NRP1 — 298 ClinVar variants
All ClinVar germline NRP1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 164 flagged for review →
15 Benign · 1 Benign/Likely benign · 99 Likely benign · 183 Uncertain significance
Full NRP1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 164
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors lean, ClinVar uncertain 106
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.
- NRP1 p.Ala13Ser Uncertain significance Single submitter
-
NRP1 p.Ala17Ser
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Ala476Val Uncertain significance Single submitter
-
NRP1 p.Ala537Thr
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Arg226His Uncertain significance Single submitter
-
NRP1 p.Arg405Gln
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Arg463Cys Uncertain significance Single submitter
- NRP1 p.Arg535Pro Uncertain significance Single submitter
- NRP1 p.Arg552Trp Uncertain significance Single submitter
- NRP1 p.Arg707Leu Uncertain significance Single submitter
- NRP1 p.Arg767Cys Uncertain significance Single submitter
- NRP1 p.Arg80Lys Uncertain significance Single submitter
- NRP1 p.Asn482Ser Uncertain significance Single submitter
- NRP1 p.Asn609Ser Uncertain significance Single submitter
- NRP1 p.Asn70Ser Uncertain significance Single submitter
- NRP1 p.Asn819Asp Uncertain significance Single submitter
- NRP1 p.Asp825His Uncertain significance Single submitter
- NRP1 p.Asp840Asn Uncertain significance Single submitter
- NRP1 p.Cys661Arg Uncertain significance Single submitter
- NRP1 p.Gln65Arg Uncertain significance Single submitter
-
NRP1 p.Glu312Asp
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Glu826Lys Uncertain significance Single submitter
- NRP1 p.Glu834Asp Uncertain significance Single submitter
-
NRP1 p.Gly202Ala
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Gly203Ala Uncertain significance Single submitter
- NRP1 p.Gly423Ala Uncertain significance Single submitter
- NRP1 p.Gly597Arg Uncertain significance Single submitter
- NRP1 p.His657Leu Uncertain significance Single submitter
- NRP1 p.His732Arg Uncertain significance Single submitter
- NRP1 p.Ile286Ser Uncertain significance Single submitter
-
NRP1 p.Ile31Thr
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Ile372Val Uncertain significance Single submitter
- NRP1 p.Ile442Phe Uncertain significance Single submitter
- NRP1 p.Ile494Phe Uncertain significance Single submitter
- NRP1 p.Ile517Val Uncertain significance Single submitter
- NRP1 p.Ile562Leu Uncertain significance Single submitter
- NRP1 p.Ile635Val Uncertain significance Single submitter
- NRP1 p.Ile824Thr Uncertain significance Single submitter
-
NRP1 p.Lys122Thr
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Lys841Arg Uncertain significance Single submitter
- NRP1 p.Met245Val Uncertain significance Single submitter
- NRP1 p.Met754Ile Uncertain significance Single submitter
- NRP1 p.Phe643Val Uncertain significance Single submitter
- NRP1 p.Phe99Tyr Uncertain significance Single submitter
-
NRP1 p.Pro201Leu
Uncertain significance
Single submitter
NRP1-related disorder
-
NRP1 p.Pro222Ser
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Pro222Thr Uncertain significance Single submitter
- NRP1 p.Pro477Thr Uncertain significance Single submitter
- NRP1 p.Pro632Ser Uncertain significance Single submitter
- NRP1 p.Pro820Thr Uncertain significance Single submitter
- NRP1 p.Pro847Ala Uncertain significance Single submitter
- NRP1 p.Ser637Arg Uncertain significance Single submitter
- NRP1 p.Ser715Ala Uncertain significance Single submitter
- NRP1 p.Ser921Leu Uncertain significance Single submitter
- NRP1 p.Thr30Ala Uncertain significance Single submitter
- NRP1 p.Thr413Ala Uncertain significance Single submitter
- NRP1 p.Tyr694Phe Uncertain significance Single submitter
- NRP1 p.Val328Ala Uncertain significance Single submitter
- NRP1 p.Val438Leu Uncertain significance Single submitter
- NRP1 p.Val585Ala Uncertain significance Single submitter
- NRP1 p.Val600Ala Uncertain significance Single submitter
- NRP1 p.Val712Ala Uncertain significance Single submitter
- NRP1 p.Val874Leu Uncertain significance Single submitter
- NRP1 p.Val878Met Uncertain significance Single submitter
-
NRP1 p.Ala10Val
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ala19Thr
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ala587Val
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg137Cys
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg207His
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg210Gln
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg307Leu
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg334His
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg3Thr
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg741His
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg767His
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Asp636Asn
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gln230Arg
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gln607Glu
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Glu319Gln
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Glu651Ala
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gly453Arg
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gly502Ser
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gly832Ala
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile136Val
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile487Val
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile756Thr
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile859Leu
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Leu119Pro
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Lys702Asn
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Met276Leu
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Met68Ile
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Met68Val
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Pro477Ser
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Pro820Ser
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ser363Arg
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ser731Phe
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr299Ile
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr357Asn
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr388Ser
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr553Ile
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr633Met
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr680Met
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Trp673Gly
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Tyr208His
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Val495Leu
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Val87Met
Uncertain significance
No assertion criteria
NRP1-related disorder
Predictors split 58
The independent predictors disagree with each other — read with care.
