PHRF1 — 412 ClinVar variants
All ClinVar germline PHRF1 variants across every classification, each assembled from ClinVar, gnomAD, AlphaMissense, conservation and more. 338 flagged for review →
1 Conflicting · 4 Benign · 56 Likely benign · 351 Uncertain significance
Full PHRF1 gene report on Sugi Atlas → Gene function, pathways, protein structure, constraint & interactions⚑ Evidence disagreements 338
Variants where the independent computational evidence doesn't line up with the clinical picture — a QC signal for a second look, not a reclassification.
Predictors agree, ClinVar conflicts 1
ClinVar submitters conflict, but the independent predictors unanimously agree — a QC review flag, not a reclassification.
Predictors lean, ClinVar uncertain 315
ClinVar classifies these uncertain (VUS), but the independent predictors unanimously lean one way — a triage signal for review, not a reclassification. · showing the 150 best-reviewed of 315
- PHRF1 p.Ala114Ser Uncertain significance Single submitter
- PHRF1 p.Ala114Val Uncertain significance Single submitter
- PHRF1 p.Ala1197Ser Uncertain significance Single submitter
- PHRF1 p.Ala1249Gly Uncertain significance Single submitter
- PHRF1 p.Ala1278Thr Uncertain significance Single submitter
- PHRF1 p.Ala127Thr Uncertain significance Single submitter
- PHRF1 p.Ala1308Val Uncertain significance Single submitter
- PHRF1 p.Ala1318Thr Uncertain significance Single submitter
- PHRF1 p.Ala1351Pro Uncertain significance Single submitter
- PHRF1 p.Ala1355Val Uncertain significance Single submitter
- PHRF1 p.Ala1364Val Uncertain significance Single submitter
- PHRF1 p.Ala1381Thr Uncertain significance Single submitter
- PHRF1 p.Ala1382Gly Uncertain significance Single submitter
- PHRF1 p.Ala1414Thr Uncertain significance Single submitter
- PHRF1 p.Ala1420Pro Uncertain significance Single submitter
- PHRF1 p.Ala1420Ser Uncertain significance Single submitter
- PHRF1 p.Ala1492Thr Uncertain significance Single submitter
- PHRF1 p.Ala1515Val Uncertain significance Single submitter
- PHRF1 p.Ala1552Thr Uncertain significance Single submitter
- PHRF1 p.Ala1552Val Uncertain significance Single submitter
- PHRF1 p.Ala176Val Uncertain significance Single submitter
- PHRF1 p.Ala232Pro Uncertain significance Single submitter
- PHRF1 p.Ala232Val Uncertain significance Single submitter
- PHRF1 p.Ala239Val Uncertain significance Single submitter
- PHRF1 p.Ala241Val Uncertain significance Single submitter
- PHRF1 p.Ala284Glu Uncertain significance Single submitter
- PHRF1 p.Ala294Thr Uncertain significance Single submitter
- PHRF1 p.Ala317Val Uncertain significance Single submitter
- PHRF1 p.Ala365Val Uncertain significance Single submitter
- PHRF1 p.Ala424Val Uncertain significance Single submitter
- PHRF1 p.Ala570Ser Uncertain significance Single submitter
- PHRF1 p.Ala593Thr Uncertain significance Single submitter
- PHRF1 p.Ala593Val Uncertain significance Single submitter
- PHRF1 p.Ala610Val Uncertain significance Single submitter
- PHRF1 p.Ala646Glu Uncertain significance Single submitter
- PHRF1 p.Ala646Thr Uncertain significance Single submitter
- PHRF1 p.Ala670Thr Uncertain significance Single submitter
- PHRF1 p.Ala752Gly Uncertain significance Single submitter
- PHRF1 p.Ala842Thr Uncertain significance Single submitter
- PHRF1 p.Ala910Thr Uncertain significance Single submitter
