IL23R — 439 ClinVar variants
All ClinVar germline IL23R variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 217 flagged for review →
9 Conflicting · 15 Benign · 10 Benign/Likely benign · 157 Likely benign · 248 Uncertain significance
Full IL23R gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 217
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 9
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
- IL23R p.Asn471Ser Conflicting Single submitter
- IL23R p.Glu168Gly Conflicting Single submitter
- IL23R p.Glu593Lys Conflicting Single submitter
- IL23R p.Met99Val Conflicting Single submitter
-
IL23R p.Pro464Leu
Conflicting
Single submitter
IL23R-related disorder
- IL23R p.Ser416Asn Conflicting Single submitter
- IL23R p.Tyr241His Conflicting Single submitter
- IL23R p.Val291Ile Conflicting Single submitter
- IL23R p.Val601Met Conflicting Single submitter
Predictors lean, ClinVar uncertain 191
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 191
- IL23R p.Ala531Thr Uncertain significance Multiple submitters
- IL23R p.Cys115Gly Uncertain significance Multiple submitters
- IL23R p.Cys558Arg Uncertain significance Multiple submitters
- IL23R p.Gln465Pro Uncertain significance Multiple submitters
- IL23R p.Gln564Lys Uncertain significance Multiple submitters
- IL23R p.Glu169Lys Uncertain significance Multiple submitters
- IL23R p.Glu205Val Uncertain significance Multiple submitters
- IL23R p.Glu269Gln Uncertain significance Multiple submitters
- IL23R p.Ile563Met Uncertain significance Multiple submitters
- IL23R p.Leu428Pro Uncertain significance Multiple submitters
- IL23R p.Lys250Asn Uncertain significance Multiple submitters
- IL23R p.Lys63Glu Uncertain significance Multiple submitters
- IL23R p.Pro124Leu Uncertain significance Multiple submitters
- IL23R p.Ser19Gly Uncertain significance Multiple submitters
- IL23R p.Ser467Leu Uncertain significance Multiple submitters
- IL23R p.Ser625Pro Uncertain significance Multiple submitters
- IL23R p.Thr132Ile Uncertain significance Multiple submitters
- IL23R p.Thr318Ile Uncertain significance Multiple submitters
- IL23R p.Thr588Asn Uncertain significance Multiple submitters
- IL23R p.Trp242Cys Uncertain significance Multiple submitters
- IL23R p.Tyr476Asp Uncertain significance Multiple submitters
- IL23R p.Val277Met Uncertain significance Multiple submitters
- IL23R p.Ala10Thr Uncertain significance Single submitter
- IL23R p.Ala13Thr Uncertain significance Single submitter
- IL23R p.Ala148Gly Uncertain significance Single submitter
- IL23R p.Ala201Thr Uncertain significance Single submitter
- IL23R p.Ala223Gly Uncertain significance Single submitter
- IL23R p.Ala531Val Uncertain significance Single submitter
- IL23R p.Ala54Val Uncertain significance Single submitter
- IL23R p.Ala55Thr Uncertain significance Single submitter
- IL23R p.Arg378Lys Uncertain significance Single submitter
- IL23R p.Arg461Lys Uncertain significance Single submitter
- IL23R p.Arg461Thr Uncertain significance Single submitter
- IL23R p.Asn180Ser Uncertain significance Single submitter
- IL23R p.Asn420Ser Uncertain significance Single submitter
- IL23R p.Asn421His Uncertain significance Single submitter
- IL23R p.Asn500Asp Uncertain significance Single submitter
- IL23R p.Asn502Ser Uncertain significance Single submitter
- IL23R p.Asn542Thr Uncertain significance Single submitter
