MAP3K6 — 254 ClinVar variants
All ClinVar germline MAP3K6 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 190 flagged for review →
1 Likely pathogenic · 16 Benign · 2 Benign/Likely benign · 36 Likely benign · 199 Uncertain significance
Full MAP3K6 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 190
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 164
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 164
- MAP3K6 p.Ala1029Val Uncertain significance Single submitter
- MAP3K6 p.Ala113Ser Uncertain significance Single submitter
- MAP3K6 p.Ala1208Val Uncertain significance Single submitter
- MAP3K6 p.Ala151Asp Uncertain significance Single submitter
- MAP3K6 p.Ala151Val Uncertain significance Single submitter
- MAP3K6 p.Ala246Val Uncertain significance Single submitter
- MAP3K6 p.Ala302Asp Uncertain significance Single submitter
- MAP3K6 p.Ala332Val Uncertain significance Single submitter
- MAP3K6 p.Ala372Thr Uncertain significance Single submitter
- MAP3K6 p.Ala40Ser Uncertain significance Single submitter
- MAP3K6 p.Ala447Ser Uncertain significance Single submitter
- MAP3K6 p.Ala451Val Uncertain significance Single submitter
- MAP3K6 p.Ala573Ser Uncertain significance Single submitter
- MAP3K6 p.Ala695Thr Uncertain significance Single submitter
- MAP3K6 p.Ala78Val Uncertain significance Single submitter
- MAP3K6 p.Ala897Thr Uncertain significance Single submitter
- MAP3K6 p.Ala930Val Uncertain significance Single submitter
- MAP3K6 p.Arg1033Gly Uncertain significance Single submitter
- MAP3K6 p.Arg1078Ser Uncertain significance Single submitter
- MAP3K6 p.Arg1113Gln Uncertain significance Single submitter
- MAP3K6 p.Arg1185Gln Uncertain significance Single submitter
- MAP3K6 p.Arg1197Gly Uncertain significance Single submitter
- MAP3K6 p.Arg1261Cys Uncertain significance Single submitter
- MAP3K6 p.Arg1261His Uncertain significance Single submitter
- MAP3K6 p.Arg1269His Uncertain significance Single submitter
- MAP3K6 p.Arg1269Pro Uncertain significance Single submitter
- MAP3K6 p.Arg1278Gln Uncertain significance Single submitter
- MAP3K6 p.Arg186Gln Uncertain significance Single submitter
- MAP3K6 p.Arg219Gln Uncertain significance Single submitter
- MAP3K6 p.Arg219Gly Uncertain significance Single submitter
- MAP3K6 p.Arg222Cys Uncertain significance Single submitter
- MAP3K6 p.Arg240Trp Uncertain significance Single submitter
- MAP3K6 p.Arg241Trp Uncertain significance Single submitter
- MAP3K6 p.Arg244Trp Uncertain significance Single submitter
- MAP3K6 p.Arg256Gln Uncertain significance Single submitter
- MAP3K6 p.Arg264Gln Uncertain significance Single submitter
- MAP3K6 p.Arg27Gln Uncertain significance Single submitter
- MAP3K6 p.Arg285His Uncertain significance Single submitter
- MAP3K6 p.Arg331Gln Uncertain significance Single submitter
- MAP3K6 p.Arg331Trp Uncertain significance Single submitter
- MAP3K6 p.Arg37Gly Uncertain significance Single submitter
- MAP3K6 p.Arg488Lys Uncertain significance Single submitter
- MAP3K6 p.Arg544Gly Uncertain significance Single submitter
- MAP3K6 p.Arg544Trp Uncertain significance Single submitter
- MAP3K6 p.Arg586Cys Uncertain significance Single submitter
- MAP3K6 p.Arg62Pro Uncertain significance Single submitter
- MAP3K6 p.Arg73His Uncertain significance Single submitter
- MAP3K6 p.Arg753His Uncertain significance Single submitter