- PHRF1 p.Ala930Val Uncertain significance Single submitter
- PHRF1 p.Ala947Val Uncertain significance Single submitter
- PHRF1 p.Ala95Thr Uncertain significance Single submitter
- PHRF1 p.Ala970Gly Uncertain significance Single submitter
- PHRF1 p.Arg1000Cys Uncertain significance Single submitter
- PHRF1 p.Arg1000His Uncertain significance Single submitter
- PHRF1 p.Arg1016Trp Uncertain significance Single submitter
- PHRF1 p.Arg1018Leu Uncertain significance Single submitter
- PHRF1 p.Arg1041Cys Uncertain significance Single submitter
- PHRF1 p.Arg1053Gln Uncertain significance Single submitter
- PHRF1 p.Arg1053Trp Uncertain significance Single submitter
- PHRF1 p.Arg1062Gln Uncertain significance Single submitter
- PHRF1 p.Arg1062Gly Uncertain significance Single submitter
- PHRF1 p.Arg1079Gln Uncertain significance Single submitter
- PHRF1 p.Arg1087Lys Uncertain significance Single submitter
- PHRF1 p.Arg1090Gln Uncertain significance Single submitter
- PHRF1 p.Arg1092Gln Uncertain significance Single submitter
-
PHRF1 p.Arg1092Pro
Uncertain significance
Single submitter
PHRF1-related disorder
- PHRF1 p.Arg1092Trp Uncertain significance Single submitter
- PHRF1 p.Arg1119Gln Uncertain significance Single submitter
- PHRF1 p.Arg1139Trp Uncertain significance Single submitter
- PHRF1 p.Arg1145Gln Uncertain significance Single submitter
- PHRF1 p.Arg1156Gln Uncertain significance Single submitter
- PHRF1 p.Arg1158Gln Uncertain significance Single submitter
- PHRF1 p.Arg1158Trp Uncertain significance Single submitter
- PHRF1 p.Arg1159Lys Uncertain significance Single submitter
- PHRF1 p.Arg1161Gln Uncertain significance Single submitter
- PHRF1 p.Arg1164Trp Uncertain significance Single submitter
- PHRF1 p.Arg1173Trp Uncertain significance Single submitter
- PHRF1 p.Arg1177Leu Uncertain significance Single submitter
- PHRF1 p.Arg1177Trp Uncertain significance Single submitter
- PHRF1 p.Arg1179Gln Uncertain significance Single submitter
- PHRF1 p.Arg1179Trp Uncertain significance Single submitter
- PHRF1 p.Arg1181Cys Uncertain significance Single submitter
- PHRF1 p.Arg1181His Uncertain significance Single submitter
- PHRF1 p.Arg1188Pro Uncertain significance Single submitter
- PHRF1 p.Arg1213Trp Uncertain significance Single submitter
- PHRF1 p.Arg12Gln Uncertain significance Single submitter
- PHRF1 p.Arg12Pro Uncertain significance Single submitter
- PHRF1 p.Arg1301Gln Uncertain significance Single submitter
- PHRF1 p.Arg1377Lys Uncertain significance Single submitter
- PHRF1 p.Arg1383Trp Uncertain significance Single submitter
- PHRF1 p.Arg1419Ile Uncertain significance Single submitter
- PHRF1 p.Arg1419Lys Uncertain significance Single submitter
- PHRF1 p.Arg1549Lys Uncertain significance Single submitter
- PHRF1 p.Arg194His Uncertain significance Single submitter
- PHRF1 p.Arg264Trp Uncertain significance Single submitter
- PHRF1 p.Arg266Gln Uncertain significance Single submitter
- PHRF1 p.Arg277Leu Uncertain significance Single submitter
- PHRF1 p.Arg277Trp Uncertain significance Single submitter
- PHRF1 p.Arg336Gln Uncertain significance Single submitter
- PHRF1 p.Arg337Gln Uncertain significance Single submitter
- PHRF1 p.Arg371His Uncertain significance Single submitter
- PHRF1 p.Arg462Trp Uncertain significance Single submitter
- PHRF1 p.Arg466Trp Uncertain significance Single submitter
