DMBT1 — 464 ClinVar variants
All ClinVar germline DMBT1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 359 flagged for review →
17 Benign · 2 Benign/Likely benign · 112 Likely benign · 333 Uncertain significance
Full DMBT1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 359
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 127
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DMBT1 p.Asp696Val Uncertain significance Multiple submitters
- DMBT1 p.Ala101Val Uncertain significance Single submitter
- DMBT1 p.Ala1027Asp Uncertain significance Single submitter
- DMBT1 p.Ala1088Thr Uncertain significance Single submitter
- DMBT1 p.Ala2025Thr Uncertain significance Single submitter
- DMBT1 p.Ala2161Ser Uncertain significance Single submitter
- DMBT1 p.Ala2329Val Uncertain significance Single submitter
- DMBT1 p.Arg1032Gly Uncertain significance Single submitter
- DMBT1 p.Arg2027Cys Uncertain significance Single submitter
- DMBT1 p.Arg2201Ser Uncertain significance Single submitter
- DMBT1 p.Arg2236Ser Uncertain significance Single submitter
- DMBT1 p.Arg2467His Uncertain significance Single submitter
- DMBT1 p.Arg246Gln Uncertain significance Single submitter
- DMBT1 p.Arg2481Leu Uncertain significance Single submitter
- DMBT1 p.Arg2502Leu Uncertain significance Single submitter
- DMBT1 p.Arg2537Gln Uncertain significance Single submitter
- DMBT1 p.Arg339Trp Uncertain significance Single submitter
- DMBT1 p.Arg614Leu Uncertain significance Single submitter
- DMBT1 p.Arg711Ser Uncertain significance Single submitter
- DMBT1 p.Asn1025Ser Uncertain significance Single submitter
- DMBT1 p.Asn1726Ser Uncertain significance Single submitter
- DMBT1 p.Asn1939Ser Uncertain significance Single submitter
- DMBT1 p.Asn1961Ser Uncertain significance Single submitter
- DMBT1 p.Asn2249Tyr Uncertain significance Single submitter
- DMBT1 p.Asn2317Ser Uncertain significance Single submitter
- DMBT1 p.Asn266Ser Uncertain significance Single submitter
- DMBT1 p.Asn634Ser Uncertain significance Single submitter
- DMBT1 p.Asn684Ser Uncertain significance Single submitter
- DMBT1 p.Asp1188Val Uncertain significance Single submitter
- DMBT1 p.Asp132His Uncertain significance Single submitter
- DMBT1 p.Asp1879Val Uncertain significance Single submitter
- DMBT1 p.Asp1972Glu Uncertain significance Single submitter
- DMBT1 p.Cys1036Phe Uncertain significance Single submitter
- DMBT1 p.Cys1676Arg Uncertain significance Single submitter
- DMBT1 p.Cys1727Phe Uncertain significance Single submitter
- DMBT1 p.Cys1921Arg Uncertain significance Single submitter
- DMBT1 p.Cys2291Arg Uncertain significance Single submitter
- DMBT1 p.Gln1033His Uncertain significance Single submitter
- DMBT1 p.Gln2047Arg Uncertain significance Single submitter
- DMBT1 p.Gln2530Arg Uncertain significance Single submitter
- DMBT1 p.Gln288Pro Uncertain significance Single submitter
- DMBT1 p.Glu1066Lys Uncertain significance Single submitter
- DMBT1 p.Glu1926Gln Uncertain significance Single submitter
- DMBT1 p.Glu2242Gln Uncertain significance Single submitter
- DMBT1 p.Glu327Ala Uncertain significance Single submitter
- DMBT1 p.Glu747Gln Uncertain significance Single submitter
- DMBT1 p.Gly1015Asp Uncertain significance Single submitter
- DMBT1 p.Gly1051Asp Uncertain significance Single submitter
- DMBT1 p.Gly1064Arg Uncertain significance Single submitter
- DMBT1 p.Gly107Val Uncertain significance Single submitter
- DMBT1 p.Gly160Asp Uncertain significance Single submitter
- DMBT1 p.Gly1660Asp Uncertain significance Single submitter
- DMBT1 p.Gly1660Ser Uncertain significance Single submitter
- DMBT1 p.Gly1709Glu Uncertain significance Single submitter
- DMBT1 p.Gly1780Val Uncertain significance Single submitter
- DMBT1 p.Gly1791Arg Uncertain significance Single submitter
- DMBT1 p.Gly1825Asp Uncertain significance Single submitter
- DMBT1 p.Gly194Arg Uncertain significance Single submitter
- DMBT1 p.Gly2071Arg Uncertain significance Single submitter
- DMBT1 p.Gly2086Val Uncertain significance Single submitter
- DMBT1 p.Gly2155Arg Uncertain significance Single submitter
- DMBT1 p.Gly256Asp Uncertain significance Single submitter
- DMBT1 p.Gly292Asp Uncertain significance Single submitter
- DMBT1 p.Gly292Val Uncertain significance Single submitter
- DMBT1 p.Gly590Asp Uncertain significance Single submitter
-
DMBT1 p.Gly673Glu
Uncertain significance
Single submitter
hereditary breast ovarian cancer syndrome
- DMBT1 p.Gly804Val Uncertain significance Single submitter