- MAP3K6 p.Arg796Gly Uncertain significance Single submitter
- MAP3K6 p.Arg824His Uncertain significance Single submitter
- MAP3K6 p.Arg846Cys Uncertain significance Single submitter
- MAP3K6 p.Arg86Gln Uncertain significance Single submitter
- MAP3K6 p.Arg892His Uncertain significance Single submitter
- MAP3K6 p.Arg911Met Uncertain significance Single submitter
- MAP3K6 p.Arg913Cys Uncertain significance Single submitter
- MAP3K6 p.Arg923Trp Uncertain significance Single submitter
- MAP3K6 p.Arg961Ser Uncertain significance Single submitter
- MAP3K6 p.Asn143His Uncertain significance Single submitter
- MAP3K6 p.Asn397Ser Uncertain significance Single submitter
- MAP3K6 p.Asn937Lys Uncertain significance Single submitter
- MAP3K6 p.Asp1085Val Uncertain significance Single submitter
- MAP3K6 p.Asp1140Tyr Uncertain significance Single submitter
- MAP3K6 p.Asp1231Gly Uncertain significance Single submitter
- MAP3K6 p.Asp1231His Uncertain significance Single submitter
- MAP3K6 p.Asp1255Val Uncertain significance Single submitter
- MAP3K6 p.Asp152Asn Uncertain significance Single submitter
- MAP3K6 p.Asp169Asn Uncertain significance Single submitter
- MAP3K6 p.Asp351Asn Uncertain significance Single submitter
- MAP3K6 p.Asp523His Uncertain significance Single submitter
- MAP3K6 p.Asp743Glu Uncertain significance Single submitter
- MAP3K6 p.Cys588Tyr Uncertain significance Single submitter
- MAP3K6 p.Gln1010Arg Uncertain significance Single submitter
- MAP3K6 p.Gln1025Glu Uncertain significance Single submitter
- MAP3K6 p.Gln1095His Uncertain significance Single submitter
- MAP3K6 p.Gln1157Arg Uncertain significance Single submitter
- MAP3K6 p.Gln1165His Uncertain significance Single submitter
- MAP3K6 p.Gln1219Glu Uncertain significance Single submitter
- MAP3K6 p.Gln157Arg Uncertain significance Single submitter
- MAP3K6 p.Gln263Arg Uncertain significance Single submitter
- MAP3K6 p.Gln370Arg Uncertain significance Single submitter
- MAP3K6 p.Gln407Lys Uncertain significance Single submitter
- MAP3K6 p.Gln757Arg Uncertain significance Single submitter
- MAP3K6 p.Glu1037Gln Uncertain significance Single submitter
- MAP3K6 p.Glu1126Lys Uncertain significance Single submitter
- MAP3K6 p.Glu542Lys Uncertain significance Single submitter
- MAP3K6 p.Glu585Gln Uncertain significance Single submitter
- MAP3K6 p.Glu63Gly Uncertain significance Single submitter
- MAP3K6 p.Glu63Lys Uncertain significance Single submitter
- MAP3K6 p.Glu647Asp Uncertain significance Single submitter
- MAP3K6 p.Glu66Gln Uncertain significance Single submitter
- MAP3K6 p.Glu66Lys Uncertain significance Single submitter
- MAP3K6 p.Glu77Val Uncertain significance Single submitter
- MAP3K6 p.Glu878Lys Uncertain significance Single submitter
- MAP3K6 p.Glu980Lys Uncertain significance Single submitter
- MAP3K6 p.Gly1064Ala Uncertain significance Single submitter
- MAP3K6 p.Gly1064Arg Uncertain significance Single submitter
- MAP3K6 p.Gly193Asp Uncertain significance Single submitter
- MAP3K6 p.Gly346Asp Uncertain significance Single submitter
- MAP3K6 p.Gly406Trp Uncertain significance Single submitter
- MAP3K6 p.Gly64Val Uncertain significance Single submitter
- MAP3K6 p.Gly657Arg Uncertain significance Single submitter
- MAP3K6 p.Gly739Glu Uncertain significance Single submitter