- PHRF1 p.Arg487Cys Uncertain significance Single submitter
- PHRF1 p.Arg588Ser Uncertain significance Single submitter
- PHRF1 p.Arg594His Uncertain significance Single submitter
- PHRF1 p.Arg614Gly Uncertain significance Single submitter
- PHRF1 p.Arg673Gly Uncertain significance Single submitter
- PHRF1 p.Arg673Lys Uncertain significance Single submitter
- PHRF1 p.Arg749Gln Uncertain significance Single submitter
- PHRF1 p.Arg749Trp Uncertain significance Single submitter
- PHRF1 p.Arg778Gln Uncertain significance Single submitter
- PHRF1 p.Arg801Gln Uncertain significance Single submitter
- PHRF1 p.Arg801Trp Uncertain significance Single submitter
- PHRF1 p.Arg826Gln Uncertain significance Single submitter
- PHRF1 p.Arg906Trp Uncertain significance Single submitter
- PHRF1 p.Arg958Trp Uncertain significance Single submitter
- PHRF1 p.Arg994His Uncertain significance Single submitter
- PHRF1 p.Asn100Ser Uncertain significance Single submitter
- PHRF1 p.Asn113Ser Uncertain significance Single submitter
- PHRF1 p.Asn289Ile Uncertain significance Single submitter
- PHRF1 p.Asp103Gly Uncertain significance Single submitter
- PHRF1 p.Asp1072Gly Uncertain significance Single submitter
- PHRF1 p.Asp1236Asn Uncertain significance Single submitter
- PHRF1 p.Asp1236Val Uncertain significance Single submitter
- PHRF1 p.Asp1258Asn Uncertain significance Single submitter
- PHRF1 p.Asp1330Glu Uncertain significance Single submitter
- PHRF1 p.Asp1467Glu Uncertain significance Single submitter
- PHRF1 p.Asp310Gly Uncertain significance Single submitter
- PHRF1 p.Asp44Gly Uncertain significance Single submitter
- PHRF1 p.Asp4Asn Uncertain significance Single submitter
- PHRF1 p.Asp55Asn Uncertain significance Single submitter
- PHRF1 p.Asp675Asn Uncertain significance Single submitter
- PHRF1 p.Asp79Asn Uncertain significance Single submitter
- PHRF1 p.Asp804Ala Uncertain significance Single submitter
- PHRF1 p.Asp834Asn Uncertain significance Single submitter
- PHRF1 p.Cys1512Gly Uncertain significance Single submitter
- PHRF1 p.Cys156Tyr Uncertain significance Single submitter
- PHRF1 p.Cys186Tyr Uncertain significance Single submitter
- PHRF1 p.Gln1379Glu Uncertain significance Single submitter
- PHRF1 p.Gln1429Arg Uncertain significance Single submitter
- PHRF1 p.Gln571Arg Uncertain significance Single submitter
- PHRF1 p.Gln612Glu Uncertain significance Single submitter
- PHRF1 p.Gln722Lys Uncertain significance Single submitter
- PHRF1 p.Gln874Pro Uncertain significance Single submitter
- PHRF1 p.Glu1105Lys Uncertain significance Single submitter
- PHRF1 p.Glu1144Lys Uncertain significance Single submitter
- PHRF1 p.Glu1169Val Uncertain significance Single submitter
- PHRF1 p.Glu1210Lys Uncertain significance Single submitter
- PHRF1 p.Glu1225Val Uncertain significance Single submitter
- PHRF1 p.Glu1385Gly Uncertain significance Single submitter
- PHRF1 p.Glu1559Lys Uncertain significance Single submitter
- PHRF1 p.Glu1640Lys Uncertain significance Single submitter
- PHRF1 p.Glu1648Lys Uncertain significance Single submitter
- PHRF1 p.Glu180Gly Uncertain significance Single submitter
- PHRF1 p.Glu229Gln Uncertain significance Single submitter
- PHRF1 p.Glu248Asp Uncertain significance Single submitter
- PHRF1 p.Glu386Ala Uncertain significance Single submitter
Predictors split 22
The independent predictors disagree with each other — read with care.
