MICA — 46 ClinVar variants

All ClinVar germline MICA variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.

1 Conflicting · 5 Benign · 6 Likely benign · 34 Uncertain significance

Full MICA gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

All MICA variants

Conflicting classifications of pathogenicity 1

p.Val302Met Single submitter

Benign 5

p.Ala317fs Single submitter
p.Arg274Gln Single submitter
p.Gly318fs Single submitter
p.Ile236Thr Single submitter
p.Val244Leu Single submitter

Likely benign 6

c.325+1G>A Single submitter
p.Arg213His Single submitter
p.Asn79= Single submitter
p.His184Gln Single submitter
p.Ser228= Single submitter
p.Val199Ile Single submitter

Uncertain significance 34

p.Ala216Val Single submitter
p.Ala22Thr Single submitter
p.Arg213Cys Single submitter
p.Arg240His Single submitter
p.Arg29Cys Single submitter
p.Arg58Cys Single submitter
p.Arg61Ser Single submitter
p.Arg65Gly Single submitter
p.Asp75Tyr Single submitter
p.Cys329Tyr Single submitter
p.Gln106Glu Single submitter
p.Glu48Asp Single submitter
p.Gly254Val Single submitter
p.Gly288Arg Single submitter
p.Gly93Glu Single submitter
p.His184Arg Single submitter
p.Ile116Met Single submitter
p.Leu100Val Single submitter
p.Leu32Phe Single submitter
p.Met163Thr Single submitter
p.Met284Leu Single submitter
p.Pro15Leu Single submitter
p.Pro25Leu Single submitter
p.Pro296Leu Single submitter
p.Ser112Tyr Single submitter
p.Ser126Gly Single submitter
p.Ser217Pro Single submitter
p.Ser27Asn Single submitter
p.Ser291Gly Single submitter
p.Thr266Asn Single submitter
p.Tyr134His Single submitter
p.Val199Ala Single submitter
p.Val223Met Single submitter
p.Val76Asp Single submitter