- DMBT1 p.Gly99Arg Uncertain significance Single submitter
- DMBT1 p.Gly99Ser Uncertain significance Single submitter
- DMBT1 p.His1065Arg Uncertain significance Single submitter
- DMBT1 p.His1065Asn Uncertain significance Single submitter
- DMBT1 p.His2032Arg Uncertain significance Single submitter
- DMBT1 p.His2118Arg Uncertain significance Single submitter
- DMBT1 p.His2344Gln Uncertain significance Single submitter
- DMBT1 p.His2366Gln Uncertain significance Single submitter
- DMBT1 p.His694Tyr Uncertain significance Single submitter
- DMBT1 p.Ile2046Val Uncertain significance Single submitter
- DMBT1 p.Ile2167Thr Uncertain significance Single submitter
- DMBT1 p.Ile2282Asn Uncertain significance Single submitter
- DMBT1 p.Ile2334Thr Uncertain significance Single submitter
- DMBT1 p.Ile2360Val Uncertain significance Single submitter
- DMBT1 p.Ile795Leu Uncertain significance Single submitter
- DMBT1 p.Leu995Pro Uncertain significance Single submitter
- DMBT1 p.Lys2521Asn Uncertain significance Single submitter
- DMBT1 p.Met2349Val Uncertain significance Single submitter
- DMBT1 p.Phe1693Leu Uncertain significance Single submitter
- DMBT1 p.Pro222Ser Uncertain significance Single submitter
- DMBT1 p.Pro2297Ala Uncertain significance Single submitter
- DMBT1 p.Pro2534Thr Uncertain significance Single submitter
- DMBT1 p.Pro2535Gln Uncertain significance Single submitter
- DMBT1 p.Pro2541Ser Uncertain significance Single submitter
- DMBT1 p.Pro596Ser Uncertain significance Single submitter
- DMBT1 p.Ser1079Thr Uncertain significance Single submitter
- DMBT1 p.Ser1085Arg Uncertain significance Single submitter
- DMBT1 p.Ser1085Asn Uncertain significance Single submitter
- DMBT1 p.Ser1116Pro Uncertain significance Single submitter
- DMBT1 p.Ser1724Thr Uncertain significance Single submitter
- DMBT1 p.Ser1959Leu Uncertain significance Single submitter
- DMBT1 p.Ser2005Thr Uncertain significance Single submitter
- DMBT1 p.Ser2278Cys Uncertain significance Single submitter
- DMBT1 p.Ser2442Pro Uncertain significance Single submitter
- DMBT1 p.Ser716Thr Uncertain significance Single submitter
- DMBT1 p.Ser739Asn Uncertain significance Single submitter
- DMBT1 p.Thr1635Ala Uncertain significance Single submitter
- DMBT1 p.Thr1876Ala Uncertain significance Single submitter
- DMBT1 p.Thr2038Ile Uncertain significance Single submitter
- DMBT1 p.Thr2533Asn Uncertain significance Single submitter
- DMBT1 p.Thr257Asn Uncertain significance Single submitter
- DMBT1 p.Tyr1981His Uncertain significance Single submitter
- DMBT1 p.Tyr2243Cys Uncertain significance Single submitter
- DMBT1 p.Tyr2269Cys Uncertain significance Single submitter
- DMBT1 p.Tyr2389Cys Uncertain significance Single submitter
- DMBT1 p.Val1006Leu Uncertain significance Single submitter
- DMBT1 p.Val1017Met Uncertain significance Single submitter
- DMBT1 p.Val1030Ile Uncertain significance Single submitter
- DMBT1 p.Val1135Met Uncertain significance Single submitter
- DMBT1 p.Val1662Met Uncertain significance Single submitter
- DMBT1 p.Val1784Gly Uncertain significance Single submitter
- DMBT1 p.Val1922Ile Uncertain significance Single submitter
- DMBT1 p.Val2281Phe Uncertain significance Single submitter
- DMBT1 p.Val2345Ile Uncertain significance Single submitter
- DMBT1 p.Val2367Ile Uncertain significance Single submitter
- DMBT1 p.Val2492Glu Uncertain significance Single submitter
- DMBT1 p.Val2508Leu Uncertain significance Single submitter
- DMBT1 p.Val518Met Uncertain significance Single submitter
- DMBT1 p.Val561Met Uncertain significance Single submitter
- DMBT1 p.Val615Met Uncertain significance Single submitter
Predictors split 232
The independent predictors disagree with each other — read with care. · showing the 150 best-reviewed of 232
- DMBT1 p.Arg670Cys Benign Multiple submitters
- DMBT1 p.Asp1796Glu Benign Multiple submitters
- DMBT1 p.Asp635Asn Benign Multiple submitters
- DMBT1 p.Asp668Asn Benign Multiple submitters
- DMBT1 p.His805Asn Uncertain significance Multiple submitters
- DMBT1 p.Ala1094Val Uncertain significance Single submitter
- DMBT1 p.Ala1630Ser Uncertain significance Single submitter
- DMBT1 p.Ala1687Val Uncertain significance Single submitter
- DMBT1 p.Ala483Glu Uncertain significance Single submitter
- DMBT1 p.Ala483Ser Uncertain significance Single submitter
- DMBT1 p.Ala543Pro Uncertain significance Single submitter
- DMBT1 p.Ala543Val Uncertain significance Single submitter