- MAP3K6 p.Gly853Arg Uncertain significance Single submitter
- MAP3K6 p.Gly97Arg Uncertain significance Single submitter
- MAP3K6 p.His608Gln Uncertain significance Single submitter
- MAP3K6 p.Ile1274Thr Uncertain significance Single submitter
- MAP3K6 p.Ile294Val Uncertain significance Single submitter
- MAP3K6 p.Ile694Phe Uncertain significance Single submitter
- MAP3K6 p.Ile788Asn Uncertain significance Single submitter
- MAP3K6 p.Ile819Thr Uncertain significance Single submitter
- MAP3K6 p.Leu1275Met Uncertain significance Single submitter
- MAP3K6 p.Leu556Pro Uncertain significance Single submitter
- MAP3K6 p.Leu590Arg Uncertain significance Single submitter
- MAP3K6 p.Leu835Arg Uncertain significance Single submitter
- MAP3K6 p.Leu906Pro Uncertain significance Single submitter
- MAP3K6 p.Lys534Glu Uncertain significance Single submitter
- MAP3K6 p.Lys656Arg Uncertain significance Single submitter
- MAP3K6 p.Lys773Thr Uncertain significance Single submitter
- MAP3K6 p.Met1163Ile Uncertain significance Single submitter
- MAP3K6 p.Met363Ile Uncertain significance Single submitter
- MAP3K6 p.Met722Thr Uncertain significance Single submitter
- MAP3K6 p.Met871Ile Uncertain significance Single submitter
- MAP3K6 p.Pro1150Ser Uncertain significance Single submitter
- MAP3K6 p.Pro1161Ser Uncertain significance Single submitter
- MAP3K6 p.Pro1288Leu Uncertain significance Single submitter
- MAP3K6 p.Pro493Ala Uncertain significance Single submitter
- MAP3K6 p.Pro595Gln Uncertain significance Single submitter
- MAP3K6 p.Pro623Leu Uncertain significance Single submitter
- MAP3K6 p.Pro6Ala Uncertain significance Single submitter
- MAP3K6 p.Pro848His Uncertain significance Single submitter
- MAP3K6 p.Pro85Ser Uncertain significance Single submitter
- MAP3K6 p.Pro869Leu Uncertain significance Single submitter
- MAP3K6 p.Pro87Gln Uncertain significance Single submitter
- MAP3K6 p.Pro959Leu Uncertain significance Single submitter
- MAP3K6 p.Ser1149Arg Uncertain significance Single submitter
- MAP3K6 p.Ser121Asn Uncertain significance Single submitter
- MAP3K6 p.Ser1286Cys Uncertain significance Single submitter
- MAP3K6 p.Ser268Asn Uncertain significance Single submitter
- MAP3K6 p.Ser736Leu Uncertain significance Single submitter
- MAP3K6 p.Ser873Asn Uncertain significance Single submitter
- MAP3K6 p.Ser876Leu Uncertain significance Single submitter
- MAP3K6 p.Ser8Ala Uncertain significance Single submitter
- MAP3K6 p.Ser988Arg Uncertain significance Single submitter
- MAP3K6 p.Thr227Ile Uncertain significance Single submitter
- MAP3K6 p.Thr305Pro Uncertain significance Single submitter
- MAP3K6 p.Thr490Lys Uncertain significance Single submitter
- MAP3K6 p.Thr561Ile Uncertain significance Single submitter
- MAP3K6 p.Thr939Ala Uncertain significance Single submitter
- MAP3K6 p.Trp381Arg Uncertain significance Single submitter
- MAP3K6 p.Tyr111His Uncertain significance Single submitter
Predictors split 26
The independent predictors disagree with each other — read with care.
- MAP3K6 p.Ala1111Val Uncertain significance Single submitter
- MAP3K6 p.Ala539Thr Uncertain significance Single submitter
- MAP3K6 p.Arg1001Leu Uncertain significance Single submitter
- MAP3K6 p.Arg1177Cys Uncertain significance Single submitter
- MAP3K6 p.Arg1269Cys Uncertain significance Single submitter
- MAP3K6 p.Arg186Trp Uncertain significance Single submitter