- PHRF1 p.Arg1046Trp Uncertain significance Single submitter
- PHRF1 p.Arg1631Cys Uncertain significance Single submitter
- PHRF1 p.Arg290Gly Uncertain significance Single submitter
- PHRF1 p.Arg395Trp Uncertain significance Single submitter
- PHRF1 p.Asp182Tyr Uncertain significance Single submitter
- PHRF1 p.Asp504Glu Uncertain significance Single submitter
- PHRF1 p.Glu1293Lys Uncertain significance Single submitter
- PHRF1 p.Glu247Lys Uncertain significance Single submitter
- PHRF1 p.Gly1262Asp Uncertain significance Single submitter
- PHRF1 p.Ile135Val Uncertain significance Single submitter
- PHRF1 p.Ile157Ser Uncertain significance Single submitter
- PHRF1 p.Met1286Ile Uncertain significance Single submitter
- PHRF1 p.Phe130Tyr Uncertain significance Single submitter
- PHRF1 p.Phe161Leu Uncertain significance Single submitter
- PHRF1 p.Pro835Arg Uncertain significance Single submitter
- PHRF1 p.Ser1019Tyr Uncertain significance Single submitter
- PHRF1 p.Ser1608Asn Uncertain significance Single submitter
- PHRF1 p.Ser532Cys Uncertain significance Single submitter
- PHRF1 p.Thr1404Ile Uncertain significance Single submitter
- PHRF1 p.Tyr830Cys Uncertain significance Single submitter
- PHRF1 p.Val1400Leu Uncertain significance Single submitter
- PHRF1 p.Val1587Met Uncertain significance Single submitter
All PHRF1 variants
Conflicting classifications of pathogenicity 1
- p.Ser948Phe Single submitter ⚠
Benign 4
- p.Ala1355= Multiple submitters
- p.Gly1209Arg Multiple submitters
- p.Ser1168Leu Multiple submitters
- p.Gly742Arg No assertion criteria PHRF1-related disorder
Likely benign 56
- p.Ser1457Gly Multiple submitters
- p.Thr959= Multiple submitters
- p.Ala1033Val Single submitter
- p.Ala114Thr Single submitter
- p.Ala1351Val Single submitter
- p.Ala1366Val Single submitter
- p.Ala1523Thr Single submitter
- p.Ala394= Single submitter
- p.Ala646= Single submitter
- p.Ala901Thr Single submitter
- p.Arg1041His Single submitter
- p.Arg303His Single submitter
- p.Arg487His Single submitter
- p.Arg590Cys Single submitter
- p.Arg694Gln Single submitter
- p.Arg739Gln Single submitter
- p.Arg906Gln Single submitter
- p.Arg933Gln Single submitter
- p.Asp1255= Single submitter
- p.Asp1255Glu Single submitter
- p.Asp1350= Single submitter
- p.Glu1356Ala Single submitter
- p.Gly1015Arg Single submitter
- p.Gly1477Ser Single submitter
- p.Gly29Ser Single submitter
- p.Gly356Arg Single submitter
- p.Gly690Ser Single submitter
- p.His1077Arg Single submitter
- p.His1190Arg Single submitter
- p.Ile524Val Single submitter
- p.Leu1425Phe Single submitter
- p.Leu1550Pro Single submitter
- p.Leu932Val Single submitter
- p.Lys1068Arg Single submitter
- p.Lys1136Arg Single submitter
- p.Lys175Arg Single submitter
- p.Met1438Val Single submitter
- p.Phe1303Leu Single submitter
- p.Phe31= Single submitter
- p.Pro1146Leu Single submitter
- p.Pro1361Leu Single submitter
- p.Pro1365Ala Single submitter
- p.Pro1482Leu Single submitter
- p.Pro348Leu Single submitter
- p.Pro663Leu Single submitter
- p.Ser1047= Single submitter
- p.Ser1389Leu Single submitter
- p.Thr1517Ser Single submitter
- p.Thr333Ala Single submitter
- p.Thr836= Single submitter
- p.Trp1184Arg Single submitter
- p.Val1279Ile Single submitter
- p.Val481Met Single submitter
- p.Ala1638Val No assertion criteria PHRF1-related disorder
- p.Arg1022fs No assertion criteria PHRF1-related disorder
- p.Ser1019fs No assertion criteria PHRF1-related disorder
Uncertain significance 351
Showing the top 300 by review status; the full set is in the sitemap.