- DMBT1 p.Ala601Val Uncertain significance Single submitter
- DMBT1 p.Ala992Thr Uncertain significance Single submitter
- DMBT1 p.Arg1032Lys Uncertain significance Single submitter
- DMBT1 p.Arg1047Gln Uncertain significance Single submitter
- DMBT1 p.Arg1047Pro Uncertain significance Single submitter
- DMBT1 p.Arg1047Trp Uncertain significance Single submitter
- DMBT1 p.Arg1098Trp Uncertain significance Single submitter
- DMBT1 p.Arg1134Gln Uncertain significance Single submitter
- DMBT1 p.Arg1140Gln Likely benign Single submitter
- DMBT1 p.Arg1140Gly Likely benign Single submitter
- DMBT1 p.Arg1176Gln Uncertain significance Single submitter
- DMBT1 p.Arg1190Cys Uncertain significance Single submitter
- DMBT1 p.Arg1626Cys Uncertain significance Single submitter
- DMBT1 p.Arg1706Cys Uncertain significance Single submitter
- DMBT1 p.Arg1706His Uncertain significance Single submitter
- DMBT1 p.Arg170His Uncertain significance Single submitter
- DMBT1 p.Arg1823Pro Uncertain significance Single submitter
- DMBT1 p.Arg1837Cys Uncertain significance Single submitter
- DMBT1 p.Arg1837His Uncertain significance Single submitter
- DMBT1 p.Arg1932Cys Uncertain significance Single submitter
- DMBT1 p.Arg1932His Uncertain significance Single submitter
- DMBT1 p.Arg2013Trp Uncertain significance Single submitter
- DMBT1 p.Arg2060His Uncertain significance Single submitter
- DMBT1 p.Arg2095Trp Uncertain significance Single submitter
- DMBT1 p.Arg2107Cys Uncertain significance Single submitter
- DMBT1 p.Arg2130Cys Uncertain significance Single submitter
- DMBT1 p.Arg2201Cys Uncertain significance Single submitter
- DMBT1 p.Arg2208Gln Uncertain significance Single submitter
- DMBT1 p.Arg2227His Uncertain significance Single submitter
- DMBT1 p.Arg2240Trp Uncertain significance Single submitter
- DMBT1 p.Arg2292Trp Uncertain significance Single submitter
- DMBT1 p.Arg2342Cys Likely benign Single submitter
- DMBT1 p.Arg2342His Likely benign Single submitter
- DMBT1 p.Arg242Gly Uncertain significance Single submitter
- DMBT1 p.Arg2449Gln Uncertain significance Single submitter
- DMBT1 p.Arg2449Trp Uncertain significance Single submitter
- DMBT1 p.Arg2472Gln Uncertain significance Single submitter
- DMBT1 p.Arg2502His Uncertain significance Single submitter
- DMBT1 p.Arg252Gln Likely benign Single submitter
- DMBT1 p.Arg302Cys Uncertain significance Single submitter
- DMBT1 p.Arg302His Uncertain significance Single submitter
- DMBT1 p.Arg339Gln Likely benign Single submitter
- DMBT1 p.Arg495Lys Uncertain significance Single submitter
- DMBT1 p.Arg502Ser Uncertain significance Single submitter
- DMBT1 p.Arg512Gln Likely benign Single submitter
- DMBT1 p.Arg548Gln Uncertain significance Single submitter
- DMBT1 p.Arg562Cys Uncertain significance Single submitter
- DMBT1 p.Arg562His Uncertain significance Single submitter
- DMBT1 p.Arg610Gly Uncertain significance Single submitter
- DMBT1 p.Arg614Gln Likely benign Single submitter
- DMBT1 p.Arg670His Uncertain significance Single submitter
- DMBT1 p.Arg787Trp Uncertain significance Single submitter
- DMBT1 p.Arg801Cys Uncertain significance Single submitter
- DMBT1 p.Asn1028His Uncertain significance Single submitter
- DMBT1 p.Asn1045Ile Uncertain significance Single submitter
- DMBT1 p.Asn1081Asp Uncertain significance Single submitter
- DMBT1 p.Asn1642Lys Uncertain significance Single submitter
- DMBT1 p.Asn1673Ser Uncertain significance Single submitter
- DMBT1 p.Asn1773Ser Uncertain significance Single submitter
- DMBT1 p.Asn1801Ser Uncertain significance Single submitter
- DMBT1 p.Asn269Ser Uncertain significance Single submitter
- DMBT1 p.Asn286Ser Likely benign Single submitter
- DMBT1 p.Asn316Ser Uncertain significance Single submitter
- DMBT1 p.Asn546Ser Likely benign Single submitter
- DMBT1 p.Asn815Asp Uncertain significance Single submitter
- DMBT1 p.Asp1000Glu Uncertain significance Single submitter
- DMBT1 p.Asp1620Gly Uncertain significance Single submitter
- DMBT1 p.Asp1645Val Uncertain significance Single submitter
- DMBT1 p.Asp1665Asn Uncertain significance Single submitter
- DMBT1 p.Asp1802Glu Uncertain significance Single submitter
- DMBT1 p.Asp2081Tyr Uncertain significance Single submitter
- DMBT1 p.Asp2081Val Uncertain significance Single submitter
- DMBT1 p.Asp2197Asn Uncertain significance Single submitter
- DMBT1 p.Asp264Glu Uncertain significance Single submitter
- DMBT1 p.Asp559Asn Uncertain significance Single submitter
- DMBT1 p.Asp560Asn Uncertain significance Single submitter