- IL23R p.Asn615Ser Uncertain significance Single submitter
- IL23R p.Asn91Ser Uncertain significance Single submitter
- IL23R p.Asn91Thr Uncertain significance Single submitter
- IL23R p.Asp118Asn Uncertain significance Single submitter
- IL23R p.Asp129Glu Uncertain significance Single submitter
- IL23R p.Asp243Asn Uncertain significance Single submitter
- IL23R p.Asp330Glu Uncertain significance Single submitter
- IL23R p.Asp462His Uncertain significance Single submitter
- IL23R p.Asp470Asn Uncertain significance Single submitter
- IL23R p.Asp479Glu Uncertain significance Single submitter
- IL23R p.Asp479His Uncertain significance Single submitter
- IL23R p.Asp9Glu Uncertain significance Single submitter
- IL23R p.Cys59Arg Uncertain significance Single submitter
- IL23R p.Gln171His Uncertain significance Single submitter
- IL23R p.Gln245Glu Uncertain significance Single submitter
- IL23R p.Gln263Lys Uncertain significance Single submitter
- IL23R p.Gln279Glu Uncertain significance Single submitter
- IL23R p.Gln3Arg Uncertain significance Single submitter
- IL23R p.Gln525Lys Uncertain significance Single submitter
- IL23R p.Gln53His Uncertain significance Single submitter
- IL23R p.Gln587Glu Uncertain significance Single submitter
- IL23R p.Gln614Pro Uncertain significance Single submitter
- IL23R p.Glu104Gln Uncertain significance Single submitter
- IL23R p.Glu206Lys Uncertain significance Single submitter
- IL23R p.Glu269Asp Uncertain significance Single submitter
- IL23R p.Glu436Ala Uncertain significance Single submitter
- IL23R p.Glu459Gln Uncertain significance Single submitter
- IL23R p.Glu548Gln Uncertain significance Single submitter
- IL23R p.Glu568Lys Uncertain significance Single submitter
- IL23R p.Glu582Val Uncertain significance Single submitter
- IL23R p.Glu604Asp Uncertain significance Single submitter
- IL23R p.Gly189Ser Uncertain significance Single submitter
- IL23R p.Gly300Asp Uncertain significance Single submitter
- IL23R p.Gly519Arg Uncertain significance Single submitter
- IL23R p.His108Arg Uncertain significance Single submitter
- IL23R p.His108Gln Uncertain significance Single submitter
- IL23R p.His108Tyr Uncertain significance Single submitter
- IL23R p.His161Arg Uncertain significance Single submitter
- IL23R p.His329Asn Uncertain significance Single submitter
- IL23R p.His329Gln Uncertain significance Single submitter
- IL23R p.His33Arg Uncertain significance Single submitter
- IL23R p.His345Tyr Uncertain significance Single submitter
- IL23R p.Ile16Val Uncertain significance Single submitter
- IL23R p.Ile179Thr Uncertain significance Single submitter
- IL23R p.Ile219Val Uncertain significance Single submitter
- IL23R p.Ile225Val Uncertain significance Single submitter
- IL23R p.Ile231Val Uncertain significance Single submitter
- IL23R p.Ile239Leu Uncertain significance Single submitter
- IL23R p.Ile248Ser Uncertain significance Single submitter
- IL23R p.Ile248Thr Uncertain significance Single submitter
- IL23R p.Ile248Val Uncertain significance Single submitter
- IL23R p.Ile341Val Uncertain significance Single submitter
- IL23R p.Ile34Leu Uncertain significance Single submitter
- IL23R p.Ile354Phe Uncertain significance Single submitter
- IL23R p.Ile354Thr Uncertain significance Single submitter
- IL23R p.Ile361Thr Uncertain significance Single submitter
