Sugi Variant

Sugi Variant/CTBP2

CTBP2 — 59 ClinVar variants

All ClinVar germline CTBP2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 3 flagged for review →

3 Pathogenic · 23 Benign · 31 Likely benign · 2 Uncertain significance

Full CTBP2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 3

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors vs ClinVar 1

ClinVar calls these pathogenic, but the computational predictors lean tolerated — the highest-value review flag.

Predictors split 2

The independent predictors disagree with each other — read with care.

All CTBP2 variants

Pathogenic 3

Benign 23

Likely benign 31

Uncertain significance 2