Sugi Variant

Sugi Variant/NIN

NIN — 966 ClinVar variants

All ClinVar germline NIN variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 537 flagged for review →

2 Pathogenic · 3 Likely pathogenic · 26 Conflicting · 93 Benign · 8 Benign/Likely benign · 246 Likely benign · 588 Uncertain significance

Full NIN gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 537

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors agree, ClinVar conflicts 20

ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.

Predictors lean, ClinVar uncertain 456

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 456

Predictors split 61

The independent predictors disagree with each other — read with care.

All NIN variants

Pathogenic 2

Likely pathogenic 3

Conflicting classifications of pathogenicity 26

Benign 93

Benign/Likely benign 8

Likely benign 246

Uncertain significance 588

Showing the top 300 by review status; the full set is in the sitemap.