Sugi Variant

Sugi Variant/FNIP1

FNIP1 — 470 ClinVar variants

All ClinVar germline FNIP1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 179 flagged for review →

21 Pathogenic · 3 Likely pathogenic · 1 Conflicting · 24 Benign · 7 Benign/Likely benign · 222 Likely benign · 192 Uncertain significance

Full FNIP1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 179

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors lean, ClinVar uncertain 142

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

Predictors split 37

The independent predictors disagree with each other — read with care.

All FNIP1 variants

Pathogenic 21

Likely pathogenic 3

Conflicting classifications of pathogenicity 1

Benign 24

Benign/Likely benign 7

Likely benign 222

Uncertain significance 192