CUL9 — 414 ClinVar variants
All ClinVar germline CUL9 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 344 flagged for review →
2 Conflicting · 22 Benign · 52 Likely benign · 338 Uncertain significance
Full CUL9 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 344
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 1
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
Predictors lean, ClinVar uncertain 219
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 219
- CUL9 p.Ala1004Val Uncertain significance Single submitter
- CUL9 p.Ala1093Pro Uncertain significance Single submitter
- CUL9 p.Ala1112Thr Uncertain significance Single submitter
- CUL9 p.Ala111Thr Uncertain significance Single submitter
- CUL9 p.Ala121Glu Uncertain significance Single submitter
- CUL9 p.Ala1388Val Uncertain significance Single submitter
- CUL9 p.Ala1459Thr Uncertain significance Single submitter
- CUL9 p.Ala1459Val Uncertain significance Single submitter
- CUL9 p.Ala1845Asp Uncertain significance Single submitter
- CUL9 p.Ala192Ser Uncertain significance Single submitter
- CUL9 p.Ala1993Val Uncertain significance Single submitter
- CUL9 p.Ala2060Thr Uncertain significance Single submitter
- CUL9 p.Ala2306Glu Uncertain significance Single submitter
- CUL9 p.Ala2319Gly Uncertain significance Single submitter
- CUL9 p.Ala2335Val Uncertain significance Single submitter
- CUL9 p.Ala2515Thr Uncertain significance Single submitter
- CUL9 p.Ala400Thr Uncertain significance Single submitter
- CUL9 p.Ala447Thr Uncertain significance Single submitter
- CUL9 p.Ala450Val Uncertain significance Single submitter
- CUL9 p.Ala533Asp Uncertain significance Single submitter
- CUL9 p.Ala533Pro Uncertain significance Single submitter
- CUL9 p.Ala635Glu Uncertain significance Single submitter
- CUL9 p.Ala683Thr Uncertain significance Single submitter
- CUL9 p.Ala74Thr Uncertain significance Single submitter
- CUL9 p.Ala904Thr Uncertain significance Single submitter
- CUL9 p.Ala961Val Uncertain significance Single submitter
- CUL9 p.Arg102Gln Uncertain significance Single submitter
- CUL9 p.Arg1102Gln Uncertain significance Single submitter
- CUL9 p.Arg1277His Uncertain significance Single submitter
- CUL9 p.Arg1289Gln Uncertain significance Single submitter
- CUL9 p.Arg1307Trp Uncertain significance Single submitter
- CUL9 p.Arg1312His Uncertain significance Single submitter
- CUL9 p.Arg1334Gln Uncertain significance Single submitter
- CUL9 p.Arg1356His Uncertain significance Single submitter
- CUL9 p.Arg1405Lys Uncertain significance Single submitter
- CUL9 p.Arg1445Gln Uncertain significance Single submitter
- CUL9 p.Arg1454Gly Uncertain significance Single submitter
- CUL9 p.Arg1645His Uncertain significance Single submitter
- CUL9 p.Arg17Gln Uncertain significance Single submitter
- CUL9 p.Arg1833Gln Uncertain significance Single submitter
- CUL9 p.Arg1841His Uncertain significance Single submitter
- CUL9 p.Arg184Gln Uncertain significance Single submitter
- CUL9 p.Arg1945Trp Uncertain significance Single submitter
- CUL9 p.Arg1961Gln Uncertain significance Single submitter
- CUL9 p.Arg2011His Uncertain significance Single submitter
- CUL9 p.Arg2168His Uncertain significance Single submitter
- CUL9 p.Arg2288Leu Uncertain significance Single submitter
- CUL9 p.Arg2343Trp Uncertain significance Single submitter
- CUL9 p.Arg2413Gln Uncertain significance Single submitter
-
CUL9 p.Arg2413Trp
Uncertain significance
Single submitter
Single umbilical artery
- CUL9 p.Arg2431Gln Uncertain significance Single submitter
- CUL9 p.Arg262His Uncertain significance Single submitter
- CUL9 p.Arg291Lys Uncertain significance Single submitter
- CUL9 p.Arg295Gln Uncertain significance Single submitter
- CUL9 p.Arg295Trp Uncertain significance Single submitter
- CUL9 p.Arg315Gly Uncertain significance Single submitter
- CUL9 p.Arg321Gln Uncertain significance Single submitter
- CUL9 p.Arg321Pro Uncertain significance Single submitter
- CUL9 p.Arg321Trp Uncertain significance Single submitter
- CUL9 p.Arg332Gln Uncertain significance Single submitter
- CUL9 p.Arg372His Uncertain significance Single submitter
- CUL9 p.Arg586Gln Uncertain significance Single submitter
- CUL9 p.Arg5Gln Uncertain significance Single submitter
- CUL9 p.Arg674Leu Uncertain significance Single submitter
- CUL9 p.Arg715Gln Uncertain significance Single submitter
- CUL9 p.Arg816Gly Uncertain significance Single submitter
- CUL9 p.Arg83Trp Uncertain significance Single submitter
- CUL9 p.Arg953Gln Uncertain significance Single submitter
- CUL9 p.Asn177Ser Uncertain significance Single submitter
- CUL9 p.Asn2112Ile Uncertain significance Single submitter
- CUL9 p.Asn308Ser Uncertain significance Single submitter
- CUL9 p.Asn322His Uncertain significance Single submitter