- p.Ala114Ser Single submitter ⚠
- p.Ala114Val Single submitter ⚠
- p.Ala1197Ser Single submitter ⚠
- p.Ala1249Gly Single submitter ⚠
- p.Ala1278Thr Single submitter ⚠
- p.Ala127Thr Single submitter ⚠
- p.Ala1308Val Single submitter ⚠
- p.Ala1318Thr Single submitter ⚠
- p.Ala1351Pro Single submitter ⚠
- p.Ala1355Val Single submitter ⚠
- p.Ala1364Val Single submitter ⚠
- p.Ala1381Thr Single submitter ⚠
- p.Ala1382Gly Single submitter ⚠
- p.Ala1414Thr Single submitter ⚠
- p.Ala1420Pro Single submitter ⚠
- p.Ala1420Ser Single submitter ⚠
- p.Ala1492Thr Single submitter ⚠
- p.Ala1515Val Single submitter ⚠
- p.Ala1552Thr Single submitter ⚠
- p.Ala1552Val Single submitter ⚠
- p.Ala176Val Single submitter ⚠
- p.Ala206Val Single submitter
- p.Ala232Pro Single submitter ⚠
- p.Ala232Val Single submitter ⚠
- p.Ala239Val Single submitter ⚠
- p.Ala241Val Single submitter ⚠
- p.Ala284Glu Single submitter ⚠
- p.Ala294Thr Single submitter ⚠
- p.Ala317Val Single submitter ⚠
- p.Ala365Val Single submitter ⚠
- p.Ala424Val Single submitter ⚠
- p.Ala570Ser Single submitter ⚠
- p.Ala593Thr Single submitter ⚠
- p.Ala593Val Single submitter ⚠
- p.Ala610Val Single submitter ⚠
- p.Ala646Glu Single submitter ⚠
- p.Ala646Thr Single submitter ⚠
- p.Ala670Thr Single submitter ⚠
- p.Ala752Gly Single submitter ⚠
- p.Ala842Thr Single submitter ⚠
- p.Ala910Thr Single submitter ⚠
- p.Ala930Val Single submitter ⚠
- p.Ala947Val Single submitter ⚠
- p.Ala95Thr Single submitter ⚠
- p.Ala970Gly Single submitter ⚠
- p.Arg1000Cys Single submitter ⚠
- p.Arg1000His Single submitter ⚠
- p.Arg1016Trp Single submitter ⚠
- p.Arg1018Leu Single submitter ⚠
- p.Arg1041Cys Single submitter ⚠
- p.Arg1046Trp Single submitter ⚠
- p.Arg1053Gln Single submitter ⚠
- p.Arg1053Trp Single submitter ⚠
- p.Arg1062Gln Single submitter ⚠
- p.Arg1062Gly Single submitter ⚠
- p.Arg1079Gln Single submitter ⚠
- p.Arg1087Lys Single submitter ⚠
- p.Arg1090Gln Single submitter ⚠
- p.Arg1092Gln Single submitter ⚠
- p.Arg1092Pro Single submitter PHRF1-related disorder ⚠
- p.Arg1092Trp Single submitter ⚠
- p.Arg1119Gln Single submitter ⚠
- p.Arg1139Trp Single submitter ⚠
- p.Arg1145Gln Single submitter ⚠
- p.Arg1156Gln Single submitter ⚠
- p.Arg1158Gln Single submitter ⚠
- p.Arg1158Trp Single submitter ⚠
- p.Arg1159Lys Single submitter ⚠
- p.Arg1161Gln Single submitter ⚠
- p.Arg1164Trp Single submitter ⚠
- p.Arg1173Trp Single submitter ⚠
- p.Arg1177Leu Single submitter ⚠
- p.Arg1177Trp Single submitter ⚠
- p.Arg1179Gln Single submitter ⚠