- IL23R p.Ile369Val Uncertain significance Single submitter
- IL23R p.Ile373Phe Uncertain significance Single submitter
- IL23R p.Ile373Thr Uncertain significance Single submitter
- IL23R p.Ile434Thr Uncertain significance Single submitter
- IL23R p.Ile434Val Uncertain significance Single submitter
- IL23R p.Ile440Val Uncertain significance Single submitter
- IL23R p.Ile50Val Uncertain significance Single submitter
- IL23R p.Ile544Val Uncertain significance Single submitter
- IL23R p.Ile56Phe Uncertain significance Single submitter
- IL23R p.Ile56Val Uncertain significance Single submitter
- IL23R p.Ile608Thr Uncertain significance Single submitter
- IL23R p.Ile6Ser Uncertain significance Single submitter
- IL23R p.Ile71Val Uncertain significance Single submitter
- IL23R p.Leu151Phe Uncertain significance Single submitter
- IL23R p.Leu165Phe Uncertain significance Single submitter
- IL23R p.Leu193Phe Uncertain significance Single submitter
- IL23R p.Leu193Ser Uncertain significance Single submitter
- IL23R p.Leu367Phe Uncertain significance Single submitter
- IL23R p.Leu372Phe Uncertain significance Single submitter
- IL23R p.Leu389Ser Uncertain significance Single submitter
- IL23R p.Leu390Trp Uncertain significance Single submitter
- IL23R p.Leu396Phe Uncertain significance Single submitter
- IL23R p.Leu492Met Uncertain significance Single submitter
- IL23R p.Leu524Ile Uncertain significance Single submitter
- IL23R p.Leu87Phe Uncertain significance Single submitter
- IL23R p.Lys107Ile Uncertain significance Single submitter
- IL23R p.Lys150Thr Uncertain significance Single submitter
- IL23R p.Lys157Glu Uncertain significance Single submitter
- IL23R p.Lys289Glu Uncertain significance Single submitter
- IL23R p.Lys314Glu Uncertain significance Single submitter
- IL23R p.Lys385Gln Uncertain significance Single submitter
- IL23R p.Lys385Thr Uncertain significance Single submitter
- IL23R p.Lys452Thr Uncertain significance Single submitter
- IL23R p.Lys526Asn Uncertain significance Single submitter
- IL23R p.Lys629Glu Uncertain significance Single submitter
- IL23R p.Lys63Arg Uncertain significance Single submitter
- IL23R p.Lys82Asn Uncertain significance Single submitter
- IL23R p.Met204Leu Uncertain significance Single submitter
- IL23R p.Met204Val Uncertain significance Single submitter
- IL23R p.Met360Ile Uncertain significance Single submitter
- IL23R p.Met411Ile Uncertain significance Single submitter
- IL23R p.Met433Leu Uncertain significance Single submitter
- IL23R p.Phe594Ile Uncertain significance Single submitter
- IL23R p.Pro306Ala Uncertain significance Single submitter
- IL23R p.Pro306Ser Uncertain significance Single submitter
- IL23R p.Pro320Ser Uncertain significance Single submitter
- IL23R p.Pro38Thr Uncertain significance Single submitter
- IL23R p.Pro443Thr Uncertain significance Single submitter
- IL23R p.Pro512Ser Uncertain significance Single submitter
- IL23R p.Pro585Ser Uncertain significance Single submitter
- IL23R p.Pro95Ser Uncertain significance Single submitter
- IL23R p.Ser120Thr Uncertain significance Single submitter
- IL23R p.Ser19Asn Uncertain significance Single submitter
- IL23R p.Ser221Phe Uncertain significance Single submitter
- IL23R p.Ser308Arg Uncertain significance Single submitter
Predictors split 17
The independent predictors disagree with each other — read with care.
