyr Uncertain significance Single submitter
- COL15A1 p.Gln1075Arg Uncertain significance Single submitter
- COL15A1 p.Gln38Pro Uncertain significance Single submitter
- COL15A1 p.Gln45Lys Uncertain significance Single submitter
- COL15A1 p.Gln560Lys Uncertain significance Single submitter
- COL15A1 p.Gln710Pro Uncertain significance Single submitter
- COL15A1 p.Gln749Lys Uncertain significance Single submitter
- COL15A1 p.Glu213Lys Uncertain significance Single submitter
- COL15A1 p.Glu239Asp Uncertain significance Single submitter
- COL15A1 p.Glu291Asp Uncertain significance Single submitter
- COL15A1 p.Glu573Gln Uncertain significance Single submitter
- COL15A1 p.Glu820Val Uncertain significance Single submitter
- COL15A1 p.Gly1093Arg Uncertain significance Single submitter
- COL15A1 p.Gly1105Glu Uncertain significance Single submitter
- COL15A1 p.Gly1154Arg Uncertain significance Single submitter
- COL15A1 p.Gly1172Asp Uncertain significance Single submitter
- COL15A1 p.Gly1293Asp Uncertain significance Single submitter
- COL15A1 p.Gly527Ser Uncertain significance Single submitter
- COL15A1 p.Gly571Ala Uncertain significance Single submitter
- COL15A1 p.Gly600Ser Uncertain significance Single submitter
- COL15A1 p.Gly625Arg Uncertain significance Single submitter
- COL15A1 p.Gly631Arg Uncertain significance Single submitter
- COL15A1 p.Gly664Glu Uncertain significance Single submitter
- COL15A1 p.Gly709Arg Uncertain significance Single submitter
- COL15A1 p.Gly727Glu Uncertain significance Single submitter
- COL15A1 p.Gly773Glu Uncertain significance Single submitter
- COL15A1 p.Gly835Glu Uncertain significance Single submitter
- COL15A1 p.Gly924Glu Uncertain significance Single submitter
- COL15A1 p.Gly987Arg Uncertain significance Single submitter
- COL15A1 p.His1021Asp Uncertain significance Single submitter
- COL15A1 p.His1257Arg Uncertain significance Single submitter
- COL15A1 p.His144Gln Uncertain significance Single submitter
- COL15A1 p.His331Tyr Uncertain significance Single submitter
- COL15A1 p.His797Leu Uncertain significance Single submitter
- COL15A1 p.His810Gln Uncertain significance Single submitter
- COL15A1 p.His810Tyr Uncertain significance Single submitter
- COL15A1 p.His901Pro Uncertain significance Single submitter
- COL15A1 p.Ile1184Leu Uncertain significance Single submitter
- COL15A1 p.Ile258Met Uncertain significance Single submitter
- COL15A1 p.Ile338Val Uncertain significance Single submitter
- COL15A1 p.Ile93Val Uncertain significance Single submitter
- COL15A1 p.Leu1134Val Uncertain significance Single submitter
- COL15A1 p.Leu574Phe Uncertain significance Single submitter
- COL15A1 p.Leu801Phe Uncertain significance Single submitter
- COL15A1 p.Lys1147Asn Uncertain significance Single submitter
- COL15A1 p.Lys1279Arg Uncertain significance Single submitter
- COL15A1 p.Lys1360Arg Uncertain significance Single submitter
- COL15A1 p.Lys635Arg Uncertain significance Single submitter
- COL15A1 p.Lys635Asn Uncertain significance Single submitter
- COL15A1 p.Lys755Glu Uncertain significance Single submitter
- COL15A1 p.Lys799Asn Uncertain significance Single submitter
- COL15A1 p.Lys896Arg Uncertain significance Single submitter
- COL15A1 p.Met1225Val Uncertain significance Single submitter
- COL15A1 p.Met1383Ile Uncertain significance Single submitter
- COL15A1 p.Met157Arg Uncertain significance Single submitter
- COL15A1 p.Met204Ile Uncertain significance Single submitter
