MAPK8 — 24 ClinVar variants
All ClinVar germline MAPK8 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.
20 Benign · 3 Likely benign · 1 Uncertain significance
Full MAPK8 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactionsAll MAPK8 variants
Benign 20
- c.123-51A>C Multiple submitters
- c.253-80T>A Multiple submitters
- c.311+37A>G Multiple submitters
- c.450+141T>G Multiple submitters
- c.689-56T>A Multiple submitters
- c.997-51T>A Multiple submitters
- c.-49-77C>A Multiple submitters
- c.*154A>G Multiple submitters
- p.Ser393= Multiple submitters
- c.1060+91T>G Single submitter
- c.252+126AT[10] Single submitter
- c.252+126AT[12] Single submitter
- c.252+126AT[13] Single submitter
- c.252+126AT[14] Single submitter
- c.252+141_252+142insGT Single submitter
- c.689-52_689-51insTGTAAATG Single submitter
- c.689-54_689-53insATACATT Single submitter
- c.689-57_689-56insCA Single submitter
- c.871+66G>A Single submitter
- p.Ser97= Single submitter
Likely benign 3
Uncertain significance 1
- p.Trp352Ter Single submitter