FABP6 — 28 ClinVar variants
All ClinVar germline FABP6 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 24 flagged for review →
2 Benign · 26 Uncertain significance
Full FABP6 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 24
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 12
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- FABP6 p.Ala2Val Uncertain significance Single submitter
- FABP6 p.Ala32Val Uncertain significance Single submitter
- FABP6 p.Glu30Lys Uncertain significance Single submitter
- FABP6 p.Gly45Arg Uncertain significance Single submitter
- FABP6 p.Gly76Arg Uncertain significance Single submitter
- FABP6 p.His58Arg Uncertain significance Single submitter
- FABP6 p.Met60Ile Uncertain significance Single submitter
- FABP6 p.Ser26Arg Uncertain significance Single submitter
- FABP6 p.Ser51Thr Uncertain significance Single submitter
- FABP6 p.Thr49Asn Uncertain significance Single submitter
- FABP6 p.Thr59Ile Uncertain significance Single submitter
- FABP6 p.Val28Ile Uncertain significance Single submitter
Predictors split 12
The independent predictors disagree with each other — read with care.
- FABP6 p.Arg126Ile Uncertain significance Single submitter
- FABP6 p.Arg33His Uncertain significance Single submitter
- FABP6 p.Arg33Leu Uncertain significance Single submitter
- FABP6 p.Asp27Asn Uncertain significance Single submitter
- FABP6 p.Glu8Lys Uncertain significance Single submitter
- FABP6 p.Gly56Val Uncertain significance Single submitter
- FABP6 p.Gly57Ala Uncertain significance Single submitter
- FABP6 p.Gly89Arg Uncertain significance Single submitter
- FABP6 p.Ile72Thr Uncertain significance Single submitter
- FABP6 p.Lys6Asn Uncertain significance Single submitter
- FABP6 p.Thr74Ile Uncertain significance Single submitter
- FABP6 p.Val123Leu Uncertain significance Single submitter
All FABP6 variants
Benign 2
- p.Leu21= Single submitter
- p.Leu21His Single submitter
Uncertain significance 26
- p.Ala2Val Single submitter ⚠
- p.Ala32Val Single submitter ⚠
- p.Arg126Ile Single submitter ⚠
- p.Arg33His Single submitter ⚠
- p.Arg33Leu Single submitter ⚠
- p.Asp27Asn Single submitter ⚠
- p.Glu30Lys Single submitter ⚠
- p.Glu8Lys Single submitter ⚠
- p.Gly45Arg Single submitter ⚠
- p.Gly56Val Single submitter ⚠
- p.Gly57Ala Single submitter ⚠
- p.Gly76Arg Single submitter ⚠
- p.Gly89Arg Single submitter ⚠
- p.His58Arg Single submitter ⚠
- p.Ile72Thr Single submitter ⚠
- p.Lys6Asn Single submitter ⚠
- p.Met1Val Single submitter
- p.Met60Ile Single submitter ⚠
- p.Ser26Arg Single submitter ⚠
- p.Ser51Thr Single submitter ⚠
- p.Thr49Asn Single submitter ⚠
- p.Thr59Ile Single submitter ⚠
- p.Thr5Met Single submitter
- p.Thr74Ile Single submitter ⚠
- p.Val123Leu Single submitter ⚠
- p.Val28Ile Single submitter ⚠