FUT7 — 67 ClinVar variants
All ClinVar germline FUT7 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 54 flagged for review →
2 Benign · 8 Likely benign · 57 Uncertain significance
Full FUT7 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 54
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 36
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- FUT7 p.Ala194Thr Uncertain significance Single submitter
- FUT7 p.Ala248Ser Uncertain significance Single submitter
- FUT7 p.Ala26Val Uncertain significance Single submitter
- FUT7 p.Ala42Thr Uncertain significance Single submitter
- FUT7 p.Arg101Gln Uncertain significance Single submitter
- FUT7 p.Arg10Gln Uncertain significance Single submitter
- FUT7 p.Arg10Trp Uncertain significance Single submitter
- FUT7 p.Arg145His Uncertain significance Single submitter
- FUT7 p.Arg155Cys Uncertain significance Single submitter
- FUT7 p.Arg186His Uncertain significance Single submitter
- FUT7 p.Arg223His Uncertain significance Single submitter
- FUT7 p.Arg243Pro Uncertain significance Single submitter
- FUT7 p.Arg294Gln Uncertain significance Single submitter
- FUT7 p.Arg38Trp Uncertain significance Single submitter
- FUT7 p.Arg75Gly Uncertain significance Single submitter
- FUT7 p.Arg82Gln Uncertain significance Single submitter
- FUT7 p.Asn2Ser Uncertain significance Single submitter
- FUT7 p.Asn81Ser Uncertain significance Single submitter
- FUT7 p.Asp276Gly Uncertain significance Single submitter
- FUT7 p.Gln221His Uncertain significance Single submitter
- FUT7 p.Gly16Arg Uncertain significance Single submitter
- FUT7 p.Gly338Ser Uncertain significance Single submitter
- FUT7 p.His326Arg Uncertain significance Single submitter
- FUT7 p.Ile320Leu Uncertain significance Single submitter
- FUT7 p.Leu78Arg Uncertain significance Single submitter
- FUT7 p.Pro41Leu Uncertain significance Single submitter
- FUT7 p.Thr238Met Uncertain significance Single submitter
- FUT7 p.Thr250Ile Uncertain significance Single submitter
- FUT7 p.Trp116Cys Uncertain significance Single submitter
- FUT7 p.Trp31Arg Uncertain significance Single submitter
- FUT7 p.Tyr324Phe Uncertain significance Single submitter
- FUT7 p.Val140Leu Uncertain significance Single submitter
- FUT7 p.Val151Leu Uncertain significance Single submitter
- FUT7 p.Val17Ile Uncertain significance Single submitter
- FUT7 p.Val201Ile Uncertain significance Single submitter
- FUT7 p.Val247Met Uncertain significance Single submitter
Predictors split 18
The independent predictors disagree with each other — read with care.
- FUT7 p.Ala174Thr Uncertain significance Single submitter
- FUT7 p.Ala284Val Uncertain significance Single submitter
- FUT7 p.Arg102Trp Uncertain significance Single submitter
- FUT7 p.Arg110Trp Uncertain significance Single submitter
- FUT7 p.Arg144Gln Uncertain significance Single submitter
- FUT7 p.Arg198Trp Uncertain significance Single submitter
- FUT7 p.Arg204Cys Uncertain significance Single submitter
- FUT7 p.Arg208Trp Uncertain significance Single submitter
- FUT7 p.Arg302His Uncertain significance Single submitter
- FUT7 p.Arg314Trp Uncertain significance Single submitter
- FUT7 p.Asn244Asp Uncertain significance Single submitter
- FUT7 p.Asp312Asn Uncertain significance Single submitter
- FUT7 p.Asp66Val Uncertain significance Single submitter
- FUT7 p.Gly249Ser Benign Single submitter
- FUT7 p.Leu283Val Uncertain significance Single submitter
- FUT7 p.Phe298Cys Uncertain significance Single submitter
- FUT7 p.Pro111Leu Uncertain significance Single submitter
- FUT7 p.Pro165Leu Uncertain significance Single submitter
All FUT7 variants
Benign 2
- p.Tyr324His Multiple submitters
- p.Gly249Ser Single submitter ⚠
Likely benign 8
- p.Ala194Val Single submitter
- p.Ala212Thr Single submitter
- p.Arg281Gln Single submitter
- p.Arg75His Single submitter
- p.Asp66Asn Single submitter
- p.Ser163Leu Single submitter
- p.Tyr71= Single submitter
- p.Val21Ala Single submitter
Uncertain significance 57
- p.Ala174Thr Single submitter ⚠
- p.Ala194Thr Single submitter ⚠
- p.Ala248Ser Single submitter ⚠
- p.Ala26Val Single submitter ⚠
- p.Ala284Val Single submitter ⚠
- p.Ala42Thr Single submitter ⚠
- p.Arg101Gln Single submitter ⚠
- p.Arg102Trp Single submitter ⚠
- p.Arg10Gln Single submitter ⚠
- p.Arg10Trp Single submitter ⚠
- p.Arg110Trp Single submitter ⚠
- p.Arg144Gln Single submitter ⚠
- p.Arg145His Single submitter ⚠
- p.Arg155Cys Single submitter ⚠
- p.Arg186His Single submitter ⚠
- p.Arg198Trp Single submitter ⚠
- p.Arg204Cys Single submitter ⚠
- p.Arg208Trp Single submitter ⚠
- p.Arg223His Single submitter ⚠
- p.Arg243Pro Single submitter ⚠
- p.Arg294Gln Single submitter ⚠
- p.Arg302His Single submitter ⚠
- p.Arg314Trp Single submitter ⚠
- p.Arg38Trp Single submitter ⚠
- p.Arg75Gly Single submitter ⚠
- p.Arg82Gln Single submitter ⚠
- p.Asn244Asp Single submitter ⚠
- p.Asn2Ser Single submitter ⚠
- p.Asn81Ser Single submitter ⚠
- p.Asp146Asn Single submitter
- p.Asp276Gly Single submitter ⚠
- p.Asp312Asn Single submitter ⚠
- p.Asp66Val Single submitter ⚠
- p.Gln221His Single submitter ⚠
- p.Gly16Arg Single submitter ⚠
- p.Gly338Ser Single submitter ⚠
- p.His326Arg Single submitter ⚠
- p.Ile320Leu Single submitter ⚠
- p.Leu283Val Single submitter ⚠
- p.Leu78Arg Single submitter ⚠
- p.Phe298Cys Single submitter ⚠
- p.Pro111Leu Single submitter ⚠
- p.Pro165Leu Single submitter ⚠
- p.Pro41Leu Single submitter ⚠
- p.Thr238Met Single submitter ⚠
- p.Thr250Ile Single submitter ⚠
- p.Trp116Cys Single submitter ⚠
- p.Trp31Arg Single submitter ⚠
- p.Tyr324Phe Single submitter ⚠
- p.Val140Leu Single submitter ⚠
- p.Val151Leu Single submitter ⚠
- p.Val17Ile Single submitter ⚠
- p.Val199Met Single submitter
- p.Val201Ile Single submitter ⚠
- p.Val247Met Single submitter ⚠
- p.Val307Met Single submitter
- p.Val91Met Single submitter