ELOVL6 — 6 ClinVar variants
All ClinVar germline ELOVL6 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 6 flagged for review →
6 Uncertain significance
Full ELOVL6 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 6
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 5
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
Predictors split 1
The independent predictors disagree with each other — read with care.
All ELOVL6 variants
Uncertain significance 6
- p.Asn105Ser Single submitter ⚠
- p.Ile128Val Single submitter ⚠
- p.Ile255Val Single submitter ⚠
- p.Leu237Phe Single submitter ⚠
- p.Val173Met Single submitter ⚠
- p.Val190Ile Single submitter ⚠