- COL15A1 p.Met290Ile Uncertain significance Single submitter
- COL15A1 p.Met389Thr Uncertain significance Single submitter
- COL15A1 p.Met780Leu Uncertain significance Single submitter
- COL15A1 p.Met813Leu Uncertain significance Single submitter
- COL15A1 p.Met886Ile Uncertain significance Single submitter
- COL15A1 p.Met930Val Uncertain significance Single submitter
- COL15A1 p.Pro1191Leu Uncertain significance Single submitter
- COL15A1 p.Pro226His Uncertain significance Single submitter
- COL15A1 p.Pro269Thr Uncertain significance Single submitter
- COL15A1 p.Pro286Ser Uncertain significance Single submitter
- COL15A1 p.Pro535Leu Uncertain significance Single submitter
- COL15A1 p.Pro549Ser Uncertain significance Single submitter
- COL15A1 p.Pro575Ser Uncertain significance Single submitter
- COL15A1 p.Pro580Leu Uncertain significance Single submitter
- COL15A1 p.Pro583Leu Uncertain significance Single submitter
- COL15A1 p.Pro653Leu Uncertain significance Single submitter
- COL15A1 p.Pro759Thr Uncertain significance Single submitter
- COL15A1 p.Pro884Arg Uncertain significance Single submitter
- COL15A1 p.Ser101Thr Uncertain significance Single submitter
- COL15A1 p.Ser241Leu Uncertain significance Single submitter
- COL15A1 p.Ser343Pro Uncertain significance Single submitter
- COL15A1 p.Ser601Trp Uncertain significance Single submitter
- COL15A1 p.Ser757Pro Uncertain significance Single submitter
- COL15A1 p.Ser997Leu Uncertain significance Single submitter
- COL15A1 p.Thr246Ser Uncertain significance Single submitter
- COL15A1 p.Thr282Ala Uncertain significance Single submitter
- COL15A1 p.Thr33Arg Uncertain significance Single submitter
- COL15A1 p.Thr672Ala Uncertain significance Single submitter
- COL15A1 p.Thr760Met Uncertain significance Single submitter
- COL15A1 p.Tyr67His Uncertain significance Single submitter
- COL15A1 p.Val156Leu Uncertain significance Single submitter
- COL15A1 p.Val262Ile Uncertain significance Single submitter
- COL15A1 p.Val330Leu Uncertain significance Single submitter
- COL15A1 p.Val541Met Uncertain significance Single submitter
- COL15A1 p.Val800Ile Uncertain significance Single submitter
Predictors split 122
The independent predictors disagree with each other — read with care.
- COL15A1 p.Pro1063Leu Benign Multiple submitters
- COL15A1 p.Ala1115Val Uncertain significance Single submitter
- COL15A1 p.Ala1148Thr Uncertain significance Single submitter
- COL15A1 p.Ala413Thr Uncertain significance Single submitter
- COL15A1 p.Ala413Val Uncertain significance Single submitter
- COL15A1 p.Ala494Val Uncertain significance Single submitter
- COL15A1 p.Ala73Thr Uncertain significance Single submitter
- COL15A1 p.Ala92Val Uncertain significance Single submitter
- COL15A1 p.Arg133Gln Uncertain significance Single submitter
- COL15A1 p.Arg497Trp Uncertain significance Single submitter
- COL15A1 p.Arg618Lys Uncertain significance Single submitter
- COL15A1 p.Arg684Lys Uncertain significance Single submitter
- COL15A1 p.Arg913His Uncertain significance Single submitter
- COL15A1 p.Arg913Ser Uncertain significance Single submitter
- COL15A1 p.Asn1140His Uncertain significance Single submitter
- COL15A1 p.Asn1371Lys Uncertain significance Single submitter
- COL15A1 p.Asp1032Asn Uncertain significance Single submitter
- COL15A1 p.Asp1336Gly Uncertain significance Single submitter
- COL15A1 p.Asp484His Uncertain significance Single submitter
