Sugi Variant

Sugi Variant/LRRK2

LRRK2 — 3812 ClinVar variants

All ClinVar germline LRRK2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 2181 flagged for review →

7 Pathogenic · 1 Pathogenic/Likely pathogenic · 2 Likely pathogenic · 57 Conflicting · 167 Benign · 47 Benign/Likely benign · 1173 Likely benign · 2358 Uncertain significance

Full LRRK2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 2181

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors vs ClinVar 4

ClinVar calls these pathogenic, but the computational predictors lean tolerated — the highest-value review flag.

Predictors agree, ClinVar conflicts 32

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 1715

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 1715

Predictors split 430

The independent predictors disagree with each other — read with care. · showing the 150 best-reviewed of 430

All LRRK2 variants

Pathogenic 7

Pathogenic/Likely pathogenic 1

Likely pathogenic 2

Conflicting classifications of pathogenicity 57

  • c.2070+9T>A Single submitter autosomal dominant Parkinson disease 8
  • c.347+2T>C Single submitter autosomal dominant Parkinson disease 8
  • c.3777+7C>T Single submitter autosomal dominant Parkinson disease 8
  • c.4536+3A>G Single submitter autosomal dominant Parkinson disease 8
  • c.5948+8G>C Single submitter autosomal dominant Parkinson disease 8
  • c.7029-3T>C Single submitter autosomal dominant Parkinson disease 8
  • c.839-4T>G Single submitter autosomal dominant Parkinson disease 8
  • c.*1402G>T Single submitter autosomal dominant Parkinson disease 8
  • p.Ala211Val Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Ala307= Single submitter Inborn genetic diseases
  • p.Ala920Thr Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg1282Ser Single submitter Inborn genetic diseases ⚠
  • p.Arg1320Ser Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg1325Gln Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg1628His Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg1628Pro Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg1725= Single submitter autosomal dominant Parkinson disease 8
  • p.Arg1725Ter Single submitter autosomal dominant Parkinson disease 8
  • p.Arg2143His Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg2446His Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg2477Gln Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg521Gly Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Arg767His Single submitter vascular parkinsonism ⚠
  • p.Arg793Met Single submitter autosomal dominant Parkinson disease 8
  • p.Asn1437Ser Single submitter Parkinson disease ⚠
  • p.Asn202= Single submitter Inborn genetic diseases
  • p.Asn551Lys Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Asn59Lys Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Gln1323= Single submitter Inborn genetic diseases
  • p.Gln1648Arg Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Gln923His Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Glu334Lys Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Glu447= Single submitter autosomal dominant Parkinson disease 8
  • p.Gly2432= Single submitter Inborn genetic diseases
  • p.His442Tyr Single submitter Inborn genetic diseases ⚠
  • p.His942= Single submitter Inborn genetic diseases
  • p.Ile1371Val Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Ile1933= Single submitter Inborn genetic diseases
  • p.Leu119Pro Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Leu286Val Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Lys182= Single submitter Inborn genetic diseases
  • p.Met1057Ile Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Met1869Thr Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Met262Val Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Met704Val Single submitter Inborn genetic diseases ⚠
  • p.Ser1228Thr Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Thr2141Met Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Thr2267= Single submitter Inborn genetic diseases
  • p.Thr2310Ala Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Thr2310Met Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Thr2356Ile Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Thr358Met Single submitter Inborn genetic diseases ⚠
  • p.Tyr2189Cys Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Tyr2346His Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Val1905Leu Single submitter autosomal dominant Parkinson disease 8 ⚠
  • p.Val2194= Single submitter autosomal dominant Parkinson disease 8
  • p.Val2296Ile Single submitter autosomal dominant Parkinson disease 8 ⚠

