CYREN — 3 ClinVar variants
All ClinVar germline CYREN variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 1 flagged for review →
1 Benign · 1 Likely benign · 1 Uncertain significance
Full CYREN gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 1
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All CYREN variants
Benign 1
- p.Lys149= Multiple submitters
Likely benign 1
- p.Pro120Ala Single submitter
Uncertain significance 1
- p.Asp112His Single submitter ⚠