- COL15A1 p.Glu1000Lys Uncertain significance Single submitter
- COL15A1 p.Glu197Gly Uncertain significance Single submitter
- COL15A1 p.Glu251Lys Uncertain significance Single submitter
- COL15A1 p.Glu366Ala Uncertain significance Single submitter
- COL15A1 p.Glu366Lys Uncertain significance Single submitter
- COL15A1 p.Glu376Lys Uncertain significance Single submitter
- COL15A1 p.Glu496Lys Uncertain significance Single submitter
- COL15A1 p.Glu740Lys Uncertain significance Single submitter
- COL15A1 p.Glu860Lys Uncertain significance Single submitter
- COL15A1 p.Gly1034Arg Uncertain significance Single submitter
- COL15A1 p.Gly1047Cys Uncertain significance Single submitter
- COL15A1 p.Gly104Asp Uncertain significance Single submitter
- COL15A1 p.Gly1130Arg Uncertain significance Single submitter
- COL15A1 p.Gly1309Ser Uncertain significance Single submitter
- COL15A1 p.Gly31Cys Uncertain significance Single submitter
- COL15A1 p.Gly434Arg Uncertain significance Single submitter
- COL15A1 p.Gly48Ser Uncertain significance Single submitter
- COL15A1 p.Gly523Ser Uncertain significance Single submitter
- COL15A1 p.Gly594Val Uncertain significance Single submitter
- COL15A1 p.Gly604Ser Likely benign Single submitter
- COL15A1 p.Gly697Ser Uncertain significance Single submitter
- COL15A1 p.Gly70Arg Uncertain significance Single submitter
- COL15A1 p.Gly829Arg Uncertain significance Single submitter
- COL15A1 p.Gly927Glu Uncertain significance Single submitter
- COL15A1 p.Gly932Val Uncertain significance Single submitter
- COL15A1 p.Gly993Ser Uncertain significance Single submitter
- COL15A1 p.His1149Leu Uncertain significance Single submitter
- COL15A1 p.Ile1304Met Likely benign Single submitter
- COL15A1 p.Ile1323Thr Uncertain significance Single submitter
- COL15A1 p.Ile785Thr Likely benign Single submitter
- COL15A1 p.Leu1362Val Uncertain significance Single submitter
- COL15A1 p.Leu219Phe Uncertain significance Single submitter
- COL15A1 p.Leu259Phe Uncertain significance Single submitter
- COL15A1 p.Leu919Phe Uncertain significance Single submitter
- COL15A1 p.Lys681Met Uncertain significance Single submitter
- COL15A1 p.Met1313Ile Uncertain significance Single submitter
- COL15A1 p.Met1313Val Uncertain significance Single submitter
- COL15A1 p.Met440Ile Uncertain significance Single submitter
- COL15A1 p.Phe815Cys Uncertain significance Single submitter
- COL15A1 p.Phe87Leu Uncertain significance Single submitter
- COL15A1 p.Phe88Cys Uncertain significance Single submitter
- COL15A1 p.Pro1009Gln Uncertain significance Single submitter
- COL15A1 p.Pro1087Leu Uncertain significance Single submitter
- COL15A1 p.Pro1119His Uncertain significance Single submitter
- COL15A1 p.Pro1191His Uncertain significance Single submitter
- COL15A1 p.Pro1355Arg Uncertain significance Single submitter
- COL15A1 p.Pro22Arg Uncertain significance Single submitter
- COL15A1 p.Pro402Thr Uncertain significance Single submitter
- COL15A1 p.Pro482His Uncertain significance Single submitter
- COL15A1 p.Pro577Arg Uncertain significance Single submitter
- COL15A1 p.Pro621Thr Uncertain significance Single submitter
- COL15A1 p.Pro623Ser Uncertain significance Single submitter
- COL15A1 p.Pro660Leu Benign Single submitter
- COL15A1 p.Pro675Ser Uncertain significance Single submitter
- COL15A1 p.Pro702Ser Uncertain significance Single submitter
- COL15A1 p.Pro705Leu Benign Single submitter
- COL15A1 p.Pro719Leu Uncertain significance Single submitter