Benign 167

Benign/Likely benign 47

  • c.1182-4A>G Multiple submitters autosomal dominant Parkinson disease 8
  • c.1802-11dup Multiple submitters autosomal dominant Parkinson disease 8
  • c.2689+19_2689+20dup Multiple submitters autosomal dominant Parkinson disease 8
  • c.2689+20dup Multiple submitters autosomal dominant Parkinson disease 8
  • c.3778-9C>T Multiple submitters autosomal dominant Parkinson disease 8
  • c.4318-6C>T Multiple submitters autosomal dominant Parkinson disease 8
  • c.5509+20A>C Multiple submitters autosomal dominant Parkinson disease 8
  • c.5510-9A>G Multiple submitters autosomal dominant Parkinson disease 8
  • c.6281-3dup Multiple submitters autosomal dominant Parkinson disease 8
  • c.6844-14_6844-13insA Multiple submitters autosomal dominant Parkinson disease 8
  • c.6844-9_6844-8dup Multiple submitters autosomal dominant Parkinson disease 8
  • c.7462+15G>C Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala419Val Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala774= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg1398His Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg1514Gln Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg2477Trp Multiple submitters autosomal dominant Parkinson disease 8
  • p.Asn2047= Multiple submitters Inborn genetic diseases
  • p.Asn2081Asp Multiple submitters vascular parkinsonism
  • p.Asn289= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Gln1111His Multiple submitters autosomal dominant Parkinson disease 8
  • p.Gln116Arg Multiple submitters autosomal dominant Parkinson disease 8
  • p.Gln2022= Multiple submitters Inborn genetic diseases
  • p.Glu1537= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Glu899Asp Multiple submitters autosomal dominant Parkinson disease 8 ⚠
  • p.Gly2170= Multiple submitters Inborn genetic diseases
  • p.Gly2385= Multiple submitters autosomal dominant Parkinson disease 8
  • p.His115Pro Multiple submitters autosomal dominant Parkinson disease 8
  • p.His365= Multiple submitters Inborn genetic diseases
  • p.Leu1114= Multiple submitters Inborn genetic diseases
  • p.Leu1694= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu1795= Multiple submitters Inborn genetic diseases
  • p.Leu761= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Met1646Thr Multiple submitters autosomal dominant Parkinson disease 8
  • p.Pro1262Ala Multiple submitters autosomal dominant Parkinson disease 8
  • p.Pro1542Ser Multiple submitters autosomal dominant Parkinson disease 8
  • p.Pro755Leu Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser1143= Multiple submitters Inborn genetic diseases
  • p.Ser2440= Multiple submitters Inborn genetic diseases
  • p.Ser865Phe Multiple submitters autosomal dominant Parkinson disease 8
  • p.Thr1410Met Multiple submitters autosomal dominant Parkinson disease 8 ⚠
  • p.Thr278= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Tyr2018= Multiple submitters Inborn genetic diseases
  • p.Val2495Ile Multiple submitters autosomal dominant Parkinson disease 8
  • p.Val674= Multiple submitters Inborn genetic diseases
  • p.Val868= Multiple submitters Inborn genetic diseases
  • p.Val921Ile Multiple submitters autosomal dominant Parkinson disease 8

Likely benign 1173

Showing the top 300 by review status; the full set is in the sitemap.

