DAAM2 — 247 ClinVar variants

All ClinVar germline DAAM2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 186 flagged for review →

3 Pathogenic · 2 Likely pathogenic · 2 Conflicting · 20 Benign · 38 Likely benign · 182 Uncertain significance

Full DAAM2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 186

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors vs ClinVar 1

ClinVar calls these pathogenic, but the computational predictors lean tolerated — the highest-value review flag.

DAAM2 p.Glu121Gln Pathogenic No assertion criteria
nephrotic syndrome, type 24

Predictors agree, ClinVar conflicts 1

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

DAAM2 p.Ser1028Leu Conflicting Single submitter
nephrotic syndrome, type 24

Predictors lean, ClinVar uncertain 100

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

DAAM2 p.Arg335Trp Uncertain significance Multiple submitters
Inborn genetic diseases
DAAM2 p.Arg676Trp Uncertain significance Multiple submitters
Inborn genetic diseases
DAAM2 p.Gln760Arg Uncertain significance Multiple submitters
Inborn genetic diseases
DAAM2 p.Ile699Val Uncertain significance Multiple submitters
Inborn genetic diseases
DAAM2 p.Ala117Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala167Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala491Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala934Asp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1031His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1045Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1047Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1059Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1061Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg138Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg138Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg209Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg252Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg262Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg262Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg266Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg266Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg317Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg403Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg492Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg501Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg597Pro Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg633Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg738Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg791His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg814Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg814His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg903Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg972Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg981Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg987Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg988Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asn1064Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asn439Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp1024Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp446Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp727Tyr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp836Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp955Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp962His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Cys15Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Cys169Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gln864Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu131Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu641Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu714Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu735Lys Uncertain significance Single submitter
nephrotic syndrome, type 24
DAAM2 p.Glu926Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly1020Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly1033Ala Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly392Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly816Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly946Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly959Ala Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.His193Asp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.His233Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.His8Pro Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.His948Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile106Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile178Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile204Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile22Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile404Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile404Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile726Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile782Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu133Met Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu474Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu825Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu842Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu877Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Lys937Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Met456Ile Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Met943Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Phe549Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Phe938Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro198Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro522Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro860Ala Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro860Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro867Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro91Leu Uncertain significance Single submitter
DAAM2 p.Ser1016Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser1046Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser686Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser786Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser7Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Thr146Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Thr482Met Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Thr831Ala Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Thr963Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Val432Ile Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Val631Ile Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Val893Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala829Thr Uncertain significance No assertion criteria
DAAM2-related disorder
DAAM2 p.Gly527Val Uncertain significance No assertion criteria
DAAM2-related disorder

Predictors split 84

The independent predictors disagree with each other — read with care.

DAAM2 p.Arg990Cys Uncertain significance Multiple submitters
Inborn genetic diseases
DAAM2 p.Glu956Lys Uncertain significance Multiple submitters
Inborn genetic diseases
DAAM2 p.Pro74Thr Uncertain significance Multiple submitters
nephrotic syndrome, type 24
DAAM2 p.Ala247Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala775Pro Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala870Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ala989Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1001Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1001His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1003Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1008Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1047Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1049Pro Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1059Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg105Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1061Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1061Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg1065Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg162Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg172Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg28Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg403Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg445Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg4His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg4Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg51Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg665Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg696Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg741His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg794Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg886Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg900Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg972Trp Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg987Gln Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg990His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asn838His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp1037Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp412Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp419His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Asp639Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Cys383Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gln499His Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu413Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu449Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu466Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu470Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu496Gly Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu615Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu693Lys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Glu976Ala Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly392Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly563Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly564Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Gly578Cys Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.His319Tyr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.His350Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ile149Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu458Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu579Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Leu700Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Lys1044Asn Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Lys982Glu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Met348Val Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Met480Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Met978Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Met991Thr Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Phe70Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro542Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro543Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro548Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro566Leu Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro573Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Pro582His Conflicting Single submitter
nephrotic syndrome, type 24
DAAM2 p.Pro604Ser Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser114Arg Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser520Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Ser656Phe Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Thr918Met Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Thr963Ile Uncertain significance Single submitter
Inborn genetic diseases
DAAM2 p.Arg990Leu Likely benign No assertion criteria
DAAM2-related disorder
DAAM2 p.Glu997Lys Uncertain significance No assertion criteria
DAAM2-related disorder
DAAM2 p.Ile856Thr Likely benign No assertion criteria
DAAM2-related disorder
DAAM2 p.Lys776Thr Likely benign No assertion criteria
DAAM2-related disorder
DAAM2 p.Pro555Leu Likely benign No assertion criteria
DAAM2-related disorder