- IL23R p.Val160Ala Uncertain significance Multiple submitters
- IL23R p.Arg86Trp Uncertain significance Single submitter
- IL23R p.Asp118His Uncertain significance Single submitter
- IL23R p.Cys296Tyr Uncertain significance Single submitter
- IL23R p.Gln487His Uncertain significance Single submitter
- IL23R p.Ile28Thr Uncertain significance Single submitter
- IL23R p.Ile41Asn Uncertain significance Single submitter
- IL23R p.Leu113Pro Uncertain significance Single submitter
- IL23R p.Lys485Asn Uncertain significance Single submitter
- IL23R p.Met44Thr Uncertain significance Single submitter
- IL23R p.Phe292Leu Uncertain significance Single submitter
- IL23R p.Thr275Pro Uncertain significance Single submitter
- IL23R p.Trp20Arg Uncertain significance Single submitter
- IL23R p.Trp395Arg Uncertain significance Single submitter
- IL23R p.Tyr173Cys Uncertain significance Single submitter
- IL23R p.Tyr257Cys Uncertain significance Single submitter
- IL23R p.Tyr51His Uncertain significance Single submitter
All IL23R variants
Conflicting classifications of pathogenicity 9
- p.Asn471Ser Single submitter ⚠
- p.Glu168Gly Single submitter ⚠
- p.Glu593Lys Single submitter ⚠
- p.Met99Val Single submitter ⚠
- p.Pro464Leu Single submitter IL23R-related disorder ⚠
- p.Ser416Asn Single submitter ⚠
- p.Tyr241His Single submitter ⚠
- p.Val291Ile Single submitter ⚠
- p.Val601Met Single submitter ⚠
Benign 15
- p.Arg381Gln Multiple submitters
- p.Gln3His Multiple submitters
- p.Gly149Arg Multiple submitters
- p.Leu310Pro Multiple submitters
- p.Val362Ile Multiple submitters
- c.1148+20C>T Single submitter
- c.1149-3del Single submitter
- c.368-59T>C Single submitter
- c.492-11_492-9del Single submitter
- c.492-9dup Single submitter
- c.653-1G>T Single submitter
- c.798+27G>A Single submitter
- c.955+30G>A Single submitter
- c.956-18_956-17del Single submitter
- p.Glu281= Single submitter
Benign/Likely benign 10
- c.367+20T>C Multiple submitters
- c.491+17C>T Multiple submitters inflammatory bowel disease 17
- c.492-9del Multiple submitters inflammatory bowel disease 17
- p.Ala223= Multiple submitters
- p.Arg86Gln Multiple submitters
- p.Pro124= Multiple submitters
- p.Pro220= Multiple submitters
- p.Thr84= Multiple submitters
- p.Tyr158= Multiple submitters
- p.Tyr241= Multiple submitters
Likely benign 157
- c.1149-20G>A Multiple submitters
- c.653-5T>C Multiple submitters
- c.70+20T>A Multiple submitters
- c.955+17A>C Multiple submitters
- c.955+17A>G Multiple submitters
- p.Ala199Val Multiple submitters
- p.Asn200= Multiple submitters
- p.Asp155= Multiple submitters
- p.Ile80= Multiple submitters
- p.Tyr290= Multiple submitters
- c.1045+15C>T Single submitter
- c.1045+16T>G Single submitter
- c.1045+19G>A Single submitter
- c.1045+20G>A Single submitter
- c.1046-19T>A Single submitter
- c.1148+16A>G Single submitter
- c.1149-16C>G Single submitter
- c.1149-17T>C Single submitter
- c.1149-18G>A Single submitter
- c.1149-20G>C Single submitter
- c.1149-7T>A Single submitter
- c.1149-9G>A Single submitter
- c.1239+14_1239+16del Single submitter
