FABP7 — 17 ClinVar variants
All ClinVar germline FABP7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 15 flagged for review →
2 Benign · 15 Uncertain significance
Full FABP7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 15
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 7
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- FABP7 p.Leu24Pro Uncertain significance Multiple submitters
- FABP7 p.Glu69Lys Uncertain significance Single submitter
- FABP7 p.Gly25Asp Uncertain significance Single submitter
- FABP7 p.Met21Thr Uncertain significance Single submitter
- FABP7 p.Pro39Arg Uncertain significance Single submitter
- FABP7 p.Ser44Thr Uncertain significance Single submitter
- FABP7 p.Tyr129Asn Uncertain significance Single submitter
Predictors split 8
The independent predictors disagree with each other — read with care.
- FABP7 p.Asn104His Uncertain significance Single submitter
- FABP7 p.Glu69Gly Uncertain significance Single submitter
- FABP7 p.Met114Ile Uncertain significance Single submitter
- FABP7 p.Met116Thr Uncertain significance Single submitter
- FABP7 p.Thr40Met Uncertain significance Single submitter
- FABP7 p.Val106Ile Uncertain significance Single submitter
- FABP7 p.Val51Gly Uncertain significance Single submitter
- FABP7 p.Val85Ile Uncertain significance Single submitter
All FABP7 variants
Benign 2
- c.348+6T>C Single submitter
- p.Gln96= Single submitter
Uncertain significance 15
- p.Leu24Pro Multiple submitters ⚠
- p.Asn104His Single submitter ⚠
- p.Glu69Gly Single submitter ⚠
- p.Glu69Lys Single submitter ⚠
- p.Gly25Asp Single submitter ⚠
- p.Met114Ile Single submitter ⚠
- p.Met116Thr Single submitter ⚠
- p.Met21Thr Single submitter ⚠
- p.Pro39Arg Single submitter ⚠
- p.Ser44Thr Single submitter ⚠
- p.Thr40Met Single submitter ⚠
- p.Tyr129Asn Single submitter ⚠
- p.Val106Ile Single submitter ⚠
- p.Val51Gly Single submitter ⚠
- p.Val85Ile Single submitter ⚠