All DAAM2 variants

Pathogenic 3

p.Arg335Gln No assertion criteria nephrotic syndrome, type 24
p.Arg445Ter No assertion criteria nephrotic syndrome, type 24
p.Glu121Gln No assertion criteria nephrotic syndrome, type 24 ⚠

Likely pathogenic 2

p.Arg66Ter Single submitter nephrotic syndrome, type 24
p.Gly1020Ter Single submitter nephrotic syndrome, type 24

Conflicting classifications of pathogenicity 2

p.Pro582His Single submitter nephrotic syndrome, type 24 ⚠
p.Ser1028Leu Single submitter nephrotic syndrome, type 24 ⚠

Benign 20

c.2510+8C>T Single submitter
c.2983-8G>A Single submitter
c.429-10T>C Single submitter
p.Gly18Arg Single submitter
p.Pro573Leu Single submitter
c.2983-9C>T No assertion criteria DAAM2-related disorder
p.Ala869= No assertion criteria DAAM2-related disorder
p.Arg1059= No assertion criteria DAAM2-related disorder
p.Arg105His No assertion criteria DAAM2-related disorder
p.Arg172His No assertion criteria DAAM2-related disorder
p.Arg597His No assertion criteria DAAM2-related disorder
p.Arg617His No assertion criteria DAAM2-related disorder
p.Asn258= No assertion criteria DAAM2-related disorder
p.Asn932Ser No assertion criteria DAAM2-related disorder
p.Gln600Arg No assertion criteria DAAM2-related disorder
p.His9= No assertion criteria DAAM2-related disorder
p.Ile660= No assertion criteria DAAM2-related disorder
p.Ile828= No assertion criteria DAAM2-related disorder
p.Lys642= No assertion criteria DAAM2-related disorder
p.Val245Leu No assertion criteria DAAM2-related disorder

Likely benign 38

c.258+31C>T Single submitter
c.2983-21T>G Single submitter
c.*2409G>T Single submitter sulfite oxidase deficiency due to molybdenum cofactor deficiency type A
p.Ala45Thr Single submitter Inborn genetic diseases
p.Arg414Gln Single submitter
p.Arg597Cys Single submitter Inborn genetic diseases
p.Arg886= Single submitter
p.Gln447Glu Single submitter
p.Glu894= Single submitter Inborn genetic diseases
p.Phe17= Single submitter
p.Pro3Ser Single submitter Inborn genetic diseases
p.Val591Ile Single submitter Inborn genetic diseases
c.1845+7A>G No assertion criteria DAAM2-related disorder
c.2342-10C>T No assertion criteria DAAM2-related disorder
c.2982+10_2982+34del No assertion criteria DAAM2-related disorder
c.2983-4G>A No assertion criteria DAAM2-related disorder
c.2983-8G>C No assertion criteria DAAM2-related disorder
p.Ala1054Thr No assertion criteria DAAM2-related disorder
p.Arg633= No assertion criteria DAAM2-related disorder
p.Arg990Leu No assertion criteria DAAM2-related disorder ⚠
p.Asn44= No assertion criteria DAAM2-related disorder
p.Asp753Gly No assertion criteria DAAM2-related disorder
p.Gly527= No assertion criteria DAAM2-related disorder
p.Gly887= No assertion criteria DAAM2-related disorder
p.Ile856Thr No assertion criteria DAAM2-related disorder ⚠
p.Leu401= No assertion criteria DAAM2-related disorder
p.Leu579= No assertion criteria DAAM2-related disorder
p.Lys776Thr No assertion criteria DAAM2-related disorder ⚠
p.Phe331= No assertion criteria DAAM2-related disorder
p.Phe938= No assertion criteria DAAM2-related disorder
p.Pro3= No assertion criteria DAAM2-related disorder
p.Pro43= No assertion criteria DAAM2-related disorder
p.Pro555Leu No assertion criteria DAAM2-related disorder ⚠
p.Pro556= No assertion criteria DAAM2-related disorder
p.Ser279Phe No assertion criteria DAAM2-related disorder
p.Ser914= No assertion criteria DAAM2-related disorder
p.Ser925= No assertion criteria DAAM2-related disorder
p.Thr123= No assertion criteria DAAM2-related disorder

