EPHB6 — 143 ClinVar variants

All ClinVar germline EPHB6 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

7 Likely benign · 136 Uncertain significance

Full EPHB6 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All EPHB6 variants

Likely benign 7

p.Arg905Gln Multiple submitters
p.Ala663Val Single submitter
p.Arg414His Single submitter
p.Arg720Gln Single submitter
p.Gln687Arg Single submitter
p.Thr630Ile Single submitter
p.Val619Ile Single submitter

Uncertain significance 136

p.Ala341Pro Single submitter
p.Ala341Ser Single submitter
p.Ala341Thr Single submitter
p.Ala453Ser Single submitter
p.Ala567Val Single submitter
p.Ala617Gly Single submitter
p.Ala658Pro Single submitter
p.Ala722Pro Single submitter
p.Ala722Ser Single submitter
p.Ala722Thr Single submitter
p.Arg133His Single submitter
p.Arg151Leu Single submitter
p.Arg208His Single submitter
p.Arg301His Single submitter
p.Arg310Gln Single submitter
p.Arg338Cys Single submitter
p.Arg357Gln Single submitter
p.Arg357Trp Single submitter
p.Arg391His Single submitter
p.Arg427His Single submitter
p.Arg437His Single submitter
p.Arg445Gln Single submitter
p.Arg452Gln Single submitter
p.Arg452Trp Single submitter
p.Arg624Trp Single submitter
p.Arg664Gln Single submitter
p.Arg66Gln Single submitter
p.Arg686His Single submitter
p.Arg686Leu Single submitter
p.Arg693Gln Single submitter
p.Arg693Trp Single submitter
p.Arg695Gln Single submitter
p.Arg734Gln Single submitter
p.Arg734Trp Single submitter
p.Arg743Gln Single submitter
p.Arg764Gln Single submitter
p.Arg778Trp Single submitter
p.Arg795Cys Single submitter
p.Arg795His Single submitter
p.Arg814Cys Single submitter
p.Arg814His Single submitter
p.Arg814Leu Single submitter
p.Arg861Trp Single submitter
p.Arg880Trp Single submitter
p.Arg921Cys Single submitter
p.Arg98His Single submitter
p.Asn969Asp Single submitter
p.Asp401Tyr Single submitter
p.Asp435Asn Single submitter
p.Asp513Tyr Single submitter
p.Asp648Asn Single submitter
p.Asp968Asn Single submitter
p.Cys411Tyr Single submitter
p.Cys428Arg Single submitter
p.Cys965Arg Single submitter
p.Cys965Phe Single submitter
p.Gln529Arg Single submitter
p.Gln772Arg Single submitter
p.Glu162Lys Single submitter
p.Glu33Gln Single submitter
p.Glu412Asp Single submitter
p.Glu469Lys Single submitter
p.Glu542Lys Single submitter
p.Glu653Lys Single submitter
p.Glu675Gly Single submitter
p.Glu860Lys Single submitter
p.Glu876Gln Single submitter
p.Glu987Gln Single submitter
p.Gly186Arg Single submitter
p.Gly252Trp Single submitter
p.Gly276Asp Single submitter
p.Gly289Arg Single submitter
p.Gly298Arg Single submitter
p.Gly321Trp Single submitter
p.Gly383Ser Single submitter
p.Gly413Asp Single submitter
p.Gly422Trp Single submitter
p.Gly568Ser Single submitter
p.Gly642Arg Single submitter
p.Gly708Arg Single submitter
p.Gly930Arg Single submitter
p.His104Arg Single submitter
p.His185Gln Single submitter
p.His340Gln Single submitter
p.His839Arg Single submitter
p.Ile1007Thr Single submitter
p.Leu1009His Single submitter
p.Leu117Val Single submitter
p.Leu149Arg Single submitter
p.Leu322Ile Single submitter
p.Leu392Val Single submitter
p.Leu608Val Single submitter
p.Leu891Phe Single submitter
p.Lys409Arg Single submitter
p.Lys901Glu Single submitter
p.Met16Ile Single submitter
p.Met16Thr Single submitter
p.Phe578Leu Single submitter
p.Pro165Leu Single submitter
p.Pro184Ala Single submitter
p.Pro456Thr Single submitter
p.Pro472Arg Single submitter
p.Pro591Leu Single submitter
p.Pro822Leu Single submitter
p.Pro943Ala Single submitter
p.Pro949Ser Single submitter
p.Pro990Ser Single submitter
p.Ser1019Leu Single submitter
p.Ser140Thr Single submitter
p.Ser170Ala Single submitter
p.Ser201Cys Single submitter
p.Ser490Pro Single submitter
p.Ser499Asn Single submitter
p.Ser552Ile Single submitter
p.Ser742Asn Single submitter
p.Ser796Leu Single submitter
p.Ser823Gly Single submitter
p.Thr246Lys Single submitter
p.Thr246Met Single submitter
p.Thr424Ser Single submitter
p.Thr543Ile Single submitter
p.Thr545Ala Single submitter
p.Thr898Ala Single submitter
p.Thr898Pro Single submitter
p.Tyr457Cys Single submitter
p.Val144Ala Single submitter
p.Val197Leu Single submitter
p.Val236Met Single submitter
p.Val407Met Single submitter
p.Val467Met Single submitter
p.Val488Gly Single submitter
p.Val615Leu Single submitter
p.Val643Met Single submitter
p.Val738Met Single submitter
p.Val793Ile Single submitter
p.Arg66Pro No assertion criteria myoepithelial tumor