ILF2 — 18 ClinVar variants
All ClinVar germline ILF2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 18 flagged for review →
18 Uncertain significance
Full ILF2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 18
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 13
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- ILF2 p.Ala208Gly Uncertain significance Single submitter
- ILF2 p.Ala263Ser Uncertain significance Single submitter
- ILF2 p.Arg319Gln Uncertain significance Single submitter
- ILF2 p.Asn295Thr Uncertain significance Single submitter
- ILF2 p.Asn67Ser Uncertain significance Single submitter
- ILF2 p.Glu383Asp Uncertain significance Single submitter
- ILF2 p.Ile99Val Uncertain significance Single submitter
- ILF2 p.Leu122Val Uncertain significance Single submitter
- ILF2 p.Pro19Leu Uncertain significance Single submitter
- ILF2 p.Pro377Ala Uncertain significance Single submitter
- ILF2 p.Thr179Ala Uncertain significance Single submitter
- ILF2 p.Thr51Ser Uncertain significance Single submitter
- ILF2 p.Val143Leu Uncertain significance Single submitter
Predictors split 5
The independent predictors disagree with each other — read with care.
All ILF2 variants
Uncertain significance 18
- p.Ala208Gly Single submitter ⚠
- p.Ala263Ser Single submitter ⚠
- p.Arg319Gln Single submitter ⚠
- p.Asn295Thr Single submitter ⚠
- p.Asn67Ser Single submitter ⚠
- p.Glu383Asp Single submitter ⚠
- p.Ile99Val Single submitter ⚠
- p.Leu122Val Single submitter ⚠
- p.Pro19Leu Single submitter ⚠
- p.Pro242Ala Single submitter ⚠
- p.Pro377Ala Single submitter ⚠
- p.Pro42Ser Single submitter ⚠
- p.Thr179Ala Single submitter ⚠
- p.Thr51Ser Single submitter ⚠
- p.Tyr251Asp Single submitter ⚠
- p.Tyr251His Single submitter ⚠
- p.Val143Leu Single submitter ⚠
- p.Val44Phe Single submitter ⚠