DLGAP3 — 12 ClinVar variants
All ClinVar germline DLGAP3 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 3 flagged for review →
5 Benign · 1 Benign/Likely benign · 5 Likely benign · 1 Uncertain significance
Full DLGAP3 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 3
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors split 3
The independent predictors disagree with each other — read with care.
All DLGAP3 variants
Benign 5
Benign/Likely benign 1
- p.Ser406= Multiple submitters
Likely benign 5
- p.Ala347= Single submitter
- p.Gly85_Ser86insTer Single submitter
- p.Pro45His Single submitter ⚠
- p.Pro45Thr Single submitter ⚠
- p.Val886= Single submitter
Uncertain significance 1
- p.Lys889Arg Single submitter ⚠