DUSP29 — 57 ClinVar variants
All ClinVar germline DUSP29 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 54 flagged for review →
5 Likely benign · 52 Uncertain significance
Full DUSP29 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 54
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 28
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DUSP29 p.Ala130Thr Uncertain significance Single submitter
- DUSP29 p.Ala135Glu Uncertain significance Single submitter
- DUSP29 p.Ala38Gly Uncertain significance Single submitter
- DUSP29 p.Ala70Val Uncertain significance Single submitter
- DUSP29 p.Arg181Cys Uncertain significance Single submitter
- DUSP29 p.Arg181His Uncertain significance Single submitter
- DUSP29 p.Asn12Ser Uncertain significance Single submitter
- DUSP29 p.Asn56Lys Uncertain significance Single submitter
- DUSP29 p.Asp99Asn Uncertain significance Single submitter
- DUSP29 p.Gln210Arg Uncertain significance Single submitter
- DUSP29 p.Glu67Asp Uncertain significance Single submitter
- DUSP29 p.Glu67Lys Uncertain significance Single submitter
- DUSP29 p.Gly150Val Uncertain significance Single submitter
- DUSP29 p.His54Gln Uncertain significance Single submitter
- DUSP29 p.Ile143Val Uncertain significance Single submitter
- DUSP29 p.Ile64Asn Uncertain significance Single submitter
- DUSP29 p.Lys23Glu Uncertain significance Single submitter
- DUSP29 p.Met168Thr Uncertain significance Single submitter
- DUSP29 p.Met24Thr Uncertain significance Single submitter
- DUSP29 p.Phe124Val Uncertain significance Single submitter
- DUSP29 p.Pro185Leu Uncertain significance Single submitter
- DUSP29 p.Pro98Leu Uncertain significance Single submitter
- DUSP29 p.Ser9Asn Uncertain significance Single submitter
- DUSP29 p.Thr35Ala Uncertain significance Single submitter
- DUSP29 p.Val111Ala Uncertain significance Single submitter
- DUSP29 p.Val177Met Uncertain significance Single submitter
- DUSP29 p.Val183Ile Uncertain significance Single submitter
- DUSP29 p.Val84Met Uncertain significance Single submitter
Predictors split 26
The independent predictors disagree with each other — read with care.
- DUSP29 p.Ala38Asp Uncertain significance Single submitter
- DUSP29 p.Ala70Ser Uncertain significance Single submitter
- DUSP29 p.Arg151Cys Uncertain significance Single submitter
- DUSP29 p.Arg151His Uncertain significance Single submitter
- DUSP29 p.Arg187Trp Uncertain significance Single submitter
- DUSP29 p.Arg194Trp Uncertain significance Single submitter
- DUSP29 p.Arg205Gln Uncertain significance Single submitter
- DUSP29 p.Arg209Cys Likely benign Single submitter
- DUSP29 p.Arg209His Uncertain significance Single submitter
- DUSP29 p.Arg209Pro Uncertain significance Single submitter
- DUSP29 p.Arg43Trp Uncertain significance Single submitter
- DUSP29 p.Asp114Glu Uncertain significance Single submitter
- DUSP29 p.Asp167Val Uncertain significance Single submitter
- DUSP29 p.Gln175His Uncertain significance Single submitter
- DUSP29 p.Leu159Val Uncertain significance Single submitter
- DUSP29 p.Lys166Arg Likely benign Single submitter
- DUSP29 p.Lys166Glu Uncertain significance Single submitter
- DUSP29 p.Lys166Met Uncertain significance Single submitter
- DUSP29 p.Met168Val Uncertain significance Single submitter
- DUSP29 p.Pro127Arg Uncertain significance Single submitter
- DUSP29 p.Ser122Thr Uncertain significance Single submitter
- DUSP29 p.Ser207Phe Uncertain significance Single submitter
- DUSP29 p.Thr118Ile Uncertain significance Single submitter
- DUSP29 p.Thr35Asn Uncertain significance Single submitter
- DUSP29 p.Trp92Arg Uncertain significance Single submitter
- DUSP29 p.Tyr33Cys Uncertain significance Single submitter
All DUSP29 variants
Likely benign 5
- p.Arg206Gln Single submitter
- p.Arg209Cys Single submitter ⚠
- p.Leu116Val Single submitter
- p.Lys166Arg Single submitter ⚠
- p.Ser21Leu Single submitter
Uncertain significance 52
- p.Ala130Thr Single submitter ⚠
- p.Ala135Glu Single submitter ⚠
- p.Ala38Asp Single submitter ⚠
- p.Ala38Gly Single submitter ⚠
- p.Ala70Ser Single submitter ⚠
- p.Ala70Val Single submitter ⚠
- p.Arg151Cys Single submitter ⚠
- p.Arg151His Single submitter ⚠
- p.Arg181Cys Single submitter ⚠
- p.Arg181His Single submitter ⚠
- p.Arg187Trp Single submitter ⚠
- p.Arg194Trp Single submitter ⚠
- p.Arg205Gln Single submitter ⚠
- p.Arg209His Single submitter ⚠
- p.Arg209Pro Single submitter ⚠
- p.Arg43Trp Single submitter ⚠
- p.Asn12Ser Single submitter ⚠
- p.Asn56Lys Single submitter ⚠
- p.Asp114Glu Single submitter ⚠
- p.Asp167Val Single submitter ⚠
- p.Asp99Asn Single submitter ⚠
- p.Gln175His Single submitter ⚠
- p.Gln210Arg Single submitter ⚠
- p.Glu67Asp Single submitter ⚠
- p.Glu67Lys Single submitter ⚠
- p.Gly150Val Single submitter ⚠
- p.His54Gln Single submitter ⚠
- p.Ile143Val Single submitter ⚠
- p.Ile64Asn Single submitter ⚠
- p.Leu159Val Single submitter ⚠
- p.Lys166Glu Single submitter ⚠
- p.Lys166Met Single submitter ⚠
- p.Lys23Glu Single submitter ⚠
- p.Met168Thr Single submitter ⚠
- p.Met168Val Single submitter ⚠
- p.Met24Thr Single submitter ⚠
- p.Phe124Val Single submitter ⚠
- p.Pro127Arg Single submitter ⚠
- p.Pro185Leu Single submitter ⚠
- p.Pro98Leu Single submitter ⚠
- p.Ser122Thr Single submitter ⚠
- p.Ser207Phe Single submitter ⚠
- p.Ser9Asn Single submitter ⚠
- p.Thr118Ile Single submitter ⚠
- p.Thr35Ala Single submitter ⚠
- p.Thr35Asn Single submitter ⚠
- p.Trp92Arg Single submitter ⚠
- p.Tyr33Cys Single submitter ⚠
- p.Val111Ala Single submitter ⚠
- p.Val177Met Single submitter ⚠
- p.Val183Ile Single submitter ⚠
- p.Val84Met Single submitter ⚠