- MAP3K6 p.Arg247Trp Uncertain significance Single submitter
- MAP3K6 p.Arg264Trp Uncertain significance Single submitter
- MAP3K6 p.Arg324Trp Uncertain significance Single submitter
- MAP3K6 p.Arg416Trp Uncertain significance Single submitter
- MAP3K6 p.Arg824Cys Uncertain significance Single submitter
- MAP3K6 p.Glu851Asp Uncertain significance Single submitter
- MAP3K6 p.Leu303Ser Uncertain significance Single submitter
- MAP3K6 p.Leu322Val Uncertain significance Single submitter
- MAP3K6 p.Leu557Pro Uncertain significance Single submitter
- MAP3K6 p.Met355Thr Uncertain significance Single submitter
- MAP3K6 p.Met814Ile Uncertain significance Single submitter
- MAP3K6 p.Phe641Leu Uncertain significance Single submitter
- MAP3K6 p.Pro340Leu Uncertain significance Single submitter
- MAP3K6 p.Pro847Leu Uncertain significance Single submitter
- MAP3K6 p.Ser367Leu Uncertain significance Single submitter
- MAP3K6 p.Ser605Arg Uncertain significance Single submitter
- MAP3K6 p.Ser873Ile Uncertain significance Single submitter
- MAP3K6 p.Thr182Met Uncertain significance Single submitter
- MAP3K6 p.Val432Met Uncertain significance Single submitter
-
MAP3K6 p.Arg668Gly
Benign
No assertion criteria
MAP3K6-related disorder
All MAP3K6 variants
Likely pathogenic 1
- p.Phe849fs Single submitter
Benign 16
- c.2915+9A>T Multiple submitters
- p.Arg499Cys Multiple submitters
- p.Asn622Lys Multiple submitters
- p.Gln1142Arg Multiple submitters
- p.Leu1249= Multiple submitters
- p.Ser929= Multiple submitters
- p.Val207Gly Multiple submitters
- p.Lys1125del Single submitter
- p.Val388Ile Single submitter
- c.2584-6C>T No assertion criteria MAP3K6-related disorder
- c.3259-10C>T No assertion criteria MAP3K6-related disorder
- p.Arg668Gly No assertion criteria MAP3K6-related disorder ⚠
- p.Arg913His No assertion criteria MAP3K6-related disorder
- p.Gly1233Ala No assertion criteria MAP3K6-related disorder
- p.Lys1024Glu No assertion criteria MAP3K6-related disorder
- p.Thr455Ile No assertion criteria MAP3K6-related disorder
Benign/Likely benign 2
- p.Ala405= Multiple submitters
- p.Pro946Leu Multiple submitters
Likely benign 36
- c.1256-2A>G Multiple submitters
- p.Glu248= Multiple submitters
- p.Ser394= Multiple submitters
- c.1256-11C>G Single submitter
- c.1686+19C>A Single submitter
- c.1687-14A>G Single submitter
- c.3081+17A>G Single submitter
- p.Ala246= Single submitter
- p.Ala664= Single submitter
- p.Arg1175= Single submitter
- p.Arg1177His Single submitter
- p.Arg375Gln Single submitter
- p.Arg544Gln Single submitter
- p.Asp200Tyr Single submitter
- p.Asp790= Single submitter
- p.Cys613= Single submitter
- p.Gly1044Arg Single submitter
- p.Ile694= Single submitter
- p.Leu1195= Single submitter
- p.Leu51= Single submitter
- p.Phe515Leu Single submitter
- p.Pro1130Leu Single submitter
- p.Pro489= Single submitter
- p.Pro69= Single submitter
- p.Ser579= Single submitter
- p.Thr184= Single submitter
- p.Thr299= Single submitter
- p.Thr933Ile Single submitter
- p.Thr98= Single submitter
- p.Val1118= Single submitter
- c.1415+9C>T No assertion criteria MAP3K6-related disorder
- c.3711+7C>T No assertion criteria MAP3K6-related disorder
- p.Ala106= No assertion criteria MAP3K6-related disorder
- p.Ala1061Thr No assertion criteria MAP3K6-related disorder
