DNAJC9 — 21 ClinVar variants
All ClinVar germline DNAJC9 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 20 flagged for review →
1 Likely benign · 20 Uncertain significance
Full DNAJC9 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 20
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 10
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DNAJC9 p.Arg46Leu Uncertain significance Single submitter
- DNAJC9 p.Asp112Gly Uncertain significance Single submitter
- DNAJC9 p.Glu211Asp Uncertain significance Single submitter
- DNAJC9 p.Gly212Asp Uncertain significance Single submitter
- DNAJC9 p.Ile61Val Uncertain significance Single submitter
- DNAJC9 p.Leu6Arg Uncertain significance Single submitter
- DNAJC9 p.Leu91Phe Uncertain significance Single submitter
- DNAJC9 p.Lys121Arg Uncertain significance Single submitter
- DNAJC9 p.Thr92Ile Uncertain significance Single submitter
- DNAJC9 p.Val68Ala Uncertain significance Single submitter
Predictors split 10
The independent predictors disagree with each other — read with care.
- DNAJC9 p.Arg24Leu Uncertain significance Single submitter
- DNAJC9 p.Gln132Glu Uncertain significance Single submitter
- DNAJC9 p.Gln74Leu Uncertain significance Single submitter
- DNAJC9 p.Glu206Ala Uncertain significance Single submitter
- DNAJC9 p.Glu73Lys Uncertain significance Single submitter
- DNAJC9 p.Gly170Arg Uncertain significance Single submitter
- DNAJC9 p.Gly249Glu Uncertain significance Single submitter
- DNAJC9 p.Ile130Thr Uncertain significance Single submitter
- DNAJC9 p.Met231Thr Uncertain significance Single submitter
- DNAJC9 p.Ser67Phe Uncertain significance Single submitter
All DNAJC9 variants
Likely benign 1
- p.Asn161Ser Single submitter
Uncertain significance 20
- p.Arg24Leu Single submitter ⚠
- p.Arg46Leu Single submitter ⚠
- p.Asp112Gly Single submitter ⚠
- p.Gln132Glu Single submitter ⚠
- p.Gln74Leu Single submitter ⚠
- p.Glu206Ala Single submitter ⚠
- p.Glu211Asp Single submitter ⚠
- p.Glu73Lys Single submitter ⚠
- p.Gly170Arg Single submitter ⚠
- p.Gly212Asp Single submitter ⚠
- p.Gly249Glu Single submitter ⚠
- p.Ile130Thr Single submitter ⚠
- p.Ile61Val Single submitter ⚠
- p.Leu6Arg Single submitter ⚠
- p.Leu91Phe Single submitter ⚠
- p.Lys121Arg Single submitter ⚠
- p.Met231Thr Single submitter ⚠
- p.Ser67Phe Single submitter ⚠
- p.Thr92Ile Single submitter ⚠
- p.Val68Ala Single submitter ⚠