- COL15A1 p.Pro719Ser Uncertain significance Single submitter
- COL15A1 p.Pro725Ser Uncertain significance Single submitter
- COL15A1 p.Pro791Ala Uncertain significance Single submitter
- COL15A1 p.Pro791Leu Uncertain significance Single submitter
- COL15A1 p.Pro825Leu Uncertain significance Single submitter
- COL15A1 p.Pro849Ser Uncertain significance Single submitter
- COL15A1 p.Pro864Leu Uncertain significance Single submitter
- COL15A1 p.Pro884Thr Uncertain significance Single submitter
- COL15A1 p.Pro895Ser Uncertain significance Single submitter
- COL15A1 p.Pro943Ala Uncertain significance Single submitter
- COL15A1 p.Ser1248Tyr Uncertain significance Single submitter
- COL15A1 p.Ser1368Gly Uncertain significance Single submitter
- COL15A1 p.Ser332Cys Uncertain significance Single submitter
- COL15A1 p.Ser370Asn Uncertain significance Single submitter
- COL15A1 p.Ser479Ile Uncertain significance Single submitter
- COL15A1 p.Ser647Cys Uncertain significance Single submitter
- COL15A1 p.Ser816Leu Uncertain significance Single submitter
- COL15A1 p.Ser94Asn Uncertain significance Single submitter
- COL15A1 p.Thr1358Met Uncertain significance Single submitter
- COL15A1 p.Thr139Met Uncertain significance Single submitter
- COL15A1 p.Thr265Ile Uncertain significance Single submitter
- COL15A1 p.Thr33Ile Uncertain significance Single submitter
- COL15A1 p.Thr360Ile Uncertain significance Single submitter
- COL15A1 p.Thr360Pro Uncertain significance Single submitter
- COL15A1 p.Thr371Ala Uncertain significance Single submitter
- COL15A1 p.Thr391Met Benign Single submitter
- COL15A1 p.Thr44Met Uncertain significance Single submitter
- COL15A1 p.Thr461Ile Uncertain significance Single submitter
- COL15A1 p.Thr587Met Uncertain significance Single submitter
- COL15A1 p.Val154Gly Uncertain significance Single submitter
- COL15A1 p.Val431Met Uncertain significance Single submitter
-
COL15A1 p.Ala1148Val
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Arg163His
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Glu417Lys
Likely benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Glu506Asp
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Gly446Arg
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Gly504Val
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Gly984Ala
Likely benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Lys1001Arg
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Lys989Arg
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Phe851Leu
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Pro645Ser
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Pro660Gln
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Pro714Ser
Likely benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Val224Met
Benign
No assertion criteria
COL15A1-related disorder
-
COL15A1 p.Val96Met
Likely benign
No assertion criteria
COL15A1-related disorder
All COL15A1 variants
Benign 34
- p.Leu756= Multiple submitters
- p.Pro1063Leu Multiple submitters ⚠
- p.Ser218= Multiple submitters
- p.Pro660Leu Single submitter ⚠
- p.Pro705Leu Single submitter ⚠
- p.Thr391Met Single submitter ⚠
- c.1761+6A>G No assertion criteria COL15A1-related disorder
- c.1762-6T>C No assertion criteria COL15A1-related disorder
- c.952+9G>A No assertion criteria COL15A1-related disorder
- p.Ala1148Val No assertion criteria COL15A1-related disorder ⚠
- p.Ala1211Val No assertion criteria COL15A1-related disorder