- p.Pro958Thr No assertion criteria MAP3K6-related disorder
- p.Ser917= No assertion criteria MAP3K6-related disorder
Uncertain significance 199
- p.Ala1029Val Single submitter ⚠
- p.Ala1111Val Single submitter ⚠
- p.Ala113Ser Single submitter ⚠
- p.Ala1208Val Single submitter ⚠
- p.Ala151Asp Single submitter ⚠
- p.Ala151Val Single submitter ⚠
- p.Ala246Val Single submitter ⚠
- p.Ala302Asp Single submitter ⚠
- p.Ala332Val Single submitter ⚠
- p.Ala372Thr Single submitter ⚠
- p.Ala40Ser Single submitter ⚠
- p.Ala447Ser Single submitter ⚠
- p.Ala451Val Single submitter ⚠
- p.Ala539Thr Single submitter ⚠
- p.Ala573Ser Single submitter ⚠
- p.Ala695Thr Single submitter ⚠
- p.Ala78Val Single submitter ⚠
- p.Ala897Thr Single submitter ⚠
- p.Ala930Val Single submitter ⚠
- p.Arg1001Leu Single submitter ⚠
- p.Arg1033Gly Single submitter ⚠
- p.Arg1078Ser Single submitter ⚠
- p.Arg1113Gln Single submitter ⚠
- p.Arg1177Cys Single submitter ⚠
- p.Arg1185Gln Single submitter ⚠
- p.Arg1197Gly Single submitter ⚠
- p.Arg1261Cys Single submitter ⚠
- p.Arg1261fs Single submitter
- p.Arg1261His Single submitter ⚠
- p.Arg1269Cys Single submitter ⚠
- p.Arg1269His Single submitter ⚠
- p.Arg1269Pro Single submitter ⚠
- p.Arg1278Gln Single submitter ⚠
- p.Arg186Gln Single submitter ⚠
- p.Arg186Trp Single submitter ⚠
- p.Arg219Gln Single submitter ⚠
- p.Arg219Gly Single submitter ⚠
- p.Arg222Cys Single submitter ⚠
- p.Arg240Trp Single submitter ⚠
- p.Arg241Trp Single submitter ⚠
- p.Arg244Trp Single submitter ⚠
- p.Arg247Trp Single submitter ⚠
- p.Arg256Gln Single submitter ⚠
- p.Arg264Gln Single submitter ⚠
- p.Arg264Trp Single submitter ⚠
- p.Arg27Gln Single submitter ⚠
- p.Arg285His Single submitter ⚠
- p.Arg324Trp Single submitter ⚠
- p.Arg331Gln Single submitter ⚠
- p.Arg331Trp Single submitter ⚠
- p.Arg37Gly Single submitter ⚠
- p.Arg416Trp Single submitter ⚠
- p.Arg488Lys Single submitter ⚠
- p.Arg544Gly Single submitter ⚠
- p.Arg544Trp Single submitter ⚠
- p.Arg586Cys Single submitter ⚠
- p.Arg586His Single submitter
- p.Arg62Pro Single submitter ⚠
- p.Arg73His Single submitter ⚠
- p.Arg753His Single submitter ⚠
- p.Arg796Gly Single submitter ⚠
- p.Arg824Cys Single submitter ⚠
- p.Arg824His Single submitter ⚠
- p.Arg846Cys Single submitter ⚠
- p.Arg86Gln Single submitter ⚠
- p.Arg892His Single submitter ⚠
- p.Arg911Met Single submitter ⚠
- p.Arg913Cys Single submitter ⚠
- p.Arg923Trp Single submitter ⚠
- p.Arg961Ser Single submitter ⚠
- p.Asn143His Single submitter ⚠
- p.Asn397Ser Single submitter ⚠
- p.Asn937Lys Single submitter ⚠
- p.Asp1085Val Single submitter ⚠
- p.Asp1105Glu Single submitter
- p.Asp1140Tyr Single submitter ⚠
- p.Asp1231Gly Single submitter ⚠
- p.Asp1231His Single submitter ⚠
- p.Asp1255Val Single submitter ⚠
- p.Asp152Asn Single submitter ⚠
- p.Asp169Asn Single submitter ⚠
- p.Asp351Asn Single submitter ⚠
- p.Asp523His Single submitter ⚠
- p.Asp743Glu Single submitter ⚠
- p.Cys588Tyr Single submitter ⚠
- p.Gln1010Arg Single submitter ⚠
- p.Gln1025Glu Single submitter ⚠
- p.Gln1095His Single submitter ⚠
- p.Gln1157Arg Single submitter ⚠
- p.Gln1165His Single submitter ⚠
- p.Gln1219Glu Single submitter ⚠
- p.Gln157Arg Single submitter ⚠
- p.Gln263Arg Single submitter ⚠
- p.Gln370Arg Single submitter ⚠
- p.Gln407Lys Single submitter ⚠
- p.Gln757Arg Single submitter ⚠
- p.Gln856Lys Single submitter
