DCUN1D3 — 31 ClinVar variants
All ClinVar germline DCUN1D3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 31 flagged for review →
31 Uncertain significance
Full DCUN1D3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 31
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 19
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DCUN1D3 p.Ala65Asp Uncertain significance Single submitter
- DCUN1D3 p.Arg102Gln Uncertain significance Single submitter
- DCUN1D3 p.Arg165Gln Uncertain significance Single submitter
- DCUN1D3 p.Arg240Trp Uncertain significance Single submitter
- DCUN1D3 p.Arg283Thr Uncertain significance Single submitter
- DCUN1D3 p.Arg288Gly Uncertain significance Single submitter
- DCUN1D3 p.Arg77Lys Uncertain significance Single submitter
- DCUN1D3 p.Arg96Met Uncertain significance Single submitter
- DCUN1D3 p.Asn217Ser Uncertain significance Single submitter
- DCUN1D3 p.Asp149Asn Uncertain significance Single submitter
- DCUN1D3 p.Asp192Tyr Uncertain significance Single submitter
- DCUN1D3 p.Gln215His Uncertain significance Single submitter
- DCUN1D3 p.Glu60Lys Uncertain significance Single submitter
- DCUN1D3 p.Gly48Asp Uncertain significance Single submitter
- DCUN1D3 p.His29Arg Uncertain significance Single submitter
- DCUN1D3 p.Ile51Thr Uncertain significance Single submitter
- DCUN1D3 p.Lys236Arg Uncertain significance Single submitter
- DCUN1D3 p.Pro24Leu Uncertain significance Single submitter
- DCUN1D3 p.Val53Ile Uncertain significance Single submitter
Predictors split 12
The independent predictors disagree with each other — read with care.
- DCUN1D3 p.Arg184Gln Uncertain significance Single submitter
- DCUN1D3 p.Arg22His Uncertain significance Single submitter
- DCUN1D3 p.Arg37Cys Uncertain significance Single submitter
- DCUN1D3 p.Arg90Ser Uncertain significance Single submitter
- DCUN1D3 p.Arg97Cys Uncertain significance Single submitter
- DCUN1D3 p.Arg97His Uncertain significance Single submitter
- DCUN1D3 p.Gln89Pro Uncertain significance Single submitter
- DCUN1D3 p.Gly55Arg Uncertain significance Single submitter
- DCUN1D3 p.Ile154Val Uncertain significance Single submitter
- DCUN1D3 p.Leu269Ile Uncertain significance Single submitter
- DCUN1D3 p.Thr229Ile Uncertain significance Single submitter
- DCUN1D3 p.Thr70Met Uncertain significance Single submitter
All DCUN1D3 variants
Uncertain significance 31
- p.Ala65Asp Single submitter ⚠
- p.Arg102Gln Single submitter ⚠
- p.Arg165Gln Single submitter ⚠
- p.Arg184Gln Single submitter ⚠
- p.Arg22His Single submitter ⚠
- p.Arg240Trp Single submitter ⚠
- p.Arg283Thr Single submitter ⚠
- p.Arg288Gly Single submitter ⚠
- p.Arg37Cys Single submitter ⚠
- p.Arg77Lys Single submitter ⚠
- p.Arg90Ser Single submitter ⚠
- p.Arg96Met Single submitter ⚠
- p.Arg97Cys Single submitter ⚠
- p.Arg97His Single submitter ⚠
- p.Asn217Ser Single submitter ⚠
- p.Asp149Asn Single submitter ⚠
- p.Asp192Tyr Single submitter ⚠
- p.Gln215His Single submitter ⚠
- p.Gln89Pro Single submitter ⚠
- p.Glu60Lys Single submitter ⚠
- p.Gly48Asp Single submitter ⚠
- p.Gly55Arg Single submitter ⚠
- p.His29Arg Single submitter ⚠
- p.Ile154Val Single submitter ⚠
- p.Ile51Thr Single submitter ⚠
- p.Leu269Ile Single submitter ⚠
- p.Lys236Arg Single submitter ⚠
- p.Pro24Leu Single submitter ⚠
- p.Thr229Ile Single submitter ⚠
- p.Thr70Met Single submitter ⚠
- p.Val53Ile Single submitter ⚠