CTAGE9 — 118 ClinVar variants
All ClinVar germline CTAGE9 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 118 flagged for review →
118 Uncertain significance
Full CTAGE9 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 118
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 72
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- CTAGE9 p.Ala120Thr Uncertain significance Single submitter
- CTAGE9 p.Ala120Val Uncertain significance Single submitter
- CTAGE9 p.Ala122Val Uncertain significance Single submitter
- CTAGE9 p.Ala168Val Uncertain significance Single submitter
- CTAGE9 p.Ala208Val Uncertain significance Single submitter
- CTAGE9 p.Ala280Val Uncertain significance Single submitter
- CTAGE9 p.Ala321Thr Uncertain significance Single submitter
- CTAGE9 p.Ala668Thr Uncertain significance Single submitter
- CTAGE9 p.Ala748Val Uncertain significance Single submitter
- CTAGE9 p.Arg204Gln Uncertain significance Single submitter
- CTAGE9 p.Arg205Trp Uncertain significance Single submitter
- CTAGE9 p.Arg335Ile Uncertain significance Single submitter
- CTAGE9 p.Arg461Thr Uncertain significance Single submitter
- CTAGE9 p.Arg69Trp Uncertain significance Single submitter
- CTAGE9 p.Arg734Pro Uncertain significance Single submitter
- CTAGE9 p.Arg740Gly Uncertain significance Single submitter
- CTAGE9 p.Arg74Lys Uncertain significance Single submitter
- CTAGE9 p.Asn214Ser Uncertain significance Single submitter
- CTAGE9 p.Asn298Lys Uncertain significance Single submitter
- CTAGE9 p.Asn574Lys Uncertain significance Single submitter
- CTAGE9 p.Asp114Tyr Uncertain significance Single submitter
- CTAGE9 p.Asp309Glu Uncertain significance Single submitter
- CTAGE9 p.Asp33Ala Uncertain significance Single submitter
- CTAGE9 p.Asp508Asn Uncertain significance Single submitter
- CTAGE9 p.Cys521Arg Uncertain significance Single submitter
- CTAGE9 p.Gln540His Uncertain significance Single submitter
- CTAGE9 p.Gln9Arg Uncertain significance Single submitter
- CTAGE9 p.Glu113Gln Uncertain significance Single submitter
- CTAGE9 p.Glu124Ala Uncertain significance Single submitter
- CTAGE9 p.Glu150Gln Uncertain significance Single submitter
- CTAGE9 p.Glu232Ala Uncertain significance Single submitter
- CTAGE9 p.Glu494Asp Uncertain significance Single submitter
- CTAGE9 p.Glu75Lys Uncertain significance Single submitter
- CTAGE9 p.Gly313Arg Uncertain significance Single submitter
- CTAGE9 p.Gly515Val Uncertain significance Single submitter
- CTAGE9 p.Gly555Val Uncertain significance Single submitter
- CTAGE9 p.Gly558Glu Uncertain significance Single submitter
- CTAGE9 p.Gly703Ser Uncertain significance Single submitter
- CTAGE9 p.His160Tyr Uncertain significance Single submitter
- CTAGE9 p.His518Asn Uncertain significance Single submitter
- CTAGE9 p.His588Tyr Uncertain significance Single submitter
- CTAGE9 p.His747Pro Uncertain significance Single submitter
- CTAGE9 p.Ile207Thr Uncertain significance Single submitter
- CTAGE9 p.Ile50Thr Uncertain significance Single submitter
- CTAGE9 p.Ile701Val Uncertain significance Single submitter
- CTAGE9 p.Ile86Thr Uncertain significance Single submitter
- CTAGE9 p.Leu440Arg Uncertain significance Single submitter
- CTAGE9 p.Leu765Pro Uncertain significance Single submitter
- CTAGE9 p.Met276Ile Uncertain significance Single submitter
- CTAGE9 p.Met661Ile Uncertain significance Single submitter
- CTAGE9 p.Met752Ile Uncertain significance Single submitter
- CTAGE9 p.Phe390Leu Uncertain significance Single submitter
- CTAGE9 p.Phe497Leu Uncertain significance Single submitter
- CTAGE9 p.Pro310Leu Uncertain significance Single submitter
- CTAGE9 p.Pro32Ser Uncertain significance Single submitter
- CTAGE9 p.Pro4Ala Uncertain significance Single submitter
- CTAGE9 p.Pro529Ala Uncertain significance Single submitter
- CTAGE9 p.Pro639Ser Uncertain significance Single submitter
- CTAGE9 p.Pro658Leu Uncertain significance Single submitter
- CTAGE9 p.Ser201Gly Uncertain significance Single submitter
- CTAGE9 p.Ser29Thr Uncertain significance Single submitter
- CTAGE9 p.Ser424Thr Uncertain significance Single submitter
- CTAGE9 p.Ser538Pro Uncertain significance Single submitter
- CTAGE9 p.Ser563Ile Uncertain significance Single submitter
- CTAGE9 p.Ser664Arg Uncertain significance Single submitter
- CTAGE9 p.Thr268Ala Uncertain significance Single submitter
- CTAGE9 p.Thr287Lys Uncertain significance Single submitter
- CTAGE9 p.Thr288Lys Uncertain significance Single submitter
- CTAGE9 p.Thr361Ile Uncertain significance Single submitter
- CTAGE9 p.Tyr103Cys Uncertain significance Single submitter
- CTAGE9 p.Val253Ile Uncertain significance Single submitter
- CTAGE9 p.Val708Glu Uncertain significance Single submitter
Predictors split 46
The independent predictors disagree with each other — read with care.