- NRP1 p.Ala252Val Uncertain significance Single submitter
- NRP1 p.Ala344Thr Uncertain significance Single submitter
- NRP1 p.Ala882Asp Uncertain significance Single submitter
- NRP1 p.Arg137His Uncertain significance Single submitter
-
NRP1 p.Arg305His
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Arg402Gln Uncertain significance Single submitter
- NRP1 p.Arg468His Uncertain significance Single submitter
- NRP1 p.Asn482Tyr Uncertain significance Single submitter
- NRP1 p.Asn915Lys Uncertain significance Single submitter
- NRP1 p.Asp76Gly Uncertain significance Single submitter
- NRP1 p.Asp79His Uncertain significance Single submitter
- NRP1 p.Glu897Gln Uncertain significance Single submitter
- NRP1 p.Gly490Glu Uncertain significance Single submitter
- NRP1 p.Gly518Arg Uncertain significance Single submitter
- NRP1 p.Gly523Ser Uncertain significance Single submitter
- NRP1 p.Gly573Arg Uncertain significance Single submitter
- NRP1 p.Gly766Glu Uncertain significance Single submitter
- NRP1 p.His571Leu Uncertain significance Single submitter
- NRP1 p.His74Leu Uncertain significance Single submitter
- NRP1 p.His885Pro Uncertain significance Single submitter
- NRP1 p.Lys347Asn Uncertain significance Single submitter
- NRP1 p.Lys359Met Uncertain significance Single submitter
- NRP1 p.Lys846Met Uncertain significance Single submitter
- NRP1 p.Phe511Leu Uncertain significance Single submitter
- NRP1 p.Phe618Leu Uncertain significance Single submitter
- NRP1 p.Pro459Thr Uncertain significance Single submitter
- NRP1 p.Pro856Thr Uncertain significance Single submitter
- NRP1 p.Ser263Gly Uncertain significance Single submitter
- NRP1 p.Ser439Ala Uncertain significance Single submitter
- NRP1 p.Ser695Tyr Uncertain significance Single submitter
- NRP1 p.Ser773Pro Uncertain significance Single submitter
- NRP1 p.Thr337Ala Uncertain significance Single submitter
-
NRP1 p.Thr337Met
Uncertain significance
Single submitter
NRP1-related disorder
- NRP1 p.Thr448Ala Uncertain significance Single submitter
- NRP1 p.Thr448Ile Uncertain significance Single submitter
- NRP1 p.Tyr546Phe Uncertain significance Single submitter
- NRP1 p.Tyr899Cys Uncertain significance Single submitter
- NRP1 p.Val495Met Uncertain significance Single submitter
- NRP1 p.Val705Ala Uncertain significance Single submitter
- NRP1 p.Val705Glu Uncertain significance Single submitter
-
NRP1 p.Arg137Gly
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg334Cys
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg334Ser
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg455Ser
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Arg506Gln
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Asp91Asn
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Cys603Trp
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gly366Arg
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Gly503Trp
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile370Thr
Likely benign
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile487Met
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ile857Met
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Lys83Asn
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Pro592Leu
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ser432Phe
Likely benign
No assertion criteria
NRP1-related disorder
-
NRP1 p.Ser520Thr
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Thr559Met
Uncertain significance
No assertion criteria
NRP1-related disorder
-
NRP1 p.Tyr310His
Uncertain significance
No assertion criteria