- DMBT1 p.Asp973Gly Uncertain significance Single submitter
- DMBT1 p.Gln1096His Uncertain significance Single submitter
- DMBT1 p.Gln1695Leu Uncertain significance Single submitter
- DMBT1 p.Gln2409Glu Uncertain significance Single submitter
- DMBT1 p.Gln743His Uncertain significance Single submitter
- DMBT1 p.Glu2168Lys Uncertain significance Single submitter
- DMBT1 p.Glu2185Gln Uncertain significance Single submitter
- DMBT1 p.Glu2290Lys Uncertain significance Single submitter
- DMBT1 p.Glu57Ala Uncertain significance Single submitter
- DMBT1 p.Glu69Asp Uncertain significance Single submitter
- DMBT1 p.Glu78Asp Uncertain significance Single submitter
- DMBT1 p.Glu78Lys Uncertain significance Single submitter
- DMBT1 p.Glu94Gln Uncertain significance Single submitter
- DMBT1 p.Gly1012Ala Uncertain significance Single submitter
- DMBT1 p.Gly107Arg Uncertain significance Single submitter
- DMBT1 p.Gly1089Ser Uncertain significance Single submitter
- DMBT1 p.Gly1218Ser Uncertain significance Single submitter
- DMBT1 p.Gly121Ala Uncertain significance Single submitter
- DMBT1 p.Gly1644Val Uncertain significance Single submitter
- DMBT1 p.Gly1721Ala Uncertain significance Single submitter
- DMBT1 p.Gly194Val Uncertain significance Single submitter
- DMBT1 p.Gly2215Asp Uncertain significance Single submitter
- DMBT1 p.Gly2506Ser Uncertain significance Single submitter
- DMBT1 p.Gly285Glu Uncertain significance Single submitter
- DMBT1 p.Gly513Asp Uncertain significance Single submitter
- DMBT1 p.Gly608Ser Uncertain significance Single submitter
- DMBT1 p.Gly775Ser Uncertain significance Single submitter
- DMBT1 p.Gly816Asp Uncertain significance Single submitter
- DMBT1 p.Gly986Ala Uncertain significance Single submitter
- DMBT1 p.His1110Arg Uncertain significance Single submitter
- DMBT1 p.His1729Gln Uncertain significance Single submitter
- DMBT1 p.His174Tyr Likely benign Single submitter
- DMBT1 p.His1850Pro Uncertain significance Single submitter
- DMBT1 p.His1945Tyr Uncertain significance Single submitter
- DMBT1 p.His315Tyr Uncertain significance Single submitter
- DMBT1 p.His693Pro Uncertain significance Single submitter
- DMBT1 p.His805Arg Uncertain significance Single submitter
- DMBT1 p.His814Asn Uncertain significance Single submitter
- DMBT1 p.His814Tyr Uncertain significance Single submitter
- DMBT1 p.Ile1091Asn Uncertain significance Single submitter
- DMBT1 p.Ile117Met Uncertain significance Single submitter
- DMBT1 p.Ile1736Val Uncertain significance Single submitter
- DMBT1 p.Ile2193Thr Uncertain significance Single submitter
- DMBT1 p.Ile2295Met Uncertain significance Single submitter
- DMBT1 p.Ile332Val Uncertain significance Single submitter
- DMBT1 p.Ile700Thr Uncertain significance Single submitter
- DMBT1 p.Leu1034Met Uncertain significance Single submitter
- DMBT1 p.Leu187Ile Uncertain significance Single submitter
- DMBT1 p.Leu1965Pro Uncertain significance Single submitter
- DMBT1 p.Leu210Val Uncertain significance Single submitter
- DMBT1 p.Met1685Leu Uncertain significance Single submitter
- DMBT1 p.Met1816Ile Uncertain significance Single submitter
- DMBT1 p.Met2349Ile Uncertain significance Single submitter
- DMBT1 p.Met281Val Likely benign Single submitter
- DMBT1 p.Met541Thr Likely benign Single submitter
- DMBT1 p.Pro1043Ala Uncertain significance Single submitter
- DMBT1 p.Pro1054Arg Uncertain significance Single submitter
- DMBT1 p.Pro1099Gln Uncertain significance Single submitter
- DMBT1 p.Pro1101Arg Uncertain significance Single submitter
- DMBT1 p.Pro1101Leu Uncertain significance Single submitter
- DMBT1 p.Pro1699Ser Uncertain significance Single submitter
- DMBT1 p.Pro1757Gln Uncertain significance Single submitter
All DMBT1 variants
Benign 17
- p.Arg670Cys Multiple submitters ⚠
- p.Asp1796Glu Multiple submitters ⚠
- p.Asp635Asn Multiple submitters ⚠
- p.Asp668Asn Multiple submitters ⚠
- p.Gln1656Arg Multiple submitters
- p.Thr756= Multiple submitters
- c.283+378G>A Single submitter
- c.4891+6C>T Single submitter
- p.Val1761Ile Single submitter ⚠
- c.6026-9G>C No assertion criteria DMBT1-related disorder
- p.Ala268Val No assertion criteria DMBT1-related disorder
- p.Arg1098Gln No assertion criteria DMBT1-related disorder
- p.Arg670Leu No assertion criteria DMBT1-related disorder ⚠
- p.His1084Tyr No assertion criteria DMBT1-related disorder
- p.Pro1909= No assertion criteria DMBT1-related disorder
- p.Ser52Trp No assertion criteria DMBT1-related disorder ⚠