- c.1239+16C>T Single submitter
- c.1239+17C>T Single submitter
- c.1240-13C>A Single submitter
- c.1240-15G>A Single submitter
- c.367+12G>T Single submitter
- c.367+13G>A Single submitter
- c.368-11T>G Single submitter
- c.368-12G>T Single submitter
- c.368-13T>C Single submitter
- c.368-16T>C Single submitter
- c.491+13C>T Single submitter
- c.491+8A>G Single submitter
- c.492-11T>G Single submitter
- c.492-13T>G Single submitter
- c.492-14T>C Single submitter
- c.492-15T>C Single submitter
- c.492-17T>G Single submitter
- c.492-8_492-4del Single submitter
- c.492-8G>T Single submitter
- c.492-9T>C Single submitter
- c.652+10A>T Single submitter
- c.652+7A>C Single submitter
- c.653-10_653-5del Single submitter
- c.653-4C>A Single submitter
- c.653-4C>T Single submitter
- c.653-4dup Single submitter
- c.653-8T>C Single submitter
- c.70+16T>C Single submitter
- c.70+17A>T Single submitter
- c.70+8_70+9del Single submitter
- c.798+10A>G Single submitter
- c.798+12T>C Single submitter
- c.798+15C>T Single submitter
- c.798+16A>G Single submitter
- c.798+19del Single submitter
- c.799-12C>T Single submitter
- c.799-17T>C Single submitter
- c.799-6T>C Single submitter
- c.955+14T>C Single submitter
- c.956-16T>C Single submitter
- c.956-19T>C Single submitter
- p.Ala13= Single submitter
- p.Ala201= Single submitter
- p.Ala364= Single submitter
- p.Ala39= Single submitter
- p.Ala55= Single submitter
- p.Arg227= Single submitter
- p.Arg351= Single submitter
- p.Arg461= Single submitter
- p.Arg79= Single submitter
- p.Arg86= Single submitter
- p.Asn262= Single submitter
- p.Asn287= Single submitter
- p.Asn29= Single submitter
- p.Asn407= Single submitter
- p.Asn415= Single submitter
- p.Asn622= Single submitter
- p.Asn69= Single submitter
- p.Asp215= Single submitter
- p.Asp243= Single submitter
- p.Asp479Gly Single submitter
- p.Gln172= Single submitter
- p.Gln76= Single submitter
- p.Glu169= Single submitter
- p.Glu285= Single submitter
- p.Glu37= Single submitter
- p.Glu444= Single submitter
- p.Glu73= Single submitter
- p.Gly188= Single submitter
- p.Gly300= Single submitter
- p.Gly344= Single submitter
- p.Gly70= Single submitter
- p.His313= Single submitter
- p.His33= Single submitter
- p.His445= Single submitter
- p.Ile181= Single submitter
- p.Ile225= Single submitter
- p.Ile361= Single submitter
- p.Ile388= Single submitter
- p.Ile50= Single submitter
- p.Ile504= Single submitter
- p.Ile600= Single submitter
- p.Leu113= Single submitter
- p.Leu202= Single submitter
- p.Leu214= Single submitter
- p.Leu310= Single submitter
- p.Leu412= Single submitter
- p.Leu428= Single submitter
- p.Leu507= Single submitter
- p.Lys314= Single submitter
- p.Lys438= Single submitter
- p.Met573Thr Single submitter
- p.Phe18= Single submitter
- p.Phe469= Single submitter
- p.Phe92= Single submitter
- p.Pro316= Single submitter
- p.Pro443= Single submitter
- p.Pro447= Single submitter
- p.Pro457= Single submitter
- p.Pro457Ser Single submitter
- p.Pro464= Single submitter
- p.Pro561= Single submitter
- p.Pro61= Single submitter