- p.Arg1179Trp Single submitter ⚠
- p.Arg1181Cys Single submitter ⚠
- p.Arg1181His Single submitter ⚠
- p.Arg1188Pro Single submitter ⚠
- p.Arg1213Trp Single submitter ⚠
- p.Arg12Gln Single submitter ⚠
- p.Arg12Pro Single submitter ⚠
- p.Arg1301Gln Single submitter ⚠
- p.Arg1377Lys Single submitter ⚠
- p.Arg1383Trp Single submitter ⚠
- p.Arg1419Ile Single submitter ⚠
- p.Arg1419Lys Single submitter ⚠
- p.Arg1549Lys Single submitter ⚠
- p.Arg1631Cys Single submitter ⚠
- p.Arg194His Single submitter ⚠
- p.Arg264Trp Single submitter ⚠
- p.Arg266Gln Single submitter ⚠
- p.Arg277Leu Single submitter ⚠
- p.Arg277Trp Single submitter ⚠
- p.Arg290Gly Single submitter ⚠
- p.Arg336Gln Single submitter ⚠
- p.Arg337Gln Single submitter ⚠
- p.Arg371His Single submitter ⚠
- p.Arg395Trp Single submitter ⚠
- p.Arg462Trp Single submitter ⚠
- p.Arg466Trp Single submitter ⚠
- p.Arg487Cys Single submitter ⚠
- p.Arg527Cys Single submitter
- p.Arg527His Single submitter
- p.Arg588Ser Single submitter ⚠
- p.Arg594His Single submitter ⚠
- p.Arg614Gly Single submitter ⚠
- p.Arg673Gly Single submitter ⚠
- p.Arg673Lys Single submitter ⚠
- p.Arg749Gln Single submitter ⚠
- p.Arg749Trp Single submitter ⚠
- p.Arg778Gln Single submitter ⚠
- p.Arg801Gln Single submitter ⚠
- p.Arg801Trp Single submitter ⚠
- p.Arg826Gln Single submitter ⚠
- p.Arg906Trp Single submitter ⚠
- p.Arg958Trp Single submitter ⚠
- p.Arg994His Single submitter ⚠
- p.Asn100Ser Single submitter ⚠
- p.Asn113Ser Single submitter ⚠
- p.Asn289Ile Single submitter ⚠
- p.Asp103Gly Single submitter ⚠
- p.Asp1072Gly Single submitter ⚠
- p.Asp1236Asn Single submitter ⚠
- p.Asp1236Val Single submitter ⚠
- p.Asp1258Asn Single submitter ⚠
- p.Asp1330Glu Single submitter ⚠
- p.Asp1467Glu Single submitter ⚠
- p.Asp182Tyr Single submitter ⚠
- p.Asp310Gly Single submitter ⚠
- p.Asp44Gly Single submitter ⚠
- p.Asp4Asn Single submitter ⚠
- p.Asp4Gly Single submitter
- p.Asp504Glu Single submitter ⚠
- p.Asp55Asn Single submitter ⚠
- p.Asp675Asn Single submitter ⚠
- p.Asp79Asn Single submitter ⚠
- p.Asp804Ala Single submitter ⚠
- p.Asp834Asn Single submitter ⚠
- p.Cys1512Gly Single submitter ⚠
- p.Cys156Tyr Single submitter ⚠
- p.Cys186Tyr Single submitter ⚠
- p.Gln1379Glu Single submitter ⚠
- p.Gln1429Arg Single submitter ⚠
- p.Gln571Arg Single submitter ⚠
- p.Gln612Glu Single submitter ⚠
- p.Gln722Lys Single submitter ⚠
- p.Gln874Pro Single submitter ⚠
- p.Glu1105Lys Single submitter ⚠
- p.Glu1144Lys Single submitter ⚠