- CUL9 p.Asn410Lys Uncertain significance Single submitter
- CUL9 p.Asn922Ser Uncertain significance Single submitter
- CUL9 p.Asp1150Gly Uncertain significance Single submitter
- CUL9 p.Asp1361His Uncertain significance Single submitter
- CUL9 p.Asp1455Glu Uncertain significance Single submitter
- CUL9 p.Asp212Gly Uncertain significance Single submitter
- CUL9 p.Asp2403Glu Uncertain significance Single submitter
- CUL9 p.Asp678Ala Uncertain significance Single submitter
- CUL9 p.Asp945Val Uncertain significance Single submitter
- CUL9 p.Asp9Glu Uncertain significance Single submitter
- CUL9 p.Cys1099Tyr Uncertain significance Single submitter
- CUL9 p.Cys1315Arg Uncertain significance Single submitter
- CUL9 p.Cys1371Gly Uncertain significance Single submitter
- CUL9 p.Cys1704Ser Uncertain significance Single submitter
- CUL9 p.Cys1969Phe Uncertain significance Single submitter
- CUL9 p.Cys2404Tyr Uncertain significance Single submitter
- CUL9 p.Cys47Gly Uncertain significance Single submitter
- CUL9 p.Gln1094Lys Uncertain significance Single submitter
- CUL9 p.Gln1309His Uncertain significance Single submitter
- CUL9 p.Gln1556Arg Uncertain significance Single submitter
- CUL9 p.Gln1598Lys Uncertain significance Single submitter
- CUL9 p.Gln2012Arg Uncertain significance Single submitter
- CUL9 p.Gln2061Arg Uncertain significance Single submitter
- CUL9 p.Gln339Arg Uncertain significance Single submitter
- CUL9 p.Glu1035Asp Uncertain significance Single submitter
- CUL9 p.Glu109Lys Uncertain significance Single submitter
- CUL9 p.Glu164Asp Uncertain significance Single submitter
- CUL9 p.Glu1689Gly Uncertain significance Single submitter
- CUL9 p.Glu2036Gln Uncertain significance Single submitter
- CUL9 p.Glu2247Lys Uncertain significance Single submitter
- CUL9 p.Glu23Gln Uncertain significance Single submitter
- CUL9 p.Glu2470Asp Uncertain significance Single submitter
- CUL9 p.Glu312Gly Uncertain significance Single submitter
- CUL9 p.Glu545Lys Uncertain significance Single submitter
- CUL9 p.Glu92Ala Uncertain significance Single submitter
- CUL9 p.Gly1006Arg Uncertain significance Single submitter
- CUL9 p.Gly1917Glu Uncertain significance Single submitter
- CUL9 p.Gly2126Arg Uncertain significance Single submitter
- CUL9 p.Gly213Asp Uncertain significance Single submitter
- CUL9 p.Gly213Val Uncertain significance Single submitter
- CUL9 p.Gly2178Arg Uncertain significance Single submitter
- CUL9 p.Gly2213Ser Uncertain significance Single submitter
- CUL9 p.Gly282Arg Uncertain significance Single submitter
- CUL9 p.Gly454Arg Uncertain significance Single submitter
- CUL9 p.Gly474Trp Uncertain significance Single submitter
- CUL9 p.Gly902Arg Uncertain significance Single submitter
- CUL9 p.Gly95Ala Uncertain significance Single submitter
- CUL9 p.Gly975Asp Uncertain significance Single submitter
- CUL9 p.His1155Arg Uncertain significance Single submitter
- CUL9 p.His1427Tyr Uncertain significance Single submitter
- CUL9 p.His2259Arg Uncertain significance Single submitter
- CUL9 p.His717Asn Uncertain significance Single submitter
- CUL9 p.Ile1053Val Uncertain significance Single submitter
- CUL9 p.Ile1245Val Uncertain significance Single submitter
- CUL9 p.Ile1472Val Uncertain significance Single submitter
- CUL9 p.Ile155Met Uncertain significance Single submitter
- CUL9 p.Ile155Val Uncertain significance Single submitter
- CUL9 p.Ile1930Val Uncertain significance Single submitter
- CUL9 p.Ile2129Thr Uncertain significance Single submitter
- CUL9 p.Leu1153Ile Uncertain significance Single submitter
- CUL9 p.Leu1429Val Uncertain significance Single submitter
- CUL9 p.Leu1488Pro Uncertain significance Single submitter
- CUL9 p.Leu1618Pro Uncertain significance Single submitter
- CUL9 p.Leu1931Met Uncertain significance Single submitter
- CUL9 p.Leu2019Ile Uncertain significance Single submitter
- CUL9 p.Leu2111Trp Uncertain significance Single submitter
- CUL9 p.Leu737Met Uncertain significance Single submitter
- CUL9 p.Leu767Ile Uncertain significance Single submitter
- CUL9 p.Leu79Pro Uncertain significance Single submitter
- CUL9 p.Leu967Met Uncertain significance Single submitter
- CUL9 p.Leu984Ile Uncertain significance Single submitter
- CUL9 p.Leu999Val Uncertain significance Single submitter
- CUL9 p.Lys1657Asn Uncertain significance Single submitter
- CUL9 p.Lys2291Arg Uncertain significance Single submitter
- CUL9 p.Lys293Arg Uncertain significance Single submitter
- CUL9 p.Met1746Ile Uncertain significance Single submitter
- CUL9 p.Met1997Arg Uncertain significance Single submitter
- CUL9 p.Met218Val Uncertain significance Single submitter
Predictors split 124
The independent predictors disagree with each other — read with care.
