DUSP19 — 46 ClinVar variants
All ClinVar germline DUSP19 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 43 flagged for review →
46 Uncertain significance
Full DUSP19 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 43
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 39
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DUSP19 p.Ala10Val Uncertain significance Single submitter
- DUSP19 p.Arg141Gly Uncertain significance Single submitter
- DUSP19 p.Arg198Cys Uncertain significance Single submitter
- DUSP19 p.Arg198His Uncertain significance Single submitter
- DUSP19 p.Arg211Gly Uncertain significance Single submitter
- DUSP19 p.Asn167Ser Uncertain significance Single submitter
- DUSP19 p.Asp143Gly Uncertain significance Single submitter
- DUSP19 p.Asp37Gly Uncertain significance Single submitter
- DUSP19 p.Asp85Gly Uncertain significance Single submitter
- DUSP19 p.Cys188Phe Uncertain significance Single submitter
- DUSP19 p.Gln58Arg Uncertain significance Single submitter
- DUSP19 p.Glu103Ala Uncertain significance Single submitter
- DUSP19 p.Gly101Glu Uncertain significance Single submitter
- DUSP19 p.Gly51Glu Uncertain significance Single submitter
- DUSP19 p.Gly67Ala Uncertain significance Single submitter
- DUSP19 p.Gly67Arg Uncertain significance Single submitter
- DUSP19 p.His82Asn Uncertain significance Single submitter
- DUSP19 p.Ile136Thr Uncertain significance Single submitter
- DUSP19 p.Ile162Arg Uncertain significance Single submitter
- DUSP19 p.Ile32Met Uncertain significance Single submitter
- DUSP19 p.Leu4Phe Uncertain significance Single submitter
- DUSP19 p.Leu87Gln Uncertain significance Single submitter
- DUSP19 p.Leu87Pro Uncertain significance Single submitter
- DUSP19 p.Leu96Val Uncertain significance Single submitter
- DUSP19 p.Pro121His Uncertain significance Single submitter
- DUSP19 p.Ser178Phe Uncertain significance Single submitter
- DUSP19 p.Ser62Pro Uncertain significance Single submitter
- DUSP19 p.Thr27Ser Uncertain significance Single submitter
- DUSP19 p.Tyr100Phe Uncertain significance Single submitter
- DUSP19 p.Tyr112Ser Uncertain significance Single submitter
- DUSP19 p.Tyr56Cys Uncertain significance Single submitter
- DUSP19 p.Val145Met Uncertain significance Single submitter
- DUSP19 p.Val146Ile Uncertain significance Single submitter
- DUSP19 p.Val146Leu Uncertain significance Single submitter
- DUSP19 p.Val161Ile Uncertain significance Single submitter
- DUSP19 p.Val23Glu Uncertain significance Single submitter
- DUSP19 p.Val23Gly Uncertain significance Single submitter
- DUSP19 p.Val66Ile Uncertain significance Single submitter
- DUSP19 p.Val92Met Uncertain significance Single submitter
Predictors split 4
The independent predictors disagree with each other — read with care.
All DUSP19 variants
Uncertain significance 46
- p.Ala10Val Single submitter ⚠
- p.Arg141Gly Single submitter ⚠
- p.Arg198Cys Single submitter ⚠
- p.Arg198His Single submitter ⚠
- p.Arg211Gly Single submitter ⚠
- p.Asn167Ser Single submitter ⚠
- p.Asp143Gly Single submitter ⚠
- p.Asp37Gly Single submitter ⚠
- p.Asp85Gly Single submitter ⚠
- p.Cys188Phe Single submitter ⚠
- p.Gln196Glu Single submitter
- p.Gln58Arg Single submitter ⚠
- p.Glu103Ala Single submitter ⚠
- p.Glu44Gly Single submitter ⚠
- p.Gly101Glu Single submitter ⚠
- p.Gly51Glu Single submitter ⚠
- p.Gly67Ala Single submitter ⚠
- p.Gly67Arg Single submitter ⚠
- p.His82Asn Single submitter ⚠
- p.Ile136Thr Single submitter ⚠
- p.Ile136Val Single submitter ⚠
- p.Ile162Arg Single submitter ⚠
- p.Ile32Met Single submitter ⚠
- p.Leu4Phe Single submitter ⚠
- p.Leu87Gln Single submitter ⚠
- p.Leu87Pro Single submitter ⚠
- p.Leu96Val Single submitter ⚠
- p.Lys29Asn Single submitter ⚠
- p.Phe110Ile Single submitter
- p.Pro121His Single submitter ⚠
- p.Ser127Pro Single submitter ⚠
- p.Ser178Phe Single submitter ⚠
- p.Ser62Pro Single submitter ⚠
- p.Thr24Ser Single submitter
- p.Thr27Ser Single submitter ⚠
- p.Tyr100Phe Single submitter ⚠
- p.Tyr112Ser Single submitter ⚠
- p.Tyr56Cys Single submitter ⚠
- p.Val145Met Single submitter ⚠
- p.Val146Ile Single submitter ⚠
- p.Val146Leu Single submitter ⚠
- p.Val161Ile Single submitter ⚠
- p.Val23Glu Single submitter ⚠
- p.Val23Gly Single submitter ⚠
- p.Val66Ile Single submitter ⚠
- p.Val92Met Single submitter ⚠