CORO7 — 8 ClinVar variants
All ClinVar germline CORO7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 5 flagged for review →
2 Benign · 1 Likely benign · 5 Uncertain significance
Full CORO7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 5
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 5
The independent predictors disagree with each other — read with care.
All CORO7 variants
Benign 2
- p.Leu132= Single submitter
- p.Pro740Ser Single submitter ⚠
Likely benign 1
- p.Ala296= Single submitter
Uncertain significance 5
- p.Arg601His Single submitter ⚠
- p.Asp50Asn Single submitter ⚠
- p.Lys151Thr Single submitter ⚠
- p.Val322Ile Single submitter ⚠
- c.2772+50C>T No assertion criteria mediastinal germ cell tumor