  • c.1418+129T>C Multiple submitters
  • c.1656+165A>C Multiple submitters
  • c.237+20T>A Multiple submitters autosomal dominant Parkinson disease 8
  • c.2689+12A>G Multiple submitters autosomal dominant Parkinson disease 8
  • c.2879-44A>G Multiple submitters
  • c.3096+119G>A Multiple submitters
  • c.347+193A>T Multiple submitters
  • c.437-44T>G Multiple submitters
  • c.5171-9A>G Multiple submitters autosomal dominant Parkinson disease 8
  • c.5657-46C>T Multiple submitters
  • c.572-14C>T Multiple submitters autosomal dominant Parkinson disease 8
  • c.5758-143A>T Multiple submitters
  • c.6382-37C>T Multiple submitters
  • c.6576+44T>C Multiple submitters
  • c.6844-49C>T Multiple submitters
  • c.706+10A>C Multiple submitters autosomal dominant Parkinson disease 8
  • c.7391-177A>G Multiple submitters
  • c.*1429C>G Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala1430= Multiple submitters Inborn genetic diseases
  • p.Ala1726= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala183= Multiple submitters Inborn genetic diseases
  • p.Ala1897= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala1950= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala211= Multiple submitters Inborn genetic diseases
  • p.Ala2285= Multiple submitters Inborn genetic diseases
  • p.Ala2286= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala233= Multiple submitters Inborn genetic diseases
  • p.Ala369= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala504= Multiple submitters Inborn genetic diseases
  • p.Ala576= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ala660= Multiple submitters Inborn genetic diseases
  • p.Ala716= Multiple submitters Inborn genetic diseases
  • p.Ala795= Multiple submitters Inborn genetic diseases
  • p.Ala851= Multiple submitters Inborn genetic diseases
  • p.Ala857= Multiple submitters Inborn genetic diseases
  • p.Ala920= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg1325= Multiple submitters Inborn genetic diseases
  • p.Arg1381= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg1386= Multiple submitters Inborn genetic diseases
  • p.Arg1441= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg1483= Multiple submitters Inborn genetic diseases
  • p.Arg1538= Multiple submitters Inborn genetic diseases
  • p.Arg1915= Multiple submitters Inborn genetic diseases
  • p.Arg22= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Arg506Gln Multiple submitters autosomal dominant Parkinson disease 8
  • p.Asn1506= Multiple submitters Inborn genetic diseases
  • p.Asn2149= Multiple submitters Inborn genetic diseases
  • p.Asn25= Multiple submitters Inborn genetic diseases
  • p.Asn693= Multiple submitters Inborn genetic diseases
  • p.Asp1818= Multiple submitters Inborn genetic diseases
  • p.Asp1863= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Asp1994= Multiple submitters Inborn genetic diseases
  • p.Asp861= Multiple submitters Inborn genetic diseases
  • p.Cys2389= Multiple submitters Inborn genetic diseases
  • p.Gln1516= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Gln1823Lys Multiple submitters autosomal dominant Parkinson disease 8
  • p.Glu1280= Multiple submitters Inborn genetic diseases
  • p.Glu1400= Multiple submitters Inborn genetic diseases
  • p.Glu1899= Multiple submitters Inborn genetic diseases
  • p.Glu522= Multiple submitters Inborn genetic diseases
  • p.Gly1289= Multiple submitters Inborn genetic diseases
  • p.Gly1722= Multiple submitters Inborn genetic diseases
  • p.Gly1804= Multiple submitters Inborn genetic diseases
  • p.Gly1886= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Gly1939= Multiple submitters Inborn genetic diseases
  • p.Gly1981= Multiple submitters Inborn genetic diseases
  • p.Gly2028= Multiple submitters Inborn genetic diseases
  • p.Gly2070= Multiple submitters Inborn genetic diseases
  • p.Gly2284= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Gly859= Multiple submitters Inborn genetic diseases
  • p.Gly937= Multiple submitters autosomal dominant Parkinson disease 8
  • p.His1197= Multiple submitters Inborn genetic diseases
  • p.His1571= Multiple submitters Inborn genetic diseases
  • p.His1977= Multiple submitters autosomal dominant Parkinson disease 8
  • p.His468= Multiple submitters Inborn genetic diseases
  • p.His61= Multiple submitters Inborn genetic diseases