- CUL9 p.Glu617Lys Likely benign Multiple submitters
- CUL9 p.Ala131Val Uncertain significance Single submitter
- CUL9 p.Ala1419Val Uncertain significance Single submitter
- CUL9 p.Ala1602Val Uncertain significance Single submitter
- CUL9 p.Ala1616Pro Uncertain significance Single submitter
- CUL9 p.Ala198Val Uncertain significance Single submitter
- CUL9 p.Ala2024Thr Uncertain significance Single submitter
- CUL9 p.Ala2145Val Uncertain significance Single submitter
- CUL9 p.Ala2342Thr Uncertain significance Single submitter
- CUL9 p.Ala305Thr Uncertain significance Single submitter
- CUL9 p.Arg1021Gln Uncertain significance Single submitter
- CUL9 p.Arg1211His Uncertain significance Single submitter
- CUL9 p.Arg1260Gln Uncertain significance Single submitter
- CUL9 p.Arg1269His Uncertain significance Single submitter
- CUL9 p.Arg1280Cys Uncertain significance Single submitter
- CUL9 p.Arg1291Gln Uncertain significance Single submitter
- CUL9 p.Arg1334Trp Uncertain significance Single submitter
- CUL9 p.Arg1409Trp Uncertain significance Single submitter
- CUL9 p.Arg1456Trp Uncertain significance Single submitter
- CUL9 p.Arg1500Cys Uncertain significance Single submitter
- CUL9 p.Arg1527Cys Uncertain significance Single submitter
- CUL9 p.Arg1527His Uncertain significance Single submitter
- CUL9 p.Arg1628Cys Uncertain significance Single submitter
- CUL9 p.Arg1750Gln Uncertain significance Single submitter
- CUL9 p.Arg1750Trp Uncertain significance Single submitter
- CUL9 p.Arg1759Trp Uncertain significance Single submitter
- CUL9 p.Arg201Trp Uncertain significance Single submitter
- CUL9 p.Arg2066Gly Uncertain significance Single submitter
- CUL9 p.Arg2130Cys Uncertain significance Single submitter
- CUL9 p.Arg2292Gln Uncertain significance Single submitter
- CUL9 p.Arg2343Gln Uncertain significance Single submitter
- CUL9 p.Arg364Cys Uncertain significance Single submitter
- CUL9 p.Arg364Gly Uncertain significance Single submitter
- CUL9 p.Arg390Gln Uncertain significance Single submitter
- CUL9 p.Arg390Trp Uncertain significance Single submitter
- CUL9 p.Arg407Trp Uncertain significance Single submitter
- CUL9 p.Arg425His Uncertain significance Single submitter
- CUL9 p.Arg5Trp Uncertain significance Single submitter
- CUL9 p.Arg669Trp Uncertain significance Single submitter
- CUL9 p.Arg894Thr Uncertain significance Single submitter
- CUL9 p.Arg923His Uncertain significance Single submitter
- CUL9 p.Asp1496Gly Uncertain significance Single submitter
- CUL9 p.Asp1656Asn Uncertain significance Single submitter
- CUL9 p.Asp1944Gly Uncertain significance Single submitter
- CUL9 p.Asp2045Ala Uncertain significance Single submitter
- CUL9 p.Asp2403Asn Uncertain significance Single submitter
- CUL9 p.Asp2471Asn Uncertain significance Single submitter
- CUL9 p.Asp2471His Uncertain significance Single submitter
- CUL9 p.Asp2493Asn Uncertain significance Single submitter
- CUL9 p.Asp638Asn Uncertain significance Single submitter
-
CUL9 p.Cys2171Trp
Uncertain significance
Single submitter
CUL9-related disorder
- CUL9 p.Gln211His Uncertain significance Single submitter
- CUL9 p.Gln384His Uncertain significance Single submitter
- CUL9 p.Glu1052Lys Uncertain significance Single submitter
- CUL9 p.Glu1514Lys Uncertain significance Single submitter
- CUL9 p.Glu1579Gly Uncertain significance Single submitter
- CUL9 p.Glu1641Gly Uncertain significance Single submitter
- CUL9 p.Glu2003Lys Uncertain significance Single submitter
- CUL9 p.Glu2020Lys Uncertain significance Single submitter
- CUL9 p.Glu2464Lys Uncertain significance Single submitter
- CUL9 p.Glu403Asp Uncertain significance Single submitter
- CUL9 p.Glu606Gly Uncertain significance Single submitter