- p.Val1029= No assertion criteria DMBT1-related disorder
Benign/Likely benign 2
- p.Leu1759Ser Multiple submitters
- p.Pro2122Ser Multiple submitters
Likely benign 112
- p.Asp696= Multiple submitters
- p.Ser781= Multiple submitters
- p.Ser842= Multiple submitters
- p.Thr974= Multiple submitters
- c.1420+7C>T Single submitter
- c.1784-844G>A Single submitter
- p.Ala1768= Single submitter
- p.Arg1098= Single submitter
- p.Arg1140Gln Single submitter ⚠
- p.Arg1140Gly Single submitter ⚠
- p.Arg1779Gln Single submitter
- p.Arg2130His Single submitter
- p.Arg2201His Single submitter
- p.Arg2240Gln Single submitter
- p.Arg2292Gln Single submitter
- p.Arg2342Cys Single submitter ⚠
- p.Arg2342His Single submitter ⚠
- p.Arg2401His Single submitter
- p.Arg244Gln Single submitter
- p.Arg2454Lys Single submitter
- p.Arg2510= Single submitter
- p.Arg252Gln Single submitter ⚠
- p.Arg2542Gln Single submitter
- p.Arg339Gln Single submitter ⚠
- p.Arg506= Single submitter
- p.Arg512Gln Single submitter ⚠
- p.Arg614Gln Single submitter ⚠
- p.Arg838Gln Single submitter
- p.Asn1841His Single submitter
- p.Asn286Ser Single submitter ⚠
- p.Asn498= Single submitter
- p.Asn526= Single submitter
- p.Asn529= Single submitter
- p.Asn546Ser Single submitter ⚠
- p.Asn634= Single submitter
- p.Asn637= Single submitter
- p.Asn683His Single submitter
- p.Asp2356Asn Single submitter
- p.Asp520= Single submitter
- p.Asp524= Single submitter
- p.Asp527= Single submitter
- p.Asp635= Single submitter
- p.Asp667= Single submitter
- p.Asp668= Single submitter
- p.Glu2375Lys Single submitter
- p.Gly1775Ser Single submitter
- p.Gly194Ser Single submitter
- p.Gly516= Single submitter
- p.Gly584= Single submitter
- p.Gly584fs Single submitter
- p.Gly662= Single submitter
- p.Gly673= Single submitter
- p.His174Tyr Single submitter ⚠
- p.His585= Single submitter
- p.His585fs Single submitter
- p.His689= Single submitter
- p.Leu510= Single submitter
- p.Leu542Ser Single submitter
- p.Leu68Ser Single submitter
- p.Leu975Trp Single submitter
- p.Lys1851Asn Single submitter
- p.Met281Thr Single submitter
- p.Met281Val Single submitter ⚠
- p.Met541Thr Single submitter ⚠
- p.Phe657= Single submitter
- p.Pro1099= Single submitter
- p.Pro1101= Single submitter
- p.Pro336Ser Single submitter
- p.Ser1067= Single submitter
- p.Ser1847Asn Single submitter ⚠
- p.Ser67Pro Single submitter
- p.Ser680Asn Single submitter ⚠
- p.Ser716Leu Single submitter
- p.Ser983= Single submitter
- p.Thr1635Ser Single submitter
- p.Thr1855Ser Single submitter
- p.Thr1885= Single submitter
- p.Thr1887Ile Single submitter ⚠
- p.Thr2357= Single submitter
- p.Thr649= Single submitter
- p.Thr649Met Single submitter ⚠
- p.Thr719= Single submitter
- p.Thr780Met Single submitter
- p.Tyr2404= Single submitter
- p.Val1674Met Single submitter ⚠
- p.Val297= Single submitter
- c.1033+10C>T No assertion criteria DMBT1-related disorder
- c.1459+7A>T No assertion criteria DMBT1-related disorder
- c.6548+10C>T No assertion criteria DMBT1-related disorder
- p.Arg1626His No assertion criteria DMBT1-related disorder
- p.Arg2060= No assertion criteria DMBT1-related disorder
- p.Arg2208= No assertion criteria DMBT1-related disorder
- p.Arg2401Cys No assertion criteria DMBT1-related disorder ⚠
- p.Arg603= No assertion criteria DMBT1-related disorder
- p.Asn1720= No assertion criteria DMBT1-related disorder
- p.Asp328= No assertion criteria DMBT1-related disorder
- p.Cys1082Ser No assertion criteria EBV-positive nodal T- and NK-cell lymphoma
- p.Gly1696= No assertion criteria DMBT1-related disorder
- p.His1710= No assertion criteria DMBT1-related disorder
- p.His805= No assertion criteria DMBT1-related disorder
- p.Leu715= No assertion criteria DMBT1-related disorder
- p.Pro2154= No assertion criteria DMBT1-related disorder
- p.Pro65Leu No assertion criteria DMBT1-related disorder
- p.Ser1102= No assertion criteria DMBT1-related disorder
- p.Ser968= No assertion criteria DMBT1-related disorder
- p.Thr2087= No assertion criteria DMBT1-related disorder
- p.Thr478= No assertion criteria DMBT1-related disorder
- p.Thr5Lys No assertion criteria DMBT1-related disorder
- p.Thr969= No assertion criteria DMBT1-related disorder
- p.Tyr2412= No assertion criteria DMBT1-related disorder
- p.Val1056= No assertion criteria DMBT1-related disorder
- p.Val746= No assertion criteria DMBT1-related disorder
Uncertain significance 333
Showing the top 300 by review status; the full set is in the sitemap.