  • p.Ile2354= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ile38= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu1010= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu1302= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu1449= Multiple submitters Inborn genetic diseases
  • p.Leu1652= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu1917= Multiple submitters Inborn genetic diseases
  • p.Leu2238= Multiple submitters Inborn genetic diseases
  • p.Leu229= Multiple submitters Inborn genetic diseases
  • p.Leu23= Multiple submitters Inborn genetic diseases
  • p.Leu2300= Multiple submitters Inborn genetic diseases
  • p.Leu2507= Multiple submitters Inborn genetic diseases
  • p.Leu54= Multiple submitters Inborn genetic diseases
  • p.Leu631= Multiple submitters Inborn genetic diseases
  • p.Leu665= Multiple submitters Inborn genetic diseases
  • p.Leu673= Multiple submitters Inborn genetic diseases
  • p.Leu731= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu757= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu762= Multiple submitters Inborn genetic diseases
  • p.Leu790= Multiple submitters Inborn genetic diseases
  • p.Leu791= Multiple submitters Inborn genetic diseases
  • p.Leu794= Multiple submitters Inborn genetic diseases
  • p.Leu839= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Leu922= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Lys1290= Multiple submitters Inborn genetic diseases
  • p.Lys1359= Multiple submitters Inborn genetic diseases
  • p.Lys1605= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Lys2234= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Lys2485= Multiple submitters Inborn genetic diseases
  • p.Lys364= Multiple submitters Inborn genetic diseases
  • p.Lys492= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Phe1401= Multiple submitters Inborn genetic diseases
  • p.Phe260= Multiple submitters Inborn genetic diseases
  • p.Phe348= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Phe699= Multiple submitters Inborn genetic diseases
  • p.Pro1212= Multiple submitters Inborn genetic diseases
  • p.Pro1331= Multiple submitters Inborn genetic diseases
  • p.Pro1446Leu Multiple submitters autosomal dominant Parkinson disease 8
  • p.Pro1546= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Pro1588= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Pro1642= Multiple submitters Inborn genetic diseases
  • p.Pro1793= Multiple submitters Inborn genetic diseases
  • p.Pro2095= Multiple submitters Inborn genetic diseases
  • p.Pro2103= Multiple submitters Inborn genetic diseases
  • p.Pro303= Multiple submitters Inborn genetic diseases
  • p.Ser1052= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser1145= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser1467= Multiple submitters Inborn genetic diseases
  • p.Ser1627= Multiple submitters Inborn genetic diseases
  • p.Ser1647= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser1721= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser231= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser2454= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser455= Multiple submitters Inborn genetic diseases
  • p.Ser634= Multiple submitters Inborn genetic diseases
  • p.Ser681= Multiple submitters Inborn genetic diseases
  • p.Ser743= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser764= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Ser827= Multiple submitters Inborn genetic diseases
  • p.Ser958= Multiple submitters Inborn genetic diseases
  • p.Thr1410= Multiple submitters Inborn genetic diseases
  • p.Thr1491= Multiple submitters Inborn genetic diseases
  • p.Thr15= Multiple submitters Inborn genetic diseases
  • p.Thr2004= Multiple submitters Inborn genetic diseases
  • p.Thr2141= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Thr2229= Multiple submitters Inborn genetic diseases
  • p.Thr2310= Multiple submitters Inborn genetic diseases
  • p.Thr46= Multiple submitters Inborn genetic diseases
  • p.Thr776= Multiple submitters Inborn genetic diseases
  • p.Thr838= Multiple submitters Inborn genetic diseases
  • p.Tyr1718= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Tyr1739= Multiple submitters Inborn genetic diseases
  • p.Tyr2057= Multiple submitters Inborn genetic diseases
  • p.Tyr2364= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Tyr250= Multiple submitters Inborn genetic diseases