- CUL9 p.Glu624Lys Uncertain significance Single submitter
- CUL9 p.Gly134Val Uncertain significance Single submitter
- CUL9 p.Gly2185Asp Uncertain significance Single submitter
- CUL9 p.Gly438Asp Uncertain significance Single submitter
- CUL9 p.Gly943Cys Uncertain significance Single submitter
- CUL9 p.His2032Tyr Uncertain significance Single submitter
- CUL9 p.Ile2129Met Uncertain significance Single submitter
- CUL9 p.Leu1769Val Uncertain significance Single submitter
- CUL9 p.Leu1846Pro Uncertain significance Single submitter
- CUL9 p.Leu2049Gln Uncertain significance Single submitter
- CUL9 p.Lys1781Thr Uncertain significance Single submitter
- CUL9 p.Lys2256Asn Uncertain significance Single submitter
- CUL9 p.Met1209Ile Uncertain significance Single submitter
- CUL9 p.Met1209Val Uncertain significance Single submitter
- CUL9 p.Met304Ile Uncertain significance Single submitter
- CUL9 p.Met433Val Uncertain significance Single submitter
- CUL9 p.Phe1306Leu Uncertain significance Single submitter
- CUL9 p.Phe1487Leu Uncertain significance Single submitter
- CUL9 p.Phe1724Leu Uncertain significance Single submitter
- CUL9 p.Pro1005Leu Uncertain significance Single submitter
- CUL9 p.Pro1179Ala Uncertain significance Single submitter
- CUL9 p.Pro1300Arg Uncertain significance Single submitter
- CUL9 p.Pro1386Ala Uncertain significance Single submitter
- CUL9 p.Pro2046Arg Uncertain significance Single submitter
- CUL9 p.Pro2046His Uncertain significance Single submitter
- CUL9 p.Pro479Leu Uncertain significance Single submitter
- CUL9 p.Pro851Ser Uncertain significance Single submitter
- CUL9 p.Ser1385Phe Uncertain significance Single submitter
- CUL9 p.Ser1696Cys Uncertain significance Single submitter
- CUL9 p.Ser1701Ala Uncertain significance Single submitter
- CUL9 p.Ser1732Phe Uncertain significance Single submitter
- CUL9 p.Ser1800Phe Uncertain significance Single submitter
- CUL9 p.Ser1976Tyr Uncertain significance Single submitter
- CUL9 p.Ser2135Leu Uncertain significance Single submitter
- CUL9 p.Ser2155Cys Uncertain significance Single submitter
- CUL9 p.Ser637Ile Uncertain significance Single submitter
- CUL9 p.Ser68Leu Uncertain significance Single submitter
- CUL9 p.Ser99Asn Conflicting Single submitter
- CUL9 p.Thr1247Ala Uncertain significance Single submitter
- CUL9 p.Thr1251Lys Uncertain significance Single submitter
- CUL9 p.Thr1314Ala Uncertain significance Single submitter
- CUL9 p.Thr1541Ile Uncertain significance Single submitter
- CUL9 p.Thr2407Met Uncertain significance Single submitter
- CUL9 p.Thr426Ala Uncertain significance Single submitter
- CUL9 p.Thr626Asn Uncertain significance Single submitter
- CUL9 p.Thr632Asn Uncertain significance Single submitter
- CUL9 p.Thr632Ile Uncertain significance Single submitter
- CUL9 p.Thr896Met Uncertain significance Single submitter
- CUL9 p.Tyr1115Asn Uncertain significance Single submitter
- CUL9 p.Tyr1552Asp Uncertain significance Single submitter
- CUL9 p.Val1087Ile Uncertain significance Single submitter
- CUL9 p.Val2065Ile Uncertain significance Single submitter
- CUL9 p.Val688Ala Uncertain significance Single submitter
- CUL9 p.Val731Met Uncertain significance Single submitter
- CUL9 p.Val749Met Uncertain significance Single submitter
- CUL9 p.Val854Met Uncertain significance Single submitter
- CUL9 p.Val981Met Uncertain significance Single submitter
-
CUL9 p.Arg1645Cys
Likely benign
No assertion criteria
CUL9-related disorder
-
CUL9 p.Arg2316Trp
Likely benign
No assertion criteria
CUL9-related disorder
-
CUL9 p.Cys1076Tyr
Likely benign
No assertion criteria
CUL9-related disorder
-
CUL9 p.Ser1451Ile
Likely benign
No assertion criteria
CUL9-related disorder
-
CUL9 p.Thr1251Met
Likely benign
No assertion criteria