Uncertain significance 182

p.Arg335Trp Multiple submitters Inborn genetic diseases ⚠
p.Arg676Trp Multiple submitters Inborn genetic diseases ⚠
p.Arg990Cys Multiple submitters Inborn genetic diseases ⚠
p.Gln760Arg Multiple submitters Inborn genetic diseases ⚠
p.Glu956Lys Multiple submitters Inborn genetic diseases ⚠
p.Ile699Val Multiple submitters Inborn genetic diseases ⚠
p.Pro74Thr Multiple submitters nephrotic syndrome, type 24 ⚠
c.2252+5G>C Single submitter
c.2812-4A>C Single submitter
p.Ala117Val Single submitter Inborn genetic diseases ⚠
p.Ala167Thr Single submitter Inborn genetic diseases ⚠
p.Ala247Val Single submitter Inborn genetic diseases ⚠
p.Ala491Gly Single submitter Inborn genetic diseases ⚠
p.Ala775Pro Single submitter Inborn genetic diseases ⚠
p.Ala870Thr Single submitter Inborn genetic diseases ⚠
p.Ala934Asp Single submitter Inborn genetic diseases ⚠
p.Ala989Val Single submitter Inborn genetic diseases ⚠
p.Arg1001Cys Single submitter Inborn genetic diseases ⚠
p.Arg1001His Single submitter Inborn genetic diseases ⚠
p.Arg1003Trp Single submitter Inborn genetic diseases ⚠
p.Arg1008Trp Single submitter Inborn genetic diseases ⚠
p.Arg1031His Single submitter Inborn genetic diseases ⚠
p.Arg1045Cys Single submitter Inborn genetic diseases ⚠
p.Arg1047Cys Single submitter Inborn genetic diseases ⚠
p.Arg1047Ser Single submitter Inborn genetic diseases ⚠
p.Arg1049Pro Single submitter Inborn genetic diseases ⚠
p.Arg1059Gln Single submitter Inborn genetic diseases ⚠
p.Arg1059Trp Single submitter Inborn genetic diseases ⚠
p.Arg105Cys Single submitter Inborn genetic diseases ⚠
p.Arg1061Gln Single submitter Inborn genetic diseases ⚠
p.Arg1061Leu Single submitter Inborn genetic diseases ⚠
p.Arg1061Trp Single submitter Inborn genetic diseases ⚠
p.Arg1065Gln Single submitter Inborn genetic diseases ⚠
p.Arg138Gln Single submitter Inborn genetic diseases ⚠
p.Arg138Trp Single submitter Inborn genetic diseases ⚠
p.Arg162Trp Single submitter Inborn genetic diseases ⚠
p.Arg172Cys Single submitter Inborn genetic diseases ⚠
p.Arg209Gly Single submitter Inborn genetic diseases ⚠
p.Arg252Cys Single submitter Inborn genetic diseases ⚠
p.Arg262Gln Single submitter Inborn genetic diseases ⚠
p.Arg262Gly Single submitter Inborn genetic diseases ⚠
p.Arg266Gln Single submitter Inborn genetic diseases ⚠
p.Arg266Leu Single submitter Inborn genetic diseases ⚠
p.Arg28Trp Single submitter Inborn genetic diseases ⚠
p.Arg317Trp Single submitter Inborn genetic diseases ⚠
p.Arg403Cys Single submitter Inborn genetic diseases ⚠
p.Arg403Gly Single submitter Inborn genetic diseases ⚠
p.Arg445Gln Single submitter Inborn genetic diseases ⚠
p.Arg492Gln Single submitter Inborn genetic diseases ⚠
p.Arg4His Single submitter Inborn genetic diseases ⚠
p.Arg4Leu Single submitter Inborn genetic diseases ⚠
p.Arg501Gln Single submitter Inborn genetic diseases ⚠
p.Arg51Cys Single submitter Inborn genetic diseases ⚠
p.Arg597Pro Single submitter Inborn genetic diseases ⚠
p.Arg633Gln Single submitter Inborn genetic diseases ⚠
p.Arg665Cys Single submitter Inborn genetic diseases ⚠
p.Arg696Gln Single submitter Inborn genetic diseases ⚠
p.Arg738Trp Single submitter Inborn genetic diseases ⚠
p.Arg741His Single submitter Inborn genetic diseases ⚠
p.Arg791His Single submitter Inborn genetic diseases ⚠
p.Arg794Cys Single submitter Inborn genetic diseases ⚠