- p.Glu1169Val Single submitter ⚠
- p.Glu1210Lys Single submitter ⚠
- p.Glu1225Val Single submitter ⚠
- p.Glu1293Lys Single submitter ⚠
- p.Glu1385Gly Single submitter ⚠
- p.Glu1559Lys Single submitter ⚠
- p.Glu1640Lys Single submitter ⚠
- p.Glu1648Lys Single submitter ⚠
- p.Glu180Gly Single submitter ⚠
- p.Glu187Ala Single submitter
- p.Glu229Gln Single submitter ⚠
- p.Glu247Lys Single submitter ⚠
- p.Glu248Asp Single submitter ⚠
- p.Glu248Val Single submitter
- p.Glu386Ala Single submitter ⚠
- p.Glu386Val Single submitter ⚠
- p.Glu500Lys Single submitter ⚠
- p.Glu718Gly Single submitter ⚠
- p.Glu74Asp Single submitter ⚠
- p.Glu848Lys Single submitter ⚠
- p.Glu891Gln Single submitter ⚠
- p.Glu939Asp Single submitter ⚠
- p.Glu986Ala Single submitter ⚠
- p.Gly1094Glu Single submitter ⚠
- p.Gly1262Asp Single submitter ⚠
- p.Gly1268Arg Single submitter
- p.Gly1367Val Single submitter ⚠
- p.Gly1464Arg Single submitter ⚠
- p.Gly1505Arg Single submitter
- p.Gly1511Asp Single submitter ⚠
- p.Gly1646Val Single submitter ⚠
- p.Gly190Ser Single submitter ⚠
- p.Gly203Ser Single submitter ⚠
- p.Gly380Glu Single submitter ⚠
- p.Gly43Arg Single submitter ⚠
- p.Gly51Glu Single submitter ⚠
- p.Gly567Arg Single submitter ⚠
- p.Gly56Arg Single submitter ⚠
- p.Gly701Arg Single submitter ⚠
- p.Gly771Arg Single submitter ⚠
- p.Gly837Ser Single submitter ⚠
- p.Gly889Val Single submitter ⚠
- p.His1135Gln Single submitter ⚠
- p.His1135Tyr Single submitter ⚠
- p.His1227Pro Single submitter ⚠
- p.His1327Asn Single submitter ⚠
- p.His1327Gln Single submitter ⚠
- p.His1327Tyr Single submitter ⚠
- p.His1426Gln Single submitter ⚠
- p.His744Arg Single submitter ⚠
- p.Ile135Val Single submitter ⚠
- p.Ile1488Val Single submitter ⚠
- p.Ile155Val Single submitter ⚠
- p.Ile157Ser Single submitter ⚠
- p.Ile887Met Single submitter ⚠
- p.Leu1132Val Single submitter ⚠
- p.Leu1257Pro Single submitter ⚠
- p.Leu1283Pro Single submitter
- p.Leu1525Gln Single submitter ⚠
- p.Leu213Ser Single submitter ⚠
- p.Leu237Val Single submitter ⚠
- p.Leu642Val Single submitter ⚠
- p.Leu667Val Single submitter ⚠
- p.Leu6Val Single submitter ⚠
- p.Leu816Pro Single submitter ⚠
- p.Leu816Val Single submitter ⚠
- p.Lys1003Arg Single submitter ⚠
- p.Lys1048Glu Single submitter ⚠
- p.Lys345Glu Single submitter ⚠
- p.Lys369Glu Single submitter ⚠
- p.Lys668Asn Single submitter ⚠
- p.Met1286Ile Single submitter ⚠
- p.Met1286Val Single submitter ⚠
- p.Met517Leu Single submitter ⚠
- p.Phe1303Ile Single submitter ⚠
- p.Phe130Tyr Single submitter ⚠