NRP1-related disorder
All NRP1 variants
Benign 15
- p.Asp81= Multiple submitters
- p.Ser267Asn Multiple submitters
- p.Ser524Leu Multiple submitters
- p.Leu489= Single submitter
- p.Gly20= No assertion criteria NRP1-related disorder
- p.Leu580= No assertion criteria NRP1-related disorder
- p.Phe561Leu No assertion criteria NRP1-related disorder
- p.Phe781= No assertion criteria NRP1-related disorder
- p.Pro387= No assertion criteria NRP1-related disorder
- p.Ser865= No assertion criteria NRP1-related disorder
- p.Thr249= No assertion criteria NRP1-related disorder
- p.Thr830= No assertion criteria NRP1-related disorder
- p.Tyr422= No assertion criteria NRP1-related disorder
- p.Val733Ile No assertion criteria NRP1-related disorder
- p.Val877= No assertion criteria NRP1-related disorder
Benign/Likely benign 1
- p.Glu834Lys Multiple submitters
Likely benign 99
- c.1759+1317G>A Single submitter
- c.1864+138C>T Single submitter
- c.1864+53T>C Single submitter
- c.2431+3A>G Single submitter
- c.2483-3T>C Single submitter
- p.Asn522= Single submitter
- p.Gly20Ser Single submitter
- p.Ile140Leu Single submitter
- p.Ile498Val Single submitter
- p.Pro110Ser Single submitter
- p.Val15Ala Single submitter
- p.Val269Ile Single submitter
- c.1864+10C>T No assertion criteria NRP1-related disorder
- c.1865-8T>A No assertion criteria NRP1-related disorder
- c.1925-5T>C No assertion criteria NRP1-related disorder
- c.2062+5C>T No assertion criteria NRP1-related disorder
- c.2062+9G>A No assertion criteria NRP1-related disorder
- c.2432-4T>A No assertion criteria NRP1-related disorder
- c.2432-5G>A No assertion criteria NRP1-related disorder
- c.2482+9G>T No assertion criteria NRP1-related disorder
- c.2483-7del No assertion criteria NRP1-related disorder
- c.2483-7dup No assertion criteria NRP1-related disorder
- c.249-6T>C No assertion criteria NRP1-related disorder
- c.249-9G>C No assertion criteria NRP1-related disorder
- c.658+6A>T No assertion criteria NRP1-related disorder
- c.74-4G>C No assertion criteria NRP1-related disorder
- c.814+8T>C No assertion criteria NRP1-related disorder
- c.815-5T>C No assertion criteria NRP1-related disorder
- c.981+5G>A No assertion criteria NRP1-related disorder
- c.982-3C>T No assertion criteria NRP1-related disorder
- c.*5A>T No assertion criteria NRP1-related disorder
- c.*6G>A No assertion criteria NRP1-related disorder
- c.*7A>G No assertion criteria NRP1-related disorder
- p.Ala10= No assertion criteria NRP1-related disorder
- p.Ala537= No assertion criteria NRP1-related disorder
- p.Arg100= No assertion criteria NRP1-related disorder
- p.Arg568= No assertion criteria NRP1-related disorder
- p.Asn24= No assertion criteria NRP1-related disorder
- p.Asn365= No assertion criteria NRP1-related disorder
- p.Asn596= No assertion criteria NRP1-related disorder
- p.Asp289= No assertion criteria NRP1-related disorder
- p.Asp361= No assertion criteria NRP1-related disorder
- p.Asp444= No assertion criteria NRP1-related disorder
- p.Asp454= No assertion criteria NRP1-related disorder
- p.Asp605= No assertion criteria NRP1-related disorder
- p.Asp796= No assertion criteria NRP1-related disorder
- p.Gln290= No assertion criteria NRP1-related disorder
- p.Gln696= No assertion criteria NRP1-related disorder
- p.Gln806= No assertion criteria NRP1-related disorder
- p.Glu256= No assertion criteria NRP1-related disorder
- p.Glu567= No assertion criteria NRP1-related disorder
- p.Gly133= No assertion criteria NRP1-related disorder
- p.Gly229= No assertion criteria NRP1-related disorder