- p.Asp696Val Multiple submitters ⚠
- p.His805Asn Multiple submitters ⚠
- p.Ala101Val Single submitter ⚠
- p.Ala1027Asp Single submitter ⚠
- p.Ala1088Thr Single submitter ⚠
- p.Ala1094Val Single submitter ⚠
- p.Ala1630Ser Single submitter ⚠
- p.Ala1687Val Single submitter ⚠
- p.Ala2025Thr Single submitter ⚠
- p.Ala2161Ser Single submitter ⚠
- p.Ala2329Val Single submitter ⚠
- p.Ala483Glu Single submitter ⚠
- p.Ala483Ser Single submitter ⚠
- p.Ala543Pro Single submitter ⚠
- p.Ala543Val Single submitter ⚠
- p.Ala601Val Single submitter ⚠
- p.Ala992Thr Single submitter ⚠
- p.Arg1032Gly Single submitter ⚠
- p.Arg1032Lys Single submitter ⚠
- p.Arg1047Gln Single submitter ⚠
- p.Arg1047Pro Single submitter ⚠
- p.Arg1047Trp Single submitter ⚠
- p.Arg1098Trp Single submitter ⚠
- p.Arg1134Gln Single submitter ⚠
- p.Arg1176Gln Single submitter ⚠
- p.Arg1190Cys Single submitter ⚠
- p.Arg1626Cys Single submitter ⚠
- p.Arg1706Cys Single submitter ⚠
- p.Arg1706His Single submitter ⚠
- p.Arg170His Single submitter ⚠
- p.Arg1823Pro Single submitter ⚠
- p.Arg1837Cys Single submitter ⚠
- p.Arg1837His Single submitter ⚠
- p.Arg1932Cys Single submitter ⚠
- p.Arg1932His Single submitter ⚠
- p.Arg2013Trp Single submitter ⚠
- p.Arg2027Cys Single submitter ⚠
- p.Arg2060His Single submitter ⚠
- p.Arg2095Trp Single submitter ⚠
- p.Arg2107Cys Single submitter ⚠
- p.Arg2130Cys Single submitter ⚠
- p.Arg2201Cys Single submitter ⚠
- p.Arg2201Ser Single submitter ⚠
- p.Arg2208Gln Single submitter ⚠
- p.Arg2227His Single submitter ⚠
- p.Arg2236Ser Single submitter ⚠
- p.Arg2240Trp Single submitter ⚠
- p.Arg2292Trp Single submitter ⚠
- p.Arg242Gly Single submitter ⚠
- p.Arg2449Gln Single submitter ⚠
- p.Arg2449Trp Single submitter ⚠
- p.Arg2467His Single submitter ⚠
- p.Arg246Gln Single submitter ⚠
- p.Arg2472Gln Single submitter ⚠
- p.Arg2481Leu Single submitter ⚠
- p.Arg2502His Single submitter ⚠
- p.Arg2502Leu Single submitter ⚠
- p.Arg2537Gln Single submitter ⚠
- p.Arg302Cys Single submitter ⚠
- p.Arg302His Single submitter ⚠
- p.Arg339Trp Single submitter ⚠
- p.Arg495Lys Single submitter ⚠
- p.Arg502Ser Single submitter ⚠
- p.Arg548Gln Single submitter ⚠
- p.Arg562Cys Single submitter ⚠
- p.Arg562His Single submitter ⚠
- p.Arg610Gly Single submitter ⚠
- p.Arg614Leu Single submitter ⚠
- p.Arg670His Single submitter ⚠
- p.Arg711Ser Single submitter ⚠
- p.Arg787Trp Single submitter ⚠
- p.Arg801Cys Single submitter ⚠
- p.Asn1025Ser Single submitter ⚠
- p.Asn1028His Single submitter ⚠
- p.Asn1045Ile Single submitter ⚠
- p.Asn1081Asp Single submitter ⚠
- p.Asn1642Lys Single submitter ⚠
- p.Asn1673Ser Single submitter ⚠
- p.Asn1726Ser Single submitter ⚠
- p.Asn1773Ser Single submitter ⚠
- p.Asn1801Ser Single submitter ⚠
- p.Asn1939Ser Single submitter ⚠
- p.Asn1961Ser Single submitter ⚠
- p.Asn2249Tyr Single submitter ⚠
- p.Asn2317Ser Single submitter ⚠
- p.Asn266Ser Single submitter ⚠
- p.Asn269Ser Single submitter ⚠
- p.Asn316Ser Single submitter ⚠
- p.Asn634Ser Single submitter ⚠
- p.Asn684Ser Single submitter ⚠
- p.Asn815Asp Single submitter ⚠
- p.Asp1000Glu Single submitter ⚠
- p.Asp1188Val Single submitter ⚠
- p.Asp132His Single submitter ⚠
- p.Asp1620Gly Single submitter ⚠
- p.Asp1645Val Single submitter ⚠
- p.Asp1665Asn Single submitter ⚠
- p.Asp1802Glu Single submitter ⚠
- p.Asp1879Val Single submitter ⚠
- p.Asp1972Glu Single submitter ⚠