CUL9-related disorder
All CUL9 variants
Conflicting classifications of pathogenicity 2
- p.Met11Leu Single submitter ⚠
- p.Ser99Asn Single submitter ⚠
Benign 22
- p.Ala2145= Single submitter
- p.Gln1404= Single submitter
- c.3051-8C>T No assertion criteria CUL9-related disorder
- p.Ala2255Thr No assertion criteria CUL9-related disorder
- p.Ala683= No assertion criteria CUL9-related disorder
- p.Asp2211= No assertion criteria CUL9-related disorder
- p.Gln297Lys No assertion criteria CUL9-related disorder
- p.Gln359Glu No assertion criteria CUL9-related disorder
- p.Gly106= No assertion criteria CUL9-related disorder
- p.Gly156Arg No assertion criteria CUL9-related disorder
- p.Gly282Glu No assertion criteria CUL9-related disorder
- p.Gly374= No assertion criteria CUL9-related disorder
- p.Gly958del No assertion criteria CUL9-related disorder
- p.His2058Pro No assertion criteria CUL9-related disorder
- p.Ile1205= No assertion criteria CUL9-related disorder
- p.Leu175= No assertion criteria CUL9-related disorder
- p.Pro2324= No assertion criteria CUL9-related disorder
- p.Ser1461= No assertion criteria CUL9-related disorder
- p.Thr2180Ile No assertion criteria CUL9-related disorder
- p.Thr584Ala No assertion criteria CUL9-related disorder
- p.Tyr152= No assertion criteria CUL9-related disorder
- p.Val1926= No assertion criteria CUL9-related disorder
Likely benign 52
- p.Glu617Lys Multiple submitters ⚠
- c.3385-6C>T Single submitter
- c.5034_5042del Single submitter
- c.7284+4C>G Single submitter
- c.7284+5T>G Single submitter
- p.Arg973His Single submitter
- p.Asn2333Ser Single submitter
- p.Asn577Asp Single submitter
- p.Cys1244Tyr Single submitter
- p.Gln1653Glu Single submitter
- p.Glu1974Lys Single submitter
- p.Glu991= Single submitter
- p.Gly1246Ser Single submitter
- p.Gly1829Arg Single submitter
- p.Gly530Ala Single submitter
- p.His1835Arg Single submitter
- p.Ile1697Val Single submitter
- p.Ile819Val Single submitter
- p.Leu1652= Single submitter
- p.Leu279Pro Single submitter
- p.Met328Thr Single submitter
- p.Met472Val Single submitter
- p.Pro579Leu Single submitter
- p.Ser1066Leu Single submitter
- p.Ser1241= Single submitter
- p.Ser1461Leu Single submitter
- p.Trp2442Arg Single submitter
- p.Val1809Leu Single submitter
- p.Val459= Single submitter
- c.2389-7C>A No assertion criteria CUL9-related disorder
- c.3384+9C>T No assertion criteria CUL9-related disorder
- c.5023-7C>T No assertion criteria CUL9-related disorder
- p.Arg1645Cys No assertion criteria CUL9-related disorder ⚠
- p.Arg1730His No assertion criteria CUL9-related disorder
- p.Arg2316Trp No assertion criteria CUL9-related disorder ⚠
- p.Arg2389Gln No assertion criteria CUL9-related disorder
- p.Asn2246= No assertion criteria CUL9-related disorder
- p.Asp2080= No assertion criteria CUL9-related disorder
- p.Cys1076Tyr No assertion criteria CUL9-related disorder ⚠
- p.Leu1156= No assertion criteria CUL9-related disorder
- p.Leu170= No assertion criteria CUL9-related disorder
- p.Leu1848= No assertion criteria CUL9-related disorder
- p.Leu2005= No assertion criteria CUL9-related disorder
- p.Leu79= No assertion criteria CUL9-related disorder
- p.Pro1147= No assertion criteria CUL9-related disorder
- p.Pro483= No assertion criteria CUL9-related disorder
- p.Ser1451Ile No assertion criteria CUL9-related disorder ⚠
- p.Thr1251Met No assertion criteria CUL9-related disorder ⚠
- p.Tyr2150= No assertion criteria CUL9-related disorder
- p.Tyr2348= No assertion criteria CUL9-related disorder
- p.Val429= No assertion criteria CUL9-related disorder
- p.Val684= No assertion criteria CUL9-related disorder
Uncertain significance 338
Showing the top 300 by review status; the full set is in the sitemap.