- p.Ser121= Single submitter
- p.Ser185= Single submitter
- p.Ser221= Single submitter
- p.Ser340= Single submitter
- p.Ser371= Single submitter
- p.Ser424= Single submitter
- p.Ser467= Single submitter
- p.Ser518= Single submitter
- p.Ser533= Single submitter
- p.Ser607= Single submitter
- p.Ser625= Single submitter
- p.Thr234= Single submitter
- p.Thr275= Single submitter
- p.Thr331= Single submitter
- p.Thr343= Single submitter
- p.Thr435= Single submitter
- p.Thr505= Single submitter
- p.Tyr136= Single submitter
- p.Tyr192= Single submitter
- p.Tyr276= Single submitter
- p.Val131= Single submitter
- p.Val134= Single submitter
- p.Val218= Single submitter
- p.Val235= Single submitter
- p.Val294= Single submitter
- p.Val567Ile Single submitter
- c.653-5del No assertion criteria IL23R-related disorder
- c.653-5dup No assertion criteria IL23R-related disorder
- c.653-6_653-5del No assertion criteria IL23R-related disorder
- c.653-6_653-5dup No assertion criteria IL23R-related disorder
- c.653-7_653-5del No assertion criteria IL23R-related disorder
Uncertain significance 248
- p.Ala531Thr Multiple submitters ⚠
- p.Cys115Gly Multiple submitters ⚠
- p.Cys558Arg Multiple submitters ⚠
- p.Gln465Pro Multiple submitters ⚠
- p.Gln564Lys Multiple submitters ⚠
- p.Glu169Lys Multiple submitters ⚠
- p.Glu205Val Multiple submitters ⚠
- p.Glu269Gln Multiple submitters ⚠
- p.Gly300Val Multiple submitters
- p.Ile563Met Multiple submitters ⚠
- p.Leu428Pro Multiple submitters ⚠
- p.Lys250Asn Multiple submitters ⚠
- p.Lys452del Multiple submitters
- p.Lys63Glu Multiple submitters ⚠
- p.Pro124Leu Multiple submitters ⚠
- p.Ser19Gly Multiple submitters ⚠
- p.Ser467Leu Multiple submitters ⚠
- p.Ser625Pro Multiple submitters ⚠
- p.Thr132Ile Multiple submitters ⚠
- p.Thr318Ile Multiple submitters ⚠
- p.Thr588Asn Multiple submitters ⚠
- p.Trp242Cys Multiple submitters ⚠
- p.Tyr476Asp Multiple submitters ⚠
- p.Val160Ala Multiple submitters ⚠
- p.Val277Met Multiple submitters ⚠
- c.1149-3T>C Single submitter
- c.1240-3T>C Single submitter
- c.491+5G>A Single submitter
- c.491+6T>C Single submitter
- c.653-15_653-5del Single submitter
- c.70+3_70+4dup Single submitter
- c.70+6G>A Single submitter
- c.955+3G>C Single submitter
- c.956-10T>G Single submitter
- c.956-8G>A Single submitter
- p.Ala10Thr Single submitter ⚠
- p.Ala13Thr Single submitter ⚠
- p.Ala148Gly Single submitter ⚠
- p.Ala201Thr Single submitter ⚠
- p.Ala223Gly Single submitter ⚠
- p.Ala228fs Single submitter
- p.Ala531Val Single submitter ⚠
- p.Ala54Val Single submitter ⚠
- p.Ala55Thr Single submitter ⚠
- p.Arg378Lys Single submitter ⚠
- p.Arg461Lys Single submitter ⚠
- p.Arg461Thr Single submitter ⚠
- p.Arg86Trp Single submitter ⚠
- p.Asn180Ser Single submitter ⚠
- p.Asn266= Single submitter
- p.Asn405fs Single submitter
- p.Asn420Ser Single submitter ⚠
- p.Asn421His Single submitter ⚠
- p.Asn500Asp Single submitter ⚠
- p.Asn502Ser Single submitter ⚠
- p.Asn542Thr Single submitter ⚠
- p.Asn615Ser Single submitter ⚠
- p.Asn91Ser Single submitter ⚠
- p.Asn91Thr Single submitter ⚠