- p.Asp2081Tyr Single submitter ⚠
- p.Asp2081Val Single submitter ⚠
- p.Asp2197Asn Single submitter ⚠
- p.Asp264Glu Single submitter ⚠
- p.Asp559Asn Single submitter ⚠
- p.Asp560Asn Single submitter ⚠
- p.Asp973Gly Single submitter ⚠
- p.Cys1036Phe Single submitter ⚠
- p.Cys1676Arg Single submitter ⚠
- p.Cys1727Phe Single submitter ⚠
- p.Cys1921Arg Single submitter ⚠
- p.Cys2291Arg Single submitter ⚠
- p.Gln1033His Single submitter ⚠
- p.Gln1096His Single submitter ⚠
- p.Gln1695Leu Single submitter ⚠
- p.Gln2047Arg Single submitter ⚠
- p.Gln2409Glu Single submitter ⚠
- p.Gln2530Arg Single submitter ⚠
- p.Gln288Pro Single submitter ⚠
- p.Gln743His Single submitter ⚠
- p.Glu1066Lys Single submitter ⚠
- p.Glu1926Gln Single submitter ⚠
- p.Glu2168Lys Single submitter ⚠
- p.Glu2185Gln Single submitter ⚠
- p.Glu2242Gln Single submitter ⚠
- p.Glu2290Lys Single submitter ⚠
- p.Glu327Ala Single submitter ⚠
- p.Glu57Ala Single submitter ⚠
- p.Glu69Asp Single submitter ⚠
- p.Glu747Gln Single submitter ⚠
- p.Glu78Asp Single submitter ⚠
- p.Glu78Lys Single submitter ⚠
- p.Glu94Gln Single submitter ⚠
- p.Gly1012Ala Single submitter ⚠
- p.Gly1015Asp Single submitter ⚠
- p.Gly1051Asp Single submitter ⚠
- p.Gly1064Arg Single submitter ⚠
- p.Gly107Arg Single submitter ⚠
- p.Gly107Val Single submitter ⚠
- p.Gly1089Ser Single submitter ⚠
- p.Gly1218Ser Single submitter ⚠
- p.Gly121Ala Single submitter ⚠
- p.Gly160Asp Single submitter ⚠
- p.Gly1644Val Single submitter ⚠
- p.Gly1660Asp Single submitter ⚠
- p.Gly1660Ser Single submitter ⚠
- p.Gly1709Glu Single submitter ⚠
- p.Gly1721Ala Single submitter ⚠
- p.Gly1780Val Single submitter ⚠
- p.Gly1791Arg Single submitter ⚠
- p.Gly1825Asp Single submitter ⚠
- p.Gly194Arg Single submitter ⚠
- p.Gly194Val Single submitter ⚠
- p.Gly2071Arg Single submitter ⚠
- p.Gly2086Val Single submitter ⚠
- p.Gly2155Arg Single submitter ⚠
- p.Gly2215Asp Single submitter ⚠
- p.Gly2506Ser Single submitter ⚠
- p.Gly256Asp Single submitter ⚠
- p.Gly285Glu Single submitter ⚠
- p.Gly292Asp Single submitter ⚠
- p.Gly292Val Single submitter ⚠
- p.Gly513Asp Single submitter ⚠
- p.Gly590Asp Single submitter ⚠
- p.Gly608Ser Single submitter ⚠
- p.Gly673Glu Single submitter hereditary breast ovarian cancer syndrome ⚠
- p.Gly775Ser Single submitter ⚠
- p.Gly804Val Single submitter ⚠
- p.Gly816Asp Single submitter ⚠
- p.Gly986Ala Single submitter ⚠
- p.Gly99Arg Single submitter ⚠
- p.Gly99Ser Single submitter ⚠
- p.His1065Arg Single submitter ⚠
- p.His1065Asn Single submitter ⚠
- p.His1110Arg Single submitter ⚠
- p.His1729Gln Single submitter ⚠
- p.His1850Pro Single submitter ⚠
- p.His1945Tyr Single submitter ⚠
- p.His2032Arg Single submitter ⚠
- p.His2118Arg Single submitter ⚠
- p.His2344Gln Single submitter ⚠
- p.His2366Gln Single submitter ⚠
- p.His315Tyr Single submitter ⚠
- p.His693Pro Single submitter ⚠
- p.His694Tyr Single submitter ⚠
- p.His805Arg Single submitter ⚠
- p.His814Asn Single submitter ⚠
- p.His814Tyr Single submitter ⚠
- p.Ile1091Asn Single submitter ⚠
- p.Ile117Met Single submitter ⚠
- p.Ile1736Val Single submitter ⚠
- p.Ile2046Val Single submitter ⚠
- p.Ile2167Thr Single submitter ⚠
- p.Ile2193Thr Single submitter ⚠
- p.Ile2282Asn Single submitter ⚠
- p.Ile2295Met Single submitter ⚠
- p.Ile2334Thr Single submitter ⚠
- p.Ile2360Val Single submitter ⚠
- p.Ile332Val Single submitter ⚠
