MT-ND2 — 186 ClinVar variants
All ClinVar germline MT-ND2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more.
1 Likely pathogenic · 52 Benign · 4 Benign/Likely benign · 53 Likely benign · 76 Uncertain significance
Full MT-ND2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactionsAll MT-ND2 variants
Likely pathogenic 1
- m.4810G>A Expert panel mitochondrial disease
Benign 52
- m.4769A>G Expert panel mitochondrial disease
- m.4917A>G Multiple submitters Leigh syndrome
- m.5178C>A Multiple submitters Leigh syndrome
- m.5301A>G Multiple submitters Leigh syndrome
- m.5302T>C Multiple submitters Leigh syndrome
- m.4491G>A Single submitter Leigh syndrome
- m.4501C>T Single submitter Leigh syndrome
- m.4506A>G Single submitter Leigh syndrome
- m.4512G>A Single submitter Leigh syndrome
- m.4560G>A Single submitter Leigh syndrome
- m.4561T>C Single submitter Leigh syndrome
- m.4596G>A Single submitter Leigh syndrome
- m.4615A>G Single submitter Leigh syndrome
- m.4639T>C Single submitter Leigh syndrome
- m.4640C>A Single submitter Leigh syndrome
- m.4659G>A Single submitter Leigh syndrome
- m.4674A>G Single submitter Leigh syndrome
- m.4695T>C Single submitter Leigh syndrome
- m.4696T>C Single submitter Leigh syndrome
- m.4705T>C Single submitter Leigh syndrome
- m.4707C>T Single submitter Leigh syndrome
- m.4722A>G Single submitter Leigh syndrome
- m.4732A>G Single submitter Leigh syndrome
- m.4734A>G Single submitter Leigh syndrome
- m.4735C>A Single submitter Leigh syndrome
- m.4767A>G Single submitter Leigh syndrome
- m.4824A>G Single submitter Leigh syndrome
- m.4833A>G Single submitter Leigh syndrome
- m.4843C>T Single submitter Leigh syndrome
- m.4883C>T Single submitter
- m.4924G>A Single submitter Leigh syndrome
- m.4936C>T Single submitter Leigh syndrome
- m.4965A>G Single submitter Leigh syndrome
- m.5074T>C Single submitter Leigh syndrome
- m.5076C>T Single submitter Leigh syndrome
- m.5147G>A Single submitter
- m.5186A>T Single submitter Leigh syndrome
- m.5194C>T Single submitter Leigh syndrome
- m.5206C>T Single submitter Leigh syndrome
- m.5211C>T Single submitter Leigh syndrome
- m.5262G>A Single submitter Leigh syndrome
- m.5263C>T Single submitter Leigh syndrome
- m.5277T>C Single submitter Leigh syndrome
- m.5319A>G Single submitter Leigh syndrome
- m.5331C>A Single submitter Leigh syndrome
- m.5437C>T Single submitter Leigh syndrome
- m.5442T>C Single submitter Leigh syndrome
- m.5463C>T Single submitter Leigh syndrome
- m.5465T>C Single submitter
- m.5466A>G Single submitter Leigh syndrome
- m.5493T>C Single submitter Leigh syndrome
- m.5495T>C Single submitter
Benign/Likely benign 4
Likely benign 53
- m.5293G>A Expert panel mitochondrial disease
- m.4500T>C Single submitter Leigh syndrome
- m.4529A>T Single submitter
- m.4531C>T Single submitter Leigh syndrome
- m.4612T>C Single submitter Leigh syndrome
- m.4646T>C Single submitter
- m.4654C>T Single submitter Leigh syndrome
- m.4655G>A Single submitter
- m.4688T>C Single submitter
- m.4689A>G Single submitter Leigh syndrome
- m.4702A>G Single submitter Leigh syndrome
- m.4725A>C Single submitter Leigh syndrome
- m.4725A>T Single submitter Leigh syndrome
- m.4728A>G Single submitter Leigh syndrome
- m.4733T>C Single submitter
- m.4745A>G Single submitter
- m.4762T>C Single submitter Leigh syndrome
- m.4763C>A Single submitter Leigh syndrome
- m.4793A>G Single submitter
- m.4812G>A Single submitter Leigh syndrome
- m.4812G>C Single submitter Leigh syndrome
- m.4823T>C Single submitter
- m.4842A>G Single submitter Leigh syndrome
- m.4908C>T Single submitter Leigh syndrome
- m.4911T>G Single submitter Leigh syndrome
- m.4924G>C Single submitter Leigh syndrome
- m.4944A>G Single submitter Leigh syndrome
- m.5033A>G Single submitter
- m.5067A>G Single submitter Leigh syndrome
- m.5069A>T Single submitter Leigh syndrome
- m.5073A>G Single submitter Leigh syndrome
- m.5086C>T Single submitter Leigh syndrome
- m.5095T>C Single submitter Leigh syndrome
- m.5127A>G Single submitter Leigh syndrome
- m.5128A>G Single submitter Leigh syndrome