- p.Asp118Asn Single submitter ⚠
- p.Asp118His Single submitter ⚠
- p.Asp129Glu Single submitter ⚠
- p.Asp243Asn Single submitter ⚠
- p.Asp330Glu Single submitter ⚠
- p.Asp431Glu Single submitter
- p.Asp462His Single submitter ⚠
- p.Asp470Asn Single submitter ⚠
- p.Asp479Glu Single submitter ⚠
- p.Asp479His Single submitter ⚠
- p.Asp9fs Single submitter
- p.Asp9Glu Single submitter ⚠
- p.Cys296Tyr Single submitter ⚠
- p.Cys59Arg Single submitter ⚠
- p.Gln171His Single submitter ⚠
- p.Gln245Glu Single submitter ⚠
- p.Gln263Lys Single submitter ⚠
- p.Gln279Glu Single submitter ⚠
- p.Gln3Arg Single submitter ⚠
- p.Gln487His Single submitter ⚠
- p.Gln487Pro Single submitter
- p.Gln525Lys Single submitter ⚠
- p.Gln53His Single submitter ⚠
- p.Gln587Glu Single submitter ⚠
- p.Gln587Ter Single submitter
- p.Gln614Pro Single submitter ⚠
- p.Glu104Gln Single submitter ⚠
- p.Glu206Lys Single submitter ⚠
- p.Glu269Asp Single submitter ⚠
- p.Glu436Ala Single submitter ⚠
- p.Glu459Gln Single submitter ⚠
- p.Glu548Gln Single submitter ⚠
- p.Glu568Lys Single submitter ⚠
- p.Glu582Val Single submitter ⚠
- p.Glu604Asp Single submitter ⚠
- p.Gly140= Single submitter
- p.Gly189Ser Single submitter ⚠
- p.Gly300Asp Single submitter ⚠
- p.Gly355= Single submitter
- p.Gly359Ter Single submitter
- p.Gly383= Single submitter
- p.Gly483Val Single submitter
- p.Gly519Arg Single submitter ⚠
- p.His108Arg Single submitter ⚠
- p.His108Gln Single submitter ⚠
- p.His108Tyr Single submitter ⚠
- p.His161Arg Single submitter ⚠
- p.His329Asn Single submitter ⚠
- p.His329Gln Single submitter ⚠
- p.His33Arg Single submitter ⚠
- p.His345Tyr Single submitter ⚠
- p.Ile114Met Single submitter
- p.Ile16Val Single submitter ⚠
- p.Ile179Thr Single submitter ⚠
- p.Ile219Val Single submitter ⚠
- p.Ile225Val Single submitter ⚠
- p.Ile231Val Single submitter ⚠
- p.Ile239Leu Single submitter ⚠
- p.Ile248Ser Single submitter ⚠
- p.Ile248Thr Single submitter ⚠
- p.Ile248Val Single submitter ⚠
- p.Ile28Thr Single submitter ⚠
- p.Ile341Val Single submitter ⚠
- p.Ile34Leu Single submitter ⚠
- p.Ile354Phe Single submitter ⚠
- p.Ile354Thr Single submitter ⚠
- p.Ile361Thr Single submitter ⚠
- p.Ile369Val Single submitter ⚠
- p.Ile373Phe Single submitter ⚠
- p.Ile373Thr Single submitter ⚠
- p.Ile41Asn Single submitter ⚠
- p.Ile434Thr Single submitter ⚠
- p.Ile434Val Single submitter ⚠
- p.Ile437Lys Single submitter
- p.Ile440Val Single submitter ⚠
- p.Ile50Val Single submitter ⚠
- p.Ile544Val Single submitter ⚠
- p.Ile56Phe Single submitter ⚠
- p.Ile56Val Single submitter ⚠
- p.Ile608Thr Single submitter ⚠
- p.Ile6Ser Single submitter ⚠
- p.Ile71Val Single submitter ⚠
- p.Leu113Pro Single submitter ⚠
- p.Leu151Phe Single submitter ⚠
- p.Leu165Phe Single submitter ⚠
- p.Leu193Phe Single submitter ⚠
- p.Leu193Ser Single submitter ⚠
- p.Leu310Thr Single submitter
- p.Leu367Phe Single submitter ⚠
- p.Leu372_Ile373delinsPhePhe Single submitter
- p.Leu372Phe Single submitter ⚠
- p.Leu389Ser Single submitter ⚠
- p.Leu390Trp Single submitter ⚠
- p.Leu396Phe Single submitter ⚠
- p.Leu492Met Single submitter ⚠
