DNAJC24 — 14 ClinVar variants
All ClinVar germline DNAJC24 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 14 flagged for review →
14 Uncertain significance
Full DNAJC24 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 14
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 9
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DNAJC24 p.Ala128Val Uncertain significance Single submitter
- DNAJC24 p.Gln43Arg Uncertain significance Single submitter
- DNAJC24 p.Gln6Lys Uncertain significance Single submitter
- DNAJC24 p.Leu80Arg Uncertain significance Single submitter
- DNAJC24 p.Phe59Leu Uncertain significance Single submitter
- DNAJC24 p.Ser44Gly Uncertain significance Single submitter
- DNAJC24 p.Thr51Ala Uncertain significance Single submitter
- DNAJC24 p.Trp66Arg Uncertain significance Single submitter
- DNAJC24 p.Tyr78Cys Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All DNAJC24 variants
Uncertain significance 14
- p.Ala128Val Single submitter ⚠
- p.Arg82Trp Single submitter ⚠
- p.Asp126Gly Single submitter ⚠
- p.Gln43Arg Single submitter ⚠
- p.Gln6Lys Single submitter ⚠
- p.Ile68Ser Single submitter ⚠
- p.Leu80Arg Single submitter ⚠
- p.Phe59Leu Single submitter ⚠
- p.Ser132Arg Single submitter ⚠
- p.Ser44Gly Single submitter ⚠
- p.Thr51Ala Single submitter ⚠
- p.Trp66Arg Single submitter ⚠
- p.Tyr38His Single submitter ⚠
- p.Tyr78Cys Single submitter ⚠