GALNT6 — 114 ClinVar variants
All ClinVar germline GALNT6 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 100 flagged for review →
4 Benign · 3 Likely benign · 107 Uncertain significance
Full GALNT6 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 100
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 81
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- GALNT6 p.Ala115Thr Uncertain significance Single submitter
- GALNT6 p.Ala144Thr Uncertain significance Single submitter
- GALNT6 p.Ala144Val Uncertain significance Single submitter
- GALNT6 p.Ala284Asp Uncertain significance Single submitter
- GALNT6 p.Ala432Thr Uncertain significance Single submitter
- GALNT6 p.Arg12His Uncertain significance Single submitter
- GALNT6 p.Arg149Gln Uncertain significance Single submitter
- GALNT6 p.Arg171Gln Uncertain significance Single submitter
- GALNT6 p.Arg171Trp Uncertain significance Single submitter
- GALNT6 p.Arg172Cys Uncertain significance Single submitter
- GALNT6 p.Arg246Trp Uncertain significance Single submitter
- GALNT6 p.Arg253Trp Uncertain significance Single submitter
- GALNT6 p.Arg389Gln Uncertain significance Single submitter
- GALNT6 p.Arg410Trp Uncertain significance Single submitter
- GALNT6 p.Arg426His Uncertain significance Single submitter
- GALNT6 p.Arg49Trp Uncertain significance Single submitter
- GALNT6 p.Arg517Cys Uncertain significance Single submitter
- GALNT6 p.Arg545Cys Uncertain significance Single submitter
- GALNT6 p.Asn111Ser Uncertain significance Single submitter
- GALNT6 p.Asn187Lys Uncertain significance Single submitter
- GALNT6 p.Asn427Lys Uncertain significance Single submitter
- GALNT6 p.Asn476Asp Uncertain significance Single submitter
- GALNT6 p.Asn547Ser Uncertain significance Single submitter
- GALNT6 p.Asn62Asp Uncertain significance Single submitter
- GALNT6 p.Asp148Asn Uncertain significance Single submitter
- GALNT6 p.Asp344Asn Uncertain significance Single submitter
- GALNT6 p.Asp543Glu Uncertain significance Single submitter
- GALNT6 p.Asp586Glu Uncertain significance Single submitter
- GALNT6 p.Cys509Phe Uncertain significance Single submitter
- GALNT6 p.Gln617Pro Uncertain significance Single submitter
- GALNT6 p.Gln80Arg Uncertain significance Single submitter
- GALNT6 p.Glu104Lys Uncertain significance Single submitter
- GALNT6 p.Glu188Lys Uncertain significance Single submitter
- GALNT6 p.Glu288Asp Uncertain significance Single submitter
- GALNT6 p.Glu35Lys Uncertain significance Single submitter
- GALNT6 p.Glu36Lys Uncertain significance Single submitter
- GALNT6 p.Glu456Lys Uncertain significance Single submitter
- GALNT6 p.Glu579Lys Uncertain significance Single submitter
- GALNT6 p.Gly321Ser Uncertain significance Single submitter
- GALNT6 p.Gly529Ser Uncertain significance Single submitter
- GALNT6 p.Gly562Asp Uncertain significance Single submitter
- GALNT6 p.His473Gln Uncertain significance Single submitter
- GALNT6 p.His616Gln Uncertain significance Single submitter
- GALNT6 p.Ile182Asn Uncertain significance Single submitter
- GALNT6 p.Ile183Thr Uncertain significance Single submitter
- GALNT6 p.Ile207Leu Uncertain significance Single submitter
- GALNT6 p.Ile250Leu Uncertain significance Single submitter
- GALNT6 p.Leu431Pro Uncertain significance Single submitter
- GALNT6 p.Leu46Pro Uncertain significance Single submitter
- GALNT6 p.Leu481Pro Uncertain significance Single submitter
