Sugi Variant

Sugi Variant/NTF4

NTF4 — 50 ClinVar variants

All ClinVar germline NTF4 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 37 flagged for review →

1 Likely pathogenic · 2 Benign · 7 Likely benign · 40 Uncertain significance

Full NTF4 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions

⚑ Evidence disagreements 37

Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.

Predictors lean, ClinVar uncertain 30

ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification.

Predictors split 7

The independent predictors disagree with each other — read with care.

All NTF4 variants

Likely pathogenic 1

Benign 2

Likely benign 7

Uncertain significance 40