- p.Ala442Thr No assertion criteria COL15A1-related disorder
- p.Arg163His No assertion criteria COL15A1-related disorder ⚠
- p.Glu506Asp No assertion criteria COL15A1-related disorder ⚠
- p.Gly1068= No assertion criteria COL15A1-related disorder
- p.Gly446Arg No assertion criteria COL15A1-related disorder ⚠
- p.Gly504Val No assertion criteria COL15A1-related disorder ⚠
- p.Gly838= No assertion criteria COL15A1-related disorder
- p.Ile1312Leu No assertion criteria COL15A1-related disorder
- p.Ile47Val No assertion criteria COL15A1-related disorder
- p.Lys1001Arg No assertion criteria COL15A1-related disorder ⚠
- p.Lys989Arg No assertion criteria COL15A1-related disorder ⚠
- p.Met204Val No assertion criteria COL15A1-related disorder
- p.Met422Ile No assertion criteria COL15A1-related disorder
- p.Phe851Leu No assertion criteria COL15A1-related disorder ⚠
- p.Pro1129= No assertion criteria COL15A1-related disorder
- p.Pro531Arg No assertion criteria COL15A1-related disorder
- p.Pro645Ser No assertion criteria COL15A1-related disorder ⚠
- p.Pro660Gln No assertion criteria COL15A1-related disorder ⚠
- p.Ser191Pro No assertion criteria COL15A1-related disorder
- p.Ser284= No assertion criteria COL15A1-related disorder
- p.Ser444= No assertion criteria COL15A1-related disorder
- p.Val1332Ile No assertion criteria COL15A1-related disorder
- p.Val224Met No assertion criteria COL15A1-related disorder ⚠
Likely benign 38
- p.Arg103His Single submitter
- p.Arg497Gln Single submitter
- p.Arg772Gln Single submitter
- p.Asp457Gly Single submitter
- p.Gly604Ser Single submitter ⚠
- p.Ile1264Val Single submitter
- p.Ile1304Met Single submitter ⚠
- p.Ile785Thr Single submitter ⚠
- p.Leu610= Single submitter
- p.Met389Val Single submitter
- p.Pro1120= Single submitter
- p.Pro864= Single submitter
- p.Ser1048Asn Single submitter
- p.Ser601Leu Single submitter
- p.Thr734Ala Single submitter
- p.Val1072Ile Single submitter
- p.Val668= Single submitter
- c.100+9C>A No assertion criteria COL15A1-related disorder
- c.1762-9T>C No assertion criteria COL15A1-related disorder
- c.3402+10A>G No assertion criteria COL15A1-related disorder
- p.Ala1148= No assertion criteria COL15A1-related disorder
- p.Ala25= No assertion criteria COL15A1-related disorder
- p.Asp828= No assertion criteria COL15A1-related disorder
- p.Glu260= No assertion criteria COL15A1-related disorder
- p.Glu417Lys No assertion criteria COL15A1-related disorder ⚠
- p.Gly1047Asp No assertion criteria COL15A1-related disorder
- p.Gly984Ala No assertion criteria COL15A1-related disorder ⚠
- p.His983= No assertion criteria COL15A1-related disorder
- p.Leu597= No assertion criteria COL15A1-related disorder
- p.Leu805= No assertion criteria COL15A1-related disorder
- p.Phe57= No assertion criteria COL15A1-related disorder
- p.Phe69= No assertion criteria COL15A1-related disorder
- p.Phe91= No assertion criteria COL15A1-related disorder
- p.Pro231= No assertion criteria COL15A1-related disorder
- p.Pro714Ser No assertion criteria COL15A1-related disorder ⚠
- p.Pro791= No assertion criteria COL15A1-related disorder
- p.Ser341= No assertion criteria COL15A1-related disorder
- p.Val96Met No assertion criteria COL15A1-related disorder ⚠
Uncertain significance 215
- p.Ala1006Ser Single submitter ⚠
- p.Ala1115Val Single submitter ⚠
- p.Ala1148Thr Single submitter ⚠
- p.Ala1193Val Single submitter ⚠
- p.Ala1244Ser Single submitter ⚠
- p.Ala1348Gly Single submitter ⚠