- p.Leu524Ile Single submitter ⚠
- p.Leu87Phe Single submitter ⚠
- p.Lys107Ile Single submitter ⚠
- p.Lys150Thr Single submitter ⚠
- p.Lys157Glu Single submitter ⚠
- p.Lys208fs Single submitter
- p.Lys289Glu Single submitter ⚠
- p.Lys314Glu Single submitter ⚠
- p.Lys385Gln Single submitter ⚠
- p.Lys385Thr Single submitter ⚠
- p.Lys452Thr Single submitter ⚠
- p.Lys485Asn Single submitter ⚠
- p.Lys526Asn Single submitter ⚠
- p.Lys629Glu Single submitter ⚠
- p.Lys63Arg Single submitter ⚠
- p.Lys82Asn Single submitter ⚠
- p.Lys82Ile Single submitter
- p.Met204Leu Single submitter ⚠
- p.Met204Val Single submitter ⚠
- p.Met360Ile Single submitter ⚠
- p.Met411Ile Single submitter ⚠
- p.Met433Leu Single submitter ⚠
- p.Met44Thr Single submitter ⚠
- p.Phe292Leu Single submitter ⚠
- p.Phe594Ile Single submitter ⚠
- p.Phe66Tyr Single submitter
- p.Pro306Ala Single submitter ⚠
- p.Pro306Ser Single submitter ⚠
- p.Pro320Ser Single submitter ⚠
- p.Pro38Thr Single submitter ⚠
- p.Pro443Thr Single submitter ⚠
- p.Pro512Ser Single submitter ⚠
- p.Pro580fs Single submitter
- p.Pro585Ser Single submitter ⚠
- p.Pro95Ser Single submitter ⚠
- p.Ser120Thr Single submitter ⚠
- p.Ser19Asn Single submitter ⚠
- p.Ser221Phe Single submitter ⚠
- p.Ser280Ter Single submitter
- p.Ser308Arg Single submitter ⚠
- p.Ser406= Single submitter
- p.Ser496Gly Single submitter ⚠
- p.Ser499Asn Single submitter ⚠
- p.Ser535= Single submitter
- p.Ser535Ala Single submitter ⚠
- p.Ser559Arg Single submitter ⚠
- p.Ser581Arg Single submitter ⚠
- p.Ser581Thr Single submitter ⚠
- p.Ser619Asn Single submitter ⚠
- p.Ter630Gln Single submitter
- p.Thr145Ile Single submitter ⚠
- p.Thr167Arg Single submitter ⚠
- p.Thr230Ser Single submitter ⚠
- p.Thr261Lys Single submitter ⚠
- p.Thr275Pro Single submitter ⚠
- p.Thr435Lys Single submitter ⚠
- p.Thr448Ala Single submitter ⚠
- p.Thr455Ile Single submitter ⚠
- p.Thr460Ile Single submitter ⚠
- p.Thr472Ile Single submitter ⚠
- p.Thr543Lys Single submitter ⚠
- p.Thr583Pro Single submitter ⚠
- p.Thr610Ala Single submitter ⚠
- p.Trp20Arg Single submitter ⚠
- p.Trp20Leu Single submitter ⚠
- p.Trp20Ter Single submitter
- p.Trp265Ser Single submitter ⚠
- p.Trp35Cys Single submitter ⚠
- p.Trp35Ter Single submitter
- p.Trp395Arg Single submitter ⚠
- p.Tyr173Cys Single submitter ⚠
- p.Tyr173His Single submitter ⚠
- p.Tyr241fs Single submitter
- p.Tyr257Cys Single submitter ⚠
- p.Tyr276Cys Single submitter ⚠
- p.Tyr51His Single submitter ⚠
- p.Val131Ala Single submitter
- p.Val159Glu Single submitter ⚠
- p.Val159Met Single submitter ⚠
- p.Val194Ile Single submitter ⚠
- p.Val251Ile Single submitter ⚠
- p.Val251Leu Single submitter ⚠
- p.Val251Phe Single submitter ⚠
- p.Val267Phe Single submitter ⚠
- p.Val319Ile Single submitter ⚠
- p.Val338Asp Single submitter ⚠
- p.Val36Ile Single submitter ⚠
- p.Val408Ala Single submitter ⚠
- p.Val474Ala Single submitter ⚠
- p.Val474Ile Single submitter ⚠
- p.Val474Phe Single submitter ⚠
- p.Val537Met Single submitter ⚠
- p.Asp399Asn No assertion criteria ⚠
- p.Cys115Tyr No assertion criteria ⚠