p.Arg814Cys Single submitter Inborn genetic diseases ⚠
p.Arg814His Single submitter Inborn genetic diseases ⚠
p.Arg886Ser Single submitter Inborn genetic diseases ⚠
p.Arg900Cys Single submitter Inborn genetic diseases ⚠
p.Arg903Gln Single submitter Inborn genetic diseases ⚠
p.Arg972Gln Single submitter Inborn genetic diseases ⚠
p.Arg972Trp Single submitter Inborn genetic diseases ⚠
p.Arg981Lys Single submitter Inborn genetic diseases ⚠
p.Arg987Gln Single submitter Inborn genetic diseases ⚠
p.Arg987Trp Single submitter Inborn genetic diseases ⚠
p.Arg988Trp Single submitter Inborn genetic diseases ⚠
p.Arg990His Single submitter Inborn genetic diseases ⚠
p.Asn1064Lys Single submitter Inborn genetic diseases ⚠
p.Asn439Ser Single submitter Inborn genetic diseases ⚠
p.Asn838His Single submitter Inborn genetic diseases ⚠
p.Asp1024Asn Single submitter Inborn genetic diseases ⚠
p.Asp1037Asn Single submitter Inborn genetic diseases ⚠
p.Asp412Glu Single submitter Inborn genetic diseases ⚠
p.Asp419His Single submitter Inborn genetic diseases ⚠
p.Asp446Glu Single submitter Inborn genetic diseases ⚠
p.Asp639Gly Single submitter Inborn genetic diseases ⚠
p.Asp727Tyr Single submitter Inborn genetic diseases ⚠
p.Asp836Asn Single submitter Inborn genetic diseases ⚠
p.Asp955Glu Single submitter Inborn genetic diseases ⚠
p.Asp962His Single submitter Inborn genetic diseases ⚠
p.Cys15Trp Single submitter Inborn genetic diseases ⚠
p.Cys169Ser Single submitter Inborn genetic diseases ⚠
p.Cys383Phe Single submitter Inborn genetic diseases ⚠
p.Gln499His Single submitter Inborn genetic diseases ⚠
p.Gln864Arg Single submitter Inborn genetic diseases ⚠
p.Glu131Lys Single submitter Inborn genetic diseases ⚠
p.Glu413Lys Single submitter Inborn genetic diseases ⚠
p.Glu449Lys Single submitter Inborn genetic diseases ⚠
p.Glu466Gly Single submitter Inborn genetic diseases ⚠
p.Glu470Lys Single submitter Inborn genetic diseases ⚠
p.Glu496Gly Single submitter Inborn genetic diseases ⚠
p.Glu615Lys Single submitter Inborn genetic diseases ⚠
p.Glu641Lys Single submitter Inborn genetic diseases ⚠
p.Glu693Lys Single submitter Inborn genetic diseases ⚠
p.Glu714Gln Single submitter Inborn genetic diseases ⚠
p.Glu735Lys Single submitter nephrotic syndrome, type 24 ⚠
p.Glu926Lys Single submitter Inborn genetic diseases ⚠
p.Glu976Ala Single submitter Inborn genetic diseases ⚠
p.Gly1020Glu Single submitter Inborn genetic diseases ⚠
p.Gly1033Ala Single submitter Inborn genetic diseases ⚠
p.Gly392Arg Single submitter Inborn genetic diseases ⚠
p.Gly392Ser Single submitter Inborn genetic diseases ⚠
p.Gly563Arg Single submitter Inborn genetic diseases ⚠
p.Gly564Glu Single submitter Inborn genetic diseases ⚠
p.Gly578Cys Single submitter Inborn genetic diseases ⚠
p.Gly816Ser Single submitter Inborn genetic diseases ⚠
p.Gly946Arg Single submitter Inborn genetic diseases ⚠
p.Gly959Ala Single submitter Inborn genetic diseases ⚠
p.His193Asp Single submitter Inborn genetic diseases ⚠
p.His233Gln Single submitter Inborn genetic diseases ⚠
p.His319Tyr Single submitter Inborn genetic diseases ⚠
p.His350Leu Single submitter Inborn genetic diseases ⚠
p.His8Pro Single submitter Inborn genetic diseases ⚠
p.His948Asn Single submitter Inborn genetic diseases ⚠
p.Ile106Phe Single submitter Inborn genetic diseases ⚠
