JUNB — 34 ClinVar variants
All ClinVar germline JUNB variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 34 flagged for review →
34 Uncertain significance
Full JUNB gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 34
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 27
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- JUNB p.Ala161Thr Uncertain significance Single submitter
- JUNB p.Ala161Val Uncertain significance Single submitter
- JUNB p.Ala236Thr Uncertain significance Single submitter
- JUNB p.Ala249Val Uncertain significance Single submitter
- JUNB p.Ala55Asp Uncertain significance Single submitter
- JUNB p.Ala83Ser Uncertain significance Single submitter
- JUNB p.Arg250His Uncertain significance Single submitter
- JUNB p.Asp13Glu Uncertain significance Single submitter
- JUNB p.Asp45Glu Uncertain significance Single submitter
- JUNB p.Glu267Gly Uncertain significance Single submitter
- JUNB p.Gly170Arg Uncertain significance Single submitter
- JUNB p.Gly175Ser Uncertain significance Single submitter
- JUNB p.Gly57Val Uncertain significance Single submitter
- JUNB p.His218Arg Uncertain significance Single submitter
- JUNB p.Ile261Val Uncertain significance Single submitter
- JUNB p.Leu230Pro Uncertain significance Single submitter
- JUNB p.Met329Leu Uncertain significance Single submitter
- JUNB p.Pro165Ala Uncertain significance Single submitter
- JUNB p.Pro169Ser Uncertain significance Single submitter
- JUNB p.Pro221Ser Uncertain significance Single submitter
- JUNB p.Pro227Gln Uncertain significance Single submitter
- JUNB p.Pro227Ser Uncertain significance Single submitter
- JUNB p.Pro37Gln Uncertain significance Single submitter
- JUNB p.Ser67Thr Uncertain significance Single submitter
- JUNB p.Tyr215Phe Uncertain significance Single submitter
- JUNB p.Val152Leu Uncertain significance Single submitter
- JUNB p.Val41Ala Uncertain significance Single submitter
Predictors split 7
The independent predictors disagree with each other — read with care.
- JUNB p.Arg89Leu Uncertain significance Single submitter
- JUNB p.Glu133Lys Uncertain significance Single submitter
- JUNB p.Gly119Glu Uncertain significance Single submitter
- JUNB p.Gly122Arg Uncertain significance Single submitter
- JUNB p.Leu80Phe Uncertain significance Single submitter
- JUNB p.Leu82Arg Uncertain significance Single submitter
- JUNB p.Phe9Ser Uncertain significance Single submitter
All JUNB variants
Uncertain significance 34
- p.Ala161Thr Single submitter ⚠
- p.Ala161Val Single submitter ⚠
- p.Ala236Thr Single submitter ⚠
- p.Ala249Val Single submitter ⚠
- p.Ala55Asp Single submitter ⚠
- p.Ala83Ser Single submitter ⚠
- p.Arg250His Single submitter ⚠
- p.Arg89Leu Single submitter ⚠
- p.Asp13Glu Single submitter ⚠
- p.Asp45Glu Single submitter ⚠
- p.Glu133Lys Single submitter ⚠
- p.Glu267Gly Single submitter ⚠
- p.Gly119Glu Single submitter ⚠
- p.Gly122Arg Single submitter ⚠
- p.Gly170Arg Single submitter ⚠
- p.Gly175Ser Single submitter ⚠
- p.Gly57Val Single submitter ⚠
- p.His218Arg Single submitter ⚠
- p.Ile261Val Single submitter ⚠
- p.Leu230Pro Single submitter ⚠
- p.Leu80Phe Single submitter ⚠
- p.Leu82Arg Single submitter ⚠
- p.Met329Leu Single submitter ⚠
- p.Phe9Ser Single submitter ⚠
- p.Pro165Ala Single submitter ⚠
- p.Pro169Ser Single submitter ⚠
- p.Pro221Ser Single submitter ⚠
- p.Pro227Gln Single submitter ⚠
- p.Pro227Ser Single submitter ⚠
- p.Pro37Gln Single submitter ⚠
- p.Ser67Thr Single submitter ⚠
- p.Tyr215Phe Single submitter ⚠
- p.Val152Leu Single submitter ⚠
- p.Val41Ala Single submitter ⚠