- p.Ala1386Thr Single submitter ⚠
- p.Ala345Ser Single submitter ⚠
- p.Ala345Thr Single submitter ⚠
- p.Ala413Thr Single submitter ⚠
- p.Ala413Val Single submitter ⚠
- p.Ala420Thr Single submitter ⚠
- p.Ala494Val Single submitter ⚠
- p.Ala498Thr Single submitter ⚠
- p.Ala73Thr Single submitter ⚠
- p.Ala761Val Single submitter ⚠
- p.Ala79Ser Single submitter ⚠
- p.Ala92Val Single submitter ⚠
- p.Ala948Gly Single submitter ⚠
- p.Arg1168Cys Single submitter ⚠
- p.Arg1333Cys Single submitter ⚠
- p.Arg1333Pro Single submitter ⚠
- p.Arg133Gln Single submitter ⚠
- p.Arg1372Gln Single submitter ⚠
- p.Arg497Trp Single submitter ⚠
- p.Arg618Lys Single submitter ⚠
- p.Arg684Lys Single submitter ⚠
- p.Arg876Met Single submitter ⚠
- p.Arg913Cys Single submitter ⚠
- p.Arg913His Single submitter ⚠
- p.Arg913Ser Single submitter ⚠
- p.Arg962Gln Single submitter ⚠
- p.Asn1030Lys Single submitter ⚠
- p.Asn1140His Single submitter ⚠
- p.Asn1371Lys Single submitter ⚠
- p.Asn393Tyr Single submitter ⚠
- p.Asp1032Asn Single submitter ⚠
- p.Asp112Gly Single submitter ⚠
- p.Asp1142Gly Single submitter ⚠
- p.Asp1187Asn Single submitter ⚠
- p.Asp1336Gly Single submitter ⚠
- p.Asp484His Single submitter ⚠
- p.Cys179Tyr Single submitter ⚠
- p.Gln1075Arg Single submitter ⚠
- p.Gln38Pro Single submitter ⚠
- p.Gln45Lys Single submitter ⚠
- p.Gln560Lys Single submitter ⚠
- p.Gln710Pro Single submitter ⚠
- p.Gln749Lys Single submitter ⚠
- p.Glu1000Lys Single submitter ⚠
- p.Glu197Gly Single submitter ⚠
- p.Glu213Lys Single submitter ⚠
- p.Glu239Asp Single submitter ⚠
- p.Glu251Lys Single submitter ⚠
- p.Glu291Asp Single submitter ⚠
- p.Glu366Ala Single submitter ⚠
- p.Glu366Lys Single submitter ⚠
- p.Glu376Lys Single submitter ⚠
- p.Glu496Lys Single submitter ⚠
- p.Glu573Gln Single submitter ⚠
- p.Glu740Lys Single submitter ⚠
- p.Glu820Val Single submitter ⚠
- p.Glu860Lys Single submitter ⚠
- p.Gly1034Arg Single submitter ⚠
- p.Gly1047Cys Single submitter ⚠
- p.Gly104Asp Single submitter ⚠
- p.Gly1093Arg Single submitter ⚠
- p.Gly1105Glu Single submitter ⚠
- p.Gly1130Arg Single submitter ⚠
- p.Gly1154Arg Single submitter ⚠
- p.Gly1172Asp Single submitter ⚠
- p.Gly1293Asp Single submitter ⚠
- p.Gly1309Ser Single submitter ⚠
- p.Gly31Cys Single submitter ⚠
- p.Gly434Arg Single submitter ⚠
- p.Gly48Ser Single submitter ⚠
- p.Gly523Ser Single submitter ⚠
- p.Gly527Ser Single submitter ⚠
- p.Gly571Ala Single submitter ⚠
- p.Gly594Val Single submitter ⚠
- p.Gly600Ser Single submitter ⚠
- p.Gly625Arg Single submitter ⚠
- p.Gly631Arg Single submitter ⚠
- p.Gly664Glu Single submitter ⚠
- p.Gly697Ser Single submitter ⚠
- p.Gly709Arg Single submitter ⚠
- p.Gly70Arg Single submitter ⚠
- p.Gly727Glu Single submitter ⚠
- p.Gly773Glu Single submitter ⚠
- p.Gly829Arg Single submitter ⚠
- p.Gly835Glu Single submitter ⚠
- p.Gly924Glu Single submitter ⚠
- p.Gly927Glu Single submitter ⚠
- p.Gly932Val Single submitter ⚠
- p.Gly987Arg Single submitter ⚠
- p.Gly993Ser Single submitter ⚠
- p.His1021Asp Single submitter ⚠
- p.His1149Leu Single submitter ⚠
- p.His1257Arg Single submitter ⚠
- p.His144Gln Single submitter ⚠
- p.His331Tyr Single submitter ⚠
- p.His797Leu Single submitter ⚠
- p.His810Gln Single submitter ⚠
- p.His810Tyr Single submitter ⚠
- p.His901Pro Single submitter ⚠
- p.Ile1184Leu Single submitter ⚠
- p.Ile1323Thr Single submitter ⚠
- p.Ile258Met Single submitter ⚠
- p.Ile338Val Single submitter ⚠
- p.Ile93Val Single submitter ⚠