- p.Glu1037Gln Single submitter ⚠
- p.Glu1126Lys Single submitter ⚠
- p.Glu542Lys Single submitter ⚠
- p.Glu585Gln Single submitter ⚠
- p.Glu63Gly Single submitter ⚠
- p.Glu63Lys Single submitter ⚠
- p.Glu647Asp Single submitter ⚠
- p.Glu66Gln Single submitter ⚠
- p.Glu66Lys Single submitter ⚠
- p.Glu77Val Single submitter ⚠
- p.Glu851Asp Single submitter ⚠
- p.Glu878Lys Single submitter ⚠
- p.Glu980Lys Single submitter ⚠
- p.Gly1064Ala Single submitter ⚠
- p.Gly1064Arg Single submitter ⚠
- p.Gly1264Arg Single submitter
- p.Gly193Asp Single submitter ⚠
- p.Gly346Asp Single submitter ⚠
- p.Gly406Trp Single submitter ⚠
- p.Gly577Arg Single submitter
- p.Gly64Val Single submitter ⚠
- p.Gly657Arg Single submitter ⚠
- p.Gly739Glu Single submitter ⚠
- p.Gly853Arg Single submitter ⚠
- p.Gly97Arg Single submitter ⚠
- p.His608Gln Single submitter ⚠
- p.Ile1274Thr Single submitter ⚠
- p.Ile294Val Single submitter ⚠
- p.Ile694Phe Single submitter ⚠
- p.Ile788Asn Single submitter ⚠
- p.Ile819Thr Single submitter ⚠
- p.Leu1275Met Single submitter ⚠
- p.Leu303Ser Single submitter ⚠
- p.Leu322Val Single submitter ⚠
- p.Leu556Pro Single submitter ⚠
- p.Leu557Pro Single submitter ⚠
- p.Leu590Arg Single submitter ⚠
- p.Leu835Arg Single submitter ⚠
- p.Leu906Pro Single submitter ⚠
- p.Leu91Pro Single submitter
- p.Lys534Glu Single submitter ⚠
- p.Lys656Arg Single submitter ⚠
- p.Lys773Thr Single submitter ⚠
- p.Met1163Ile Single submitter ⚠
- p.Met355Thr Single submitter ⚠
- p.Met363Ile Single submitter ⚠
- p.Met722Thr Single submitter ⚠
- p.Met814Ile Single submitter ⚠
- p.Met871Ile Single submitter ⚠
- p.Phe641Leu Single submitter ⚠
- p.Pro1150Ser Single submitter ⚠
- p.Pro1161Ser Single submitter ⚠
- p.Pro1288Leu Single submitter ⚠
- p.Pro340Leu Single submitter ⚠
- p.Pro493Ala Single submitter ⚠
- p.Pro595Gln Single submitter ⚠
- p.Pro604Leu Single submitter
- p.Pro623Leu Single submitter ⚠
- p.Pro6Ala Single submitter ⚠
- p.Pro847Leu Single submitter ⚠
- p.Pro847Ser Single submitter
- p.Pro848His Single submitter ⚠
- p.Pro85Ser Single submitter ⚠
- p.Pro869Leu Single submitter ⚠
- p.Pro87Gln Single submitter ⚠
- p.Pro959Leu Single submitter ⚠
- p.Ser1149Arg Single submitter ⚠
- p.Ser121Asn Single submitter ⚠
- p.Ser1286Cys Single submitter ⚠
- p.Ser268Asn Single submitter ⚠
- p.Ser367Leu Single submitter ⚠
- p.Ser605Arg Single submitter ⚠
- p.Ser736Leu Single submitter ⚠
- p.Ser873Asn Single submitter ⚠
- p.Ser873Ile Single submitter ⚠
- p.Ser876Leu Single submitter ⚠
- p.Ser8Ala Single submitter ⚠
- p.Ser988Arg Single submitter ⚠
- p.Thr1260Ile Single submitter
- p.Thr182Met Single submitter ⚠
- p.Thr227Ile Single submitter ⚠
- p.Thr305Pro Single submitter ⚠
- p.Thr490Lys Single submitter ⚠
- p.Thr561Ile Single submitter ⚠
- p.Thr939Ala Single submitter ⚠
- p.Trp381Arg Single submitter ⚠
- p.Tyr111His Single submitter ⚠
- p.Tyr1251Asp Single submitter ⚠
- p.Tyr131His Single submitter ⚠
- p.Tyr643Cys Single submitter ⚠
- p.Tyr826Cys Single submitter ⚠
- p.Tyr965Cys Single submitter ⚠
- p.Tyr965Phe Single submitter ⚠
- p.Val1128Ile Single submitter ⚠
- p.Val115Glu Single submitter ⚠
- p.Val171Ile Single submitter ⚠
- p.Val180Met Single submitter ⚠
- p.Val203Ile Single submitter ⚠
- p.Val432Met Single submitter ⚠
- p.Val50Leu Single submitter ⚠
- p.Val535Met Single submitter ⚠
- p.Val973Met Single submitter ⚠