- GALNT6 p.Lys138Thr Uncertain significance Single submitter
- GALNT6 p.Lys139Arg Uncertain significance Single submitter
- GALNT6 p.Lys44Arg Uncertain significance Single submitter
- GALNT6 p.Lys50Arg Uncertain significance Single submitter
- GALNT6 p.Met68Ile Uncertain significance Single submitter
- GALNT6 p.Met68Val Uncertain significance Single submitter
- GALNT6 p.Met9Ile Uncertain significance Single submitter
- GALNT6 p.Phe306Ser Uncertain significance Single submitter
- GALNT6 p.Pro107Ala Uncertain significance Single submitter
- GALNT6 p.Pro175Ala Uncertain significance Single submitter
- GALNT6 p.Pro175Arg Uncertain significance Single submitter
- GALNT6 p.Pro175Leu Uncertain significance Single submitter
- GALNT6 p.Pro296Thr Uncertain significance Single submitter
- GALNT6 p.Pro336Leu Uncertain significance Single submitter
- GALNT6 p.Pro414His Uncertain significance Single submitter
- GALNT6 p.Pro91Ser Uncertain significance Single submitter
- GALNT6 p.Ser258Thr Uncertain significance Single submitter
- GALNT6 p.Ser33Arg Uncertain significance Single submitter
- GALNT6 p.Ser422Arg Uncertain significance Single submitter
- GALNT6 p.Ser458Ala Uncertain significance Single submitter
- GALNT6 p.Ser565Asn Uncertain significance Single submitter
- GALNT6 p.Thr494Ala Uncertain significance Single submitter
- GALNT6 p.Trp42Ser Uncertain significance Single submitter
- GALNT6 p.Tyr137His Uncertain significance Single submitter
- GALNT6 p.Tyr480Cys Uncertain significance Single submitter
- GALNT6 p.Tyr498Cys Uncertain significance Single submitter
- GALNT6 p.Val200Ile Uncertain significance Single submitter
- GALNT6 p.Val232Met Uncertain significance Single submitter
- GALNT6 p.Val299Ile Uncertain significance Single submitter
- GALNT6 p.Val299Leu Uncertain significance Single submitter
- GALNT6 p.Val53Ala Uncertain significance Single submitter
Predictors split 19
The independent predictors disagree with each other — read with care.
- GALNT6 p.Ala19Asp Uncertain significance Single submitter
- GALNT6 p.Arg242Gln Uncertain significance Single submitter
- GALNT6 p.Arg246Gln Uncertain significance Single submitter
- GALNT6 p.Arg285Gln Uncertain significance Single submitter
- GALNT6 p.Arg341Thr Uncertain significance Single submitter
- GALNT6 p.Asn447Lys Uncertain significance Single submitter
- GALNT6 p.Asp289His Uncertain significance Single submitter
- GALNT6 p.Glu288Lys Uncertain significance Single submitter
- GALNT6 p.Gly277Ser Uncertain significance Single submitter
- GALNT6 p.Gly532Ser Uncertain significance Single submitter
- GALNT6 p.Ile301Phe Uncertain significance Single submitter
- GALNT6 p.Leu156Pro Uncertain significance Single submitter
- GALNT6 p.Leu22Pro Uncertain significance Single submitter
- GALNT6 p.Phe323Leu Uncertain significance Single submitter
- GALNT6 p.Ser463Leu Uncertain significance Single submitter
- GALNT6 p.Ser84Cys Uncertain significance Single submitter
- GALNT6 p.Thr204Ile Uncertain significance Single submitter
- GALNT6 p.Val241Ala Uncertain significance Single submitter
- GALNT6 p.Val241Met Uncertain significance Single submitter
All GALNT6 variants
Benign 4
- p.Lys138Asn Multiple submitters
- p.Val181= Multiple submitters
- p.Val423Ile Multiple submitters
- c.1755+7C>T Single submitter
Likely benign 3
- p.Arg49Gln Single submitter
- p.Phe568= Single submitter
- p.Val622Ile Single submitter
Uncertain significance 107
- p.Ala115Thr Single submitter ⚠
- p.Ala144Thr Single submitter ⚠