- CTAGE9 p.Ala48Pro Uncertain significance Single submitter
- CTAGE9 p.Arg409Gln Uncertain significance Single submitter
- CTAGE9 p.Arg470Gln Uncertain significance Single submitter
- CTAGE9 p.Arg470Trp Uncertain significance Single submitter
- CTAGE9 p.Arg528Gln Uncertain significance Single submitter
- CTAGE9 p.Arg528Trp Uncertain significance Single submitter
- CTAGE9 p.Arg548Lys Uncertain significance Single submitter
- CTAGE9 p.Arg734Gln Uncertain significance Single submitter
- CTAGE9 p.Asn264His Uncertain significance Single submitter
- CTAGE9 p.Asn407His Uncertain significance Single submitter
- CTAGE9 p.Asp152Gly Uncertain significance Single submitter
- CTAGE9 p.Asp478Tyr Uncertain significance Single submitter
- CTAGE9 p.Glu332Lys Uncertain significance Single submitter
- CTAGE9 p.Glu389Gln Uncertain significance Single submitter
- CTAGE9 p.Glu405Lys Uncertain significance Single submitter
- CTAGE9 p.Glu414Asp Uncertain significance Single submitter
- CTAGE9 p.Glu473Lys Uncertain significance Single submitter
- CTAGE9 p.Glu87Lys Uncertain significance Single submitter
- CTAGE9 p.Gly20Cys Uncertain significance Single submitter
- CTAGE9 p.Gly712Asp Uncertain significance Single submitter
- CTAGE9 p.Gly718Arg Uncertain significance Single submitter
- CTAGE9 p.Gly744Asp Uncertain significance Single submitter
- CTAGE9 p.Gly760Arg Uncertain significance Single submitter
- CTAGE9 p.Gly760Val Uncertain significance Single submitter
- CTAGE9 p.Ile188Thr Uncertain significance Single submitter
- CTAGE9 p.Leu184Arg Uncertain significance Single submitter
- CTAGE9 p.Leu352Phe Uncertain significance Single submitter
- CTAGE9 p.Leu542Trp Uncertain significance Single submitter
- CTAGE9 p.Leu59Trp Uncertain significance Single submitter
- CTAGE9 p.Lys252Glu Uncertain significance Single submitter
- CTAGE9 p.Lys435Asn Uncertain significance Single submitter
- CTAGE9 p.Phe450Leu Uncertain significance Single submitter
- CTAGE9 p.Phe714Leu Uncertain significance Single submitter
- CTAGE9 p.Phe96Leu Uncertain significance Single submitter
- CTAGE9 p.Pro551Leu Uncertain significance Single submitter
- CTAGE9 p.Pro551Thr Uncertain significance Single submitter
- CTAGE9 p.Pro695Leu Uncertain significance Single submitter
- CTAGE9 p.Pro704Thr Uncertain significance Single submitter
- CTAGE9 p.Pro723Gln Uncertain significance Single submitter
- CTAGE9 p.Pro726Thr Uncertain significance Single submitter
- CTAGE9 p.Pro767Leu Uncertain significance Single submitter
- CTAGE9 p.Ser365Pro Uncertain significance Single submitter
- CTAGE9 p.Ser563Arg Uncertain significance Single submitter
- CTAGE9 p.Ser580Asn Uncertain significance Single submitter
- CTAGE9 p.Ser649Tyr Uncertain significance Single submitter
- CTAGE9 p.Trp234Arg Uncertain significance Single submitter
All CTAGE9 variants
Uncertain significance 118
- p.Ala120Thr Single submitter ⚠
- p.Ala120Val Single submitter ⚠
- p.Ala122Val Single submitter ⚠
- p.Ala168Val Single submitter ⚠
- p.Ala208Val Single submitter ⚠
- p.Ala280Val Single submitter ⚠
- p.Ala321Thr Single submitter ⚠
- p.Ala48Pro Single submitter ⚠
- p.Ala668Thr Single submitter ⚠
- p.Ala748Val Single submitter ⚠
- p.Arg204Gln Single submitter ⚠
- p.Arg205Trp Single submitter ⚠
- p.Arg335Ile Single submitter ⚠
- p.Arg409Gln Single submitter ⚠
- p.Arg461Thr Single submitter ⚠
- p.Arg470Gln Single submitter ⚠