  • p.Tyr707= Multiple submitters Inborn genetic diseases
  • p.Val1247= Multiple submitters Inborn genetic diseases
  • p.Val1389= Multiple submitters Inborn genetic diseases
  • p.Val1615= Multiple submitters Inborn genetic diseases
  • p.Val21= Multiple submitters Inborn genetic diseases
  • p.Val2128= Multiple submitters Inborn genetic diseases
  • p.Val2357= Multiple submitters autosomal dominant Parkinson disease 8
  • p.Val490= Multiple submitters Inborn genetic diseases
  • p.Val62= Multiple submitters Inborn genetic diseases
  • c.1101+12A>G Single submitter autosomal dominant Parkinson disease 8
  • c.1181+244T>C Single submitter
  • c.1182-5G>A Single submitter autosomal dominant Parkinson disease 8
  • c.1288+12G>A Single submitter autosomal dominant Parkinson disease 8
  • c.1288+17G>A Single submitter autosomal dominant Parkinson disease 8
  • c.1288+9T>A Single submitter autosomal dominant Parkinson disease 8
  • c.1289-248_1289-246del Single submitter
  • c.1289-333C>T Single submitter
  • c.1418+6A>G Single submitter
  • c.1419-286C>T Single submitter
  • c.151+19A>G Single submitter autosomal dominant Parkinson disease 8
  • c.151+20C>T Single submitter autosomal dominant Parkinson disease 8
  • c.1543+18T>C Single submitter autosomal dominant Parkinson disease 8
  • c.1543+283C>A Single submitter
  • c.1656+171A>G Single submitter
  • c.1657-20G>A Single submitter autosomal dominant Parkinson disease 8
  • c.1801+10A>G Single submitter autosomal dominant Parkinson disease 8
  • c.1801+15A>T Single submitter autosomal dominant Parkinson disease 8
  • c.1941+15T>C Single submitter autosomal dominant Parkinson disease 8
  • c.1941+39C>T Single submitter
  • c.1942-114T>C Single submitter
  • c.2071-12C>T Single submitter autosomal dominant Parkinson disease 8
  • c.2241+14G>A Single submitter autosomal dominant Parkinson disease 8
  • c.2241+19A>C Single submitter
  • c.237+239A>G Single submitter
  • c.238-278G>T Single submitter
  • c.2500+166C>T Single submitter
  • c.2500+211G>C Single submitter
  • c.2500+9C>T Single submitter autosomal dominant Parkinson disease 8
  • c.2501-11C>T Single submitter autosomal dominant Parkinson disease 8
  • c.2501-13C>T Single submitter autosomal dominant Parkinson disease 8
  • c.2689+12A>T Single submitter autosomal dominant Parkinson disease 8
  • c.2689+15A>T Single submitter autosomal dominant Parkinson disease 8
  • c.2689+17A>G Single submitter autosomal dominant Parkinson disease 8
  • c.2689+20A>C Single submitter autosomal dominant Parkinson disease 8
  • c.2689+73A>G Single submitter
  • c.2690-14C>A Single submitter autosomal dominant Parkinson disease 8
  • c.2808+232_2808+233insTATA Single submitter
  • c.2808+232_2808+233insTATATATATATA Single submitter
  • c.2809-18T>C Single submitter autosomal dominant Parkinson disease 8
  • c.2809-19A>G Single submitter autosomal dominant Parkinson disease 8
  • c.2878+14T>C Single submitter autosomal dominant Parkinson disease 8
  • c.3347+286AT[11] Single submitter
  • c.3347+306_3347+307insTATATATAAATA Single submitter
  • c.3348-20A>T Single submitter autosomal dominant Parkinson disease 8
  • c.347+11T>C Single submitter autosomal dominant Parkinson disease 8
  • c.347+13G>A Single submitter autosomal dominant Parkinson disease 8
  • c.347+16A>G Single submitter autosomal dominant Parkinson disease 8
  • c.347+20A>G Single submitter autosomal dominant Parkinson disease 8
  • c.3496+18G>A Single submitter autosomal dominant Parkinson disease 8
  • c.3497-277T>G Single submitter
  • c.3591-14G>C Single submitter autosomal dominant Parkinson disease 8
  • c.3777+13T>C Single submitter autosomal dominant Parkinson disease 8
  • c.3777+257A>T Single submitter
  • c.3777+8G>A Single submitter autosomal dominant Parkinson disease 8
  • c.3777+8G>T Single submitter
  • c.3777+9A>G Single submitter autosomal dominant Parkinson disease 8
  • c.3778-355del Single submitter
  • c.3778-7del Single submitter
  • c.3959+9A>T Single submitter autosomal dominant Parkinson disease 8
  • c.3960-310A>T Single submitter
  • c.3960-5A>G Single submitter autosomal dominant Parkinson disease 8
  • c.4189+14T>C Single submitter autosomal dominant Parkinson disease 8
  • c.4189+155C>T Single submitter
  • c.4190-5T>C Single submitter autosomal dominant Parkinson disease 8
  • c.4318-182C>T Single submitter