p.Ile149Thr Single submitter Inborn genetic diseases ⚠
p.Ile178Thr Single submitter Inborn genetic diseases ⚠
p.Ile204Thr Single submitter Inborn genetic diseases ⚠
p.Ile22Val Single submitter Inborn genetic diseases ⚠
p.Ile404Thr Single submitter Inborn genetic diseases ⚠
p.Ile404Val Single submitter Inborn genetic diseases ⚠
p.Ile726Val Single submitter Inborn genetic diseases ⚠
p.Ile782Thr Single submitter Inborn genetic diseases ⚠
p.Leu133Met Single submitter Inborn genetic diseases ⚠
p.Leu458Phe Single submitter Inborn genetic diseases ⚠
p.Leu474Ser Single submitter Inborn genetic diseases ⚠
p.Leu579Arg Single submitter Inborn genetic diseases ⚠
p.Leu700Phe Single submitter Inborn genetic diseases ⚠
p.Leu825Phe Single submitter Inborn genetic diseases ⚠
p.Leu842Phe Single submitter Inborn genetic diseases ⚠
p.Leu877Gln Single submitter Inborn genetic diseases ⚠
p.Lys1044Asn Single submitter Inborn genetic diseases ⚠
p.Lys937Glu Single submitter Inborn genetic diseases ⚠
p.Lys982fs Single submitter nephrotic syndrome, type 24
p.Lys982Glu Single submitter Inborn genetic diseases ⚠
p.Met348Val Single submitter Inborn genetic diseases ⚠
p.Met456Ile Single submitter Inborn genetic diseases ⚠
p.Met480Thr Single submitter Inborn genetic diseases ⚠
p.Met943Arg Single submitter Inborn genetic diseases ⚠
p.Met978Thr Single submitter Inborn genetic diseases ⚠
p.Met991Thr Single submitter Inborn genetic diseases ⚠
p.Phe549Leu Single submitter Inborn genetic diseases ⚠
p.Phe70Leu Single submitter Inborn genetic diseases ⚠
p.Phe938Cys Single submitter Inborn genetic diseases ⚠
p.Pro198Ser Single submitter Inborn genetic diseases ⚠
p.Pro522Ser Single submitter Inborn genetic diseases ⚠
p.Pro542Leu Single submitter Inborn genetic diseases ⚠
p.Pro543Leu Single submitter Inborn genetic diseases ⚠
p.Pro548Leu Single submitter Inborn genetic diseases ⚠
p.Pro566Leu Single submitter Inborn genetic diseases ⚠
p.Pro573Ser Single submitter Inborn genetic diseases ⚠
p.Pro604Ser Single submitter Inborn genetic diseases ⚠
p.Pro860Ala Single submitter Inborn genetic diseases ⚠
p.Pro860Ser Single submitter Inborn genetic diseases ⚠
p.Pro867Ser Single submitter Inborn genetic diseases ⚠
p.Pro91Leu Single submitter ⚠
p.Ser1016Leu Single submitter Inborn genetic diseases ⚠
p.Ser1046Asn Single submitter Inborn genetic diseases ⚠
p.Ser114Arg Single submitter Inborn genetic diseases ⚠
p.Ser520Phe Single submitter Inborn genetic diseases ⚠
p.Ser656Phe Single submitter Inborn genetic diseases ⚠
p.Ser686Phe Single submitter Inborn genetic diseases ⚠
p.Ser786Phe Single submitter Inborn genetic diseases ⚠
p.Ser7Asn Single submitter Inborn genetic diseases ⚠
p.Thr146Asn Single submitter Inborn genetic diseases ⚠
p.Thr482Met Single submitter Inborn genetic diseases ⚠
p.Thr831Ala Single submitter Inborn genetic diseases ⚠
p.Thr918Met Single submitter Inborn genetic diseases ⚠
p.Thr963Asn Single submitter Inborn genetic diseases ⚠
p.Thr963Ile Single submitter Inborn genetic diseases ⚠
p.Val432Ile Single submitter Inborn genetic diseases ⚠
p.Val631Ile Single submitter Inborn genetic diseases ⚠
p.Val893Leu Single submitter Inborn genetic diseases ⚠
p.Ala829Thr No assertion criteria DAAM2-related disorder ⚠
p.Glu997Lys No assertion criteria DAAM2-related disorder ⚠
p.Gly527Val No assertion criteria DAAM2-related disorder ⚠