- p.Arg470Trp Single submitter ⚠
- p.Arg528Gln Single submitter ⚠
- p.Arg528Trp Single submitter ⚠
- p.Arg548Lys Single submitter ⚠
- p.Arg69Trp Single submitter ⚠
- p.Arg734Gln Single submitter ⚠
- p.Arg734Pro Single submitter ⚠
- p.Arg740Gly Single submitter ⚠
- p.Arg74Lys Single submitter ⚠
- p.Asn214Ser Single submitter ⚠
- p.Asn264His Single submitter ⚠
- p.Asn298Lys Single submitter ⚠
- p.Asn407His Single submitter ⚠
- p.Asn574Lys Single submitter ⚠
- p.Asp114Tyr Single submitter ⚠
- p.Asp152Gly Single submitter ⚠
- p.Asp309Glu Single submitter ⚠
- p.Asp33Ala Single submitter ⚠
- p.Asp478Tyr Single submitter ⚠
- p.Asp508Asn Single submitter ⚠
- p.Cys521Arg Single submitter ⚠
- p.Gln540His Single submitter ⚠
- p.Gln9Arg Single submitter ⚠
- p.Glu113Gln Single submitter ⚠
- p.Glu124Ala Single submitter ⚠
- p.Glu150Gln Single submitter ⚠
- p.Glu232Ala Single submitter ⚠
- p.Glu332Lys Single submitter ⚠
- p.Glu389Gln Single submitter ⚠
- p.Glu405Lys Single submitter ⚠
- p.Glu414Asp Single submitter ⚠
- p.Glu473Lys Single submitter ⚠
- p.Glu494Asp Single submitter ⚠
- p.Glu75Lys Single submitter ⚠
- p.Glu87Lys Single submitter ⚠
- p.Gly20Cys Single submitter ⚠
- p.Gly313Arg Single submitter ⚠
- p.Gly515Val Single submitter ⚠
- p.Gly555Val Single submitter ⚠
- p.Gly558Glu Single submitter ⚠
- p.Gly703Ser Single submitter ⚠
- p.Gly712Asp Single submitter ⚠
- p.Gly718Arg Single submitter ⚠
- p.Gly744Asp Single submitter ⚠
- p.Gly760Arg Single submitter ⚠
- p.Gly760Val Single submitter ⚠
- p.His160Tyr Single submitter ⚠
- p.His518Asn Single submitter ⚠
- p.His588Tyr Single submitter ⚠
- p.His747Pro Single submitter ⚠
- p.Ile188Thr Single submitter ⚠
- p.Ile207Thr Single submitter ⚠
- p.Ile50Thr Single submitter ⚠
- p.Ile701Val Single submitter ⚠
- p.Ile86Thr Single submitter ⚠
- p.Leu184Arg Single submitter ⚠
- p.Leu352Phe Single submitter ⚠
- p.Leu440Arg Single submitter ⚠
- p.Leu542Trp Single submitter ⚠
- p.Leu59Trp Single submitter ⚠
- p.Leu765Pro Single submitter ⚠
- p.Lys252Glu Single submitter ⚠
- p.Lys435Asn Single submitter ⚠
- p.Met276Ile Single submitter ⚠
- p.Met661Ile Single submitter ⚠
- p.Met752Ile Single submitter ⚠
- p.Phe390Leu Single submitter ⚠
- p.Phe450Leu Single submitter ⚠
- p.Phe497Leu Single submitter ⚠
- p.Phe714Leu Single submitter ⚠
- p.Phe96Leu Single submitter ⚠
- p.Pro310Leu Single submitter ⚠
- p.Pro32Ser Single submitter ⚠
- p.Pro4Ala Single submitter ⚠
- p.Pro529Ala Single submitter ⚠
- p.Pro551Leu Single submitter ⚠
- p.Pro551Thr Single submitter ⚠
- p.Pro639Ser Single submitter ⚠
- p.Pro658Leu Single submitter ⚠
- p.Pro695Leu Single submitter ⚠
- p.Pro704Thr Single submitter ⚠
- p.Pro723Gln Single submitter ⚠
- p.Pro726Thr Single submitter ⚠
- p.Pro767Leu Single submitter ⚠
- p.Ser201Gly Single submitter ⚠
- p.Ser29Thr Single submitter ⚠
- p.Ser365Pro Single submitter ⚠
- p.Ser424Thr Single submitter ⚠
- p.Ser538Pro Single submitter ⚠
- p.Ser563Arg Single submitter ⚠
- p.Ser563Ile Single submitter ⚠
- p.Ser580Asn Single submitter ⚠
- p.Ser649Tyr Single submitter ⚠
- p.Ser664Arg Single submitter ⚠
- p.Thr268Ala Single submitter ⚠
- p.Thr287Lys Single submitter ⚠
- p.Thr288Lys Single submitter ⚠
- p.Thr361Ile Single submitter ⚠
- p.Trp234Arg Single submitter ⚠
- p.Tyr103Cys Single submitter ⚠
- p.Val253Ile Single submitter ⚠
- p.Val708Glu Single submitter ⚠