Sugi Variant

Sugi Variant/NCOR2

NCOR2 — 590 ClinVar variants

All ClinVar germline NCOR2 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 438 flagged for review →

1 Likely pathogenic · 43 Benign · 80 Likely benign · 466 Uncertain significance

Full NCOR2 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 438

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors vs ClinVar 1

ClinVar calls these pathogenic, but the computational predictors lean tolerated — the highest-value review flag.

Predictors lean, ClinVar uncertain 358

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 358

Predictors split 79

The independent predictors disagree with each other — read with care.

All NCOR2 variants

Likely pathogenic 1

Benign 43

Likely benign 80

Uncertain significance 466

Showing the top 300 by review status; the full set is in the sitemap.