  • c.4318-211G>A Single submitter
  • c.436+11T>C Single submitter autosomal dominant Parkinson disease 8
  • c.436+120T>A Single submitter
  • c.436+15T>C Single submitter autosomal dominant Parkinson disease 8
  • c.436+231C>T Single submitter
  • c.4536+20G>A Single submitter autosomal dominant Parkinson disease 8
  • c.4536+7T>C Single submitter autosomal dominant Parkinson disease 8
  • c.4537-10A>C Single submitter autosomal dominant Parkinson disease 8
  • c.4537-17C>A Single submitter autosomal dominant Parkinson disease 8
  • c.4537-256C>A Single submitter
  • c.4738+14G>A Single submitter autosomal dominant Parkinson disease 8
  • c.4739-4A>G Single submitter autosomal dominant Parkinson disease 8
  • c.4739-5T>C Single submitter autosomal dominant Parkinson disease 8
  • c.4827+249T>C Single submitter
  • c.4827+6T>A Single submitter autosomal dominant Parkinson disease 8
  • c.4827+7G>C Single submitter autosomal dominant Parkinson disease 8
  • c.4827+9C>T Single submitter autosomal dominant Parkinson disease 8
  • c.4828-11G>A Single submitter autosomal dominant Parkinson disease 8
  • c.4828-17T>C Single submitter autosomal dominant Parkinson disease 8
  • c.5016-225G>A Single submitter
  • c.5170+14_5170+28del Single submitter autosomal dominant Parkinson disease 8
  • c.5171-95G>T Single submitter
  • c.5317+59A>C Single submitter
  • c.5317+68dup Single submitter
  • c.5318-4G>A Single submitter autosomal dominant Parkinson disease 8
  • c.5510-15T>C Single submitter autosomal dominant Parkinson disease 8
  • c.5510-19A>C Single submitter autosomal dominant Parkinson disease 8
  • c.5657-268A>G Single submitter
  • c.5657-81A>G Single submitter
  • c.5657-9T>C Single submitter autosomal dominant Parkinson disease 8
  • c.571+16A>C Single submitter autosomal dominant Parkinson disease 8
  • c.571+18del Single submitter autosomal dominant Parkinson disease 8
  • c.5758-10A>G Single submitter autosomal dominant Parkinson disease 8
  • c.5758-11G>A Single submitter autosomal dominant Parkinson disease 8
  • c.5758-14T>C Single submitter autosomal dominant Parkinson disease 8
  • c.5948+202T>C Single submitter
  • c.5948+34T>C Single submitter
  • c.6109+12G>A Single submitter autosomal dominant Parkinson disease 8
  • c.6109+14T>C Single submitter autosomal dominant Parkinson disease 8
  • c.6109+19C>T Single submitter autosomal dominant Parkinson disease 8
  • c.6110-8A>G Single submitter autosomal dominant Parkinson disease 8
  • c.6280+14T>C Single submitter autosomal dominant Parkinson disease 8
  • c.6381+16T>G Single submitter autosomal dominant Parkinson disease 8
  • c.6382-5C>A Single submitter
  • c.6382-8T>C Single submitter autosomal dominant Parkinson disease 8
  • c.6576+242A>T Single submitter
  • c.6577-292G>C Single submitter
  • c.6577-57T>C Single submitter
  • c.6771-15del Single submitter autosomal dominant Parkinson disease 8
  • c.6843+12A>G Single submitter autosomal dominant Parkinson disease 8
  • c.6843+206A>C Single submitter
  • c.6843+229T>A Single submitter
  • c.6843+8T>C Single submitter autosomal dominant Parkinson disease 8
  • c.6844-15_6844-14insC Single submitter autosomal dominant Parkinson disease 8
  • c.6844-7G>T Single submitter autosomal dominant Parkinson disease 8
  • c.6844-8del Single submitter
  • c.7029-10T>C Single submitter autosomal dominant Parkinson disease 8
  • c.7029-16T>A Single submitter autosomal dominant Parkinson disease 8
  • c.7029-4G>T Single submitter autosomal dominant Parkinson disease 8
  • c.706+3A>G Single submitter
  • c.707-13T>C Single submitter autosomal dominant Parkinson disease 8
  • c.707-14C>T Single submitter autosomal dominant Parkinson disease 8
  • c.707-15T>A Single submitter autosomal dominant Parkinson disease 8
  • c.707-58C>T Single submitter
  • c.7181+125A>G Single submitter
  • c.7463-15T>C Single submitter
  • c.7463-8T>C Single submitter autosomal dominant Parkinson disease 8
  • c.838+10T>A Single submitter autosomal dominant Parkinson disease 8
  • c.838+177T>C Single submitter
  • c.958+17A>G Single submitter
  • c.958+323G>A Single submitter
  • c.959-13A>C Single submitter autosomal dominant Parkinson disease 8
  • c.959-216del Single submitter
  • c.959-5T>C Single submitter autosomal dominant Parkinson disease 8

Uncertain significance 2358

Showing the top 300 by review status; the full set is in the sitemap.