- p.Ile700Thr Single submitter ⚠
- p.Ile795Leu Single submitter ⚠
- p.Leu1034Met Single submitter ⚠
- p.Leu187Ile Single submitter ⚠
- p.Leu1965Pro Single submitter ⚠
- p.Leu210Val Single submitter ⚠
- p.Leu995Pro Single submitter ⚠
- p.Lys2521Asn Single submitter ⚠
- p.Met1685Leu Single submitter ⚠
- p.Met1816Ile Single submitter ⚠
- p.Met2349Ile Single submitter ⚠
- p.Met2349Val Single submitter ⚠
- p.Phe1693Leu Single submitter ⚠
- p.Pro1043Ala Single submitter ⚠
- p.Pro1054Arg Single submitter ⚠
- p.Pro1099Gln Single submitter ⚠
- p.Pro1101Arg Single submitter ⚠
- p.Pro1101Leu Single submitter ⚠
- p.Pro1699Ser Single submitter ⚠
- p.Pro1757Gln Single submitter ⚠
- p.Pro1830Leu Single submitter ⚠
- p.Pro222Ser Single submitter ⚠
- p.Pro224His Single submitter ⚠
- p.Pro2297Ala Single submitter ⚠
- p.Pro2534Thr Single submitter ⚠
- p.Pro2535Gln Single submitter ⚠
- p.Pro2541Ser Single submitter ⚠
- p.Pro340Leu Single submitter ⚠
- p.Pro477Leu Single submitter ⚠
- p.Pro596Ser Single submitter ⚠
- p.Pro813Ala Single submitter ⚠
- p.Pro843Arg Single submitter ⚠
- p.Pro976Arg Single submitter ⚠
- p.Pro976Leu Single submitter ⚠
- p.Ser1041Leu Single submitter ⚠
- p.Ser1041Pro Single submitter ⚠
- p.Ser1079Phe Single submitter ⚠
- p.Ser1079Thr Single submitter ⚠
- p.Ser1085Arg Single submitter ⚠
- p.Ser1085Asn Single submitter ⚠
- p.Ser1095Pro Single submitter ⚠
- p.Ser1116Pro Single submitter ⚠
- p.Ser1724Thr Single submitter ⚠
- p.Ser1738Leu Single submitter ⚠
- p.Ser1789Pro Single submitter ⚠
- p.Ser180Ile Single submitter ⚠
- p.Ser1817Leu Single submitter ⚠
- p.Ser1839Leu Single submitter ⚠
- p.Ser1843Cys Single submitter ⚠
- p.Ser1959Leu Single submitter ⚠
- p.Ser2005Thr Single submitter ⚠
- p.Ser2120Leu Single submitter ⚠
- p.Ser2145Thr Single submitter ⚠
- p.Ser2245Cys Single submitter ⚠
- p.Ser2264Arg Single submitter ⚠
- p.Ser2278Cys Single submitter ⚠
- p.Ser2442Pro Single submitter ⚠
- p.Ser484Leu Single submitter ⚠
- p.Ser484Trp Single submitter ⚠
- p.Ser680Gly Single submitter ⚠
- p.Ser716Thr Single submitter ⚠
- p.Ser723Leu Single submitter ⚠
- p.Ser739Asn Single submitter ⚠
- p.Ser781Leu Single submitter ⚠
- p.Ser792Leu Single submitter ⚠
- p.Ser792Thr Single submitter ⚠
- p.Ser811Arg Single submitter ⚠
- p.Ser842Ile Single submitter ⚠
- p.Ser983Leu Single submitter ⚠
- p.Ser98Pro Single submitter ⚠
- p.Thr1024Ala Single submitter ⚠
- p.Thr133Asn Single submitter ⚠
- p.Thr133Ile Single submitter ⚠
- p.Thr1624Ser Single submitter ⚠
- p.Thr1635Ala Single submitter ⚠
- p.Thr1745Lys Single submitter ⚠
- p.Thr1745Met Single submitter ⚠
- p.Thr1750Ser Single submitter ⚠
- p.Thr1876Ala Single submitter ⚠
- p.Thr1877Met Single submitter ⚠
- p.Thr1905Ile Single submitter ⚠
- p.Thr1978Ile Single submitter ⚠
- p.Thr2038Ile Single submitter ⚠
- p.Thr209Ile Single submitter ⚠
- p.Thr2296Met Single submitter ⚠
- p.Thr2399Ile Single submitter ⚠
- p.Thr2533Asn Single submitter ⚠
- p.Thr257Asn Single submitter ⚠
- p.Thr265Ala Single submitter ⚠
- p.Thr341Ala Single submitter ⚠
- p.Thr709Met Single submitter ⚠
- p.Thr714Arg Single submitter ⚠
- p.Thr714Met Single submitter ⚠
- p.Thr714Ser Single submitter ⚠
- p.Thr719Arg Single submitter ⚠
- p.Thr75Ile Single submitter ⚠
- p.Thr764Ala Single submitter ⚠
- p.Trp2354Cys Single submitter ⚠
- p.Trp279Gly Single submitter ⚠
- p.Trp679Cys Single submitter ⚠
- p.Tyr177Cys Single submitter ⚠