- p.Gly241= No assertion criteria NRP1-related disorder
- p.Gly28= No assertion criteria NRP1-related disorder
- p.Gly343= No assertion criteria NRP1-related disorder
- p.Gly597= No assertion criteria NRP1-related disorder
- p.Gly783= No assertion criteria NRP1-related disorder
- p.Gly786= No assertion criteria NRP1-related disorder
- p.Gly837= No assertion criteria NRP1-related disorder
- p.Gly97= No assertion criteria NRP1-related disorder
- p.His665= No assertion criteria NRP1-related disorder
- p.His668= No assertion criteria NRP1-related disorder
- p.Ile360= No assertion criteria NRP1-related disorder
- p.Ile370Thr No assertion criteria NRP1-related disorder ⚠
- p.Ile494= No assertion criteria NRP1-related disorder
- p.Ile499= No assertion criteria NRP1-related disorder
- p.Ile517= No assertion criteria NRP1-related disorder
- p.Ile785= No assertion criteria NRP1-related disorder
- p.Leu279= No assertion criteria NRP1-related disorder
- p.Leu435= No assertion criteria NRP1-related disorder
- p.Leu574Val No assertion criteria NRP1-related disorder
- p.Leu599= No assertion criteria NRP1-related disorder
- p.Leu854= No assertion criteria NRP1-related disorder
- p.Leu896= No assertion criteria NRP1-related disorder
- p.Leu914= No assertion criteria NRP1-related disorder
- p.Phe205= No assertion criteria NRP1-related disorder
- p.Phe692= No assertion criteria NRP1-related disorder
- p.Pro475= No assertion criteria NRP1-related disorder
- p.Pro592= No assertion criteria NRP1-related disorder
- p.Pro682= No assertion criteria NRP1-related disorder
- p.Ser240= No assertion criteria NRP1-related disorder
- p.Ser251= No assertion criteria NRP1-related disorder
- p.Ser432Phe No assertion criteria NRP1-related disorder ⚠
- p.Ser520Gly No assertion criteria NRP1-related disorder
- p.Ser524= No assertion criteria NRP1-related disorder
- p.Ser921= No assertion criteria NRP1-related disorder
- p.Thr337= No assertion criteria NRP1-related disorder
- p.Thr680= No assertion criteria NRP1-related disorder
- p.Thr916= No assertion criteria NRP1-related disorder
- p.Tyr127= No assertion criteria NRP1-related disorder
- p.Tyr354= No assertion criteria NRP1-related disorder
- p.Tyr646= No assertion criteria NRP1-related disorder
- p.Tyr833= No assertion criteria NRP1-related disorder
- p.Tyr86= No assertion criteria NRP1-related disorder
- p.Val421= No assertion criteria NRP1-related disorder
- p.Val510= No assertion criteria NRP1-related disorder
- p.Val600= No assertion criteria NRP1-related disorder
- p.Val779= No assertion criteria NRP1-related disorder
Uncertain significance 183
- p.Ala13Ser Single submitter ⚠
- p.Ala17Ser Single submitter NRP1-related disorder ⚠
- p.Ala252Val Single submitter ⚠
- p.Ala344Thr Single submitter ⚠
- p.Ala476Val Single submitter ⚠
- p.Ala537Thr Single submitter NRP1-related disorder ⚠
- p.Ala882Asp Single submitter ⚠
- p.Arg137His Single submitter ⚠
- p.Arg226His Single submitter ⚠
- p.Arg305His Single submitter NRP1-related disorder ⚠
- p.Arg402Gln Single submitter ⚠
- p.Arg405Gln Single submitter NRP1-related disorder ⚠
- p.Arg463Cys Single submitter ⚠
- p.Arg468His Single submitter ⚠
- p.Arg535Pro Single submitter ⚠
- p.Arg552Trp Single submitter ⚠
- p.Arg707Leu Single submitter ⚠
- p.Arg767Cys Single submitter ⚠
- p.Arg80Lys Single submitter ⚠
- p.Asn482Ser Single submitter ⚠
- p.Asn482Tyr Single submitter ⚠
- p.Asn609Ser Single submitter ⚠
- p.Asn70Ser Single submitter ⚠
- p.Asn819Asp Single submitter ⚠
- p.Asn915Lys Single submitter ⚠
- p.Asp636fs Single submitter
- p.Asp76Gly Single submitter ⚠
