JUND — 59 ClinVar variants
All ClinVar germline JUND variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 54 flagged for review →
1 Benign · 3 Likely benign · 55 Uncertain significance
Full JUND gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 54
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 43
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- JUND p.Ala159Gly Uncertain significance Single submitter
- JUND p.Ala160Thr Uncertain significance Single submitter
- JUND p.Ala163Gly Uncertain significance Single submitter
- JUND p.Ala204Val Uncertain significance Single submitter
- JUND p.Ala216Pro Uncertain significance Single submitter
- JUND p.Ala216Val Uncertain significance Single submitter
- JUND p.Ala26Pro Uncertain significance Single submitter
- JUND p.Ala26Ser Uncertain significance Single submitter
- JUND p.Ala82Val Uncertain significance Single submitter
- JUND p.Ala89Val Uncertain significance Single submitter
- JUND p.Arg235Cys Uncertain significance Single submitter
- JUND p.Asp76Glu Uncertain significance Single submitter
- JUND p.Gln343His Uncertain significance Single submitter
- JUND p.Glu138Asp Uncertain significance Single submitter
- JUND p.Gly171Ala Uncertain significance Single submitter
- JUND p.Gly20Val Uncertain significance Single submitter
- JUND p.Gly86Arg Uncertain significance Single submitter
- JUND p.His148Pro Uncertain significance Single submitter
- JUND p.Ile261Val Uncertain significance Single submitter
- JUND p.Leu31Val Uncertain significance Single submitter
- JUND p.Leu73Arg Uncertain significance Single submitter
- JUND p.Lys287Arg Uncertain significance Single submitter
- JUND p.Pro169Leu Uncertain significance Single submitter
- JUND p.Pro178Ser Uncertain significance Single submitter
- JUND p.Pro189Ala Uncertain significance Single submitter
- JUND p.Pro223Leu Uncertain significance Single submitter
- JUND p.Pro228Ala Uncertain significance Single submitter
- JUND p.Pro345Ser Uncertain significance Single submitter
- JUND p.Pro69Leu Uncertain significance Single submitter
- JUND p.Pro72His Uncertain significance Single submitter
- JUND p.Pro84Ser Uncertain significance Single submitter
- JUND p.Ser120Thr Uncertain significance Single submitter
- JUND p.Ser198Asn Uncertain significance Single submitter
- JUND p.Ser199Asn Uncertain significance Single submitter
- JUND p.Ser53Asn Uncertain significance Single submitter
- JUND p.Thr172Ala Uncertain significance Single submitter
- JUND p.Thr172Met Uncertain significance Single submitter
- JUND p.Thr174Pro Uncertain significance Single submitter
- JUND p.Thr313Met Uncertain significance Single submitter
- JUND p.Thr38Pro Uncertain significance Single submitter
- JUND p.Thr3Ile Uncertain significance Single submitter
- JUND p.Thr71Ile Uncertain significance Single submitter
- JUND p.Tyr200Cys Uncertain significance Single submitter
Predictors split 11
The independent predictors disagree with each other — read with care.
- JUND p.Ala161Thr Uncertain significance Single submitter
- JUND p.Ala163Ser Uncertain significance Single submitter
- JUND p.Gln343Glu Uncertain significance Single submitter
- JUND p.Gly205Glu Uncertain significance Single submitter
- JUND p.Gly206Asp Uncertain significance Single submitter
- JUND p.Ile269Met Uncertain significance Single submitter
- JUND p.Leu339Pro Uncertain significance Single submitter
- JUND p.Leu54Gln Uncertain significance Single submitter
- JUND p.Lys127Thr Uncertain significance Single submitter
- JUND p.Lys47Asn Uncertain significance Single submitter
- JUND p.Pro225Leu Uncertain significance Single submitter
All JUND variants
Benign 1
- p.Arg275= Single submitter
Likely benign 3
- p.Ala89= Single submitter
- p.Leu197= Single submitter
- p.Ser121Thr Single submitter
Uncertain significance 55
- p.Ala159Gly Single submitter ⚠
- p.Ala160Thr Single submitter ⚠
- p.Ala161Thr Single submitter ⚠
- p.Ala163Gly Single submitter ⚠
- p.Ala163Ser Single submitter ⚠
- p.Ala204Val Single submitter ⚠
- p.Ala216Pro Single submitter ⚠
- p.Ala216Val Single submitter ⚠
- p.Ala26Pro Single submitter ⚠
- p.Ala26Ser Single submitter ⚠
- p.Ala82Val Single submitter ⚠
- p.Ala89Val Single submitter ⚠
- p.Arg235Cys Single submitter ⚠
- p.Asp76Glu Single submitter ⚠
- p.Gln326Arg Single submitter
- p.Gln343Glu Single submitter ⚠
- p.Gln343His Single submitter ⚠
- p.Glu138Asp Single submitter ⚠
- p.Gly171Ala Single submitter ⚠
- p.Gly205Glu Single submitter ⚠
- p.Gly206Asp Single submitter ⚠
- p.Gly20Val Single submitter ⚠
- p.Gly86Arg Single submitter ⚠
- p.His148Pro Single submitter ⚠
- p.Ile261Val Single submitter ⚠
- p.Ile269Met Single submitter ⚠
- p.Leu31Val Single submitter ⚠
- p.Leu339Pro Single submitter ⚠
- p.Leu54Gln Single submitter ⚠
- p.Leu73Arg Single submitter ⚠
- p.Lys127Thr Single submitter ⚠
- p.Lys287Arg Single submitter ⚠
- p.Lys47Asn Single submitter ⚠
- p.Pro169Leu Single submitter ⚠
- p.Pro178Ser Single submitter ⚠
- p.Pro189Ala Single submitter ⚠
- p.Pro223Leu Single submitter ⚠
- p.Pro225Leu Single submitter ⚠
- p.Pro228Ala Single submitter ⚠
- p.Pro345Ser Single submitter ⚠
- p.Pro69Leu Single submitter ⚠
- p.Pro72His Single submitter ⚠
- p.Pro84Ser Single submitter ⚠
- p.Ser120Thr Single submitter ⚠
- p.Ser198Asn Single submitter ⚠
- p.Ser199Asn Single submitter ⚠
- p.Ser53Asn Single submitter ⚠
- p.Thr172Ala Single submitter ⚠
- p.Thr172Met Single submitter ⚠
- p.Thr174Pro Single submitter ⚠
- p.Thr313Met Single submitter ⚠
- p.Thr38Pro Single submitter ⚠
- p.Thr3Ile Single submitter ⚠
- p.Thr71Ile Single submitter ⚠
- p.Tyr200Cys Single submitter ⚠