Sugi Variant

Sugi Variant/DNAH17

DNAH17 — 1512 ClinVar variants

All ClinVar germline DNAH17 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 674 flagged for review →

7 Pathogenic · 1 Pathogenic/Likely pathogenic · 15 Likely pathogenic · 12 Conflicting · 354 Benign · 168 Likely benign · 955 Uncertain significance

Full DNAH17 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 674

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 9

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 606

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 606

Predictors split 59

The independent predictors disagree with each other — read with care.

All DNAH17 variants

Pathogenic 7

Pathogenic/Likely pathogenic 1

Likely pathogenic 15

Conflicting classifications of pathogenicity 12

Benign 354

Showing the top 300 by review status; the full set is in the sitemap.

Likely benign 168

Uncertain significance 955

Showing the top 300 by review status; the full set is in the sitemap.