- p.Asp79His Single submitter ⚠
- p.Asp825His Single submitter ⚠
- p.Asp840Asn Single submitter ⚠
- p.Cys661Arg Single submitter ⚠
- p.Gln65Arg Single submitter ⚠
- p.Glu312Asp Single submitter NRP1-related disorder ⚠
- p.Glu826Lys Single submitter ⚠
- p.Glu834Asp Single submitter ⚠
- p.Glu897Gln Single submitter ⚠
- p.Gly202Ala Single submitter NRP1-related disorder ⚠
- p.Gly203Ala Single submitter ⚠
- p.Gly423Ala Single submitter ⚠
- p.Gly43Ser Single submitter NRP1-related disorder
- p.Gly490Glu Single submitter ⚠
- p.Gly518Arg Single submitter ⚠
- p.Gly523Ser Single submitter ⚠
- p.Gly542= Single submitter NRP1-related disorder
- p.Gly573Arg Single submitter ⚠
- p.Gly597Arg Single submitter ⚠
- p.Gly766Glu Single submitter ⚠
- p.His571Leu Single submitter ⚠
- p.His657Leu Single submitter ⚠
- p.His732Arg Single submitter ⚠
- p.His732Gln Single submitter
- p.His74Leu Single submitter ⚠
- p.His885Pro Single submitter ⚠
- p.Ile286Ser Single submitter ⚠
- p.Ile31Thr Single submitter NRP1-related disorder ⚠
- p.Ile372Val Single submitter ⚠
- p.Ile442Phe Single submitter ⚠
- p.Ile494Phe Single submitter ⚠
- p.Ile517Val Single submitter ⚠
- p.Ile562Leu Single submitter ⚠
- p.Ile635Val Single submitter ⚠
- p.Ile824Thr Single submitter ⚠
- p.Lys122Thr Single submitter NRP1-related disorder ⚠
- p.Lys347Asn Single submitter ⚠
- p.Lys359Met Single submitter ⚠
- p.Lys841Arg Single submitter ⚠
- p.Lys846Met Single submitter ⚠
- p.Met245Val Single submitter ⚠
- p.Met68Thr Single submitter
- p.Met754Ile Single submitter ⚠
- p.Phe511Leu Single submitter ⚠
- p.Phe618Leu Single submitter ⚠
- p.Phe643Val Single submitter ⚠
- p.Phe99Tyr Single submitter ⚠
- p.Pro201Leu Single submitter NRP1-related disorder ⚠
- p.Pro222Ser Single submitter NRP1-related disorder ⚠
- p.Pro222Thr Single submitter ⚠
- p.Pro378Arg Single submitter
- p.Pro459Thr Single submitter ⚠
- p.Pro477Thr Single submitter ⚠
- p.Pro632Ser Single submitter ⚠
- p.Pro820Thr Single submitter ⚠
- p.Pro847Ala Single submitter ⚠
- p.Pro856Thr Single submitter ⚠
- p.Ser263Gly Single submitter ⚠
- p.Ser439Ala Single submitter ⚠
- p.Ser637Arg Single submitter ⚠
- p.Ser695Tyr Single submitter ⚠
- p.Ser715Ala Single submitter ⚠
- p.Ser773Pro Single submitter ⚠
- p.Ser921Leu Single submitter ⚠
- p.Thr30Ala Single submitter ⚠
- p.Thr337Ala Single submitter ⚠
- p.Thr337Met Single submitter NRP1-related disorder ⚠
- p.Thr40Ile Single submitter
- p.Thr413Ala Single submitter ⚠
- p.Thr448Ala Single submitter ⚠
- p.Thr448Ile Single submitter ⚠
- p.Tyr546Phe Single submitter ⚠
- p.Tyr694Phe Single submitter ⚠
- p.Tyr899Cys Single submitter ⚠
- p.Val328Ala Single submitter ⚠
- p.Val438Leu Single submitter ⚠
- p.Val495Met Single submitter ⚠
- p.Val585Ala Single submitter ⚠
- p.Val600Ala Single submitter ⚠
- p.Val705Ala Single submitter ⚠
- p.Val705Glu Single submitter ⚠
- p.Val712Ala Single submitter ⚠
- p.Val779Leu Single submitter
- p.Val850Leu Single submitter
- p.Val874Leu Single submitter ⚠
- p.Val877Phe Single submitter
- p.Val878Met Single submitter ⚠
- c.1283-5C>A No assertion criteria NRP1-related disorder
- c.1865-1G>T No assertion criteria NRP1-related disorder
- c.1924+6A>G No assertion criteria NRP1-related disorder
- c.1925-3A>C No assertion criteria NRP1-related disorder
- c.248+2T>G No assertion criteria
- c.248+3_248+6del No assertion criteria NRP1-related disorder
- c.73+5G>A No assertion criteria NRP1-related disorder
- p.Ala10Val No assertion criteria NRP1-related disorder ⚠
- p.Ala19Thr No assertion criteria NRP1-related disorder ⚠
