Sugi Variant

Sugi Variant/MYCBP2

MYCBP2 — 774 ClinVar variants

All ClinVar germline MYCBP2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 358 flagged for review →

9 Pathogenic · 7 Likely pathogenic · 3 Conflicting · 31 Benign · 1 Benign/Likely benign · 59 Likely benign · 664 Uncertain significance

Full MYCBP2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 358

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 1

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 297

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 297

Predictors split 60

The independent predictors disagree with each other — read with care.

All MYCBP2 variants

Pathogenic 9

Likely pathogenic 7

Conflicting classifications of pathogenicity 3

Benign 31

Benign/Likely benign 1

Likely benign 59

Uncertain significance 664

Showing the top 300 by review status; the full set is in the sitemap.