- m.5149C>T Single submitter Leigh syndrome
- m.5166A>G Single submitter Leigh syndrome
- m.5177G>A Single submitter
- m.5191C>T Single submitter Leigh syndrome
- m.5205T>C Single submitter Leigh syndrome
- m.5252G>A Single submitter
- m.5268A>G Single submitter Leigh syndrome
- m.5273A>T Single submitter Leigh syndrome
- m.5295C>T Single submitter Leigh syndrome
- m.5298A>G Single submitter Leigh syndrome
- m.5316G>A Single submitter Leigh syndrome
- m.5319A>T Single submitter Leigh syndrome
- m.5320C>T Single submitter Leigh syndrome
- m.5325A>T Single submitter Leigh syndrome
- m.5331C>G Single submitter Leigh syndrome
- m.5452C>T Single submitter Leigh syndrome
- m.5484A>G Single submitter Leigh syndrome
- m.5494T>G Single submitter Leigh syndrome
Uncertain significance 76
- m.4611del Expert panel mitochondrial disease
- m.4681T>C Expert panel mitochondrial disease
- m.4735C>G Expert panel mitochondrial disease
- m.4983C>T Expert panel mitochondrial disease
- m.5001dup Expert panel mitochondrial disease
- m.5133_5134del Expert panel mitochondrial disease
- m.5244G>A Expert panel mitochondrial disease
- m.5367_5385del Expert panel mitochondrial disease
- m.4472T>C Single submitter
- m.4480T>C Single submitter Leigh syndrome
- m.4482G>A Single submitter Leigh syndrome
- m.4488C>T Single submitter Leigh syndrome
- m.4494A>G Single submitter Leigh syndrome
- m.4495T>C Single submitter Leigh syndrome
- m.4497T>C Single submitter Leigh syndrome
- m.4503A>T Single submitter Leigh syndrome
- m.4509T>C Single submitter Leigh syndrome
- m.4513C>T Single submitter Leigh syndrome
- m.4548T>C Single submitter Leigh syndrome
- m.4554A>G Single submitter Leigh syndrome
- m.4579T>C Single submitter Leigh syndrome
- m.4597T>C Single submitter
- m.4632G>A Single submitter Leigh syndrome
- m.4638A>G Single submitter Leigh syndrome
- m.4659G>T Single submitter Leigh syndrome
- m.4665G>A Single submitter Leigh syndrome
- m.4676C>A Single submitter Leigh syndrome
- m.4680C>A Single submitter Leigh syndrome
- m.4690T>C Single submitter Leigh syndrome
- m.4717A>T Single submitter Leigh syndrome
- m.4745A>T Single submitter Leigh syndrome
- m.4746T>C Single submitter Leigh syndrome
- m.4749T>C Single submitter Leigh syndrome
- m.4759T>C Single submitter Leigh syndrome
- m.4764A>G Single submitter Leigh syndrome
- m.4765T>C Single submitter Leigh syndrome
- m.4768_4769delinsCG Single submitter Leigh syndrome
- m.4768T>C Single submitter
- m.4770G>A Single submitter Leigh syndrome
- m.4776G>A Single submitter Leigh syndrome
- m.4788G>A Single submitter Leigh syndrome
- m.4789G>A Single submitter Leigh syndrome
- m.4894T>C Single submitter Leigh syndrome
- m.4902A>G Single submitter Leigh syndrome
- m.4923A>T Single submitter Leigh syndrome
- m.4929C>A Single submitter
- m.4929C>T Single submitter Leigh syndrome
- m.4935A>C Single submitter Leigh syndrome
- m.4935A>G Single submitter Leigh syndrome
- m.4948T>C Single submitter Leigh syndrome
- m.4953A>G Single submitter Leigh syndrome
- m.4954T>C Single submitter Leigh syndrome
- m.4974G>A Single submitter Leigh syndrome
- m.5001A>G Single submitter congenital heart disease
- m.5010T>C Single submitter Leigh syndrome
- m.5038T>C Single submitter Leigh syndrome
- m.5047T>C Single submitter Leigh syndrome
- m.5080A>G Single submitter Leigh syndrome
- m.5094A>G Single submitter Leigh syndrome
- m.5105T>C Single submitter
- m.5190A>G Single submitter Leigh syndrome
- m.5265A>G Single submitter Leigh syndrome
- m.5266T>C Single submitter Leigh syndrome
- m.5289A>G Single submitter Leigh syndrome
- m.5295C>A Single submitter Leigh syndrome
- m.5296T>C Single submitter Leigh syndrome
- m.5301A>C Single submitter Leigh syndrome
- m.5310A>G Single submitter Leigh syndrome
- m.5311T>C Single submitter Leigh syndrome
- m.5320C>G Single submitter Leigh syndrome
- m.5325A>G Single submitter Leigh syndrome
- m.5444C>A Single submitter Leigh syndrome
- m.5451A>G Single submitter Leigh syndrome
- m.5496A>G Single submitter Leigh syndrome
- m.5505A>G Single submitter Leigh syndrome
- m.4664C>T No assertion criteria epilepsy