- p.Ala587Val No assertion criteria NRP1-related disorder ⚠
- p.Arg137Cys No assertion criteria NRP1-related disorder ⚠
- p.Arg137Gly No assertion criteria NRP1-related disorder ⚠
- p.Arg207His No assertion criteria NRP1-related disorder ⚠
- p.Arg210Gln No assertion criteria NRP1-related disorder ⚠
- p.Arg307Leu No assertion criteria NRP1-related disorder ⚠
- p.Arg334Cys No assertion criteria NRP1-related disorder ⚠
- p.Arg334His No assertion criteria NRP1-related disorder ⚠
- p.Arg334Ser No assertion criteria NRP1-related disorder ⚠
- p.Arg3Thr No assertion criteria NRP1-related disorder ⚠
- p.Arg455Ser No assertion criteria NRP1-related disorder ⚠
- p.Arg506Gln No assertion criteria NRP1-related disorder ⚠
- p.Arg741His No assertion criteria NRP1-related disorder ⚠
- p.Arg767His No assertion criteria NRP1-related disorder ⚠
- p.Asn545del No assertion criteria NRP1-related disorder
- p.Asp636Asn No assertion criteria NRP1-related disorder ⚠
- p.Asp91Asn No assertion criteria NRP1-related disorder ⚠
- p.Cys603Trp No assertion criteria NRP1-related disorder ⚠
- p.Gln230Arg No assertion criteria NRP1-related disorder ⚠
- p.Gln607Glu No assertion criteria NRP1-related disorder ⚠
- p.Glu319Gln No assertion criteria NRP1-related disorder ⚠
- p.Glu541Gln No assertion criteria NRP1-related disorder
- p.Glu651Ala No assertion criteria NRP1-related disorder ⚠
- p.Gly366Arg No assertion criteria NRP1-related disorder ⚠
- p.Gly453Arg No assertion criteria NRP1-related disorder ⚠
- p.Gly502Ser No assertion criteria NRP1-related disorder ⚠
- p.Gly503Trp No assertion criteria NRP1-related disorder ⚠
- p.Gly832Ala No assertion criteria NRP1-related disorder ⚠
- p.Ile136Val No assertion criteria NRP1-related disorder ⚠
- p.Ile487Met No assertion criteria NRP1-related disorder ⚠
- p.Ile487Val No assertion criteria NRP1-related disorder ⚠
- p.Ile756Thr No assertion criteria NRP1-related disorder ⚠
- p.Ile857Met No assertion criteria NRP1-related disorder ⚠
- p.Ile859Leu No assertion criteria NRP1-related disorder ⚠
- p.Leu119Pro No assertion criteria NRP1-related disorder ⚠
- p.Lys702Asn No assertion criteria NRP1-related disorder ⚠
- p.Lys83Asn No assertion criteria NRP1-related disorder ⚠
- p.Met276Leu No assertion criteria NRP1-related disorder ⚠
- p.Met68Ile No assertion criteria NRP1-related disorder ⚠
- p.Met68Val No assertion criteria NRP1-related disorder ⚠
- p.Phe90= No assertion criteria NRP1-related disorder
- p.Pro477Ser No assertion criteria NRP1-related disorder ⚠
- p.Pro592Leu No assertion criteria NRP1-related disorder ⚠
- p.Pro820Ser No assertion criteria NRP1-related disorder ⚠
- p.Ser363Arg No assertion criteria NRP1-related disorder ⚠
- p.Ser520Thr No assertion criteria NRP1-related disorder ⚠
- p.Ser731Phe No assertion criteria NRP1-related disorder ⚠
- p.Ser918Arg No assertion criteria NRP1-related disorder
- p.Thr299Ile No assertion criteria NRP1-related disorder ⚠
- p.Thr357Asn No assertion criteria NRP1-related disorder ⚠
- p.Thr388Ser No assertion criteria NRP1-related disorder ⚠
- p.Thr553Ile No assertion criteria NRP1-related disorder ⚠
- p.Thr559Met No assertion criteria NRP1-related disorder ⚠
- p.Thr633Met No assertion criteria NRP1-related disorder ⚠
- p.Thr680Met No assertion criteria NRP1-related disorder ⚠
- p.Trp673Gly No assertion criteria NRP1-related disorder ⚠
- p.Tyr208His No assertion criteria NRP1-related disorder ⚠
- p.Tyr310His No assertion criteria NRP1-related disorder ⚠
- p.Val495Leu No assertion criteria NRP1-related disorder ⚠
- p.Val87Met No assertion criteria NRP1-related disorder ⚠