- p.Phe152Tyr Single submitter ⚠
- p.Phe161Leu Single submitter ⚠
- p.Phe555Ile Single submitter ⚠
- p.Pro1166Leu Single submitter ⚠
- p.Pro1185Leu Single submitter ⚠
- p.Pro1254Leu Single submitter ⚠
- p.Pro1299Leu Single submitter ⚠
- p.Pro1310Ser Single submitter ⚠
- p.Pro1311Ser Single submitter ⚠
- p.Pro1334Leu Single submitter ⚠
- p.Pro1336Ser Single submitter ⚠
- p.Pro1344Thr Single submitter ⚠
- p.Pro1349Leu Single submitter ⚠
- p.Pro1358Ser Single submitter ⚠
- p.Pro1392Ser Single submitter ⚠
- p.Pro1428Ser Single submitter ⚠
- p.Pro1461Leu Single submitter ⚠
- p.Pro1479Leu Single submitter ⚠
- p.Pro1522His Single submitter ⚠
- p.Pro1546Leu Single submitter ⚠
- p.Pro16Leu Single submitter ⚠
- p.Pro183Leu Single submitter ⚠
- p.Pro215Ser Single submitter ⚠
- p.Pro228Leu Single submitter
- p.Pro265His Single submitter ⚠
- p.Pro27Ser Single submitter ⚠
- p.Pro331Ser Single submitter ⚠
- p.Pro334Ala Single submitter ⚠
- p.Pro348Arg Single submitter ⚠
- p.Pro569Leu Single submitter ⚠
- p.Pro573Ser Single submitter ⚠
- p.Pro578Arg Single submitter ⚠
- p.Pro578Leu Single submitter ⚠
- p.Pro641His Single submitter ⚠
- p.Pro698Leu Single submitter ⚠
- p.Pro723Ala Single submitter ⚠
- p.Pro761Ser Single submitter ⚠
- p.Pro815Ser Single submitter ⚠
- p.Pro835Arg Single submitter ⚠
- p.Pro847Ala Single submitter ⚠
- p.Pro898Ser Single submitter ⚠
- p.Pro922Ser Single submitter ⚠
- p.Pro938Gln Single submitter ⚠
- p.Pro938Thr Single submitter ⚠
- p.Pro940His Single submitter ⚠
- p.Pro974Leu Single submitter ⚠
- p.Ser1001Arg Single submitter ⚠
- p.Ser1019Cys Single submitter ⚠
- p.Ser1019Tyr Single submitter ⚠
- p.Ser1030Leu Single submitter ⚠
- p.Ser1167Gly Single submitter ⚠
- p.Ser1168Trp Single submitter ⚠
- p.Ser1264Ala Single submitter ⚠
- p.Ser1275Leu Single submitter ⚠
- p.Ser1332Leu Single submitter ⚠
- p.Ser1360Cys Single submitter ⚠
- p.Ser1412Asn Single submitter ⚠
- p.Ser1413Arg Single submitter ⚠
- p.Ser1495Asn Single submitter ⚠
- p.Ser1541Leu Single submitter ⚠
- p.Ser1541Trp Single submitter ⚠
- p.Ser1608Asn Single submitter ⚠
- p.Ser250Cys Single submitter ⚠
- p.Ser306Tyr Single submitter ⚠
- p.Ser38Arg Single submitter ⚠
- p.Ser39Asn Single submitter ⚠
- p.Ser48Ile Single submitter ⚠
- p.Ser521Asn Single submitter ⚠
- p.Ser532Cys Single submitter ⚠
- p.Ser589Cys Single submitter ⚠
- p.Ser620Asn Single submitter ⚠
- p.Ser650Leu Single submitter ⚠
- p.Ser734Asn Single submitter ⚠
- p.Ser754Arg Single submitter ⚠
- p.Ser792Phe Single submitter ⚠