- p.Ala1004Val Single submitter ⚠
- p.Ala1093Pro Single submitter ⚠
- p.Ala1112Thr Single submitter ⚠
- p.Ala111Thr Single submitter ⚠
- p.Ala121Glu Single submitter ⚠
- p.Ala131Val Single submitter ⚠
- p.Ala1388Val Single submitter ⚠
- p.Ala1419Val Single submitter ⚠
- p.Ala1459Thr Single submitter ⚠
- p.Ala1459Val Single submitter ⚠
- p.Ala1602Val Single submitter ⚠
- p.Ala1616Pro Single submitter ⚠
- p.Ala1845Asp Single submitter ⚠
- p.Ala192Ser Single submitter ⚠
- p.Ala198Val Single submitter ⚠
- p.Ala1993Val Single submitter ⚠
- p.Ala2024Thr Single submitter ⚠
- p.Ala2060Thr Single submitter ⚠
- p.Ala2145Val Single submitter ⚠
- p.Ala2306Glu Single submitter ⚠
- p.Ala2319Gly Single submitter ⚠
- p.Ala2335Val Single submitter ⚠
- p.Ala2342Thr Single submitter ⚠
- p.Ala2515Thr Single submitter ⚠
- p.Ala305Thr Single submitter ⚠
- p.Ala400Thr Single submitter ⚠
- p.Ala447Thr Single submitter ⚠
- p.Ala450Val Single submitter ⚠
- p.Ala533Asp Single submitter ⚠
- p.Ala533Pro Single submitter ⚠
- p.Ala635Glu Single submitter ⚠
- p.Ala683Thr Single submitter ⚠
- p.Ala74Thr Single submitter ⚠
- p.Ala904Thr Single submitter ⚠
- p.Ala961Val Single submitter ⚠
- p.Arg1021Gln Single submitter ⚠
- p.Arg102Gln Single submitter ⚠
- p.Arg1102Gln Single submitter ⚠
- p.Arg1211His Single submitter ⚠
- p.Arg1260Gln Single submitter ⚠
- p.Arg1269His Single submitter ⚠
- p.Arg1277His Single submitter ⚠
- p.Arg1280Cys Single submitter ⚠
- p.Arg1289Gln Single submitter ⚠
- p.Arg1291Gln Single submitter ⚠
- p.Arg1307Trp Single submitter ⚠
- p.Arg1312His Single submitter ⚠
- p.Arg1334Gln Single submitter ⚠
- p.Arg1334Trp Single submitter ⚠
- p.Arg1356His Single submitter ⚠
- p.Arg1405Lys Single submitter ⚠
- p.Arg1409Trp Single submitter ⚠
- p.Arg1445Gln Single submitter ⚠
- p.Arg1454Gly Single submitter ⚠
- p.Arg1456Trp Single submitter ⚠
- p.Arg1500Cys Single submitter ⚠
- p.Arg1527Cys Single submitter ⚠
- p.Arg1527His Single submitter ⚠
- p.Arg1628Cys Single submitter ⚠
- p.Arg1645His Single submitter ⚠
- p.Arg1750Gln Single submitter ⚠
- p.Arg1750Trp Single submitter ⚠
- p.Arg1759Trp Single submitter ⚠
- p.Arg17Gln Single submitter ⚠
- p.Arg1833Gln Single submitter ⚠
- p.Arg1841His Single submitter ⚠
- p.Arg184Gln Single submitter ⚠
- p.Arg1945Trp Single submitter ⚠
- p.Arg1961Gln Single submitter ⚠
- p.Arg2011His Single submitter ⚠
- p.Arg201Trp Single submitter ⚠
- p.Arg2066Gly Single submitter ⚠
- p.Arg2130Cys Single submitter ⚠
- p.Arg2168His Single submitter ⚠
- p.Arg2288Leu Single submitter ⚠
- p.Arg2292Gln Single submitter ⚠
- p.Arg2343Gln Single submitter ⚠
- p.Arg2343Trp Single submitter ⚠
- p.Arg2413Gln Single submitter ⚠
- p.Arg2413Trp Single submitter Single umbilical artery ⚠
- p.Arg2431Gln Single submitter ⚠
- p.Arg262His Single submitter ⚠
- p.Arg291Lys Single submitter ⚠
- p.Arg295Gln Single submitter ⚠
- p.Arg295Trp Single submitter ⚠
- p.Arg315Gly Single submitter ⚠
- p.Arg321Gln Single submitter ⚠
- p.Arg321Pro Single submitter ⚠
- p.Arg321Trp Single submitter ⚠
- p.Arg332Gln Single submitter ⚠
- p.Arg364Cys Single submitter ⚠
- p.Arg364Gly Single submitter ⚠
- p.Arg372His Single submitter ⚠
- p.Arg390Gln Single submitter ⚠
- p.Arg390Trp Single submitter ⚠
- p.Arg407Trp Single submitter ⚠
- p.Arg425His Single submitter ⚠
- p.Arg586Gln Single submitter ⚠
- p.Arg5Gln Single submitter ⚠
- p.Arg5Trp Single submitter ⚠
