DUSP7 — 37 ClinVar variants
All ClinVar germline DUSP7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 37 flagged for review →
37 Uncertain significance
Full DUSP7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 37
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 22
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- DUSP7 p.Ala125Val Uncertain significance Single submitter
- DUSP7 p.Ala243Asp Uncertain significance Single submitter
- DUSP7 p.Arg11Pro Uncertain significance Single submitter
- DUSP7 p.Arg211Cys Uncertain significance Single submitter
- DUSP7 p.Asn176Ser Uncertain significance Single submitter
- DUSP7 p.Cys391Arg Uncertain significance Single submitter
- DUSP7 p.Gln167Glu Uncertain significance Single submitter
- DUSP7 p.Gln172Glu Uncertain significance Single submitter
- DUSP7 p.Gln399Arg Uncertain significance Single submitter
- DUSP7 p.Glu62Gly Uncertain significance Single submitter
- DUSP7 p.Glu65Ala Uncertain significance Single submitter
- DUSP7 p.Gly234Ser Uncertain significance Single submitter
- DUSP7 p.Gly7Arg Uncertain significance Single submitter
- DUSP7 p.Ile314Val Uncertain significance Single submitter
- DUSP7 p.Met52Ile Uncertain significance Single submitter
- DUSP7 p.Pro53Leu Uncertain significance Single submitter
- DUSP7 p.Pro9Ala Uncertain significance Single submitter
- DUSP7 p.Pro9Ser Uncertain significance Single submitter
- DUSP7 p.Thr180Arg Uncertain significance Single submitter
- DUSP7 p.Thr180Ile Uncertain significance Single submitter
- DUSP7 p.Thr188Ala Uncertain significance Single submitter
- DUSP7 p.Thr419Ala Uncertain significance Single submitter
Predictors split 15
The independent predictors disagree with each other — read with care.
- DUSP7 p.Arg26Gln Uncertain significance Single submitter
- DUSP7 p.Glu146Asp Uncertain significance Single submitter
- DUSP7 p.Gly36Ala Uncertain significance Single submitter
- DUSP7 p.Gly42Ala Uncertain significance Single submitter
- DUSP7 p.Gly50Arg Uncertain significance Single submitter
- DUSP7 p.Ile88Val Uncertain significance Single submitter
- DUSP7 p.Lys121Glu Uncertain significance Single submitter
- DUSP7 p.Phe360Leu Uncertain significance Single submitter
- DUSP7 p.Pro147Leu Uncertain significance Single submitter
- DUSP7 p.Pro9Gln Uncertain significance Single submitter
- DUSP7 p.Ser195Leu Uncertain significance Single submitter
- DUSP7 p.Ser221Leu Uncertain significance Single submitter
- DUSP7 p.Ser396Leu Uncertain significance Single submitter
- DUSP7 p.Thr25Ile Uncertain significance Single submitter
- DUSP7 p.Thr419Met Uncertain significance Single submitter
All DUSP7 variants
Uncertain significance 37
- p.Ala125Val Single submitter ⚠
- p.Ala243Asp Single submitter ⚠
- p.Arg11Pro Single submitter ⚠
- p.Arg211Cys Single submitter ⚠
- p.Arg26Gln Single submitter ⚠
- p.Asn176Ser Single submitter ⚠
- p.Cys391Arg Single submitter ⚠
- p.Gln167Glu Single submitter ⚠
- p.Gln172Glu Single submitter ⚠
- p.Gln399Arg Single submitter ⚠
- p.Glu146Asp Single submitter ⚠
- p.Glu62Gly Single submitter ⚠
- p.Glu65Ala Single submitter ⚠
- p.Gly234Ser Single submitter ⚠
- p.Gly36Ala Single submitter ⚠
- p.Gly42Ala Single submitter ⚠
- p.Gly50Arg Single submitter ⚠
- p.Gly7Arg Single submitter ⚠
- p.Ile314Val Single submitter ⚠
- p.Ile88Val Single submitter ⚠
- p.Lys121Glu Single submitter ⚠
- p.Met52Ile Single submitter ⚠
- p.Phe360Leu Single submitter ⚠
- p.Pro147Leu Single submitter ⚠
- p.Pro53Leu Single submitter ⚠
- p.Pro9Ala Single submitter ⚠
- p.Pro9Gln Single submitter ⚠
- p.Pro9Ser Single submitter ⚠
- p.Ser195Leu Single submitter ⚠
- p.Ser221Leu Single submitter ⚠
- p.Ser396Leu Single submitter ⚠
- p.Thr180Arg Single submitter ⚠
- p.Thr180Ile Single submitter ⚠
- p.Thr188Ala Single submitter ⚠
- p.Thr25Ile Single submitter ⚠
- p.Thr419Ala Single submitter ⚠
- p.Thr419Met Single submitter ⚠