Sugi Variant

Sugi Variant/DNAH10

DNAH10 — 895 ClinVar variants

All ClinVar germline DNAH10 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 441 flagged for review →

3 Pathogenic · 7 Likely pathogenic · 6 Conflicting · 82 Benign · 7 Benign/Likely benign · 107 Likely benign · 683 Uncertain significance

Full DNAH10 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 441

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 4

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 403

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 403

Predictors split 34

The independent predictors disagree with each other — read with care.

All DNAH10 variants

Pathogenic 3

Likely pathogenic 7

Conflicting classifications of pathogenicity 6

Benign 82

Benign/Likely benign 7

Likely benign 107

Uncertain significance 683

Showing the top 300 by review status; the full set is in the sitemap.