- p.Ala144Val Single submitter ⚠
- p.Ala19Asp Single submitter ⚠
- p.Ala284Asp Single submitter ⚠
- p.Ala432Thr Single submitter ⚠
- p.Ala60Asp Single submitter
- p.Arg12His Single submitter ⚠
- p.Arg149Gln Single submitter ⚠
- p.Arg171Gln Single submitter ⚠
- p.Arg171Trp Single submitter ⚠
- p.Arg172Cys Single submitter ⚠
- p.Arg242Gln Single submitter ⚠
- p.Arg246Gln Single submitter ⚠
- p.Arg246Trp Single submitter ⚠
- p.Arg253Trp Single submitter ⚠
- p.Arg285Gln Single submitter ⚠
- p.Arg320Gln Single submitter
- p.Arg341Thr Single submitter ⚠
- p.Arg342His Single submitter
- p.Arg389Gln Single submitter ⚠
- p.Arg410Trp Single submitter ⚠
- p.Arg426His Single submitter ⚠
- p.Arg49Trp Single submitter ⚠
- p.Arg517Cys Single submitter ⚠
- p.Arg545Cys Single submitter ⚠
- p.Asn111Ser Single submitter ⚠
- p.Asn187Lys Single submitter ⚠
- p.Asn427Lys Single submitter ⚠
- p.Asn447Lys Single submitter ⚠
- p.Asn476Asp Single submitter ⚠
- p.Asn547Ser Single submitter ⚠
- p.Asn62Asp Single submitter ⚠
- p.Asp148Asn Single submitter ⚠
- p.Asp289His Single submitter ⚠
- p.Asp344Asn Single submitter ⚠
- p.Asp543Glu Single submitter ⚠
- p.Asp586Glu Single submitter ⚠
- p.Cys509Phe Single submitter ⚠
- p.Gln617Pro Single submitter ⚠
- p.Gln80Arg Single submitter ⚠
- p.Glu104Lys Single submitter ⚠
- p.Glu188Lys Single submitter ⚠
- p.Glu288Asp Single submitter ⚠
- p.Glu288Lys Single submitter ⚠
- p.Glu35Lys Single submitter ⚠
- p.Glu36Lys Single submitter ⚠
- p.Glu456Lys Single submitter ⚠
- p.Glu579Lys Single submitter ⚠
- p.Gly277Ser Single submitter ⚠
- p.Gly321Ser Single submitter ⚠
- p.Gly460Ser Single submitter
- p.Gly529Ser Single submitter ⚠
- p.Gly532Ser Single submitter ⚠
- p.Gly562Asp Single submitter ⚠
- p.His473Gln Single submitter ⚠
- p.His616Gln Single submitter ⚠
- p.Ile182Asn Single submitter ⚠
- p.Ile183Leu Single submitter
- p.Ile183Thr Single submitter ⚠
- p.Ile207Leu Single submitter ⚠
- p.Ile250Leu Single submitter ⚠
- p.Ile301Phe Single submitter ⚠
- p.Leu156Pro Single submitter ⚠
- p.Leu22Pro Single submitter ⚠
- p.Leu431Pro Single submitter ⚠
- p.Leu46Pro Single submitter ⚠
- p.Leu481Pro Single submitter ⚠
- p.Lys138Thr Single submitter ⚠
- p.Lys139Arg Single submitter ⚠
- p.Lys44Arg Single submitter ⚠
- p.Lys50Arg Single submitter ⚠
- p.Met68Ile Single submitter ⚠
- p.Met68Val Single submitter ⚠
- p.Met9Ile Single submitter ⚠
- p.Phe306Ser Single submitter ⚠
- p.Phe323Leu Single submitter ⚠
- p.Pro107Ala Single submitter ⚠
- p.Pro175Ala Single submitter ⚠
- p.Pro175Arg Single submitter ⚠
- p.Pro175Leu Single submitter ⚠
- p.Pro296Thr Single submitter ⚠
- p.Pro336Leu Single submitter ⚠
- p.Pro414His Single submitter ⚠
- p.Pro91Ser Single submitter ⚠
- p.Ser258Thr Single submitter ⚠
- p.Ser33Arg Single submitter ⚠
- p.Ser351Cys Single submitter
- p.Ser422Arg Single submitter ⚠
- p.Ser458Ala Single submitter ⚠
- p.Ser463Leu Single submitter ⚠
- p.Ser565Asn Single submitter ⚠
- p.Ser84Cys Single submitter ⚠
- p.Thr204Ile Single submitter ⚠
- p.Thr494Ala Single submitter ⚠
- p.Trp42Ser Single submitter ⚠
- p.Tyr137His Single submitter ⚠
- p.Tyr480Cys Single submitter ⚠
- p.Tyr498Cys Single submitter ⚠
- p.Val200Ile Single submitter ⚠
- p.Val232Met Single submitter ⚠
- p.Val241Ala Single submitter ⚠
- p.Val241Met Single submitter ⚠
- p.Val299Ile Single submitter ⚠
- p.Val299Leu Single submitter ⚠
- p.Val429Ala Single submitter
- p.Val53Ala Single submitter ⚠