- p.Arg669Trp Single submitter ⚠
- p.Arg674Leu Single submitter ⚠
- p.Arg715Gln Single submitter ⚠
- p.Arg816Gly Single submitter ⚠
- p.Arg83Trp Single submitter ⚠
- p.Arg894Thr Single submitter ⚠
- p.Arg923His Single submitter ⚠
- p.Arg953Gln Single submitter ⚠
- p.Asn177Ser Single submitter ⚠
- p.Asn2112Ile Single submitter ⚠
- p.Asn308Ser Single submitter ⚠
- p.Asn322His Single submitter ⚠
- p.Asn410Lys Single submitter ⚠
- p.Asn922Ser Single submitter ⚠
- p.Asp1150Gly Single submitter ⚠
- p.Asp1361His Single submitter ⚠
- p.Asp1455Glu Single submitter ⚠
- p.Asp1496Gly Single submitter ⚠
- p.Asp1656Asn Single submitter ⚠
- p.Asp1944Gly Single submitter ⚠
- p.Asp2045Ala Single submitter ⚠
- p.Asp212Gly Single submitter ⚠
- p.Asp2403Asn Single submitter ⚠
- p.Asp2403Glu Single submitter ⚠
- p.Asp2471Asn Single submitter ⚠
- p.Asp2471His Single submitter ⚠
- p.Asp2493Asn Single submitter ⚠
- p.Asp638Asn Single submitter ⚠
- p.Asp678Ala Single submitter ⚠
- p.Asp945Val Single submitter ⚠
- p.Asp9Glu Single submitter ⚠
- p.Cys1099Tyr Single submitter ⚠
- p.Cys1315Arg Single submitter ⚠
- p.Cys1371Gly Single submitter ⚠
- p.Cys1704Ser Single submitter ⚠
- p.Cys1969Phe Single submitter ⚠
- p.Cys2171Trp Single submitter CUL9-related disorder ⚠
- p.Cys2404Tyr Single submitter ⚠
- p.Cys47Gly Single submitter ⚠
- p.Gln1094Lys Single submitter ⚠
- p.Gln1309His Single submitter ⚠
- p.Gln1556Arg Single submitter ⚠
- p.Gln1598Lys Single submitter ⚠
- p.Gln2012Arg Single submitter ⚠
- p.Gln2061Arg Single submitter ⚠
- p.Gln211His Single submitter ⚠
- p.Gln339Arg Single submitter ⚠
- p.Gln384His Single submitter ⚠
- p.Glu1035Asp Single submitter ⚠
- p.Glu1052Lys Single submitter ⚠
- p.Glu109Lys Single submitter ⚠
- p.Glu1514Lys Single submitter ⚠
- p.Glu1579Gly Single submitter ⚠
- p.Glu1641Gly Single submitter ⚠
- p.Glu164Asp Single submitter ⚠
- p.Glu1689Gly Single submitter ⚠
- p.Glu2003Lys Single submitter ⚠
- p.Glu2020Lys Single submitter ⚠
- p.Glu2036Gln Single submitter ⚠
- p.Glu2247Lys Single submitter ⚠
- p.Glu23Gln Single submitter ⚠
- p.Glu2464Lys Single submitter ⚠
- p.Glu2470Asp Single submitter ⚠
- p.Glu312Gly Single submitter ⚠
- p.Glu403Asp Single submitter ⚠
- p.Glu545Lys Single submitter ⚠
- p.Glu606Gly Single submitter ⚠
- p.Glu624Lys Single submitter ⚠
- p.Glu92Ala Single submitter ⚠
- p.Gly1006Arg Single submitter ⚠
- p.Gly134Val Single submitter ⚠
- p.Gly1917Glu Single submitter ⚠
- p.Gly2126Arg Single submitter ⚠
- p.Gly213Asp Single submitter ⚠
- p.Gly213Val Single submitter ⚠
- p.Gly2178Arg Single submitter ⚠
- p.Gly2185Asp Single submitter ⚠
- p.Gly2213Ser Single submitter ⚠
- p.Gly282Arg Single submitter ⚠
- p.Gly438Asp Single submitter ⚠
- p.Gly454Arg Single submitter ⚠
- p.Gly474Trp Single submitter ⚠
- p.Gly902Arg Single submitter ⚠
- p.Gly943Cys Single submitter ⚠
- p.Gly95Ala Single submitter ⚠
- p.Gly975Asp Single submitter ⚠
- p.His1155Arg Single submitter ⚠
- p.His1427Tyr Single submitter ⚠
- p.His2032Tyr Single submitter ⚠
- p.His2259Arg Single submitter ⚠
- p.His717Asn Single submitter ⚠
- p.Ile1053Val Single submitter ⚠
- p.Ile1245Val Single submitter ⚠
- p.Ile1472Val Single submitter ⚠
- p.Ile155Met Single submitter ⚠
- p.Ile155Val Single submitter ⚠
- p.Ile1930Val Single submitter ⚠
- p.Ile2129Met Single submitter ⚠
- p.Ile2129Thr Single submitter ⚠
- p.Leu1153Ile Single submitter ⚠