- p.Leu1134Val Single submitter ⚠
- p.Leu1362Val Single submitter ⚠
- p.Leu219Phe Single submitter ⚠
- p.Leu259Phe Single submitter ⚠
- p.Leu574Phe Single submitter ⚠
- p.Leu801Phe Single submitter ⚠
- p.Leu919Phe Single submitter ⚠
- p.Lys1147Asn Single submitter ⚠
- p.Lys1279Arg Single submitter ⚠
- p.Lys1360Arg Single submitter ⚠
- p.Lys635Arg Single submitter ⚠
- p.Lys635Asn Single submitter ⚠
- p.Lys681Met Single submitter ⚠
- p.Lys755Glu Single submitter ⚠
- p.Lys799Asn Single submitter ⚠
- p.Lys896Arg Single submitter ⚠
- p.Met1225Val Single submitter ⚠
- p.Met1313Ile Single submitter ⚠
- p.Met1313Val Single submitter ⚠
- p.Met1383Ile Single submitter ⚠
- p.Met157Arg Single submitter ⚠
- p.Met204Ile Single submitter ⚠
- p.Met290Ile Single submitter ⚠
- p.Met389Thr Single submitter ⚠
- p.Met440Ile Single submitter ⚠
- p.Met780Leu Single submitter ⚠
- p.Met813Leu Single submitter ⚠
- p.Met886Ile Single submitter ⚠
- p.Met930Val Single submitter ⚠
- p.Phe815Cys Single submitter ⚠
- p.Phe87Leu Single submitter ⚠
- p.Phe88Cys Single submitter ⚠
- p.Pro1009Gln Single submitter ⚠
- p.Pro1087Leu Single submitter ⚠
- p.Pro1119His Single submitter ⚠
- p.Pro1191His Single submitter ⚠
- p.Pro1191Leu Single submitter ⚠
- p.Pro1355Arg Single submitter ⚠
- p.Pro226His Single submitter ⚠
- p.Pro22Arg Single submitter ⚠
- p.Pro269Thr Single submitter ⚠
- p.Pro286Ser Single submitter ⚠
- p.Pro402Thr Single submitter ⚠
- p.Pro482His Single submitter ⚠
- p.Pro535Leu Single submitter ⚠
- p.Pro549Ser Single submitter ⚠
- p.Pro575Ser Single submitter ⚠
- p.Pro577Arg Single submitter ⚠
- p.Pro580Leu Single submitter ⚠
- p.Pro583Leu Single submitter ⚠
- p.Pro621Thr Single submitter ⚠
- p.Pro623Ser Single submitter ⚠
- p.Pro653Leu Single submitter ⚠
- p.Pro675Ser Single submitter ⚠
- p.Pro702Ser Single submitter ⚠
- p.Pro719Leu Single submitter ⚠
- p.Pro719Ser Single submitter ⚠
- p.Pro725Ser Single submitter ⚠
- p.Pro759Thr Single submitter ⚠
- p.Pro791Ala Single submitter ⚠
- p.Pro791Leu Single submitter ⚠
- p.Pro825Leu Single submitter ⚠
- p.Pro849Ser Single submitter ⚠
- p.Pro864Leu Single submitter ⚠
- p.Pro884Arg Single submitter ⚠
- p.Pro884Thr Single submitter ⚠
- p.Pro895Ser Single submitter ⚠
- p.Pro943Ala Single submitter ⚠
- p.Ser101Thr Single submitter ⚠
- p.Ser1248Tyr Single submitter ⚠
- p.Ser1368Gly Single submitter ⚠
- p.Ser241Leu Single submitter ⚠
- p.Ser332Cys Single submitter ⚠
- p.Ser343Pro Single submitter ⚠
- p.Ser370Asn Single submitter ⚠
- p.Ser479Ile Single submitter ⚠
- p.Ser601Trp Single submitter ⚠
- p.Ser647Cys Single submitter ⚠
- p.Ser757Pro Single submitter ⚠
- p.Ser816Leu Single submitter ⚠
- p.Ser94Asn Single submitter ⚠
- p.Ser997Leu Single submitter ⚠
- p.Thr1358Met Single submitter ⚠
- p.Thr139Met Single submitter ⚠
- p.Thr246Ser Single submitter ⚠
- p.Thr265Ile Single submitter ⚠
- p.Thr282Ala Single submitter ⚠
- p.Thr33Arg Single submitter ⚠
- p.Thr33Ile Single submitter ⚠
- p.Thr360Ile Single submitter ⚠
- p.Thr360Pro Single submitter ⚠
- p.Thr371Ala Single submitter ⚠
- p.Thr44Met Single submitter ⚠
- p.Thr461Ile Single submitter ⚠
- p.Thr587Met Single submitter ⚠
- p.Thr672Ala Single submitter ⚠
- p.Thr760Met Single submitter ⚠
- p.Tyr67His Single submitter ⚠
- p.Val154Gly Single submitter ⚠
- p.Val156Leu Single submitter ⚠
- p.Val262Ile Single submitter ⚠
- p.Val330Leu Single submitter ⚠
- p.Val431Met Single submitter ⚠
- p.Val541Met Single submitter ⚠
- p.Val800Ile Single submitter ⚠