- p.Leu1429Val Single submitter ⚠
- p.Leu1488Pro Single submitter ⚠
- p.Leu1618Pro Single submitter ⚠
- p.Leu1769Val Single submitter ⚠
- p.Leu1846Pro Single submitter ⚠
- p.Leu1931Met Single submitter ⚠
- p.Leu2019Ile Single submitter ⚠
- p.Leu2049Gln Single submitter ⚠
- p.Leu2111Trp Single submitter ⚠
- p.Leu737Met Single submitter ⚠
- p.Leu767Ile Single submitter ⚠
- p.Leu79Pro Single submitter ⚠
- p.Leu967Met Single submitter ⚠
- p.Leu984Ile Single submitter ⚠
- p.Leu999Val Single submitter ⚠
- p.Lys1657Asn Single submitter ⚠
- p.Lys1781Thr Single submitter ⚠
- p.Lys2256Asn Single submitter ⚠
- p.Lys2291Arg Single submitter ⚠
- p.Lys293Arg Single submitter ⚠
- p.Met1209Ile Single submitter ⚠
- p.Met1209Val Single submitter ⚠
- p.Met1746Ile Single submitter ⚠
- p.Met1997Arg Single submitter ⚠
- p.Met218Val Single submitter ⚠
- p.Met2449Ile Single submitter ⚠
- p.Met304Ile Single submitter ⚠
- p.Met328Ile Single submitter ⚠
- p.Met433Val Single submitter ⚠
- p.Met472Thr Single submitter ⚠
- p.Met543Leu Single submitter ⚠
- p.Met634Val Single submitter ⚠
- p.Met651Leu Single submitter ⚠
- p.Met910Val Single submitter ⚠
- p.Met919Leu Single submitter ⚠
- p.Phe1306Leu Single submitter ⚠
- p.Phe1487Leu Single submitter ⚠
- p.Phe1647Leu Single submitter ⚠
- p.Phe1724Leu Single submitter ⚠
- p.Pro1005Leu Single submitter ⚠
- p.Pro1026Ser Single submitter ⚠
- p.Pro1047Leu Single submitter ⚠
- p.Pro1179Ala Single submitter ⚠
- p.Pro1300Arg Single submitter ⚠
- p.Pro1386Ala Single submitter ⚠
- p.Pro1436Leu Single submitter ⚠
- p.Pro1436Ser Single submitter ⚠
- p.Pro1446Arg Single submitter ⚠
- p.Pro1495Arg Single submitter ⚠
- p.Pro1518Ser Single submitter ⚠
- p.Pro1742Gln Single submitter ⚠
- p.Pro1801Ser Single submitter ⚠
- p.Pro1959Leu Single submitter ⚠
- p.Pro1999Arg Single submitter ⚠
- p.Pro2046Arg Single submitter ⚠
- p.Pro2046His Single submitter ⚠
- p.Pro2116Leu Single submitter ⚠
- p.Pro2325Leu Single submitter ⚠
- p.Pro356Arg Single submitter ⚠
- p.Pro439Leu Single submitter ⚠
- p.Pro479Leu Single submitter ⚠
- p.Pro579Thr Single submitter ⚠
- p.Pro851Ser Single submitter ⚠
- p.Pro909Ser Single submitter ⚠
- p.Pro911Leu Single submitter Single umbilical artery ⚠
- p.Ser1385Phe Single submitter ⚠
- p.Ser1461Pro Single submitter ⚠
- p.Ser1513Ala Single submitter ⚠
- p.Ser1528Asn Single submitter ⚠
- p.Ser1610Leu Single submitter ⚠
- p.Ser1638Thr Single submitter ⚠
- p.Ser1696Cys Single submitter ⚠
- p.Ser1701Ala Single submitter ⚠
- p.Ser1732Phe Single submitter ⚠
- p.Ser1797Phe Single submitter ⚠
- p.Ser1800Phe Single submitter ⚠
- p.Ser1976Tyr Single submitter ⚠
- p.Ser2031Phe Single submitter ⚠
- p.Ser2075Gly Single submitter ⚠
- p.Ser2135Leu Single submitter ⚠
- p.Ser2155Cys Single submitter ⚠
- p.Ser2495Thr Single submitter ⚠
- p.Ser276Gly Single submitter ⚠
- p.Ser303Thr Single submitter ⚠
- p.Ser316Thr Single submitter ⚠
- p.Ser346Arg Single submitter ⚠
- p.Ser589Thr Single submitter ⚠
- p.Ser600Leu Single submitter ⚠
- p.Ser637Ile Single submitter ⚠
- p.Ser68Leu Single submitter ⚠
- p.Ser692Gly Single submitter ⚠
- p.Ser725Leu Single submitter ⚠
- p.Ser807Leu Single submitter ⚠
- p.Thr1186Met Single submitter ⚠
- p.Thr1206Ile Single submitter ⚠
- p.Thr1247Ala Single submitter ⚠
- p.Thr1251Lys Single submitter ⚠
- p.Thr1314Ala Single submitter ⚠
- p.Thr1384Ala Single submitter ⚠
- p.Thr1541Ile Single submitter ⚠